Ketogulonicigenium vulgare WSH-001: KVU_2418
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Entry
KVU_2418 CDS
T01909
Symbol
metH
Name
(GenBank) Dihydropteroate synthase, DHPS:Homocysteine S-methyltransferase:Cobalamin-dependent methionine
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
kvl
Ketogulonicigenium vulgare WSH-001
Pathway
kvl00270
Cysteine and methionine metabolism
kvl00450
Selenocompound metabolism
kvl00670
One carbon pool by folate
kvl01100
Metabolic pathways
kvl01110
Biosynthesis of secondary metabolites
kvl01230
Biosynthesis of amino acids
kvl04980
Cobalamin transport and metabolism
kvl04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
kvl00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
KVU_2418 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
KVU_2418 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
KVU_2418 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
KVU_2418 (metH)
04980 Cobalamin transport and metabolism
KVU_2418 (metH)
Enzymes [BR:
kvl01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
KVU_2418 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
DUF1129
Motif
Other DBs
NCBI-ProteinID:
AEM42256
UniProt:
F9Y766
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All DBs
Position
2565025..2568753
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AA seq
1242 aa
AA seq
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MTALPKSASFARIVDAARQRILVLDGAMGTQIQLLKMGEDEYLGHGSAGCQCHIHSDHPQ
KGNNDLLNLTQPEAIEEIHFRYAMAGADIVETNTFSSTTIAQADYALEDQVHALNVQGAR
LARSGVDRATAIDGRMRFVAGAVGPTNRTASISPDVNDPGFRAVSFDDLRIAYAQQIRGL
IEGGVDLILIETIFDTLNAKAAIFAAEEVFIEIGERLPVMISGTITDLSGRTLSGQTPTA
FWHSVRHAGPFTIGLNCALGANAMRAHLAEISAIADTFVCVYPNAGLPNAMGDYDETPAF
TAQQIEGFARDGLVNIVGGCCGTSPEHIRAMAEAVAKYRPRAIPEHAPLMRLSGLEPFIL
TPEIPFVNVGERTNVTGSAKFRKMITAGDFASALQVARDQVENGAQIIDINMDEGLIDSQ
AAMVKFLNLVASEPDIARVPVMIDSSKWDVIEAGLKCVQGKAIVNSISMKEGEAAFLHHA
RLCRAYGAAVVVMAFDETGQADTEDRKVEICSRAYKLLTEEVGFPPEDIIFDPNVFAVAT
GIEEHNNYGVDFINATRRIMEACPHVHISGGISNLSFSFRGNEPVREAMHAVFLYHAIQV
GMDMGIVNAGQLAVYDQIDPELREACEDVVLNRRDDATERLLDLAERYRGQGGAEKKERD
LAWRDWDVAKRLEHALVNGITEFIEGDTEEARLAAQRPLHVIEGPLMDGMNVVGDLFGAG
KMFLPQVVKSARVMKQAVAVLLPYLEEEKAAGGGVGRQSAGKILMATVKGDVHDIGKNIV
GVVLACNNYDIIDLGVMVSSEKILAAAREHDVDAIGLSGLITPSLDEMVHVAAEMERQGF
DIPLLIGGATTSRVHTAVKIAPAYQRGQVVYSVDASRAVGVAQNLLGSRSLAYQAEVRAE
YEKVAEGYLRGEREKQRLPLADARANPVKIDWAAYQAKVPSFLGTKVYDDWDLADLAQYI
DWTPFFQSWELKGVYPRILQDEKYGETARSLFADAQAMLQQIIDEKWFDPRAVVGFWPAN
AVGDDIVLFADETRSHILATMHTLRQQLPRRDGRPNIAMSDFVAPMGQAEYIGGFVVTAG
FKELEIAARFEAANDDYNAIMVKALADRFAEAFAERMHQHVRRELWAYAADEVLPNDALI
REEYAGIRPAPGYPAQPDHTEKLTLFRLLDAEAATGVKLTESMAMWPGSTVSGLYIAHPE
SYYFGVAKVEEDQVADYAARKGMDKAEAERWLAPILNYIPKA
NT seq
3729 nt
NT seq
+upstream
nt +downstream
nt
atgaccgcgctacccaaatccgcaagtttcgcccgcattgttgatgctgcgcgtcagcgc
attctggtgctggatggcgcgatgggcacgcagatccagctgctgaaaatgggcgaggat
gaatatctgggccatggcagcgcgggttgccaatgtcatattcattccgaccatccgcaa
aagggcaataacgacctgctcaacctgacccagcccgaggcgatcgaggaaatccatttc
cgctatgccatggccggggccgatattgtcgagacgaataccttttcctcgaccaccatc
gcgcaggcggattacgcattagaggatcaggtccatgccctgaacgttcagggcgcgcgg
ctggcccgcagcggtgtcgaccgcgccaccgccatcgacggacggatgcgttttgtcgcc
ggggcggtggggccgacgaaccgcacggcctcgatcagccctgacgtgaacgaccccggc
tttcgcgccgtcagctttgacgatctgcgcatcgcctatgcccagcagatccgcggcctg
