Lagenorhynchus albirostris (white-beaked dolphin): 132512024
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Entry
132512024 CDS
T10760
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein isoform X1
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
lalb Lagenorhynchus albirostris (white-beaked dolphin)
Pathway
lalb01524
Platinum drug resistance
lalb03440
Homologous recombination
lalb03460
Fanconi anemia pathway
lalb04120
Ubiquitin mediated proteolysis
lalb04151
PI3K-Akt signaling pathway
lalb05206
MicroRNAs in cancer
lalb05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
lalb00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
132512024 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
132512024 (BRCA1)
03460 Fanconi anemia pathway
132512024 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
132512024 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
132512024 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
132512024 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
132512024 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
lalb01009
]
132512024 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
lalb04121
]
132512024 (BRCA1)
03036 Chromosome and associated proteins [BR:
lalb03036
]
132512024 (BRCA1)
03400 DNA repair and recombination proteins [BR:
lalb03400
]
132512024 (BRCA1)
Enzymes [BR:
lalb01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
132512024 (BRCA1)
Protein phosphatases and associated proteins [BR:
lalb01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
132512024 (BRCA1)
Ubiquitin system [BR:
lalb04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
132512024 (BRCA1)
Multi subunit type E3
BRCC complex
132512024 (BRCA1)
Chromosome and associated proteins [BR:
lalb03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
132512024 (BRCA1)
DNA repair and recombination proteins [BR:
lalb03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
132512024 (BRCA1)
BRCA1-A complex
132512024 (BRCA1)
BRCA1-B complex
132512024 (BRCA1)
BRCA1-C complex
132512024 (BRCA1)
BRCA complex
132512024 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
132512024 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
zf-C3HC4_2
zf-RING_UBOX
zf-C3HC4_4
zf-RING_2
zf-C3HC4_3
zf-RING_5
RING_XB3-XBAT31
zf-RING_6
BRCT_2
zf-ANAPC11
zf-Nse
zf-rbx1
Baculo_IE-1
zf-RING_10
Motif
Other DBs
NCBI-GeneID:
132512024
NCBI-ProteinID:
XP_059991975
LinkDB
All DBs
Position
20:complement(41399080..41462221)
Genome browser
AA seq
1907 aa
AA seq
DB search
MDFSANHVEEVQNVLNAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
CPLCKNHITKRSLQESTRFSQLVEELLKIIHAFELDTGLQIANSYNFSKKESNSSEHLKE
EVSIIQSMGYRNRAKKLQQSEPENPTLETSLSVQLSNLGIVRSLRTKQQIQPQNKSVYIE
LGSDSSEDTVNKASYFSVGDHELLEITPQGAKAEASLNRAKKAACEFSEKDITKAEHHQF
SNKDLTTTEKHETEKHPEKYQGIFVSNLHVEPCGTDTHASSLQHENSSLLLTKDRMNVEK
AEFCNKSKQLVLGKSHQSRWAESKDTCNDRQTPSTEKKVVLNADPLYGRKELNKQKPASS
DSPRDSQEFPWITLNSSIQRVNEWFSRSDEMLTSYDSRDGAFESNTEVARAVEVPKEVDG
YLGSSEKIDLMTSDPHGALIHERVHSKPVESNIEDKIFGKTYQRKTSLPNLSRIAEDLII
