Lactobacillus acidophilus NCFM: LBA0628
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Entry
LBA0628 CDS
T00231
Symbol
hmcS
Name
(GenBank) hydroxymethylglutaryl-CoA synthase
KO
K01641
hydroxymethylglutaryl-CoA synthase [EC:
2.3.3.10
]
Organism
lac
Lactobacillus acidophilus NCFM
Pathway
lac00280
Valine, leucine and isoleucine degradation
lac00650
Butanoate metabolism
lac00900
Terpenoid backbone biosynthesis
lac01100
Metabolic pathways
lac01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
lac00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
LBA0628 (hmcS)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
LBA0628 (hmcS)
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
LBA0628 (hmcS)
Enzymes [BR:
lac01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.10 hydroxymethylglutaryl-CoA synthase
LBA0628 (hmcS)
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Gene cluster
GFIT
Motif
Pfam:
HMG_CoA_synt_C
HMG_CoA_synt_N
ACP_syn_III_C
ACP_syn_III
Chal_sti_synt_N
FAE1_CUT1_RppA
Peptidase_M4
Motif
Other DBs
NCBI-ProteinID:
AAV42507
UniProt:
Q5FLB7
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All DBs
Position
614586..615749
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AA seq
387 aa
AA seq
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MQVGIDKIGLFTPNKYVDMVDLAHARNQDPNKFLIGIGQSEMSVADQTQDAVSMGINATM
KYIDRIDKDKVGLLVLGTESGIDQSKSASLFVKTALKLKPEVRTFEVKEACFGLTAAVMI
ARDFVRVHPDQTAIVIGSDIARYGVNTGGEVTQGAGSVSMLIKADPKILALNDGHSAYSE
DINDFWRPNASRVAMVDGKYSTQVYLDFFKKTFNDYKKQKNLETSAFDAIVYHLPFTKMG
LKANRIAVEDQDQAVTENLETSFEASKQLSRRVGNIYTASLYMSLLSLLENGNLAAGSLI
GLFSYGSGAMGEFYSGSLVEGYEKEIDQIKDQAMLDHRKKLTISEYEDVFNTALEDPEDG
VVLESDDKEGTWYFAGTQGHVRQYKVK
NT seq
1164 nt
NT seq
+upstream
nt +downstream
nt
atgcaagtaggaattgataagattggactttttacaccaaataaatatgtagatatggtg
gacctagcacatgctagaaatcaagatcccaataagtttttaattgggattggtcaaagt
gaaatgagtgtagccgatcaaactcaagacgcagtttcaatgggaattaacgctacaatg
aaatatattgaccgcattgataaagataaggttgggttgctcgttttaggtacagaaagt
ggaatcgatcaatcaaaatctgcgtcattatttgtaaaaactgctttaaaattaaagcct
gaagttagaacttttgaagttaaggaagcttgctttgggctaactgcggctgtaatgatt
gctagagactttgttagagttcatcctgatcaaactgcaattgtaattggtagtgatatt
gcacgttatggtgttaatactgggggcgaagtaacgcaaggcgctggtagtgtaagtatg
ttaattaaggcagatccaaagatccttgctttaaatgatggtcatagtgcatatagtgaa
gatattaatgatttctggcgtcccaatgcttctcgtgttgctatggttgatggtaaatat
tccactcaagtatatttagacttctttaagaagactttcaatgattacaagaagcaaaaa
aacttagaaactagtgcttttgatgccattgtttaccatttgccgtttactaagatggga
cttaaggcaaatagaattgcagttgaggatcaagatcaagctgtaacagaaaacttagaa
actagttttgaagcttctaagcaattgtctcgtcgtgtaggtaatatttatactgcttct
ttatacatgagcttacttagtttattagaaaatggtaatttagcagcaggatcattaata
ggtttattctcttatggttcaggggctatgggtgaattttacagcggtagtttagttgaa
ggctatgaaaaagaaatagatcaaattaaggatcaagcaatgcttgatcaccgtaagaag
ttaactatttcagagtatgaagatgtcttcaatactgcattagaagatccagaagatggt
gtagtactggaaagtgatgataaagaaggtacttggtattttgccggtacgcaaggccat
gttcgtcaatacaaagttaaataa
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