KEGG   Klebsiella pneumoniae subsp. pneumoniae KPNIH30: KPNIH30_04050
Entry
KPNIH30_04050     CDS       T03466                                 
Symbol
folA
Name
(GenBank) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
kpw  Klebsiella pneumoniae subsp. pneumoniae KPNIH30
Pathway
kpw00670  One carbon pool by folate
kpw00790  Folate biosynthesis
kpw01100  Metabolic pathways
kpw01240  Biosynthesis of cofactors
kpw04981  Folate transport and metabolism
Module
kpw_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:kpw00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    KPNIH30_04050 (folA)
   00670 One carbon pool by folate
    KPNIH30_04050 (folA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    KPNIH30_04050 (folA)
Enzymes [BR:kpw01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     KPNIH30_04050 (folA)
SSDB
Motif
Pfam: DHFR_1 DUF7466
Other DBs
NCBI-ProteinID: AIX77430
UniProt: A0A2X3GW33
LinkDB
Position
802086..802565
AA seq 159 aa
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRLTWESIGRPLPGRKNI
VISSKPGSDDRVQWVSSVEEAIAACGDVEEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVE
GDTHFPDYDPDEWESVFSEFHDADAQNSHSYCFEILERR
NT seq 480 nt   +upstreamnt  +downstreamnt
atgatcagtctgattgcggcgttagcggtagatcgcgtcattggtatggaaaacgccatg
ccatggaacctgcctgccgatctcgcctggttcaaacgcaacacgttaaataagccggtg
gtgatggggcgtctgacctgggaatccattgggcgcccattgccggggcgtaaaaatatc
gtgatcagcagcaaacccggcagcgacgatcgcgtgcagtgggtctcctccgtagaagaa
gcaattgccgcctgcggcgatgtggaagagattatggtgatcggcggcggccgggtgtat
gagcagttcctgccgaaagcgcagaagctctacttgacccatattgatgcggaagtggaa
ggcgatacccatttcccggattacgatccggacgaatgggagtcggtgttcagcgagttt
catgacgccgacgcgcagaactcccatagctactgctttgagatcctcgaacgccgttaa

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