Klebsiella pneumoniae subsp. pneumoniae KPNIH32: KPNIH32_28345
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Entry
KPNIH32_28345 CDS
T03468
Name
(GenBank) dihydrofolate reductase
KO
K18590
dihydrofolate reductase (trimethoprim resistance protein) [EC:
1.5.1.3
]
Organism
kpg
Klebsiella pneumoniae subsp. pneumoniae KPNIH32
Pathway
kpg00670
One carbon pool by folate
kpg00790
Folate biosynthesis
kpg01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
kpg00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
KPNIH32_28345
00670 One carbon pool by folate
KPNIH32_28345
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
01504 Antimicrobial resistance genes [BR:
kpg01504
]
KPNIH32_28345
Enzymes [BR:
kpg01000
]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.3 dihydrofolate reductase
KPNIH32_28345
Antimicrobial resistance genes [BR:
kpg01504
]
Gene variants
Trimethoprim resistance genes
Dihydrofolate reductases
KPNIH32_28345
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DHFR_1
Aq_1974-like
Motif
Other DBs
NCBI-ProteinID:
AIW79678
UniProt:
X5CWF8
LinkDB
All DBs
Position
pKPN-a68:1657..2154
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AA seq
165 aa
AA seq
DB search
MNSESVRIYLVAAMGANRVIGNGPNIPWKIPGEQKIFRRLTEGKVVVMGRKTFESIGKPL
PNRHTLVISRQANYRATGCVVVSTLSHAIALASELGNELYVAGGAEIYTLALPHAHGVFL
SEVHQTFEGDAFFPMLNETEFELVSTETIQAVIPYTHSVYARRNG
NT seq
498 nt
NT seq
+upstream
nt +downstream
nt
atgaactcggaatcagtacgcatttatctcgttgctgcgatgggagccaatcgggttatt
ggcaatggtcctaatatcccctggaaaattccgggtgagcagaagatttttcgcagactc
actgagggaaaagtcgttgtcatggggcgaaagacctttgagtctatcggcaagcctcta
ccgaaccgtcacacattggtaatctcacgccaagctaactaccgcgccactggctgcgta
gttgtttcaacgctgtcgcacgctatcgctttggcatccgaactcggcaatgaactctac
gtcgcgggcggagctgagatatacactctggcactacctcacgcccacggcgtgtttcta
tctgaggtacatcaaaccttcgagggtgacgccttcttcccaatgctcaacgaaacagaa
ttcgagcttgtctcaaccgaaaccattcaagctgtaattccgtacacccactccgtttat
gcgcgtcgaaacggctaa
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