KEGG   Leptospira tipperaryensis: A0128_20705
Entry
A0128_20705       CDS       T04558                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
laj  Leptospira tipperaryensis
Pathway
laj00270  Cysteine and methionine metabolism
laj00450  Selenocompound metabolism
laj00670  One carbon pool by folate
laj01100  Metabolic pathways
laj01110  Biosynthesis of secondary metabolites
laj01230  Biosynthesis of amino acids
laj04980  Cobalamin transport and metabolism
laj04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:laj00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    A0128_20705 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    A0128_20705 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    A0128_20705 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    A0128_20705 (metH)
   04980 Cobalamin transport and metabolism
    A0128_20705 (metH)
Enzymes [BR:laj01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     A0128_20705 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding OKR_DC_1_N
Other DBs
NCBI-ProteinID: AOP36435
UniProt: A0A1D7V3M8
LinkDB
Position
2:274289..278029
AA seq 1246 aa
MTQKAQNYTNPKAKELLSLLEKQILVIDGAMGTMIQRFPLTEDDFRGEVLKNHSSPLKGN
NELLCLTRPDVIEAIHVKFLEAGANILETNTFSSNQVSQGDYKTEFLVADLNKAAVKCAR
NAIEKFQKTNPSHPCFLAGAIGPTTRTATLSPDVNNPAFRAVTFDDLVATFYEQVRALVE
AGVDLLLPETNIDTLNLKAAIYAIEQVFEDLQVRIPVCLSVTITDASGRTLSGQTVEAFY
NSIAHCKPLSVGINCALGADEMRPYIEELSRVSSCMISCYPNAGLPNAFGGYDQTPEEFG
KYIQEFASSGWLNIAGGCCGTTPEHIAAAAKAVQGKKPRTLPQIPEVTRLSGLEPLNITP
DKGFLLIGERTNVTGSPRFKKLIIEGNFEEAVSVALQQVEAGANIIDINFDEALLDGEAS
MRHFLNLIAGEPDIAKVPFMVDSSKWTVLEEGLKCIQGKPIVNSISLKEGEDKFLEHARK
IQRYGAAAIVMAFDEQGQAATKDEKVRICKRAYDLLVTKADFNPVDIIFDPNILTVATGI
EEHNNYAMDFIEAIREIKKLCPGAKVSGGLSNVSFSFRGNNPVREAMHSVFLYYAIQAGM
DMAIVNAGMLAVYEEIPKDLLEYVEDVILNRRPDATERLVEFAENVKSGDKAEKKEETWR
EGTSVEERLSHALVKGIVEYIDQDTEEARLKYGRPLTVIEGPLMDGMKIVGELFGAGKMF
LPQVVKSARVMKKSVAYLLPFMEEEKKNNQDTSSRPKFLIATVKGDVHDIGKNIVGVVLA
CNNYEVIDLGVMVPADKILEEARKINASIIGLSGLITPSLDEMVHVASEMKRTGFNVPLL
IGGATTSSAHTAVKIAPAYDQPVVHVVDASRVVNVVNQLLHPDLNEAYSKKIKEDQLAAR
ENYFSTRAERKLISLDQARENKEIIDWSTTPIDKPALTGVKVFDQEISLETLIPFIDWTP
FFTAWELKGRYPAILESETTGKQARELFADAQKLMKTITDGKLFKTKGVIGIFPANSVGD
DIEVYEDESRSKLLTVFHTLRQQIQKEDATEPNYCLADYVAPKESGRIDYIGGFAVTAGH
GVEEFAKEFEKNLDDYNSIMSKALGDRFAEAFAEYMHYKVRKEYWGYDKDENLAPEDLIR
ERYRGIRPAAGYPASPDHTEKRVLFDLLQAEKNTGITLTEHFAMWPASSVSGLYFAHPQS
KYFAVAKISRDQIEEYAKRKGMTIEETERWLAPNLAYDPLAVSIAR
NT seq 3741 nt   +upstreamnt  +downstreamnt
atgactcagaaagctcagaactacacaaatccaaaagcaaaagaacttctctcccttctc
gaaaaacaaatcttagtaatcgacggagcgatgggaacgatgatccaaagattccctttg
actgaagacgatttcagaggagaggttttaaaaaatcattcttctcccttaaaaggaaac
aacgaactcctctgccttacacgtccggacgtaatcgaagcgattcacgtaaaatttttg
gaagcgggggcaaacatccttgagacaaacacctttagttccaaccaagtttctcagggc
gactataaaaccgaattcttagtcgcagatctaaacaaggccgcggtcaaatgcgcgcgt
aacgcgatcgaaaaatttcaaaagacgaatccaagtcatccttgttttttagcgggagcg
atcggaccgacgactcgaacagcaacgttgtctccggatgtaaacaatcccgcatttaga
gcggtaacgtttgacgatttagtagccaccttttacgaacaagtaagagccctcgtggaa
gcaggggtcgaccttcttcttcccgaaacaaatatcgacaccctcaatttaaaggccgcc
atctacgcgatcgaacaagtctttgaagaccttcaagttcgaatcccggtttgtctctca
