Klebsiella pneumoniae subsp. pneumoniae KPNIH29: KPNIH29_01280
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Entry
KPNIH29_01280 CDS
T03465
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
kpv
Klebsiella pneumoniae subsp. pneumoniae KPNIH29
Pathway
kpv00270
Cysteine and methionine metabolism
kpv00450
Selenocompound metabolism
kpv00670
One carbon pool by folate
kpv01100
Metabolic pathways
kpv01110
Biosynthesis of secondary metabolites
kpv01230
Biosynthesis of amino acids
kpv04980
Cobalamin transport and metabolism
kpv04981
Folate transport and metabolism
Module
kpv_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
kpv00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
KPNIH29_01280 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
KPNIH29_01280 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
KPNIH29_01280 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
KPNIH29_01280 (metH)
04980 Cobalamin transport and metabolism
KPNIH29_01280 (metH)
Enzymes [BR:
kpv01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
KPNIH29_01280 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AIX67265
LinkDB
All DBs
Position
265364..269047
Genome browser
AA seq
1227 aa
AA seq
DB search
MSSKVEQLHQQLKERILVLDGGMGTMIQGYRLSEQDFRGERFADWPCDLKGNNDLLVLSK
PEVIREIHDAYFEAGADIIETNTFNSTTIAMADYQMESLSAEINFAAAKLARASADAWTA
RTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTRALVEGGVDLILI
ETVFDTLNAKAAIYAVKEELEALGVDLPLMISGTITDASGRTLSGQTTEAFYNSLRHAEA
LSFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMATQIREWAE
AGFLNIVGGCCGTTPEHIAAMSRAVAGLPPRQLPEIAVACRLAGLEPLNIGDDSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVESFIHHAKLVRRYGAAV
VVMAFDEVGQADTRERKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPRELRDAVEDVILNRRDDSTERLLELAEKYRGSKADDGANAQQAEWRTWEVK
KRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPFIEASKEQGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIIDL
GVMVPADKILKTAKEVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVSALLSYTQRDEFVARTRKEYETVRIQHGRKKPR
TPPVTLAAARENDLAFDWESYTPPVAHRLGVQTVEASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGEEAQRLFKDANELLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRT
HVLTVSHHLRQQTEKVGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAYEAQH
DDYNKIMIKAIADRLAEAFAEYLHEKVRKVYWGYAANENLSNEELIRENYQGIRPAPGYP
ACPEHTEKATIWELLDVEAHTGMKLTESFAMWPGASVSGWYFSHPDSKYFAVAQIQRDQV
EDYALRKGMTPAEVERWLAPNLGYDAD
NT seq
3684 nt
NT seq
+upstream
nt +downstream
nt
gtgagcagcaaagttgagcaactgcatcagcagttaaaagaacgtattctggttctggat
gggggcatgggcaccatgatccagggctatcgtctgagtgagcaggactttcgcggtgag
cgctttgctgactggccgtgcgacctgaaaggcaacaacgacctgctggtgctcagcaaa
cccgaagtgatccgcgagatccacgacgcctatttcgaggccggcgcggatatcattgag
accaacacctttaactcgacgaccatcgcgatggcggattaccagatggaatccctgtcg
gccgagatcaactttgccgcggcgaagctggcccgcgccagcgccgacgcctggacggcc
cgcacgccggaaaaaccgcgctatgtcgcgggcgtgcttggcccgaccaaccgcaccgcc
tctatctcgcctgatgtgaacgatccggcgttccgtaatattacctttgaccagctggtg
gccgcctatcgcgaatccacccgggcgctggtggaaggcggcgtggatctgatcctgatt
gaaacggtgtttgacaccctgaacgctaaagcggccatctatgcggtgaaagaggaactg
gaggcgttaggcgttgacctgccgctgatgatctccgggaccattaccgatgcctctggc
