KEGG   Ketogulonicigenium vulgare WSH-001: KVU_2418
Entry
KVU_2418          CDS       T01909                                 
Symbol
metH
Name
(GenBank) Dihydropteroate synthase, DHPS:Homocysteine S-methyltransferase:Cobalamin-dependent methionine
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
kvl  Ketogulonicigenium vulgare WSH-001
Pathway
kvl00270  Cysteine and methionine metabolism
kvl00450  Selenocompound metabolism
kvl00670  One carbon pool by folate
kvl01100  Metabolic pathways
kvl01110  Biosynthesis of secondary metabolites
kvl01230  Biosynthesis of amino acids
kvl04980  Cobalamin transport and metabolism
kvl04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:kvl00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    KVU_2418 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    KVU_2418 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    KVU_2418 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    KVU_2418 (metH)
   04980 Cobalamin transport and metabolism
    KVU_2418 (metH)
Enzymes [BR:kvl01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     KVU_2418 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding DUF1129
Other DBs
NCBI-ProteinID: AEM42256
UniProt: F9Y766
LinkDB
Position
2565025..2568753
AA seq 1242 aa
MTALPKSASFARIVDAARQRILVLDGAMGTQIQLLKMGEDEYLGHGSAGCQCHIHSDHPQ
KGNNDLLNLTQPEAIEEIHFRYAMAGADIVETNTFSSTTIAQADYALEDQVHALNVQGAR
LARSGVDRATAIDGRMRFVAGAVGPTNRTASISPDVNDPGFRAVSFDDLRIAYAQQIRGL
IEGGVDLILIETIFDTLNAKAAIFAAEEVFIEIGERLPVMISGTITDLSGRTLSGQTPTA
FWHSVRHAGPFTIGLNCALGANAMRAHLAEISAIADTFVCVYPNAGLPNAMGDYDETPAF
TAQQIEGFARDGLVNIVGGCCGTSPEHIRAMAEAVAKYRPRAIPEHAPLMRLSGLEPFIL
TPEIPFVNVGERTNVTGSAKFRKMITAGDFASALQVARDQVENGAQIIDINMDEGLIDSQ
AAMVKFLNLVASEPDIARVPVMIDSSKWDVIEAGLKCVQGKAIVNSISMKEGEAAFLHHA
RLCRAYGAAVVVMAFDETGQADTEDRKVEICSRAYKLLTEEVGFPPEDIIFDPNVFAVAT
GIEEHNNYGVDFINATRRIMEACPHVHISGGISNLSFSFRGNEPVREAMHAVFLYHAIQV
GMDMGIVNAGQLAVYDQIDPELREACEDVVLNRRDDATERLLDLAERYRGQGGAEKKERD
LAWRDWDVAKRLEHALVNGITEFIEGDTEEARLAAQRPLHVIEGPLMDGMNVVGDLFGAG
KMFLPQVVKSARVMKQAVAVLLPYLEEEKAAGGGVGRQSAGKILMATVKGDVHDIGKNIV
GVVLACNNYDIIDLGVMVSSEKILAAAREHDVDAIGLSGLITPSLDEMVHVAAEMERQGF
DIPLLIGGATTSRVHTAVKIAPAYQRGQVVYSVDASRAVGVAQNLLGSRSLAYQAEVRAE
YEKVAEGYLRGEREKQRLPLADARANPVKIDWAAYQAKVPSFLGTKVYDDWDLADLAQYI
DWTPFFQSWELKGVYPRILQDEKYGETARSLFADAQAMLQQIIDEKWFDPRAVVGFWPAN
AVGDDIVLFADETRSHILATMHTLRQQLPRRDGRPNIAMSDFVAPMGQAEYIGGFVVTAG
FKELEIAARFEAANDDYNAIMVKALADRFAEAFAERMHQHVRRELWAYAADEVLPNDALI
REEYAGIRPAPGYPAQPDHTEKLTLFRLLDAEAATGVKLTESMAMWPGSTVSGLYIAHPE
SYYFGVAKVEEDQVADYAARKGMDKAEAERWLAPILNYIPKA
NT seq 3729 nt   +upstreamnt  +downstreamnt
atgaccgcgctacccaaatccgcaagtttcgcccgcattgttgatgctgcgcgtcagcgc
attctggtgctggatggcgcgatgggcacgcagatccagctgctgaaaatgggcgaggat
gaatatctgggccatggcagcgcgggttgccaatgtcatattcattccgaccatccgcaa
aagggcaataacgacctgctcaacctgacccagcccgaggcgatcgaggaaatccatttc
cgctatgccatggccggggccgatattgtcgagacgaataccttttcctcgaccaccatc
gcgcaggcggattacgcattagaggatcaggtccatgccctgaacgttcagggcgcgcgg
ctggcccgcagcggtgtcgaccgcgccaccgccatcgacggacggatgcgttttgtcgcc
ggggcggtggggccgacgaaccgcacggcctcgatcagccctgacgtgaacgaccccggc
tttcgcgccgtcagctttgacgatctgcgcatcgcctatgcccagcagatccgcggcctg
atcgaaggcggcgtcgatctgatcttgatcgagacgatctttgacacgctgaacgccaaa
