KEGG ORTHOLOGY: K12402

ORTHOLOGY: K12402

Entry

K12402                      KO

Symbol

AP4M1

Name

AP-4 complex subunit mu-1

Pathway

map04142

Lysosome

Disease

H00266

Hereditary spastic paraplegia

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    K12402  AP4M1; AP-4 complex subunit mu-1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K12402  AP4M1; AP-4 complex subunit mu-1
Membrane trafficking [BR:ko04131]
Endosome - Golgi transport
  Others
   AP-4 complex
    K12402  AP4M1; AP-4 complex subunit mu-1

Other DBs

TC:	9.B.278.1.5

Genes

HSA:	9179(AP4M1)

PTR:	738038(AP4M1)

PPS:	100987206(AP4M1)

GGO:	101124613(AP4M1)

PON:	100174275(AP4M1)

PPYG:

129041083(AP4M1)

NLE:	100591045(AP4M1)

HMH:	116810924(AP4M1)

SSYN:

129489607(AP4M1)

MCC:	710944(AP4M1)

MCF:	101866534(AP4M1)

MTHB:

126950480

MNI:	105497233(AP4M1)

CSAB:

103246754(AP4M1)

CATY:

105584419(AP4M1)

PANU:

101003230(AP4M1)

TGE:	112620097(AP4M1)

MLEU:

105543693(AP4M1)

RRO:	104673595(AP4M1)

RBB:	108538130(AP4M1)

TFN:	117072086(AP4M1)

PTEH:

111530196(AP4M1)

CANG:

105513078(AP4M1)

CJC:	100387193(AP4M1)

SBQ:	101032430(AP4M1)

CIMI:

108308016(AP4M1)

ANAN:

105732544(AP4M1)

CSYR:

103275824(AP4M1)

MMUR:

105868307(AP4M1)

LCAT:

123631609(AP4M1)

PCOQ:

105805984(AP4M1)

OGA:	100947918(AP4M1)

MMU:	11781(Ap4m1)

MCAL:

110293978(Ap4m1)

MPAH:

110339123(Ap4m1)

RNO:	304344(Ap4m1)

MCOC:

116068625(Ap4m1)

ANU:	117697769(Ap4m1)

ASYL:

127673389(Ap4m1)

MUN:	110564356(Ap4m1)

CGE:	100774803(Ap4m1)

MAUA:

101837541(Ap4m1)

PROB:

127237137(Ap4m1)

PLEU:

114685021(Ap4m1)

MORG:

121446394(Ap4m1)

MFOT:

126492993

AAMP:

119824633(Ap4m1)

NGI:	103733537(Ap4m1)

HGL:	101725856(Ap4m1)

CPOC:

100718951(Ap4m1)

CCAN:

109691552(Ap4m1)

DORD:

105990969(Ap4m1)

DSP:	122113581(Ap4m1)

PLOP:

125367279(Ap4m1)

NCAR:

124970191

MMMA:

107147109(Ap4m1)

ITI:	101970358(Ap4m1)

OCU:

100343610

OPI:	101525600(AP4M1)

TUP:	102488659(AP4M1)

GVR:	103605483(AP4M1)

CLUD:

112646257(AP4M1)

VVP:	112935752(AP4M1)

NPO:	129519164(AP4M1)

AML:	100481046(AP4M1)

UMR:	103670010(AP4M1)

UAH:	113267882(AP4M1)

UAR:	123777243(AP4M1)

ELK:

111146166

LLV:

125090231

MPUF:

101673602(AP4M1)

MNP:	132026527(AP4M1)

MLK:	131819110(AP4M1)

NVS:	122895269(AP4M1)

ORO:	101365161(AP4M1)

EJU:	114214315(AP4M1)

ZCA:	113931906(AP4M1)

MLX:	117999395(AP4M1)

NSU:	110571969(AP4M1)

LWW:	102745344(AP4M1)

FCA:	101088638(AP4M1)

PYU:	121017600(AP4M1)

PCOO:

112860080(AP4M1)

PBG:	122471992(AP4M1)

PVIV:

125153905(AP4M1)

LRUF:

124519400

LGF:	123589015(AP4M1)

AJU:

106987423

PTG:	102958122(AP4M1)

PPAD:

109251266(AP4M1)

PUC:

125928263

PLEZ:

122210222(AP4M1)

HHV:	120225530(AP4M1)

BTA:	768040(AP4M1)

BOM:	102286369(AP4M1)

