KEGG   Klebsiella michiganensis HKOPL1: J415_01680
Entry
J415_01680        CDS       T03188                                 
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
koy  Klebsiella michiganensis HKOPL1
Pathway
koy00270  Cysteine and methionine metabolism
koy00450  Selenocompound metabolism
koy00670  One carbon pool by folate
koy01100  Metabolic pathways
koy01110  Biosynthesis of secondary metabolites
koy01230  Biosynthesis of amino acids
koy04980  Cobalamin transport and metabolism
koy04981  Folate transport and metabolism
Module
koy_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:koy00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    J415_01680 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    J415_01680 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    J415_01680 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    J415_01680 (metH)
   04980 Cobalamin transport and metabolism
    J415_01680 (metH)
Enzymes [BR:koy01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     J415_01680 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: AHW85902
LinkDB
Position
complement(357629..361312)
AA seq 1227 aa
MSSKVEQLHQQLKARILVLDGGMGTMIQSYRLSEQDFRGERFADWPCDLKGNNDLLVLSK
PDVITAIHDAYFAAGADIIETNTFNSTTIAMADYQMESLSAEINFVAAKLARASADAWTA
RTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDGLVEAYRESTKALVEGGADLILI
ETVFDTLNAKAAIFAVKEEFEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHADA
LTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAAQIREWAE
AGFLNIVGGCCGTTPEHIAAMSRAVAGLPPRQLPEIPVACRLSGLEPLNIGDDSLFVNVG
ERTNVTGSAKFKRLIKEEKYNEALDVARQQVESGAQIIDINMDEGMLDAEAAMTRFLNLI
AGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVEPFIQHAKKVRRYGAAV
VVMAFDEVGQADTRERKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELRDAVEDVILNRRDDGTERLLDLAEKYRGSKTDDTANAQQAEWRSWDVK
KRLEYSLVKGITEFIELDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPYIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDL
GVMVPADKILKTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDSQRDDFVARTRKEYETVRIQHGRKKPR
TPPVTLEAARDNDLAFDWASYTPPVAHRLGVHEVEASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGEEAQRLFKDANELLDKLSAGKALNPRGVVGLFPANRVGDDVEIYRDETRT
HVLTVGHHLRQQTEKVGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAYEAQH
DDYNKIMVKAIADRLAEAFAEYLHERVRKVYWGYAANENLSNEELIRENYQGIRPAPGYP
ACPEHTEKATIWELLEVEKRTGMKLTESFAMWPGASVSGWYFSHPDSKYFAVAQIQRDQV
EDYALRKGMSIAEVERWLAPNLGYDAD
NT seq 3684 nt   +upstreamnt  +downstreamnt
gtgagcagcaaagttgagcaactgcatcagcagttaaaagcacgtattttggttctggat
gggggcatgggcaccatgatccagagctatcgtctgagtgagcaggactttcgcggcgag
cgctttgccgactggccgtgcgacctgaagggcaacaacgacctgctggttctcagcaag
ccggatgtgataaccgctatccacgatgcctattttgcggccggggcggatatcattgaa
accaacacctttaactcgacgaccatcgcgatggcggattaccagatggaatccctgtcg
gcggaaatcaactttgtggcggcgaaactggcccgcgccagcgccgatgcctggaccgca
cgcacgccggaaaaaccgcgctacgtcgcaggggtcctcggcccgactaaccgcacggcg
tccatttctcccgacgtcaacgacccggccttccgcaatatcacctttgacgggctggtg
gaagcctatcgtgaatccaccaaagcgctggtggaaggcggggcggatctgattctgatt
gagacggtgttcgataccctcaacgccaaagcggcgatctttgcggttaaagaggagttt
gaagcgctgggggtcgatctgccgattatgatctccggcaccatcaccgacgcctccggg