cgcacgctttccggacagaccaccgaagccttttataactcgctgcgtcacgccgaagcc
ttatcgtttggtctgaactgcgccctcgggccggacgagctgcggcagtacgtccaggag
ctgtcgcgcattgccgaatgctacgtcaccgcgcacccgaacgccggcctgcccaacgcc
ttcggcgaatacgatctggacgccgacaccatggcgacgcaaattcgcgaatgggcggaa
gccggtttcctcaatatcgttggcggctgctgcggtaccaccccggagcatatcgccgcc
atgagccgggcggtagcgggcctgccgccgcgtcagttgccggaaattgcggtggcctgc
cgcctcgccggcctggagccgttgaatatcggcgacgatagcctgttcgttaacgtcggt
gaacgaactaacgtcaccggctcggcgaaatttaagcggctgattaaagaagagaagtac
agcgaagcgctggacgttgcgcgtcagcaggtggaaagcggcgcgcagattatcgatatc
aacatggacgaggggatgctcgacgcggaagcggcgatggtgcgtttccttaacctgatt
gccggcgagccggacattgcccgcgtgccgatcatgattgactcctccaagtgggaagtc
attgaaaagggcctgaaatgtattcagggcaaaggcatcgttaactcgatttcgatgaaa
gagggcgtcgaatcctttatccaccatgcgaaactggttcgccgctacggcgccgcggtg
gtggtgatggctttcgacgaggttggtcaggccgacacccgcgaacgtaaaattgagatt
tgccgtcgcgcctacaaaatcctcaccgaagaggtcggcttcccgccggaagatattatc
ttcgaccccaatatctttgccgtcgccaccggtatcgaagagcataacaactacgcacag
gactttatcggcgcctgcgaagacatcaaacgcgagctgccgcatgcgctaatctccggc
ggggtctccaacgtctccttctccttccgcggtaatgacccggtacgtgaggcgatccac
gccgtattcctctactacgcgatccgcaacggcatggacatggggatcgtcaacgccggt
cagctggccatctatgatgacctcccgcgcgagctgcgcgacgcggtcgaagacgtgatc
ctcaaccgccgcgatgacagtaccgaacggttacttgagctggcggaaaaatatcgcggc
agcaaagcggacgacggcgcgaatgcccagcaggcggagtggcgcacctgggaagtgaaa
aaacgcctcgaatattcgctggtgaagggcattaccgaatttatcgaacaggacaccgaa
gaagcgcgtcagcaggccgcccgcccgattgaggtcattgaagggccgctgatggacggc
atgaacgtggtcggcgatctgttcggcgaaggcaaaatgttcctgccgcaggtggtgaaa
tccgcccgtgtaatgaaacaggcggtggcctaccttgagccgtttattgaagccagtaaa
gagcagggctccagtaacggcaaaatggtgattgccacggtaaaaggcgacgttcatgac
attggcaaaaacatcgtcggcgtggtgctgcagtgcaataactacgaaatcatcgatctt
ggcgtgatggtcccggcggataaaattctcaaaacggccaaagaggtaaacgcggatcta
attggtctttccgggctgattaccccatcgctggacgagatggttaacgtggcgaaagag
atggagcgccagggctttaccatcccgctgctgataggcggcgcgaccacctcgaaagcg
catacggcggtgaaaatcgagcagaactacagcggcccgaccgtttacgtacagaacgcc
tcgcgcaccgtcggcgtggtgtctgcgctgctctcgtacacgcagcgcgacgagtttgtc
gcccgcacgcgcaaagagtatgaaacggtgcgtatccagcatgggcgtaaaaaaccgcgt
acgccgccggtgacccttgccgccgcgcgggaaaacgatctggcctttgactgggagagc
tacacgccgccggtggctcatcgtctgggagtacagacggtggaagccagtatcgagact
ctgcgcaactacatcgactggacgccgttcttcatgacctggtcgctggcgggtaaatat
ccgcgcattctggaagatgaagtggtaggggaagaggcgcagcgcctgttcaaagacgct
aacgagctgctggataagctgagcgcagagaaaaccctgaacccgcgcggcgtggtgggt
ctgttcccggccaaccgcgtgggcgacgatattgaaatctatcgcgatgaaacccgcacc
cacgtgctgacggtgagccatcatctgcgccagcagacggagaaggttggcttcgccaac
tactgcctcgccgattttgtcgcgccgaagctgagcggcaaggcggactacatcggcgcc
ttcgccgtgaccggcggcctggaagaggacgcgctggcggacgcctatgaagcgcagcat
gatgactataacaagatcatgattaaagccatcgccgaccgtctggcggaagccttcgcc
gagtatctgcatgagaaagtgcgtaaggtttactggggctatgcggccaatgagaacctc
agcaatgaggagctgatccgcgaaaattaccaggggatccgcccggcgcccggttatccg
gcctgcccggaacacaccgagaaagcgaccatctgggaactgttggatgtggaagcgcat
accggcatgaagctcaccgagtctttcgccatgtggccaggcgcatcggtttccggctgg
tacttcagccatccggatagcaagtacttcgccgtagcgcagatccagcgcgaccaggtc
gaagattacgcgctgcgtaaaggaatgacgccggcggaggtcgagcgctggttagcgcct
aatctgggctatgatgcggactag
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