Klebsiella michiganensis RC10: VW41_00600
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Entry
VW41_00600 CDS
T03782
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
kmi
Klebsiella michiganensis RC10
Pathway
kmi00270
Cysteine and methionine metabolism
kmi00450
Selenocompound metabolism
kmi00670
One carbon pool by folate
kmi01100
Metabolic pathways
kmi01110
Biosynthesis of secondary metabolites
kmi01230
Biosynthesis of amino acids
kmi04981
Folate transport and metabolism
Module
kmi_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
kmi00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
VW41_00600 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
VW41_00600 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
VW41_00600 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
VW41_00600 (metH)
04980 Cobalamin transport and metabolism
VW41_00600 (metH)
Enzymes [BR:
kmi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
VW41_00600 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AJZ91808
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Position
133231..136914
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AA seq
1227 aa
AA seq
DB search
MSNNVEKLKQQLGERILVLDGGMGTMIQSYRLDESDFRGERFADWPCDLKGNNDLLVLSK
PEIIAAIHYAYFEAGADIVETNTFNSTTIAMADYQMESLSAEINYEAAKLARACADEWTA
RTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTRALVEGGADLIMI
ETVFDTLNAKAAIFAVKAEFDALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHADA
LSFGLNCALGPDELRQYVAELSRIAECYVTAHPNAGLPNAFGEYDLDAEVMAQQIGEWAQ
AGFLNIVGGCCGTTPAHIAAMSAAVAGVAPRKLPELPVACRLAGLEPLNIGADSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVALQQVASGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWEVIEQGLKCIQGKGIVNSISMKEGIEPFIHHAKLVRRYGAAM
VVMAFDEVGQADTRERKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHAMISGGVSNVSFSFRGNEPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELRDAVEDVILNRRDDSTERLLELAEKYRGSKSDDGANAQLAEWRSWDVA
KRLEYSLVKGITEFIEADTEEARQQSTRPIEVIEGPLMAGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPYIEASKEQGSSNGKIVLATVKGDVHDIGKNIVGVVLQCNNYEIIDL
GVMVPGEKILKTAREVGADIIGLSGLITPSLDEMVNVAKEMERQGFTLPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVSALLSATQRDEFVARTRKEYEVVRTQHARKKPR
TPPVTLEVARDNDQPFDWESYTPPVPHRLGVQEVTASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGEEAKRLFKDANDMLDMLHRTKTMTPRGVVGLFPANRVGDDVEIYADETRA
QVKGFSRHLRQQTEKNGFPNYCIADFVAPKHSGKADYIGAFAVTGGIEEDALAGAYDAQH
DDYNKIMVKAVADRLAEAFAEYLHERVRKVYWGYAATENLSNEELIRENYQGIRPAPGYP
ACPEHTEKAAIWALLDVENVIGMKLTESYAMWPGASVSGWYFSHPDSKYFAVAQIQRDQV
EDYARRKGMPVSEVERWLAPNLGYDAD
NT seq
3684 nt
NT seq
+upstream
nt +downstream
nt
gtgagcaacaacgtagagaagctgaagcaacaactgggtgagcgcattctggtgctggac
ggcggtatggggaccatgatccaaagctaccgccttgatgagagcgatttccgcggcgag
cgttttgccgactggccgtgtgatctcaagggcaacaatgacctgctggtgctcagcaaa
ccagaaattatcgccgcgattcactatgcctactttgaagcgggcgccgacatcgtcgaa
accaacacctttaactccaccaccattgcgatggcggattaccaaatggagtcgctgtcg
gcggaaattaactacgaagccgctaagctggcgcgtgcctgtgccgacgaatggacggcg
cgcacgccggaaaaaccgcgctatgtcgccggtgtccttggcccgaccaaccgcacggca
tcgatttccccggacgtgaacgacccggccttccgcaatatcacctttgatcaactggtc
gccgcttaccgtgaatctaccagagcgctggtggaaggcggtgccgacctgataatgatc
gagaccgtgttcgataccctgaacgccaaagcggctatcttcgccgtaaaggcggaattt
