KEGG   Klebsiella pneumoniae blaNDM-1: FH42_21040
Entry
FH42_21040        CDS       T03440                                 
Symbol
folA
Name
(GenBank) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
kpb  Klebsiella pneumoniae blaNDM-1
Pathway
kpb00670  One carbon pool by folate
kpb00790  Folate biosynthesis
kpb01100  Metabolic pathways
kpb01240  Biosynthesis of cofactors
kpb04981  Folate transport and metabolism
Module
kpb_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:kpb00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    FH42_21040 (folA)
   00670 One carbon pool by folate
    FH42_21040 (folA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    FH42_21040 (folA)
Enzymes [BR:kpb01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     FH42_21040 (folA)
SSDB
Motif
Pfam: DHFR_1 DUF7466
Other DBs
NCBI-ProteinID: AIJ43119
UniProt: C4T9E3
LinkDB
Position
4339568..4340047
AA seq 159 aa
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRLTWESIGRPLPGRKNI
VISSKPGSDDRVQWVSSVEEAIAACGDVEEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVE
GDTHFPDYDPDEWESVFSEFHDADAQNSHSYCFEILERR
NT seq 480 nt   +upstreamnt  +downstreamnt
atgatcagtctgattgcggcgttagcggtagatcgcgtcattggtatggaaaacgccatg
ccatggaacctgcctgccgatctcgcctggttcaaacgcaacacgttaaataagccggtg
gtgatggggcgtctgacctgggaatccattgggcgcccattgccggggcgtaaaaatatc
gtgatcagcagcaaacccggcagcgacgatcgcgtgcagtgggtctcctccgtagaagaa
gcaattgccgcctgcggcgatgtggaagagattatggtgatcggcggcggccgggtgtat
gagcagttcctgccgaaagcgcagaagctctacttgacccatattgatgcggaagtggaa
ggcgatacccatttcccggattacgatccggacgaatgggagtcggtgttcagcgagttt
catgacgccgacgcgcagaactcccatagctactgctttgagatcctcgaacgccgttaa

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