cgcacgctgtccggccagaccaccgaagccttttataactcgctgcgccacgccgatgcg
ctgacgtttggcctcaactgcgccctggggccggatgagctgcgccagtacgtgcaggag
ctgtcgcgtatcgccgaatgctacgttaccgcccacccgaacgccggtctgccgaacgcc
tttggcgaatacgacctcgacgccgacacgatggcggcgcaaattcgcgaatgggctgaa
gccggattcctgaatattgtcggcggctgctgcggtaccacgccggaacatatcgccgcc
atgagccgcgcggtggccggcctgccgccgcgccagctgccggaaatccccgtcgcctgt
cgtctttccggccttgagccgctgaatatcggcgatgacagcctgtttgtgaacgtcggc
gaacgcaccaacgttaccggctcggcgaaattcaagcgcctgattaaagaagaaaaatat
aacgaagcgctggatgtggcgcgccagcaggtggaaagcggcgcgcagattatcgatatc
aatatggatgaggggatgctcgacgccgaagcggcaatgacgcgtttcctcaacctgatc
gccggtgagccggatatcgcccgcgtgccgattatgatcgactcctccaaatgggaggtc
atcgaaaagggcctgaagtgtattcagggtaaaggcatcgttaactccatctcgatgaaa
gagggcgttgagccgtttatccagcatgcgaaaaaggtgcgccgctacggggccgccgtc
gtggtgatggcctttgatgaagtgggccaggccgatacccgcgagcggaaaattgaaatt
tgccgccgggcgtacaaaattctcaccgaagaggtgggcttcccgccggaagatatcatc
tttgacccgaatattttcgccgtggcgaccgggattgaagagcacaacaactatgcccag
gactttatcggcgcctgcgaagatatcaaacgcgaactgccgcacgcgctgatctccggc
ggcgtctctaacgtgtcgttctccttccgcggcaacgacccggtgcgcgaggcgattcac
gcggtattcctctactacgccatccgcaacggcatggacatgggcatcgttaacgccggc
cagctggcgatttacgacgaccttcccgccgagctgcgcgatgcggttgaagatgtgatt
ctgaaccgccgcgatgacggcactgaacgtctgctcgatctggcggaaaagtatcgcggc
agcaaaaccgacgataccgctaacgctcagcaggcggaatggcgcagctgggacgtcaaa
aaacgcctcgaatactcgctggttaaaggcattaccgaatttatcgagctcgataccgaa
gaagcccgccagcaggccgcgcgtccgattgaggttatcgaagggccgctgatggacggc
atgaacgtggtcggcgacctgttcggtgaagggaaaatgttcctgccgcaggtggtgaaa
tccgcccgcgtcatgaagcaggcggtggcctacctcgaaccttatattgaggccagcaaa
gagaaaggttccagcaacggcaagatggtcatcgccaccgtgaagggtgacgttcacgac
atcggcaagaatattgtcggcgtggtgctgcagtgtaacaactacgaaatcgtcgacctt
ggcgtgatggtgcctgcggataaaatcctgaaaaccgcccgcgaggttaacgccgacctg
attggcctctccgggctgattacgccgtcgctggatgagatggtcaacgtggcgaaggag
atggagcgtcagggctttactattccgctgctgattggcggcgcaaccacctcgaaagcg
cacacggcggtgaaaatcgagcagaactacagcgggccgacggtctatgtgcagaacgcc
tcgcgcaccgttggcgtggtcgctgcgctgctgtccgatagccagcgcgatgattttgtc
gcccgtacccgcaaagagtacgaaacggtacgtattcagcacgggcgtaaaaagccgcgc
accccgccggtcacgctggaggccgcgcgcgataacgacctggcctttgactgggcaagc
tacaccccgccggtggcccatcgtctgggcgtgcatgaggttgaggccagtatcgaaacc
ctgcgtaactatatcgactggacgccgttctttatgacctggtcgctggccggtaagtat
ccgcgcattctggaagatgaagtggtcggcgaagaggcgcagcgcctgtttaaagacgcc
aacgaactgctggataagctcagcgccgggaaggccctgaatccgcgcggcgtggtgggg
ctgttcccggctaaccgcgtcggcgacgatgttgaaatctatcgcgatgaaacccggact
cacgtgctgacggtggggcatcatctgcgccagcagaccgagaaagtcggctttgccaac
tactgcctggcggattttgtcgcgccgaagctgtcagggaaggcggactatatcggcgcc
tttgcggtgaccggcggccttgaggaagacgcgctggccgacgcctacgaagcgcagcac
gatgactacaacaagattatggtgaaggcgattgctgaccgcctggcggaagcctttgcc
gagtatctgcatgagcgggtgcgtaaggtttactggggctatgcggcgaacgaaaacctc
agcaacgaggagctgatccgcgagaactaccagggaattcgcccggcgccgggctatccg
gcctgcccggagcacaccgaaaaggcgacgatctgggaactgctggaggtggaaaaacgc
accggcatgaagctgacggaatcttttgccatgtggcccggcgcgtcggtttccggctgg
tacttcagccatccggacagcaaatacttcgcggtagcgcaaattcagcgcgaccaggtg
gaagactatgcgttgcgtaaggggatgagcatagcggaagtggagcgctggctggcgccg
aacctcggttacgatgccgactga

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