Klebsiella variicola At-22: Kvar_4264
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Entry
Kvar_4264 CDS
T01170
Name
(GenBank) 2-oxo-acid dehydrogenase E1 subunit, homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
kva
Klebsiella variicola At-22
Pathway
kva00010
Glycolysis / Gluconeogenesis
kva00020
Citrate cycle (TCA cycle)
kva00620
Pyruvate metabolism
kva00785
Lipoic acid metabolism
kva01100
Metabolic pathways
kva01110
Biosynthesis of secondary metabolites
kva01120
Microbial metabolism in diverse environments
kva01200
Carbon metabolism
kva01210
2-Oxocarboxylic acid metabolism
Module
kva_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
kva00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Kvar_4264
00020 Citrate cycle (TCA cycle)
Kvar_4264
00620 Pyruvate metabolism
Kvar_4264
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Kvar_4264
Enzymes [BR:
kva01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Kvar_4264
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
PFO_beta_C
Motif
Other DBs
NCBI-ProteinID:
ADC60141
LinkDB
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Position
complement(4501325..4503988)
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AA seq
887 aa
AA seq
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MSERLPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLSEARKGGVKVAAGASTGGY
VNTIAVEDEPEYPGNLDLERRIRSAIRWNAIMTVLRASKKDLELGGHMASFQSSATFYEV
CFNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTEEQMNNFRQEVHGKGLSSYPH
PKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLKDTSKQTVYAFLGDGEMDEPESK
GAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIINELEGIFAGAGWNVIKVIWGGRWD
ELLRKDTSGKLIQLMEETVDGDYQTFKSKDGAYVREHFFGKYPETAALVADWTDEQIWAL
NRGGHDPKKVYAALKKAQETKGKATVILAHTIKGYGMGDTAEGKNIAHQVKKMNMDGVRY
VRDRFNVPVADADLEKLPYVTFPEGSEEHTYLHAQRQKLHGYLPSRQPNFSEKLELPTLE
DFAPLLEEQNKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYS
PNGQQYTPQDREQVAYYKEDEKGQILQEGINELGAGASWLAAATSYSTNNLPMIPFYIYY
SMFGFQRIGDLCWQAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYD
PSYAYEVAVIMHDGLERMYGEKQENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETI
EGSKGKVQLLGSGSILRHVREAAQILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHP
LETPRVPYIAQVMNDAPAVASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRH
HFEVDASYVVVAALGELAKRGEIDKKVVADAIAKFDIDAEKVNPRLA
NT seq
2664 nt
NT seq
+upstream
nt +downstream
nt
atgtcagaacgtttaccaaatgacgtggatccgatcgaaactcgcgactggctacaggcg
atcgaatcggtcatccgtgaagaaggtgttgagcgtgctcagtatcttattgaccaactc
ctttctgaagcccgcaaaggcggggtgaaagtggctgctggcgcatcgaccggcggttac
gtcaacactattgccgttgaagatgaaccggaatacccgggtaatctggatctggaacgt
cgtatccgttctgcgatccgctggaacgcgatcatgaccgttctgcgcgcatcgaaaaaa
gatctcgaactgggcggccacatggcttccttccagtcttccgcaaccttctacgaagtg
tgcttcaaccacttcttccgcgcacgcaacgagcaggatggcggcgatctggtgtacttc
cagggccacatctctccgggcgtgtatgcgcgtgctttcctggaaggtcgtctgactgaa
gagcagatgaacaatttccgtcaggaagttcacggtaaaggtctgtcctcttatccgcac
ccgaaactgatgccggaattctggcagttcccgaccgtttctatgggtctgggcccaatc
ggggcaatttatcaggctaaattcctgaaatatctggaacaccgtggtctgaaagacacc
tccaaacaaaccgtttatgctttcctgggcgacggtgagatggacgagccggaatctaaa
ggtgcgatcaccatcgccacccgcgagaagctggacaacctggtcttcgttatcaactgt
aacctgcagcgtcttgatggcccggtaacgggtaacggcaaaatcatcaacgaactggaa
ggcatcttcgcgggcgctggctggaacgttatcaaggttatatggggcggtcgttgggat
gagctgctgcgtaaagacaccagcggtaagctgatccagctgatggaagaaaccgttgac
ggcgattaccagaccttcaaatccaaagacggtgcatatgtgcgcgagcacttcttcggt
aaatatccggagaccgcggcgctggttgccgactggactgacgagcagatttgggccctg
aaccgcggcggccacgatccgaagaaagtttacgctgcactgaaaaaagcgcaggaaacc
aaaggcaaagcgaccgtaatcctcgcccataccattaaaggttacggcatgggtgacacc
gctgaaggtaagaacatcgcccaccaggttaagaaaatgaacatggacggcgttcgttac
gtccgcgatcgtttcaacgtgccggttgccgatgccgatctcgaaaaactgccgtacgtc
accttcccggaaggttccgaagagcacacctatctgcacgctcagcgccagaaactgcac
ggctatctgccgagccgtcagccgaacttctctgagaagctggagctgccgacgctggaa
gatttcgctccgctgctggaagagcagaataaagagatctctaccactatcgcatttgtt
cgtgccctgaacgtgatgctgaagaacaaatccatcaaagaccgcctcgtgccgattatc
gccgacgaagcgcgtactttcggtatggaaggtctgttccgtcagatcggtatttacagc
ccgaacggccagcagtacaccccgcaggaccgtgagcaggttgcttactacaaagaagac
gagaaaggccagatcctgcaggaagggatcaacgagctgggcgcaggcgcatcctggctg
gctgcggcgacttcttacagcaccaacaacctgccgatgatcccgttctacatctactac
tcgatgttcgggttccagcgtatcggcgacctgtgctggcaggcaggcgaccagcaggct
cgcggcttcctgatcggtggtacttccggtcgtacaacgctgaacggcgaaggtctgcag
cacgaagatggccacagccatattcagtcgctgactatcccgaactgtatctcttacgat
ccgtcctatgcatacgaagtggcggtcatcatgcatgatggcctggagcgtatgtacggt
gagaaacaagagaacgtttactactacatcactacgctgaacgaaaactaccacatgccg
gccatgccggaaggcgccgaggaaggtatccgtaaaggtatctacaaactcgaaaccatc
gaaggtagcaaaggtaaagttcagctgctgggctccggttctatcctgcgtcacgttcgt
gaagcagcgcagatcctggcgaaagactacggcgtgggctctgacgtgtatagcgtcacc
tccttcaccgaactggcgcgtgatggccaggattgcgaacgctggaacatgctgcacccg
ctggaaaccccgcgcgtgccgtatatcgctcaggtaatgaacgacgctccggccgtggca
tccactgactatatgaaactgttcgctgagcaggttcgtacttacgtaccggctgatgat
taccgcgtactgggtaccgatggcttcggtcgttccgacagccgtgaaaacctgcgtcac
cacttcgaagtcgatgcttcctatgtggtcgttgcagcgctgggcgaactggctaaacgt
ggtgaaatcgataagaaagtggtggctgacgctatcgcgaaattcgacatcgatgcagaa
aaagttaacccgcgtctggcgtaa
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