KEGG   Klebsiella michiganensis M1: HR38_09775
Entry
HR38_09775        CDS       T03349                                 
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase
  KO
K00163  pyruvate dehydrogenase E1 component [EC:1.2.4.1]
Organism
kom  Klebsiella michiganensis M1
Pathway
kom00010  Glycolysis / Gluconeogenesis
kom00020  Citrate cycle (TCA cycle)
kom00620  Pyruvate metabolism
kom00785  Lipoic acid metabolism
kom01100  Metabolic pathways
kom01110  Biosynthesis of secondary metabolites
kom01120  Microbial metabolism in diverse environments
kom01200  Carbon metabolism
kom01210  2-Oxocarboxylic acid metabolism
Module
kom_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:kom00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    HR38_09775 (aceE)
   00020 Citrate cycle (TCA cycle)
    HR38_09775 (aceE)
   00620 Pyruvate metabolism
    HR38_09775 (aceE)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    HR38_09775 (aceE)
Enzymes [BR:kom01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     HR38_09775 (aceE)
SSDB
Motif
Pfam: PDH_E1_M Transketolase_C_1 Transketolase_N Transketolase_C PFO_beta_C
Other DBs
NCBI-ProteinID: AIE68723
UniProt: A0A1Q8YYG0
LinkDB
Position
2053181..2055844
AA seq 887 aa
MSERLPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLSEARKGGVKVAAGASTGGY
VNTIAVEDEPEYPGNLDLERRIRSAIRWNAIMTVLRASKKDLELGGHMASFQSSATFYEV
CFNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTEEQMNNFRQEVHGKGLSSYPH
PKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLKDTSKQTVYAFLGDGEMDEPESK
GAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIINELEGIFGGAGWNVIKVIWGGRWD
ELLRKDTSGKLIQLMEETVDGDYQTFKSKDGAYVREHFFGKYPETAALVADWTDEQIWAL
NRGGHDPKKVYAALKKAQETKGKATVILAHTIKGYGMGDTAEGKNIAHQVKKMNMDGVRY
VRDRFNVPVADADIEKLPYVTFPEGSEEHTYLHAQRQKLHGYLPSRQPNFDEKLELPTLE
DFGPLLEEQNKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYS
PNGQQYTPQDREQVAYYKEDEKGQILQEGINELGAGASWLAAATSYSTNNLPMIPFYIYY
SMFGFQRIGDLCWQAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYD
PSYAYEVAVIMHDGLERMYGEKQENVYYYITTLNENYHMPAMPAGAEEGIRKGIYKLETV
EGSKGKVQLLGSGSILRHVREAAQILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHP
LETPRVPYIAQVMNDAPAVASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRH
HFEVDASYVVVAALGELAKRGEIDKKVVAEAITKFNIDADKVNPRLA
NT seq 2664 nt   +upstreamnt  +downstreamnt
atgtcagaacgtttaccaaatgacgtggatccgatcgaaactcgcgactggctacaggcg
atcgaatcggtcatccgtgaagaaggtgttgagcgcgctcagtatcttattgaccaactc
ctttctgaagcccgcaaaggcggggtgaaagtggctgctggcgcatcgaccggcggttac
gtgaacactattgccgttgaagatgagccggaatacccgggtaatctggatctggaacgt
cgtatccgttctgcgatccgctggaacgcgattatgaccgttctgcgcgcatcgaaaaaa
gatctcgaactgggcggccacatggcttccttccagtcttccgcaaccttctatgaagtg
tgctttaaccacttcttccgcgcacgcaacgagcaggacggcggcgacctggtttacttc
cagggccacatctctccgggcgtctacgcgcgtgctttcctggaaggtcgtctgactgaa
gagcagatgaacaacttccgtcaggaagttcacggtaaaggtctgtcctcttatccgcac
ccgaaactgatgccggaattctggcagttcccgaccgtctctatgggtctgggcccaatc
ggtgcgatttatcaggctaagttcctgaagtatctggaacaccgcggcctgaaagacact
tccaaacaaaccgtttacgctttcctcggcgacggcgagatggacgagccggaatccaaa
ggcgcgatcaccatcgcgacccgtgagaagctggacaacctggtcttcgttatcaactgt
aacctgcagcgccttgacggcccggttaccggtaatggcaagatcattaacgaactggaa
ggcatctttggcggtgctggctggaacgttatcaaggttatctggggcggacgctgggat
gagctgctgcgtaaagataccagcggtaaactgatccagctgatggaagagaccgttgac
ggcgactaccagaccttcaaatccaaagacggcgcttacgtgcgtgagcacttcttcggt
aaatatccggaaaccgcagcgctggttgccgactggactgacgagcagatctgggccctg
aaccgcggcggtcacgatccgaagaaagtctacgctgcgctgaaaaaagcacaggaaacc
aaaggcaaagccaccgtaatcctcgcccataccattaaaggttacggcatgggtgacacc
gctgaaggtaaaaacatcgctcaccaggttaagaaaatgaacatggacggcgttcgctac
gtccgcgatcgtttcaacgtgccggttgccgatgctgatatcgaaaaactgccgtacgtg
accttcccggaaggttctgaagagcacacctatctgcacgcccagcgtcagaaactgcac
ggctatctgccgagccgtcagccaaacttcgatgagaagctggagctgccgaccctggaa
gatttcggtccgctgctggaagagcagaataaagagatctctaccactatcgcgttcgtt
cgtgccctgaacgtgatgctgaagaacaaatccatcaaagaccgcctcgtgccgatcatc
gccgatgaagcgcgtacctttggtatggaaggcctgttccgtcagattggtatctacagc
ccgaacggtcagcagtacactccgcaggaccgtgagcaggttgcttactacaaagaagac
gagaaaggccagattctgcaggaaggtatcaacgaactgggtgccggtgcatcctggctg
gctgctgcgacctcctacagcaccaacaacctgccgatgatcccgttctacatctactac
tccatgttcgggttccagcgtatcggtgacctgtgctggcaggcaggcgaccagcaggct
cgcggcttcctgatcggcgggacttccggtcgtaccacgctgaacggcgaaggtctgcag
cacgaagatggccacagccacattcagtctctgaccatcccgaactgtatctcttacgat
ccgtcttacgcgtacgaagttgcggtcatcatgcacgatggtctggagcgtatgtacggt
gagaaacaagagaacgtttactactacatcaccacgctgaacgaaaactaccacatgccg
gcaatgccagcaggcgccgaggaaggtatccgtaaaggtatctacaaactcgaaaccgtt
gaaggtagcaaaggtaaagttcagctgctgggctccggttctatcctgcgtcacgtccgt
gaagcagcgcagatcctggccaaagactacggcgtaggctctgacgtttatagcgtcacc
tccttcaccgaactggcgcgtgatggccaggattgtgaacgctggaacatgctgcatccg
ctggaaacgccgcgcgttccgtacatcgctcaggtgatgaacgacgctccggcagtcgca
tctactgactatatgaaactgttcgctgagcaggttcgtacttacgtaccggccgatgat
taccgcgtactgggtaccgacggcttcggtcgctctgacagccgtgaaaacctgcgtcat
cacttcgaagttgacgcttcctacgtggtggtagcagcgctgggcgaactggctaaacgt
ggcgaaatcgataagaaagtggttgcggaagccatcactaaattcaacatcgatgcagat
aaagttaacccgcgtctggcgtaa

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