KEGG   Klebsiella variicola KP5-1: A593_15000
Entry
A593_15000        CDS       T03368                                 
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase
  KO
K00163  pyruvate dehydrogenase E1 component [EC:1.2.4.1]
Organism
kpk  Klebsiella variicola KP5-1
Pathway
kpk00010  Glycolysis / Gluconeogenesis
kpk00020  Citrate cycle (TCA cycle)
kpk00620  Pyruvate metabolism
kpk00785  Lipoic acid metabolism
kpk01100  Metabolic pathways
kpk01110  Biosynthesis of secondary metabolites
kpk01120  Microbial metabolism in diverse environments
kpk01200  Carbon metabolism
kpk01210  2-Oxocarboxylic acid metabolism
Module
kpk_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:kpk00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    A593_15000 (aceE)
   00020 Citrate cycle (TCA cycle)
    A593_15000 (aceE)
   00620 Pyruvate metabolism
    A593_15000 (aceE)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    A593_15000 (aceE)
Enzymes [BR:kpk01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     A593_15000 (aceE)
SSDB
Motif
Pfam: PDH_E1_M Transketolase_C_1 Transketolase_N Transketolase_C PFO_beta_C
Other DBs
NCBI-ProteinID: AIE01780
UniProt: A0A087FUV3
LinkDB
Position
3121121..3123784
AA seq 887 aa
MSERLPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLSEARKGGVKVAAGASTGGY
VNTIAVEDEPEYPGNLDLERRIRSAIRWNAIMTVLRASKKDLELGGHMASFQSSATFYEV
CFNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTEEQMNNFRQEVHGKGLSSYPH
PKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLKDTSKQTVYAFLGDGEMDEPESK
GAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIINELEGIFAGAGWNVIKVIWGGRWD
ELLRKDTSGKLIQLMEETVDGDYQTFKSKDGAYVREHFFGKYPETAALVADWTDEQIWAL
NRGGHDPKKVYAALKKAQETKGKATVILAHTIKGYGMGDTAEGKNIAHQVKKMNMDGVRY
VRDRFNVPVADADLEKLPYVTFPEGSEEHTYLHAQRQKLHGYLPSRQPNFSEKLELPTLE
DFAPLLEEQNKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYS
PNGQQYTPQDREQVAYYKEDEKGQILQEGINELGAGASWLAAATSYSTNNLPMIPFYIYY
SMFGFQRIGDLCWQAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYD
PSYAYEVAVIMHDGLERMYGEKQENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETI
EGSKGKVQLLGSGSILRHVREAAQILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHP
LETPRVPYIAQVMNDAPAVASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRH
HFEVDASYVVVAALGELAKRGEIDKKVVADAIAKFDIDAEKVNPRLA
NT seq 2664 nt   +upstreamnt  +downstreamnt
atgtcagaacgtttaccaaatgacgtggatccgatcgaaactcgcgactggctacaggcg
atcgaatcggtcatccgtgaagaaggtgttgagcgtgctcagtatcttattgaccaactc
ctttctgaagcccgcaaaggcggggtgaaagtggctgctggcgcatcgaccggcggttac
gtaaacactattgccgttgaagatgaaccggaatacccgggtaatctggatctggaacgt
cgtatccgttctgcgatccgctggaacgcgatcatgaccgttctgcgcgcatcgaaaaaa
gatctcgaactgggcggccacatggcttccttccagtcttccgcaaccttctacgaagtg
tgcttcaaccacttcttccgcgcacgcaacgagcaggatggcggcgatctagtgtacttc
cagggccacatctctccgggcgtgtatgcgcgtgctttcctggaaggtcgtctgactgaa
gagcagatgaacaatttccgtcaggaagttcacggtaaaggtctgtcctcttatccgcac
ccgaaactgatgccggaattctggcagttcccgaccgtttctatgggtctgggcccaatc
ggggcaatttatcaggctaaattcctgaaatatctggaacaccgtggtctgaaagacacc
tccaaacaaaccgtttatgctttcctgggcgacggtgagatggacgagccggaatctaaa
ggtgcgatcaccatcgccacccgcgagaagctggacaacctggtcttcgttatcaactgt
aacctgcagcgtcttgatggcccggtaacgggtaacggcaaaatcatcaacgaactggaa
ggcatcttcgcgggcgctggctggaacgttatcaaggttatctggggcggtcgttgggat
gagctgctgcgtaaagacaccagcggtaagctgatccagctgatggaagaaaccgttgac
ggcgattaccagaccttcaaatccaaagacggcgcatatgtgcgcgagcacttcttcggt
aaatatccggagaccgcggcgctggttgccgactggactgacgagcagatttgggccctg
aaccgcggcggccacgatccgaagaaagtttacgctgcactgaaaaaagcgcaggaaacc
aaaggcaaagcgaccgtaatcctcgcccataccattaaaggttacggcatgggtgacacc
gctgaaggtaagaacatcgcccaccaggttaagaaaatgaacatggacggcgttcgttac
gtccgagatcgtttcaacgtgccggttgccgatgccgatctcgaaaaactgccgtacgtc
accttcccggaaggttccgaagagcacacctatctgcacgctcagcgccagaaactgcac
ggctatctgccgagccgtcagccgaacttctctgagaagctggagctgccgacgctggaa
gatttcgctccgctgctggaagagcagaataaagagatctctaccactatcgcatttgtt
cgtgccctgaacgtgatgctgaagaacaaatccatcaaagaccgcctcgtgccgattatc
gccgacgaagcgcgtactttcggtatggaaggtctgttccgtcagatcggtatttacagc
ccgaacggccagcagtacaccccgcaggaccgtgagcaggttgcttactacaaagaagac
gagaaaggccagatcctgcaggaagggatcaacgagctgggcgcaggcgcatcctggctg
gctgcggcgacttcttacagcaccaacaacctgccgatgatcccgttctacatctactac
tcgatgttcgggttccagcgtatcggcgacctgtgctggcaggcaggcgaccagcaggct
cgcggcttcctgatcggtggtacttccggtcgtacaacgctgaacggcgaaggtctgcag
cacgaagatggccacagccatattcagtcgctgactatcccgaactgtatctcttacgat
ccgtcctatgcatacgaagtggcggtcatcatgcatgatggcctggagcgtatgtacggt
gagaaacaagagaacgtttactactacatcactacgctgaacgaaaactaccacatgccg
gccatgccggaaggcgccgaggaaggtatccgtaaaggtatctacaaactcgaaaccatt
gaaggtagcaaaggtaaagttcagctgctgggctccggttctatcctgcgtcacgttcgt
gaagcagcgcagatcctggcgaaagactacggcgtgggctctgacgtgtatagcgtcacc
tccttcaccgaactggcgcgtgatggccaggattgcgaacgctggaacatgctgcacccg
ctggaaactccgcgcgtaccgtacatcgctcaggtgatgaacgacgctccggctgtagca
tccactgactatatgaaactgttcgctgagcaggttcgtacttacgtaccggctgatgat
taccgcgtactgggtaccgatggcttcggtcgttccgacagccgtgaaaacctgcgtcac
cacttcgaagtcgatgcttcctatgtggtcgttgcagcgctgggcgaactggctaaacgt
ggtgaaatcgataagaaagtggtggctgacgctatcgcgaaattcgacatcgatgcagaa
aaagttaacccgcgtctggcgtaa

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