BIU:	109578369(AP4M1)

BBUB:

102411477(AP4M1)

BBIS:

104992054(AP4M1)

CHX:	100861048(AP4M1)

OAS:	101107757(AP4M1)

BTAX:

128067038(AP4M1)

CSUM:

138076949(AP4M1)

ODA:	120879874(AP4M1)

CCAD:

122432825(AP4M1)

MREE:

136160353(AP4M1)

OVR:	110144338(AP4M1)

MBEZ:

129545701(AP4M1)

SSC:	110259873(AP4M1)

CFR:	102514063(AP4M1)

CBAI:

105070595(AP4M1)

CDK:	105104806(AP4M1)

VPC:	102535388(AP4M1)

BACU:

103011559(AP4M1)

BMUS:

118881547(AP4M1)

LVE:	103079083(AP4M1)

OOR:	101284655(AP4M1)

LALB:

132506339(AP4M1)

DLE:	111181942(AP4M1)

PCAD:

102976144(AP4M1)

PSIU:

116740057(AP4M1)

NASI:

112399935(AP4M1)

ECB:	100068686(AP4M1)

EPZ:	103561773(AP4M1)

EAI:	106827740(AP4M1)

MYB:	102243937(AP4M1)

MYD:	102773437(AP4M1)

MMYO:

118655702(AP4M1)

MLF:	102429438(AP4M1)

MDT:	132233288(AP4M1)

MYUM:

139008891(AP4M1)

PKL:	118703950(AP4M1)

EFUS:

103285971(AP4M1)

MNA:	107540924(AP4M1)

DRO:	112314888(AP4M1)

SHON:

118986927(AP4M1)

AJM:	119041569(AP4M1)

PDIC:

114495946(AP4M1)

PHAS:

123806251(AP4M1)

MMF:	118642209(AP4M1)

PPAM:

129083825(AP4M1)

HAI:	109377149(AP4M1)

RFQ:	117025112(AP4M1)

PALE:

102892120(AP4M1)

PGIG:

120587443(AP4M1)

PVP:	105310220(AP4M1)

RAY:	107499996(AP4M1)

MJV:	108392034(AP4M1)

TOD:	119241603(AP4M1)

SARA:

101536876(AP4M1)

SFUM:

130036445(AP4M1)

SETR:

126030426(AP4M1)

LAV:	100656171(AP4M1)

TMU:

101340332

ETF:	101643082(AP4M1)

DNM:	101441160(AP4M1)

MDO:	100018108(AP4M1)

GAS:	123244889(AP4M1)

SHR:	100920384(AP4M1)

AFZ:

127560995

PCW:	110202835(AP4M1)

TVP:	118857020(AP4M1)

PBRV:

138142242(AP4M1)

TACU:

119946839(AP4M1)

PCOC:

116239846(AP4M1)

LMUT:

125687696(AP4M1)

ATRC:

139585988(AP4M1)

PHI:	102106407(AP4M1)

CCAE:

111945951(AP4M1)

ACOE:

138101153(AP4M1)

ZLE:	135441861(AP4M1)

MMEA:

130587411(AP4M1)

CCIC:

134055717(AP4M1)

TALA:

116964566(AP4M1)

ACHC:

115338352(AP4M1)

HLE:	104834241(AP4M1)

AGEN:

126034610

HHAR:

128135970(AP4M1)

PPUS:

135173866(AP4M1)

NNI:	104020625(AP4M1)

CBOY:

140645295(AP4M1)

ASN:	102370901(AP4M1)

AMJ:

102559325

PSS:	102459647(AP4M1)

CMY:	114022293(AP4M1)

CCAY:

125629663(AP4M1)

DCC:	119849266(AP4M1)

CPIC:

101947200(AP4M1)

TST:	117869946(AP4M1)

CABI:

116815681(AP4M1)

MRV:	120381834(AP4M1)

ACS:	100557205(ap4m1)

ASAO:

132772621 132772912

PVT:	110086213(AP4M1)

SUND:

121927871(AP4M1)

PBI:	103067047(AP4M1)

PMUR:

107296116(AP4M1)

CTIG:

120307576(AP4M1)

TSR:	106555702(AP4M1)

PGUT:

117669585(AP4M1)

APRI:

131194090(AP4M1)

PTEX:

113450548(AP4M1)

NSS:	113425347(AP4M1)

VKO:	123018858(AP4M1)

PMUA:

114599918(AP4M1)

PRAF:

128416751(AP4M1)

ZVI:	118088596(AP4M1)

HCG:	128322483(AP4M1)

GJA:

107108041

STOW:

125432790(AP4M1)

EMC:	129330507(AP4M1)

XLA:	446550(ap4m1.S)

XTR:	100127610(ap4m1)

NPR:	108793795(AP4M1)

RTEM:

120933514(AP4M1)

BBUF:

120986541(AP4M1)

PWL:	138267862(AP4M1)

MUO:	115457667(AP4M1)

GSH:	117349995(AP4M1)

DRE:	436945(ap4m1)

SRX:	107720677 107742404

SANH:

107675998 107702797

SGH:	107554303 107586161

CCAR:

109092212 122146426

CAUA:

113079420 113093058

CGIB:

127966015

PTET:

122352505(ap4m1)

LROH:

127171589(ap4m1)

OMC:	131548293(ap4m1)

PPRM:

120482357(ap4m1)

RKG:	130082900(ap4m1)

MAMB:

125260066(ap4m1)

CIDE:

127521692

CERY:

137028778(ap4m1)

MASI:

127432290 127433528

TROS:

130546055(ap4m1)

TDW:

130411772

MANU:

129447043(ap4m1)

PDAB:

135779874(ap4m1)

IPU:

108277317

IFU:	128620221(ap4m1)

PHYP:

113524182(ap4m1)

SMEO:

124393271(ap4m1)

TFD:	113650228(ap4m1)

TVC:	132863571(ap4m1)

CGAR:

128545492(ap4m1)

NGRA:

132873572(ap4m1)

TRN:	134332507(ap4m1)

AMEX:

103046827(ap4m1)

CMAO:

118824429(ap4m1)

EEE:	113590925(ap4m1)

CHAR:

105902400(ap4m1)

SPIL:

134080465(ap4m1)

TRU:	101077148(ap4m1)

TFS:	130538042(ap4m1)

TNG:	GSTEN00014684G001

LCO:	104932856(ap4m1)

TBEN:

117469615(ap4m1)

CGOB:

115018588(ap4m1)

PGEO:

117458559(ap4m1)

EMAC:

134871599(ap4m1)

ELY:	117262033(ap4m1)

EFO:	125898758(ap4m1)

SLUC:

116065631(ap4m1)

PFLV:

114566532(ap4m1)

GAT:	120823076(ap4m1)

PPUG:

119215313(ap4m1)

AFB:	129113278(ap4m1)

CLUM:

117742478(ap4m1)

PSWI:

130191284(ap4m1)

CVE:	137888361(ap4m1) 137888748

MSAM:

119895621(ap4m1)

SCHU:

122887732(ap4m1)

CUD:	121519316(ap4m1)

SPUL:

138602674(ap4m1)

LMIX:

132988349(ap4m1)

ALAT:

119030990(ap4m1)

ASTR:

137606233(ap4m1)

MZE:	101470623(ap4m1)

ONL:	100695363(ap4m1)

OAU:	116318244(ap4m1)

OLA:	101159694(ap4m1)

OML:	112142847(ap4m1)

CSAI:

133459983(ap4m1)

XMA:	102224325(ap4m1)

XCO:	114153592(ap4m1)

XHE:	116727937(ap4m1)

PRET:

103459881(ap4m1)

PFOR:

103156623(ap4m1)

PLAI:

106938859(ap4m1)

PMEI:

106918569(ap4m1)

GAF:	122845113(ap4m1)

PPRL:

129370529(ap4m1)

CVG:	107098994(ap4m1)

CTUL:

119793479(ap4m1)

GMU:	124876171(ap4m1)

NFU:	107387170(ap4m1)

KMR:	108228946(ap4m1)

ALIM:

106533650(ap4m1)

NWH:	119419855(ap4m1)

AOCE:

111575139(ap4m1)

EJA:	138194933(ap4m1)

BFRE:

138635555(ap4m1)

MCEP:

125021493(ap4m1)

CSEM:

103395635(ap4m1)

POV:	109645582(ap4m1)

SSEN:

122779824(ap4m1)

SSOE:

131457981(ap4m1)

HHIP:

117774686(ap4m1)

HSP:	118122143(ap4m1)

PPLT:

128457617(ap4m1)

SMAU:

118300235(ap4m1)

LCF:

108877270

SDU:	111221374(ap4m1)

SLAL:

111669796(ap4m1)

XGL:	120802495(ap4m1)

HCQ:	109517176(ap4m1)

SSCV:

125982347(ap4m1)

SBIA:

133492213(ap4m1)

PEE:	133415831(ap4m1)

PTAO:

133467497(ap4m1)

BPEC:

110159872(ap4m1)

ENY:	140360158 140374773

MALB:

109952338(ap4m1)

BSPL:

114869053(ap4m1)

SJO:	128371010(ap4m1)

SSCO:

133994107(ap4m1)

GMH:	115547507(ap4m1)

SASA:

106603583(ap4m1)

STRU:

115154402(ap4m1)

OTW:	112228615(ap4m1)

OMY:	110533710(ap4m1)

OGO:	124009987(ap4m1)

ONE:	115135848(ap4m1)

OKI:	109873250(ap4m1)

OKE:	118390141(ap4m1)

OMM:	135550633(ap4m1)

OCLA:

139418310

SALP:

111951092(ap4m1)

SNH:	120056532(ap4m1)

CCLU:

121574547 121580304

ELS:	105023936(ap4m1)

OEP:	134013870(ap4m1)

SFM:	108934102(ap4m1)

PKI:	111852916(ap4m1)

AANG:

118236612(ap4m1)

AROT:

135264254(ap4m1)

CCOG:

133133604(ap4m1)

LOC:	102698066(ap4m1)

PSPA:

121305690(ap4m1)

PSEX:

120525241(ap4m1)

LCM:	102356362(AP4M1)

CMK:

103188799

RTP:	109922844(ap4m1)

CPLA:

122544407(ap4m1)

HOC:	132835160(ap4m1)

LERI:

129694125(ap4m1)

PMRN:

116949614(AP4M1)

LRJ:	133346948 133348017

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

SKO:

PFLL:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

MRJ:

PORN:

PPOI:

DSV:

RSAN:

RMP:

CVS:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:	106171912 106171913

LLON:

NVE:

EPA:

ATEN:

ADF:	107329356 107339070

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:	114525819 114542466

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_61891

AQU:

ATH:

ALY:

CRB:

CSAT:

104717820 104722531 104730998

EUS:	EUTSA_v10025186mg

BRP:	103834903 103862264

BNA:	106348920 106396522 106427420 106427792 106442118

BOE:	106305936 106307148 106307507

RSZ:	108819164 108842297 130502483

THJ:

104801702

CPAP:

110818721

CIT:

102624963

CIC:	CICLE_v10001124mg

PVY:

116123172

MINC:

123203162 123228846

TCC:	18591439 18591570

GRA:	105769542 105774273

GHI:	107943315 107943585 107957817 121217833

GAB:	108450119 108484490

HSYR:

120180252 120190962 120216446

DZI:	111286701 111312447 111312745

EGR:

104451219

RARG:

115749836

GMX:	100800985 100807075 100811592

GSJ:	114383055 114395389 114408626

PVU:	137823081 137823934

VRA:	106762736 106768884

VAR:	108338231 108342929

VUN:	114164482 114193240

VUM:	124823071 124834219 124834220

CCAJ:

109802556 109815015

APRC:

113846540 113866374

MTR:	11437134 25490218

TPRA:

123897454 123920107

CAM:	101495014 101501240

PSAT:

127083298 127085435 127118674

VVO:	131620665 131660199 131660218

LJA:	130727760 130734151

ADU:	107459243 107493121

AIP:	107609095 107645268

AHF:	112696325 112703259 112758058 112764753

LANG:

109327181 109338469

PCIN:

129294526 129301965 129302446 129317778

QSA:	O6P43_016206 O6P43_018613

FVE:	101293589 101314721

AANS:

126782448 126794074

RCN:	112174066 112180044

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103401986 103441664 103450441

MSYL:

126601765 126604522 126631962

PXB:	103928570 103936584 103964959

PCOX:

137716495 137717523 137737352

ZJU:	107420491 107421265

MNT:	21391098 21404759

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:	8268405 8275770

MEAN:

126665238 126674735

JCU:	105630698 105633839

HBR:	110637137 110637357 110658632

MESC:

110605968 110606672 110609648

POP:

PEU:

PALZ:

PNZ:

JRE:	108991394 109013702

CILL:

CAVE:

AGLU:

QSU:

QLO:	115960762 115974384

TWL:	120008609 120009264

VVI:

VRI:

SLY:

SOT:

SSTN:

SDUL:

CANN:

LBB:

NTA:	107774321 107784896

NSY:

104228720

NTO:

104088455

NAU:

109243053

INI:	109153335 109170529

ITR:	116014384 116026696

SIND:

105158989

OEU:	111371145 111380350

EGT:	105959338 105959339

SSPL:

SMIL:

SHIS:

APAN:

HAN:

ECAD:

LSV:

CCAV:

DCR:

CSIN:

RVL:

AEW:	130758020 130788675

DLT:

127799995

BVG:

104891237

SOE:

110799691

CQI:	110706696 110709744

ATRI:

130810300

MOF:

131161984

NNU:	104595476 104611901

MING:

122077097 122078872

TSS:	122659702 122662612

PSOM:

OSA:

DOSA:

OBR:

OGL:

BDI:

ATS:

TDC:	119353765 119362948

TAES:

123044174 123052054 123187920

TUA:

125536211

LPER:

127332619

LRD:	124672921 124693642

SBI:

8079208

ZMA:

100272249

MFLO:

136492523 136497228 136542623 136550410

SITA:

SVS:

PVIR:

PHAI:

PAUA:

PDA:	103701800 103710989 120109036

EGU:	105041395 105048669

MUS:	103968668 103987441

ZOF:	122019681 122023395

DCT:

110094323

PEQ:	110025590 110029052

AOF:

MSIN:

ACAK:

NCOL:

ATR:

CJF:

SMO:	SELMODRAFT_141330 SELMODRAFT_228695

PPP:

112286228

CRE:	CHLRE_02g146600v5

VCN:	VOLCADRAFT_61858

CSL:	COCSUDRAFT_27229

APRO:

F751_3742

OLU:	OSTLU_13352

OTA:	OT_ostta17g01200

BPG:	Bathy06g02860

MIS:	MICPUN_105619

MPP:	MICPUCDRAFT_66259

RIE:	OCT59_020511

MBR:	MONBRDRAFT_32368

SRE:	PTSG_01942

DDI:	DDB_G0276945(apm4)

DPP:	DICPUDRAFT_54317

DFA:	DFA_11685(apm4)

ACAN:

ACA1_073500

PFA:	PF3D7_1119500

PFD:	PFDG_01880

PFH:	PFHG_01943

PREI:

PRSY57_1117900

PGAB:

PGSY75_1119500

PLAG:

39742422(PADL01_1117600)

PYO:	PY17X_0930600

PCB:	PCHAS_0915700

PBE:	PBANKA_0928600

PVV:	PVVCY_0901770

PKN:	PKNH_0917200

PVX:	PVX_091610

PCY:	PCYB_092560

PMAL:

PMUG01_09028800

PBRS:

92370885(MKS88_002797)

PREL:

PRELSG_0916300

PCOT:

PCOAH_00025130

TAN:

TA14320

TOT:	TOT_020000625

BEQ:	BEWA_024660

BBO:	BBOV_II006760

BMIC:

BMR1_02g03115

BBIG:

BBBOND_0103415

CPV:

cgd8_950

CHO:	Chro.80114

TGO:	TGME49_207390

BBES:

BESB_022210

TET:	TTHERM_00545860

PTM:	GSPATT00024814001 GSPATT00029492001

PTI:	PHATRDRAFT_45284(AP4mu)

FCY:	FRACYDRAFT_205144

TPS:	THAPSDRAFT_31014

AAF:	AURANDRAFT_36844

PIF:	PITG_09875

PSOJ:

PHYSODRAFT_557715

BLAC:

94347045(CCR75_003277)

SPAR:

SPRG_00243 SPRG_03131

TBR:	Tb927.8.7050

TBG:	TbgDal_VIII7270

TCR:	505073.30 509911.70

NGR:	NAEGRDRAFT_37747 NAEGRDRAFT_60743

EHX:	EMIHUDRAFT_432880(Apm4)

GTT:	GUITHDRAFT_147051(AP4M)

» show all

Reference

PMID:11139587

Authors

Aguilar RC, Boehm M, Gorshkova I, Crouch RJ, Tomita K, Saito T, Ohno H, Bonifacino JS

Title

Signal-binding specificity of the mu4 subunit of the adaptor protein complex AP-4.

Journal

J Biol Chem 276:13145-52 (2001)
DOI:10.1074/jbc.M010591200

Sequence

[hsa:9179]

LinkDB

DBGET integrated database retrieval system