Kosakonia sp. SMBL-WEM22: HF650_04345
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Entry
HF650_04345 CDS
T08549
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
kob
Kosakonia sp. SMBL-WEM22
Pathway
kob00010
Glycolysis / Gluconeogenesis
kob00020
Citrate cycle (TCA cycle)
kob00620
Pyruvate metabolism
kob00785
Lipoic acid metabolism
kob01100
Metabolic pathways
kob01110
Biosynthesis of secondary metabolites
kob01120
Microbial metabolism in diverse environments
kob01200
Carbon metabolism
kob01210
2-Oxocarboxylic acid metabolism
Module
kob_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
kob00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
HF650_04345 (aceE)
00020 Citrate cycle (TCA cycle)
HF650_04345 (aceE)
00620 Pyruvate metabolism
HF650_04345 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HF650_04345 (aceE)
Enzymes [BR:
kob01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
HF650_04345 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
PFO_beta_C
Motif
Other DBs
NCBI-ProteinID:
QNQ19036
UniProt:
A0A7H0M9S5
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Position
905839..908502
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AA seq
887 aa
AA seq
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MSERLQNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLSEARKGGVKVAAGTGASNY
VNTIAVEDEPEYPGNLELERRIRSAIRWNAIMTVLRASKKDLELGGHMASFQSSATIYEV
CFNHFFRARNEKDGGDLVYFQGHISPGVYARAFVEGRLTEEQMNNFRQEVHGKGLSSYPH
PKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLKDTSEQTVYAFLGDGEMDEPESK
GAITIATREKLDNLCFIINCNLQRLDGPVTGNGKIVNELEGIFAGAGWNVIKVMWGSRWD
ELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYVREHFFGKYPETAALVADWSDEQIWAL
NRGGHDPKKIYAALKKAQETKGKATVILAHTVKGYGMGDTAEGKNIAHQVKKMNMDGVRY
IRDRFNVPVTDEQVEKLAYVTFDEGSEEHKYLHERRQALKGYLPSRQPKFTEKLDLPALE
DFSQLLEEQNKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYS
PNGQQYTPQDREQVAYYKEDEKGQILQEGINELGAGASWLAAATSYSTNNLPMIPFYIYY
SMFGFQRIGDLCWQAGDQQARGFLVGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYD
PSYAYEVAVIMHDGLQRMYGEKQENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETV
AGNKGKVQLLGSGSILRHVREAAQILANDYGVGSDVYSVTSFTELARDGQDCERWNMLHP
LETPRVPYIAQVMNDAPAVASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRH
HFEVDASYVVVAALGELAKRGEIDKKVVAEAITKFNIDADKVNPRLA
NT seq
2664 nt
NT seq
+upstream
nt +downstream
nt
atgtcagaacgtttacaaaatgacgtggatccgatcgaaactcgcgactggctacaggcg
atcgaatcggtcatccgtgaagaaggtgttgagcgtgctcagtatctgattgaccagctc
ctttctgaagcccgcaaaggcggtgtgaaagtggcagctggcacaggggcgagcaactac
gtaaacactattgccgttgaagatgaaccggaatacccgggcaatctggaactggaacgc
cgtattcgttcagctatccgctggaacgcaatcatgacagttctgcgtgcgtctaaaaaa
gacctcgagctgggcggtcatatggcctccttccagtcttccgcaaccatttacgaagtc
tgctttaaccacttcttccgcgctcgtaacgagaaagatggcggcgatctggtttacttc
cagggccacatctctccgggcgtgtacgcacgtgcatttgttgaaggtcgtctgactgaa
gagcagatgaacaacttccgtcaggaagttcacggtaaaggcctctcctcttacccgcac
ccgaaactgatgccggaattctggcagttcccgaccgtttccatgggtctgggtccgatt
ggtgccatctatcaggcgaagttcctgaaatatctggaacaccgtggtcttaaagatacc
tctgaacagaccgtttacgccttcctcggtgacggtgagatggatgagccggaatccaaa
ggtgcgatcaccatcgctacccgtgagaaactggacaacctctgcttcatcatcaactgt
aacctgcagcgtcttgatggcccagtcaccggtaacggcaaaatcgtcaacgaactggaa
ggcatcttcgcaggtgctggctggaacgtaatcaaggtgatgtggggttctcgttgggac
gagctgctgcgtaaagacaccagcggtaaactgatccagctgatgaacgaaaccgttgat
ggcgactaccagaccttcaaatcgaaagatggtgcgtacgttcgcgaacacttcttcggt
aaatacccggaaactgccgcactggttgcagactggagcgacgagcagatctgggccctg
aaccgcggtggtcacgatccgaagaaaatctacgctgcactgaaaaaagcgcaggaaacc
aaaggcaaagcaactgtcatcctggcccataccgttaaaggttatggcatgggcgacacc
gccgaaggtaaaaacatcgcccaccaggtgaagaaaatgaacatggacggcgtgcgttat
atccgcgaccgcttcaatgttccggtgaccgatgagcaagttgaaaaactcgcttacgtc
accttcgatgaaggctctgaagagcacaaatacctgcacgaacgtcgccaggcgctgaaa
ggctatctgccgtcacgtcagccgaaattcaccgaaaaactggatctgccggcgctggaa
gatttctctcaactgctggaagagcagaacaaagagatctccaccaccatcgccttcgtt
cgtgccctcaacgtgatgctgaagaacaagtcgatcaaagatcgcctggttccgatcatt
gccgacgaagcgcgtaccttcggtatggaaggtctgttccgtcagatcggtatctacagc
ccgaacggccagcagtacaccccgcaggaccgtgagcaggttgcttactacaaagaagac
gagaaaggtcagatcctgcaggaaggtatcaacgaactgggtgctggcgcatcctggctg
gcggctgcgacctcttacagcaccaacaacctgccgatgattccgttctacatctactac
tcgatgttcggtttccagcgtatcggtgacctgtgctggcaggcaggcgaccagcaggcg
cgcggcttcctggtaggcggtacttctggtcgtacgactctgaacggtgaaggtctgcag
cacgaagatggccacagccacatccagtcgctgactatcccgaactgtatctcttacgat
ccgtcttacgcttacgaagttgcggtcatcatgcatgacggtctgcagcgcatgtacggc
gagaaacaagagaacgtttactactacatcaccacgctgaacgaaaactaccacatgccg
gcaatgccggaaggtgccgaggaaggtatccgtaaaggtatctacaaactcgaaaccgtt
gcgggtaacaaaggtaaagttcagctgctgggctccggttctatcctgcgtcacgttcgt
gaagcagcgcagatcctggctaacgactacggcgtaggttctgacgtttatagcgtcacc
tccttcaccgaactggcgcgtgatggccaggattgtgaacgctggaacatgctgcacccg
ctggaaactccgcgcgttccgtacatcgctcaggtgatgaacgacgctccggctgtagca
tctactgactatatgaaactgttcgccgaacaggttcgtacttatgtaccggctgatgat
taccgcgtactgggtaccgatggcttcggtcgttccgacagccgtgaaaacctgcgtcac
cacttcgaagttgatgcttcttacgtggtggtagcagccctgggcgaactggctaaacgt
ggcgaaatcgacaagaaagtggtggcggaagcgatcaccaaattcaacatcgatgcagat
aaagttaacccgcgtctggcgtaa
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