gacgcgctcggggttgacctgccgatcatgatttccggtactattaccgatgcgtcaggc
cgtacgctgtccggccagacgacggaagctttttataactccctgcgccacgccgacgcg
ctctcgttcgggctgaactgtgcgctggggccggacgaactgcggcagtacgtggcggaa
ctgtcgcgcattgccgagtgttacgtgaccgctcaccccaatgccgggctgccgaacgct
ttcggcgagtacgatctcgatgcggaagtgatggcgcagcaaataggggaatgggcgcag
gccgggtttctgaacattgtcggcggctgctgcgggacgacgcctgcgcatatcgccgca
atgagcgcggcggtagcaggcgttgcgccgcgcaaactccctgagctgccggttgcctgc
cgcctggccgggcttgagccgctgaatatcggcgcggacagcctgttcgttaacgtcggc
gaacgaaccaacgttaccggctcggctaaattcaagcgtctgatcaaagaagaaaaatac
agtgaagcgctggacgtggccctgcagcaggttgccagcggcgcgcagatcatcgacatc
aacatggatgaggggatgctggatgccgaagcggcgatggtgcgtttcctgaacctgatt
gccggtgagccggatattgcgcgggtgcctatcatgatcgactcctcgaaatgggaagtg
atcgagcaggggctgaagtgcattcagggcaaaggcatcgttaactcgatttccatgaaa
gaaggcattgagccgtttatccatcatgcgaagctggtacgccgctacggcgcggcgatg
gtggtgatggcgttcgacgaagtgggccaggcggatacccgcgagcgtaaaatcgagatt
tgccgccgggcctacaaaattcttaccgaagaggtgggcttcccgccggaagacatcatc
tttgacccgaacatcttcgcggtagcgaccggcatcgaagagcacaacaactacgctcag
gattttatcggcgcctgcgaagacattaagcgcgagctgccccatgcgatgatctccggg
ggcgtgtctaacgtctccttctcattccgcggcaatgagccggtgcgcgaagccattcat
gcggtattcctctattacgcgattcgcaacggcatggacatggggatagtcaacgccgga
caactggcgatttacgacgatctccccgccgagctgcgggatgccgtcgaagacgtcatt
cttaaccgccgcgacgacagcaccgaacggctgctggagctggccgaaaaatatcgcggc
agcaaaagcgatgacggcgccaatgcccaactggcggagtggcgcagctgggacgtggcg
aagcgcctggaatattccctggtgaaaggcatcaccgagtttatcgaagcggataccgaa
gaggcccgccagcagtcgactcgcccaatagaagtgattgaaggcccgctgatggccgga
atgaacgtggtgggggatttgttcggcgaagggaaaatgttcctgccacaggtggtgaaa
tcggcccgcgtgatgaagcaggcggtggcttacctggaaccgtacatcgaagccagcaaa
gagcagggcagcagcaacggtaaaatcgtgctggcaaccgtcaaaggcgacgtgcatgac
atcggcaagaacatcgtcggcgtggtgctgcaatgcaacaactacgagattattgacctt
ggggtgatggtgcccggggagaaaattttgaaaaccgcccgtgaagtcggggccgatatc
attggcctgtccgggctgataaccccgtcgctggacgaaatggtcaacgtggccaaagag
atggagcgccagggctttacgctgccgctgctgattggcggcgcgaccacgtcaaaggcc
catactgcggtgaaaatcgagcagaactatagtgggccaaccgtctacgtgcagaacgcc
tcgcgcaccgtcggcgtggtttctgctctactttcagcaacccagcgcgatgaatttgtc
gcccgcacccgcaaagagtacgaagtggtgcgaacgcagcacgcgcgtaaaaaaccacgc
acgccgccggttacgctggaggtcgcgcgggataacgatcagcctttcgactgggaaagc
tacacgcctccggttccgcatcggctgggcgtgcaggaagtgaccgccagcattgaaacg
ctgcgcaactacatcgactggacgccgttcttcatgacctggtcgctggccgggaagtac
ccacgcattctggaagatgaggttgttggcgaggaggcgaagcgcctgtttaaagacgct
aacgacatgctggatatgctccaccggacgaaaacaatgacgccgcgaggcgtggtcggc
ctgttcccggcaaatcgcgtgggggacgacgtggaaatttatgccgatgaaacacgggcc
caggttaaaggcttcagccgccatctgcgccagcaaacggaaaagaacggcttcccgaac
tactgcattgccgattttgttgcgcctaaacacagcggtaaagccgactacatcggtgct
tttgcggtcaccggcggtattgaagaagacgcgctggcgggggcctacgatgcgcagcac
gatgattacaacaaaatcatggtgaaagcggttgccgaccgcctggccgaagcctttgct
gagtatctgcacgagcgcgtgcgtaaagtctactggggctacgcggccacggaaaacctc
agcaacgaggaactgattcgcgagaattaccagggcattcgcccggctccaggctacccg
gcctgcccggagcacacggaaaaagccgcgatctgggcgctgctggacgtcgaaaacgtg
attggcatgaagctcaccgagtcttacgccatgtggcccggcgcgtcggtttccggctgg
tatttcagccacccggacagcaagtacttcgccgtcgcacagattcagcgcgatcaggtc
gaagactacgcccgacgcaaaggaatgccggtcagcgaggttgaacgctggcttgcgccg
aacctcgggtacgacgccgactga
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