gtgacgatcacggatgcttcgggaagaactctttccggacaaacggtggaagcgttttac
aattccatcgctcattgcaaacctctttccgtcggaatcaactgcgcgcttggcgctgac
gagatgagaccttatatcgaagaactctccagagtttcttcctgtatgattagttgttat
ccaaacgcaggccttcccaacgcgttcggaggatacgatcaaactccggaagaattcgga
aaatacattcaagaatttgcaagttcaggttggttgaatatagcaggcggctgttgtgga
acaacacccgaacacatcgctgcggccgcaaaagcggttcaaggaaaaaaaccgagaact
cttcctcaaattccggaagtgacaagactttccggactcgaacctttgaacatcactccg
gacaagggattcttactcataggagaaagaacgaacgtaaccggatctcctcgttttaaa
aaactcatcatcgaaggcaattttgaagaagcggtttcagtcgctttacaacaagtggaa
gccggagccaatattatcgatattaacttcgacgaagccttgttagacggggaagcttcg
atgaggcatttcttaaatctcatcgcgggagaaccggatatcgcaaaagttccgtttatg
gtggattcctccaaatggaccgttttagaagaaggcctaaaatgtatccaaggaaagccg
attgtgaactcgatctctctgaaagaaggagaggacaaattcttagaacacgcgcggaaa
atccagagatacggcgcggccgcgatcgttatggcctttgacgaacaaggtcaagccgcg
accaaagacgaaaaagttcgtatttgcaaacgagcatacgatcttctcgtaaccaaggcg
gattttaatcccgtagatatcatctttgatccgaatattctcacggtagcaaccgggatc
gaagaacataacaactatgcgatggactttatcgaagccatccgagaaatcaaaaaactc
tgtccgggcgcgaaagtctccggcggtttatctaacgtgtctttttctttccgaggaaac
aatccggtaagagaagcgatgcactccgtattcttatattacgcgatccaagcgggtatg
gacatggcgatcgtaaacgcagggatgctcgccgtttacgaagaaattccaaaggatctt
ttagaatacgtggaagacgtaatcttaaatagaagaccggatgcgactgaacgtcttgtg
gaatttgcggaaaacgtaaaatccggagataaggccgagaaaaaagaagagacttggaga
gaagggacttcagttgaagaaaggctttctcacgctcttgtaaaaggaatcgtagaatac
atcgatcaagatacggaagaagcgcgtctcaaatacggacgtccgttaaccgtcatcgaa
ggccctctcatggatggaatgaagatcgtgggagaacttttcggcgcgggaaaaatgttt
cttcctcaagttgttaagagcgcacgtgtaatgaaaaaatctgtggcctatcttttaccg
tttatggaagaggagaagaaaaacaatcaagacacttcttctcgtccgaaattcttaatc
gcaacggtcaaaggagacgttcatgatatcggaaagaatatcgtgggtgtggtccttgct
tgtaacaactacgaagtgatagacttaggggtgatggttcccgctgataaaattttagag
gaagcaagaaagatcaacgcgagtatcatcggcctttccgggcttatcacgccttctttg
gatgagatggttcacgtagcctccgaaatgaaacgaaccggattcaacgttcctcttttg
atcggaggagctactacaagctccgcgcataccgcggtaaaaatcgcacccgcatacgat
caacccgtggttcacgttgtagacgcgtcgagggtcgtaaacgtagtcaatcaacttctt
catcctgatcttaacgaagcgtattctaaaaagatcaaggaagatcaactcgcagcgaga
gagaattattttagtacaagagcggagagaaaacttatctccctcgatcaagcgagagaa
aacaaagaaataatcgattggtctacgactccgatcgacaaacccgcgttaaccggcgta
aaagtttttgatcaggaaatttctttggaaactctgattccttttatcgactggacccca
ttcttcaccgcttgggaattgaaaggaagatatcccgcgattcttgaaagtgaaacaacg
gggaaacaagccagggaacttttcgcagacgctcagaaactcatgaagaccatcaccgac
ggaaaacttttcaaaaccaagggtgtgatcggaatctttccggctaacagcgtaggtgac
gatatcgaagtctacgaagacgaatctcgttccaaattgctcacagtttttcatacgctg
cggcagcaaattcaaaaagaagacgcaacggaacctaattactgtttggcggattacgta
gcgccgaaagaatccggaagaatcgattatatcggtggatttgcggtaacggccggacac
ggagtggaagaattcgcaaaagaattcgagaagaatctcgacgactataattccatcatg
tcgaaggcgttaggcgatcgtttcgcagaggcgttcgcggaatacatgcactacaaggtt
cgaaaagaatattggggttatgacaaagacgaaaatctcgcaccggaagatctgattcga
gaacgttacagaggaattcgtccggccgccggatatcctgcgtctccggatcataccgaa
aagagagttctctttgatcttctccaagccgaaaaaaatacggggatcacgcttacggaa
cactttgcgatgtggcctgcgagttcggtaagtggattgtattttgcacatcctcaatcg
aaatacttcgcggtcgcaaaaatcagccgcgaccaaatcgaggaatacgcaaaacgcaaa
ggaatgacgatcgaagaaacagaacgttggttggctccgaatctcgcctatgatccgctt
gcggtttcgatcgcgagataa

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