KEGG   Klebsiella pneumoniae subsp. pneumoniae MGH 78578 (serotype K52): KPN_03673
Entry
KPN_03673         CDS       T00566                                 
Symbol
acrF
Name
(GenBank) integral transmembrane protein; acridine resistance
  KO
K18142  multidrug efflux pump
Organism
kpn  Klebsiella pneumoniae subsp. pneumoniae MGH 78578 (serotype K52)
Module
kpn_M00696  Multidrug resistance, efflux pump AcrEF-TolC
Brite
KEGG Orthology (KO) [BR:kpn00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:kpn02000]
    KPN_03673 (acrF)
   01504 Antimicrobial resistance genes [BR:kpn01504]
    KPN_03673 (acrF)
Transporters [BR:kpn02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   KPN_03673 (acrF)
Antimicrobial resistance genes [BR:kpn01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump AcrEF-TolC [MD:M00696]
    KPN_03673 (acrF)
SSDB
Motif
Pfam: ACR_tran MMPL SecD_SecF_C DUF3561
Other DBs
NCBI-ProteinID: ABR79065
UniProt: A6TET1
LinkDB
Position
4034492..4037602
AA seq 1036 aa
MSKFFIHRPVFAWVLAIIMMIAGGLAILQLPIAQYPTIAPPAVAISATYPGADAQTVQDT
VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFKSGTDPDIAQVQVQNKLQLATPLLPQ
EVQQQGISVEKSSSSFLLVAGFISDNPTTTQDDISDYVASNVKDPISRLNGVGDVQLFGA
QYAMRVWLDGNLLNKYNLTPVDVINALQVQNDQIAAGQLGGTPALKGQQLNASIIAQTRL
KDPQEFGKVTLRVNADGSVVHLKDVARIELGGENYNVVARINGKPASGLGIKLATGANAL
DTATAIKAKLAELQPYFPQGMKVVYPYDTTPFVKISIHEVVKTLFEAIILVFLVMYLFLQ
NMRATLIPTIAVPVVLLGTFAVLSMFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM
VEEKLSPKEATEKSMSQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL
SVLVALVLTPALCATLLKPASAEHHEKKGFFGWFNARFDRSVNHYTNSVSGILRGTGRYL
VIYLLIVVGMAVLFMRLPTSFLPDEDQGVFLTMIQLPSGATQERTQKVLDTVTDYYLHNE
KANVESVFTVNGFSFSGQGQNSGMAFVSLKPWEARSGDKNSVESIIKRATVAFSQIKDAM
VFPFNMPAIIELGTATGFDFELIDQGGLGHTALTQARNQLLGMVKQHPDQLVRVRPNGLE
DTPQFKLDVDQEKAQALGVSLSDINETISAALGGYYVNDFIDRGRVKKVYVQADAHFRML
PSDINNMYVRSANGEMVPFSAFVTSRWIYGSPRLERYNGLPSMEILGEASPGKSTGEAMA
LMETLASKLPSGIGYDWTGMSYQERLSGNQAPALYAISLIVVFLCLAALYESWSIPFSVM
LVVPLGVIGALLAATLRGLNNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGIIE
ATLEASRMRLRPILMTSLAFILGVMPLVISHGAGSGAQNAVGTGVMGGMLTATLLAIFFV
PVFFVVVRRRFTRHAE
NT seq 3111 nt   +upstreamnt  +downstreamnt
atgtctaagttttttattcatcgaccggtcttcgcctgggtgctggccatcattatgatg
attgccggcggcctggccattctgcagctgccgatagctcagtacccgacaatcgcccct
cctgcggtagcgatctccgccacctaccccggtgcagatgcccagaccgtgcaggatacg
gtcacccaggttatcgagcagaacatgaacggcatcgacaatctgatgtatatgtcgtcg
accagcgactctgccggttcggtaaccattacgctcacctttaaatcgggtaccgatccc
gatattgcccaggttcaggtgcaaaacaaactgcagctggccacgccgctgctgccccag
gaagtacagcagcaggggattagcgtcgagaaatccagtagcagcttcctgttggtcgcc
ggctttatctctgataacccgaccaccacccaggacgatatctctgactatgtcgcctcc
aatgtcaaagatcctattagccgcctcaacggcgtgggcgatgtgcagctgttcggcgcg
