Klebsiella michiganensis E718: A225_0918
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Entry
A225_0918 CDS
T02173
Name
(GenBank) Pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
koe
Klebsiella michiganensis E718
Pathway
koe00010
Glycolysis / Gluconeogenesis
koe00020
Citrate cycle (TCA cycle)
koe00620
Pyruvate metabolism
koe00785
Lipoic acid metabolism
koe01100
Metabolic pathways
koe01110
Biosynthesis of secondary metabolites
koe01120
Microbial metabolism in diverse environments
koe01200
Carbon metabolism
koe01210
2-Oxocarboxylic acid metabolism
Module
koe_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
koe00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
A225_0918
00020 Citrate cycle (TCA cycle)
A225_0918
00620 Pyruvate metabolism
A225_0918
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
A225_0918
Enzymes [BR:
koe01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
A225_0918
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Paralog
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Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
PFO_beta_C
Motif
Other DBs
NCBI-ProteinID:
AFN30735
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Position
976736..979399
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AA seq
887 aa
AA seq
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MSERLPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLSEARKGGVKVAAGASTGGY
VNTIAVEDEPEYPGNLDLERRIRSAIRWNAIMTVLRASKKDLELGGHMASFQSSATFYEV
CFNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTEEQMNNFRQEVHGKGLSSYPH
PKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLKDTSKQTVYAFLGDGEMDEPESK
GAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIINELEGIFGGAGWNVIKVIWGGRWD
ELLRKDTSGKLIQLMEETVDGDYQTFKSKDGAYVREHFFGKYPETAALVADWTDEQIWAL
NRGGHDPKKVYAALKKAQETKGKATVILAHTIKGYGMGDTAEGKNIAHQVKKMNMDGVRY
VRDRFNVPVADADIEKLPYVTFPEGSEEHTYLHAQRQKLHGYLPSRQPNFDEKLELPTLE
DFGPLLEEQNKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYS
PNGQQYTPQDREQVAYYKEDEKGQILQEGINELGAGASWLAAATSYSTNNLPMIPFYIYY
SMFGFQRIGDLCWQAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYD
PSYAYEVAVIMHDGLERMYGEKQENVYYYITTLNENYHMPAMPAGAEEGIRKGIYKLETV
EGSKGKVQLLGSGSILRHVREAAQILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHP
LETPRVPYIAQVMNDAPAVASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRH
HFEVDASYVVVAALGELAKRGEIDKKVVAEAITKFNIDADKVNPRLA
NT seq
2664 nt
NT seq
+upstream
nt +downstream
nt
atgtcagaacgtttaccaaatgacgtggatccgatcgaaactcgcgactggctacaggcg
atcgaatcggtcatccgtgaagaaggtgttgagcgcgctcagtatcttattgaccaactc
ctttctgaagcccgcaaaggcggggtgaaagtggctgctggcgcatcgaccggcggttac
gtgaacactattgccgttgaagatgagccggaatacccgggtaatctggatctggaacgt
cgtatccgttctgcgatccgctggaacgcgattatgaccgttctgcgcgcatcgaaaaaa
gatctcgaactgggcggccacatggcttccttccagtcttccgcaaccttctatgaagtg
tgctttaaccacttcttccgcgcacgcaacgagcaggacggcggcgacctggtttacttc
cagggccacatctctccgggcgtctacgcgcgtgctttcctggaaggtcgtctgactgaa
gagcagatgaacaacttccgtcaggaagttcacggtaaaggtctgtcctcttatccgcac
ccgaaactgatgccggaattctggcagttcccgaccgtctctatgggtctgggcccaatc
ggtgcgatttatcaggctaagttcctgaagtatctggaacaccgcggcctgaaagacact
tccaaacaaaccgtttacgctttcctcggcgacggcgagatggacgagccggaatccaaa
ggcgcgatcaccatcgcgacccgtgagaagctggacaacctggtcttcgttatcaactgt
aacctgcagcgccttgacggcccggttaccggtaatggcaagatcattaacgaactggaa
ggcatctttggcggtgctggctggaacgttatcaaggttatctggggcggacgctgggat
gagctgctgcgtaaagataccagcggtaaactgatccagctgatggaagagaccgttgac
ggtgactaccagaccttcaaatccaaagacggcgcttacgtgcgtgagcacttcttcggt
aaatatccggaaaccgcagcgctggttgccgactggactgacgagcagatctgggccctg
aaccgcggcggtcacgatccgaagaaagtctacgctgcgctgaaaaaagcacaggaaacc
aaaggcaaagccaccgtaatcctcgcccataccattaaaggttacggcatgggtgacacc
gctgaaggtaaaaacatcgctcaccaggttaagaaaatgaacatggacggcgttcgctac
gtccgcgatcgtttcaacgtgccggttgccgatgctgatatcgaaaaactgccgtacgtg
accttcccggaaggttctgaagagcacacctatctgcacgcccagcgtcagaaactgcac
ggctatctgccgagccgtcagccaaacttcgatgagaagctggagctgccgaccctggaa
gatttcggtccgctgctggaagagcagaataaagagatctctaccactatcgcgttcgtt
cgtgccctgaacgtgatgctgaagaacaaatccatcaaagaccgcctcgtgccgatcatc
gccgatgaagcgcgtacctttggtatggaaggcctgttccgtcagattggtatctacagc
ccgaacggtcagcagtacactccgcaggaccgtgagcaggttgcttactacaaagaagac
gagaaaggccagattctgcaggaaggtatcaacgaactgggtgccggtgcatcctggctg
gctgctgcgacctcctacagcaccaacaacctgccgatgatcccgttctacatctactac
tccatgttcgggttccagcgtatcggtgacctgtgctggcaggcaggcgaccagcaggct
cgcggcttcctgatcggcgggacttccggtcgtaccacgctgaacggcgaaggtctgcag
cacgaagatggccacagccacattcagtctctgaccatcccgaactgtatctcttacgat
ccgtcttacgcgtacgaagttgcggtcatcatgcacgatggtctggagcgtatgtacggt
gagaaacaagagaacgtttactactacatcaccacgctgaacgaaaactaccacatgccg
gcaatgccagcaggcgccgaggaaggtatccgtaaaggtatctacaaactcgaaaccgtt
gaaggtagcaaaggtaaagttcagctgctgggctccggttctatcctgcgtcacgtccgt
gaagcagcgcagatcctggccaaagactacggcgtaggctctgacgtttatagcgtcacc
tccttcaccgaactggcgcgtgatggccaggattgtgaacgctggaacatgctgcatccg
ctggaaacgccgcgcgttccgtacatcgctcaggtgatgaacgacgctccggcagtcgca
tctactgactatatgaaactgttcgctgagcaggttcgtacttacgtaccggccgatgat
taccgcgtactgggtaccgacggcttcggtcgctctgacagccgtgaaaacctgcgtcat
cacttcgaagttgacgcttcctacgtggtggtagcagcgctgggcgaactggctaaacgt
ggcgaaatcgataagaaagtggttgcggaagccatcactaaattcaacatcgatgcagat
aaagttaacccgcgtctggcgtaa
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