atcgaaggcggcgtcgatctgatcttgatcgagacgatctttgacacgctgaacgccaaa
gccgcgattttcgccgccgaggaggtgttcattgaaattggcgagcggctgccggtgatg
atctcgggcacaatcactgacctgtcgggccgcacgctgtcgggtcaaacgccgaccgcc
ttttggcattcggtgcgccacgcgggtccctttaccatcgggctgaactgcgcattgggc
gcgaatgccatgcgcgcgcatctggccgagatttccgccatcgccgatacattcgtttgc
gtctacccgaacgcgggtcttcccaatgccatgggcgattacgatgagacccccgccttc
accgcccagcagatcgagggatttgcccgcgacggtctggtgaatatcgtcggcggttgc
tgcggcacttcgcccgagcatatccgcgccatggccgaggcggtcgccaaataccgaccc
cgcgccatccccgaacatgcgccgctgatgcgcctgtcggggctcgagccgtttattctg
acgcccgagattcctttcgtgaacgtgggcgagcgcacgaatgtcacggggtccgccaag
ttccgcaagatgatcacggcgggcgatttcgccagcgccctgcaggtcgcgcgtgatcag
gtggaaaacggcgcgcagatcatcgacatcaatatggacgagggtctgatcgacagccag
gccgcgatggtgaaattcctgaaccttgtcgcctcggaacccgatatcgcccgcgtgccg
gtgatgatcgacagttccaaatgggatgtgatcgaggcgggcctgaaatgcgtgcagggc
aaggcaatcgtcaactcgatctcgatgaaagagggcgaggctgcgtttttgcaccatgcg
cgcctgtgccgggcctatggcgccgccgtggtcgtgatggcctttgacgagacgggccag
gcggataccgaggatcgcaaggtcgagatttgcagccgcgcctataagctgctgaccgag
gaggtcggctttccgcccgaagatatcatctttgaccccaacgtctttgccgtcgccacg
gggatcgaggaacacaataattacggcgtcgatttcatcaacgccacgcgccgcatcatg
gaagcctgtccgcatgtccatatttcgggcgggatttccaacctgtccttcagcttccgc
ggcaatgaacccgtgcgcgaggcgatgcatgccgttttcctctatcacgccattcaagtc
ggcatggatatgggcatcgtcaatgcggggcagcttgccgtctacgaccagatcgatccg
gaactgcgcgaggcctgcgaggatgtcgttctgaatcgccgcgacgatgcgaccgagcgt
ttgttggatctggccgagcggtatcgcggccaaggcggcgcggagaagaaagagcgtgat
ctggcgtggcgcgactgggatgtggcgaaacgcttggaacatgcgctggtgaacggcatc
accgagtttatcgagggcgacaccgaggaagcccgccttgccgcccagcgtccgctgcat
gtgatcgaagggccgttgatggacggcatgaacgtcgtcggcgatttgttcggcgcaggt
aaaatgttcctgccgcaggtggtgaaatccgcccgcgtgatgaaacaggccgtcgccgtg
ctgctgccctatctggaagaggaaaaggcagcgggcggcggtgtgggccgtcaaagcgcc
ggtaaaatcctgatggcgacggtaaagggcgatgtgcatgacatcggcaagaacatcgtc
ggcgtcgtgctggcgtgcaacaattacgacatcatcgaccttggggtcatggtgtcatcc
gagaaaatcctggctgccgcgcgcgaacatgatgtcgatgcgattggcctgtcggggctg
atcacgccgtccttggacgagatggtgcatgtcgcggccgagatggagcgccaaggcttt
gacattccactgctgatcggcggggcgacgaccagccgcgtgcatacggcggtgaaaatt
gcgccagcctaccagcgcgggcaggtggtctattccgtcgacgccagccgcgcggtgggg
gttgcgcagaacctgcttggctcgcgcagcctggcctatcaagccgaggtgcgcgccgaa
tatgagaaggtggccgagggttacttgcgcggtgagcgcgagaaacagcgcctgccgctg
gccgacgcgcgtgccaatccggtcaagatcgactgggccgcctatcaggcaaaggtgccc
agctttcttggcaccaaggtctatgacgattgggatctggctgatcttgcgcaatacatc
gattggacacccttcttccaaagctgggagttgaagggcgtctatccccgcatcttgcag
gacgagaaatacggcgagaccgcgcggtcgctgtttgcggatgcgcaggccatgttgcag
cagatcattgatgaaaaatggttcgacccgcgcgccgtcgtcggcttttggcccgccaat
gcggtgggcgatgatatcgtgttattcgccgatgagactcgcagccatattctggccacg
atgcatacgctgcgccagcaactgccgcgccgcgatgggcgccccaatatcgccatgtcc
gatttcgtcgccccgatggggcaggcggaatatatcggcggctttgtcgttactgcgggt
ttcaaagaactcgagatcgccgcgcggttcgaggcggcgaacgacgattacaatgccatc
atggtcaaagccctcgccgaccgctttgccgaagcctttgccgagcggatgcaccagcat
gtccggcgcgaactatgggcctatgccgccgacgaggtgctgcccaatgatgcccttatc
cgcgaggaatatgccggtatccgtcccgcaccgggctatcctgcccagcccgatcatacc
gaaaagctgaccctgttccgcctgctggatgccgaggctgcgacgggcgtcaagctgacc
gaaagcatggcgatgtggccgggctcgaccgtatcgggcctttatatcgcgcatcccgaa
agctattatttcggggtggccaaggtcgaggaagatcaggttgccgattatgccgcgcgc
aagggcatggataaggccgaggccgagcgctggctggccccgatcctgaattatatccca
aaggcttaa
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