Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044 (serotype K1): KP1_0257
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Entry
KP1_0257 CDS
T00910
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
kpu
Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044 (serotype K1)
Pathway
kpu00270
Cysteine and methionine metabolism
kpu00450
Selenocompound metabolism
kpu00670
One carbon pool by folate
kpu01100
Metabolic pathways
kpu01110
Biosynthesis of secondary metabolites
kpu01230
Biosynthesis of amino acids
kpu04980
Cobalamin transport and metabolism
kpu04981
Folate transport and metabolism
Module
kpu_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
kpu00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
KP1_0257 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
KP1_0257 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
KP1_0257 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
KP1_0257 (metH)
04980 Cobalamin transport and metabolism
KP1_0257 (metH)
Enzymes [BR:
kpu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
KP1_0257 (metH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
BAH61157
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All DBs
Position
270443..274216
Genome browser
AA seq
1257 aa
AA seq
DB search
MPVVVFSAPVVYASMVCWLFGLSRALSGASVSSKVEQLHQQLKERILVLDGGMGTMIQGY
RLSEQDFRGERFADWPCDLKGNNDLLVLSKPEVIREIHDAYFEAGADIVETNTFNSTTIA
MADYQMESLSAEINFAAAKLARASADAWTARTPEKPRYVAGVLGPTNRTASISPDVNDPA
FRNITFDQLVAAYRESTRALVEGGVDLILIETVFDTLNAKAAIYAVKEELEALGVDLPLM
ISGTITDASGRTLSGQTTEAFYNSLRHAEALSFGLNCALGPDELRQYVQELSRIAECYVT
AHPNAGLPNAFGEYDLDADTMATQIREWAEAGFLNIVGGCCGTTPEHIAAMSRAVAGLPP
RQLPEIAVACRLAGLEPLNIGDDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQ
VESGAQIIDINMDEGMLDAEAAMVRFLNLIAGEPDIARVPIMIDSSKWEVIEKGLKCIQG
KGIVNSISMKEGVESFIHHAKLVRRYGAAVVVMAFDEVGQADTRERKIEICRRAYKILTE
EVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNVSFSFR
GNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPGELRDAVEDVILNRRDDSTER
LLELAEKYRGSKADDGANAQQAEWRTWEVKKRLEYSLVKGITEFIEQDTEEARQQAARPI
EVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASKEQGSSNGKMV
IATVKGDVHDIGKNIVGVVLQCNNYEIIDLGVMVPADKILKTAKEVNADLIGLSGLITPS
LDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVSAL
LSDTQRDEFVARTRKEYETVRIQHGRKKPRTPPVTLAAARENDLAFDWESYTPPVAHRLG
VQTVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGEEAQRLFKDANELLDKLSAE
KTLNPRGVVGLFPANRVGDDIEIYRDETRTHVLTVSHHLRQQTEKVGFANYCLADFVAPK
LSGKADYIGAFAVTGGLEEDALADAYEAQHDDYNKIMIKAIADRLAEAFAEYLHEKVRKV
YWGYAANENLSNEELIRENYQGIRPAPGYPACPEHTEKGTIWQLLDVEAHTGMKLTESFA
MWPGASVSGWYFSHPDSKYFAVAQIQRDQVEDYALRKGMTPAEVERWLAPNLGYDAD
NT seq
3774 nt
NT seq
+upstream
nt +downstream
nt
ttgcccgttgttgtcttttccgctccggtggtttatgccagtatggtttgttggctattt
ggcctgagtcgagcgttgtcgggagcaagtgtgagcagcaaagttgagcaactgcatcag
cagttaaaagaacgtattctggttctggatgggggcatgggcaccatgatccagggctat
cgtctgagtgagcaggactttcgcggtgagcgctttgctgactggccgtgcgacctgaaa
ggcaacaacgacctgctggtgctcagcaaacccgaagtgatccgcgagatccacgacgcc
tatttcgaggccggcgcggatatcgttgagaccaacacctttaactcgacgaccatcgcg
atggcggattaccagatggaatccctgtcggccgagatcaactttgccgcggcgaagctg
gcccgcgccagcgccgacgcctggacggcccgcacgccggaaaaaccgcgctatgtcgcg
ggcgtgcttggcccgaccaaccgcaccgcttctatttcgcctgatgtgaacgatccggcg
ttccgtaatattacctttgaccagctggtggccgcctatcgcgaatccacccgggcgctg
