KEGG   Klebsiella pneumoniae 30660/NJST258_1: KPNJ1_05734
Entry
KPNJ1_05734       CDS       T03176                                 
Name
(GenBank) Dihydrofolate reductase
  KO
K18589  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
Organism
kpa  Klebsiella pneumoniae 30660/NJST258_1
Pathway
kpa00670  One carbon pool by folate
kpa00790  Folate biosynthesis
kpa01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:kpa00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    KPNJ1_05734
   00670 One carbon pool by folate
    KPNJ1_05734
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:kpa01504]
    KPNJ1_05734
Enzymes [BR:kpa01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     KPNJ1_05734
Antimicrobial resistance genes [BR:kpa01504]
 Gene variants
  Trimethoprim resistance genes
   Dihydrofolate reductases
    KPNJ1_05734
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: AHM88011
LinkDB
Position
pNJST258N2:complement(65316..65789)
AA seq 157 aa
MKVSLMAAKAKNGVIGCGPDIPWSAKGEQLLFKALTYNQWLLVGRKTFESMGALPNRKYA
VVTRSGWTSNDDNVVVFQSIEEAMDRLAEFTGHVIVSGGGEIYRETLPMASTLHLSTIDI
EPEGDVFFPSIPNTFEVVFEQHFTSNINYCYQIWKKG
NT seq 474 nt   +upstreamnt  +downstreamnt
ttgaaagtatcattgatggctgcgaaagcgaaaaacggcgtgattggttgcggtccagac
ataccctggtccgcgaaaggggagcagctactttttaaagcattgacctacaatcagtgg
cttctggtgggtcgcaagacgtttgaatctatgggcgcactccccaataggaaatacgcg
gtcgttacccgctcaggttggacatcaaatgatgacaatgtagttgtatttcagtcaatc
gaagaggccatggacaggctagctgaattcaccggtcacgttatagtgtctggtggcgga
gaaatttaccgagaaacattacccatggcctctacgctccacttatcgacgatcgacatc
gagccagagggggatgttttcttcccgagtattccaaataccttcgaagttgtttttgag
caacactttacttcaaacattaactattgctatcaaatttggaaaaagggttaa

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