gccgcgattttcgccgccgaggaggtgttcattgaaattggcgagcggctgccggtgatg
atctcgggcacaatcactgacctgtcgggccgcacgctgtcgggtcaaacgccgaccgcc
ttttggcattcggtgcgccacgcgggtccctttaccatcgggctgaactgcgcattgggc
gcgaatgccatgcgcgcgcatctggccgagatttccgccatcgccgatacattcgtttgc
gtctacccgaacgcgggtcttcccaatgccatgggcgattacgatgagacccccgccttc
accgcccagcagatcgagggatttgcccgcgacggtctggtgaatatcgtcggcggttgc
tgcggcacttcgcccgagcatatccgcgccatggccgaggcggtcgccaaataccgaccc
cgcgccatccccgaacatgcgccgctgatgcgcctgtcggggctcgagccgtttattctg
acgcccgagattcctttcgtgaacgtgggcgagcgcacgaatgtcacggggtccgccaag
ttccgcaagatgatcacggcgggcgatttcgccagcgccctgcaggtcgcgcgtgatcag
gtggaaaacggcgcgcagatcatcgacatcaatatggacgagggtctgatcgacagccag
gccgcgatggtgaaattcctgaaccttgtcgcctcggaacccgatatcgcccgcgtgccg
gtgatgatcgacagttccaaatgggatgtgatcgaggcgggcctgaaatgcgtgcagggc
aaggcaatcgtcaactcgatctcgatgaaagagggcgaggctgcgtttttgcaccatgcg
cgcctgtgccgggcctatggcgccgccgtggtcgtgatggcctttgacgagacgggccag
gcggataccgaggatcgcaaggtcgagatttgcagccgcgcctataagctgctgaccgag
gaggtcggctttccgcccgaagatatcatctttgaccccaacgtctttgccgtcgccacg
gggatcgaggaacacaataattacggcgtcgatttcatcaacgccacgcgccgcatcatg
gaagcctgtccgcatgtccatatttcgggcgggatttccaacctgtccttcagcttccgc
ggcaatgaacccgtgcgcgaggcgatgcatgccgttttcctctatcacgccattcaagtc
ggcatggatatgggcatcgtcaatgcggggcagcttgccgtctacgaccagatcgatccg
gaactgcgcgaggcctgcgaggatgtcgttctgaatcgccgcgacgatgcgaccgagcgt
ttgttggatctggccgagcggtatcgcggccaaggcggcgcggagaagaaagagcgtgat
ctggcgtggcgcgactgggatgtggcgaaacgcttggaacatgcgctggtgaacggcatc
accgagtttatcgagggcgacaccgaggaagcccgccttgccgcccagcgtccgctgcat
gtgatcgaagggccgttgatggacggcatgaacgtcgtcggcgatttgttcggcgcaggt
aaaatgttcctgccgcaggtggtgaaatccgcccgcgtgatgaaacaggccgtcgccgtg
ctgctgccctatctggaagaggaaaaggcagcgggcggcggtgtgggccgtcaaagcgcc
ggtaaaatcctgatggcgacggtaaagggcgatgtgcatgacatcggcaagaacatcgtc
ggcgtcgtgctggcgtgcaacaattacgacatcatcgaccttggggtcatggtgtcatcc
gagaaaatcctggctgccgcgcgcgaacatgatgtcgatgcgattggcctgtcggggctg
atcacgccgtccttggacgagatggtgcatgtcgcggccgagatggagcgccaaggcttt
gacattccactgctgatcggcggggcgacgaccagccgcgtgcatacggcggtgaaaatt
gcgccagcctaccagcgcgggcaggtggtctattccgtcgacgccagccgcgcggtgggg
gttgcgcagaacctgcttggctcgcgcagcctggcctatcaagccgaggtgcgcgccgaa
tatgagaaggtggccgagggttacttgcgcggtgagcgcgagaaacagcgcctgccgctg
gccgacgcgcgtgccaatccggtcaagatcgactgggccgcctatcaggcaaaggtgccc
agctttcttggcaccaaggtctatgacgattgggatctggctgatcttgcgcaatacatc
gattggacacccttcttccaaagctgggagttgaagggcgtctatccccgcatcttgcag
gacgagaaatacggcgagaccgcgcggtcgctgtttgcggatgcgcaggccatgttgcag
cagatcattgatgaaaaatggttcgacccgcgcgccgtcgtcggcttttggcccgccaat
gcggtgggcgatgatatcgtgttattcgccgatgagactcgcagccatattctggccacg
atgcatacgctgcgccagcaactgccgcgccgcgatgggcgccccaatatcgccatgtcc
gatttcgtcgccccgatggggcaggcggaatatatcggcggctttgtcgttactgcgggt
ttcaaagaactcgagatcgccgcgcggttcgaggcggcgaacgacgattacaatgccatc
atggtcaaagccctcgccgaccgctttgccgaagcctttgccgagcggatgcaccagcat
gtccggcgcgaactatgggcctatgccgccgacgaggtgctgcccaatgatgcccttatc
cgcgaggaatatgccggtatccgtcccgcaccgggctatcctgcccagcccgatcatacc
gaaaagctgaccctgttccgcctgctggatgccgaggctgcgacgggcgtcaagctgacc
gaaagcatggcgatgtggccgggctcgaccgtatcgggcctttatatcgcgcatcccgaa
agctattatttcggggtggccaaggtcgaggaagatcaggttgccgattatgccgcgcgc
aagggcatggataaggccgaggccgagcgctggctggccccgatcctgaattatatccca
aaggcttaa

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