gtggaaggcggcgtggatctgatcctgattgaaacggtatttgacaccctgaacgctaaa
gcggctatctatgcggtgaaagaggagctggaggcgttaggcgttgacctgccgctgatg
atctccgggaccattaccgatgcctccggccgcacgctttccggacagaccaccgaagcc
ttttataactcgctgcgtcacgccgaagccttatcgtttggtctgaactgcgccctcggg
ccggacgagctgcggcagtacgtccaggagctgtcgcgcattgccgaatgctacgtcacc
gcgcacccgaacgccggcctgcccaacgctttcggcgaatacgatctggacgccgacacc
atggcgacgcaaattcgcgaatgggcggaagccggtttcctcaatatcgttggcggctgc
tgcggtaccaccccggagcatatcgccgccatgagccgggcggtagcgggcctgccgccg
cgtcagttgccggaaattgcggtggcctgccgcctcgccggcctggagccgttgaatatc
ggcgacgatagcctgttcgttaacgtcggtgaacgaactaacgtcaccggctcggcgaaa
tttaagcggctgattaaagaagagaagtacagcgaagcgctggacgttgcgcgtcagcag
gtggaaagcggcgcgcagattatcgatatcaacatggacgaggggatgctcgacgcggaa
gcggcgatggtgcgtttccttaacctgattgccggcgagccggacattgcccgcgtgccg
atcatgattgactcctccaagtgggaagtcattgaaaagggcctgaaatgtattcagggc
aaaggcatcgttaactcgatttcgatgaaagagggcgtcgaatcctttatccaccatgcg
aaactggttcgccgctacggcgccgcggtggtggtgatggctttcgacgaggttggtcag
gccgacacccgcgaacgtaaaattgagatttgccgtcgcgcctacaaaatcctaaccgaa
gaggtcggcttcccgccggaagatattatcttcgaccccaatatctttgccgtcgccacc
ggtatcgaagagcataacaactacgcacaggactttatcggcgcctgcgaagacatcaaa
cgcgagctgccgcatgcgctaatctccggcggggtctccaacgtctccttctccttccgc
ggtaatgacccggtacgtgaggcgatccacgccgtattcctctactacgcgatccgcaac
ggcatggacatggggatcgtcaacgccggtcagctggccatctatgatgacctcccgggc
gagctgcgcgacgcggtcgaagacgtgatcctcaaccgccgcgatgacagtaccgaacgg
ttacttgagctggcggaaaaatatcgcggcagcaaagcggacgacggcgcgaatgcccag
caggcggagtggcgcacctgggaagtgaaaaaacgcctcgaatattcgctggttaagggc
attaccgaatttatcgaacaggacaccgaagaagcgcgtcagcaggccgcccgcccgatt
gaggtcattgaagggccgctgatggacggcatgaacgtggtcggcgatctgttcggcgaa
ggcaaaatgttcctgccgcaggtggtgaaatccgcccgtgtaatgaaacaggcggtggcc
taccttgagccgtttattgaagccagtaaagagcagggctccagtaacggcaaaatggtg
attgccacggtaaaaggcgacgttcatgacattggcaaaaacatcgtcggcgtggtgctg
cagtgcaataactacgaaatcatcgatcttggcgtgatggtcccggcggataaaattctc
aaaacggccaaagaggtaaacgcggatctaattggtctttccgggctgattaccccatcg
ctggacgagatggttaatgtggcgaaagagatggagcgccagggctttaccatcccgctg
ctgataggcggcgcgaccacctcgaaagcgcatacggcggtgaaaatcgagcagaactac
agcggcccgaccgtttacgtacagaacgcctcgcgcaccgtcggcgtggtgtctgcgctg
ctctcggacacgcagcgcgacgagtttgtcgcccgcacgcgcaaagagtatgaaacggtg
cgtatccagcatgggcgtaaaaaaccgcgtacgccgccagtgacccttgccgccgcgcgg
gaaaacgatctggcctttgactgggagagctacacgccgccggtggctcatcgtctggga
gtacagacggtggaagccagtatcgagactctgcgcaactacatcgactggacgccgttc
ttcatgacctggtcgctggcgggtaaatatccgcgcattctggaagatgaagtggtaggg
gaagaggcgcagcgcctgttcaaagatgctaacgagctgctggataagctgagcgcagag
aaaaccctgaacccgcgcggcgtggtgggtctgttcccggccaaccgcgtgggcgacgat
attgaaatctatcgcgatgaaacccgcacccacgtgctgacggtgagccatcatctgcgc
cagcagacggagaaggttggcttcgccaactactgcctcgccgattttgtcgcgccgaag
ctgagcggcaaggcggactacatcggcgccttcgccgtgaccggcggcctggaagaggac
gcgctggcggacgcctatgaagcgcagcatgatgactataacaagatcatgatcaaggcc
atcgccgatcgcctggcggaggcctttgccgagtatctgcatgagaaagtgcgcaaggtt
tactggggatatgcggccaatgagaacctcagcaatgaggagcttattcgcgagaactac
caggggatccgaccggcgccgggatatccggcctgtccggagcacaccgaaaaggggacc
atctggcagctactggacgtcgaagcccataccggcatgaagctcaccgaatcgttcgcc
atgtggccgggcgcatcggtttccggctggtacttcagccatccggatagcaagtacttc
gccgtggcgcagatccagcgcgatcaggtcgaagattacgcgctgcgtaaaggaatgacg
ccggcggaggtcgagcgctggttagcgcctaatctgggctatgatgcggactag
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integrated database retrieval system