caatacgccatgcgcgtctggctggatggcaacctgctgaataaatacaacctgacgccg
gtggacgtcatcaatgcgctgcaggtccagaacgatcagatcgccgcgggtcagctcggc
ggtacgccagcgctgaaaggccaacagttgaacgcgtcaatcatcgctcagacgcggctc
aaagatccgcaggagtttggcaaggtcacgctgcgggtcaatgccgatggctctgtcgtc
catctgaaagacgtcgcccgcattgagctggggggagagaactataacgttgtcgccaga
attaacggtaaacctgcctctggtctgggtattaagcttgcgaccggcgccaacgccctg
gataccgccaccgcgattaaagcgaagctggccgagctgcagccctacttccctcagggg
atgaaggtggtttatccgtatgatacgacccctttcgtcaaaatctccattcacgaagtg
gtcaaaacgctttttgaagcaattattctcgtctttcttgtcatgtatctgttcctgcag
aacatgcgcgcaacgctcattccaaccattgccgtacccgtggtgctgttgggaaccttc
gcggtattgtcgatgtttggctactccatcaacacgctgacaatgtttggcatggtgttg
gcgataggtctgctggtcgatgacgctatcgtagtagtggaaaacgtcgaacgtgtgatg
gttgaggagaagctctcgccaaaagaagcgacggaaaaatctatgtcgcagatccaggga
gcgctggtgggtatcgccatggtgctctccgcagtatttgtcccgatggcctttttcggc
ggctcaaccggcgcgatttatcgtcagttttcaatcaccatcgtctccgccatggcgctc
tccgtgctggttgcgctggtactgactccggcgctctgcgccacgttgttgaagccagcc
tcagctgaacaccatgagaaaaaaggatttttcggctggtttaacgcccgcttcgaccgg
agcgttaaccactataccaacagcgtcagcggtattttacgtggaactggccgttatctg
gtgatctacctgctgatcgtcgtggggatggccgtgctgttcatgcgcttgcccacgtcc
tttctgcccgacgaagaccagggcgtcttcctgaccatgatccagctaccgtccggtgct
acccaggagcgcacgcagaaggtcctggatacggtgacagactactacctgcataacgag
aaggccaacgtcgaaagcgtctttaccgttaacggcttcagcttcagcggccagggacaa
aactccggtatggcgtttgtcagcctgaagccctgggaagcacgcagcggcgataaaaac
agcgtggagtccatcatcaagcgggccaccgtagcctttagccagatcaaagacgccatg
gttttcccgttcaacatgccagccattattgagctgggtaccgccaccggcttcgacttt
gaactgatcgaccagggcggactcggtcataccgctctgacccaggcgcgcaatcaactg
ctgggcatggtgaaacagcatccggatcagctggttcgggtacgccctaatgggctggaa
gatacccctcagttcaaactggatgtcgatcaggaaaaagcgcaggcgctgggcgtatcg
ctctccgatatcaatgaaacgatatcagccgcgctgggcggatactacgtcaatgacttt
attgaccgcggccgcgtgaaaaaagtgtacgttcaggctgatgcccacttccgtatgctg
ccgagcgacattaacaacatgtatgttcgtagcgccaacggcgaaatggtgccgttctcc
gcctttgtcacttcacgctggatatatggctcgccgcgcctggagcgctacaacgggttg
ccatctatggagatcctcggtgaagcttcgccaggcaaaagtaccggggaagccatggcg
ctgatggaaacgctggccagtaaactgccgagcggcatcggttatgactggaccgggatg
tcttaccaggaacggctctccggcaaccaggcgcctgcgctctatgccatctcgctgatc
gtcgtcttcctgtgtctggcggcgctgtatgagagctggtcgatccccttctcagtcatg
ttagtggttccgctgggggtcattggcgcgctgttagccgccacgctgcgtgggctgaat
aatgacgtttacttccaggtcggactcttgaccacgatcggtttgtcggccaagaatgcg
atcctgatcgtcgagttcgccaaggatctgatggagaaagaagggaaagggatcattgag
gccacgctggaggcatcgcggatgcgcctgcggcctattctgatgacctctctggccttt
attctcggggtcatgccgctggtgattagccatggtgccggcagcggggcgcagaatgcg
gttggcaccggcgtgatgggcgggatgctgaccgcgacgctgctggcgatcttctttgtt
ccggtgttctttgtggtcgttagacgacgctttacccggcacgctgaataa

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