GASTVEPQITQERPLTKKLRRKRRSTSGLHPEDFIKKVDLAVLPKTPEKIIEGTDQTEQN
GHGINITSNGHETEMKGGYVQKEKNANLTESLEKESAFRTKAEPISSSISNMELELNIHS
SKAPKNRLRRKSSTRNIHALELAVSRNPSPPNHTELQIDSCSSSEEMKKKHSSQMPVRHG
KKLQFMGDKEPTTGAKKSDKPHKQITKRLASDTYPELNLTNIPVFFTHCSGSNKLQEFVN
PSLQREESLGTIQVSNNTKDPKGLTLSRGKGLQIERAVESTSISLVPDTDYGTQDSISLL
EADTLGKAKTAPNQHVSLCAAIESPKELIPGCSKDIRNDTEDFQDPLGHDVNHIQKASIE
MEESELDTQYLQNMFKVSKRQTFALFSNPEKECASVCAHSGSLREQSPRVPLECRQKEEN
QGKSESKIKHVRAINTTVDFPVAGQKDKKLSDHAKRSPERVTRLCQSSQFRGNKTELIIA
NKHGISHNPYLIPSLSPIRSSVKTICKKNLSEEKFEEPVMSPERAMENESIVQSTVRTIS
QNNSRESTFKEVSSSSINEVGSSTNEVGSSINEVGSSGENIQAKLDRNRGPKLSASLRLG
LMQPEVYKQSLPVSNCQLPEIKRQGENEGTLQGVNEDFSPCLNPDNLEQPMGRSHASQVC
SETPDELLNDDKIKESNFAESDIEERSAVFSKSVQKGEFRRSPGPLAHHTSLVQGHERGA
ESSEENVSSEDEELPCFQHLFGKVTNTLSPSTRHNAVATEGLSKETEENLISLKNSLNDC
SDHITSAKASQEHHLHEEARCSDSLFSSRCSAVEDLTANTNTQDPFLMFDPLSKQVGHQS
ENQEVLSDKELVSDDDERETGWEEDNHQEEQSVDSDLGEAASEYESETSLSEDCLGLSSQ
SDILTTQQRDTMQDNLLKIQQEMAELEAVLEQHGSQPSHSSPSLIADSCASEDLLNLEQN
TSEKAVLTSEKSSEYPISQNPESLSADKFQVSPDTSTSKNKEPGMERSSPSKSQLSDNSW
YMHSHSRSLQSRNCPPQKELEAVDVEEQQLTESEAQDLMEQSSLPRQDLEGTPYLESGIS
LFSDDPESDPSEYRAPEPAHVCSMPPSASALKLPQFQAEESARSPAAAHTTNTAGCNVRE
ESVSREKPELIPSTQRGNKRISMVASGLTPKEFVLVHKFARKHHITLTNLITEETTHVIM
KTDWRVMSQNDESLLLVHPAWTTLCEGFLGRQSPSPGGTNGAKRGMSRNAEFVCERTLKY
FLGIAGGKWVVSYFWVTQSIKERKMLDEHDFEVRGDVVNGRNHQGPKRARESQDRKIFKG
LEICCYGPFTNMPTDQLEWMVHLCGASVVKEPSSFTLSQGTQPVVVVQPDAWTEGGGFHV
IGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQVPRAAADSSLPCI
NT seq
5724 nt
NT seq
+upstream
nt +downstream
nt
atggatttttctgcgaatcacgttgaagaagtacaaaatgtccttaatgctatgcagaaa
atcttagagtgtccaatctgtctggagttgatcaaagagcctgtttccacaaagtgtgat
cacatattttgcaaattttgtatgctgaaacttctcaaccagaagaaagggccttcacag
tgtcctctgtgtaagaatcatataaccaaaagaagcctacaagaaagtacaagatttagt
cagcttgttgaagagctattgaagatcattcatgcttttgagcttgacacaggattgcag
attgcaaacagttataacttttcaaaaaaggaaagtaactcttctgagcatctaaaggag
gaagtttctatcattcaaagtatgggctaccgaaaccgggccaaaaaacttcaacagagt
gaacctgaaaatcctaccttggaaaccagtcttagtgtccagctctctaaccttggaatt
gtgagatctctgaggacaaagcagcagatacaacctcagaataagtccgtctacattgaa
ttgggatctgattcttctgaagatacagttaataaggccagttatttcagtgtaggagac
catgaattgttagaaatcacccctcaaggagccaaggctgaagccagtttgaatcgtgca
aaaaaggctgcttgtgagttttctgagaaggacataacaaaggctgaacatcatcaattc
agtaataaagatttgaccaccactgagaagcatgaaactgagaagcatccagaaaagtat
cagggtatttttgtttcaaacttgcatgtggagccatgtggcacagatactcatgccagc
tcattacagcatgaaaacagcagtttattactcactaaagacagaatgaatgtagaaaag
gctgaattctgtaataaaagcaaacagcttgtcttaggaaagagccatcagagcagatgg
gctgaaagtaaggacacatgtaatgataggcagactcccagtacagagaaaaaggtagtt
ctgaatgctgatcccctatatgggagaaaagaactgaataagcagaaacctgcctcctct
gacagtcctagagattcccaagagtttccttggataacactgaatagcagcatacagaga
gttaatgaatggttttccagaagtgacgaaatgctaacttcttacgactcacgtgatggg
gcatttgaatcaaacactgaagtagctcgtgcagtggaagttccaaaggaagttgatgga
tatttgggttcttcagagaaaatagacttaatgaccagtgatcctcatggtgctttaata
catgaaagagtccactccaaaccagtagagagtaatattgaagataaaatatttgggaaa
acctatcagaggaagacaagcctccctaacttgagccgcatagctgaagatctaattata
ggagcatctactgtagaacctcagataacacaagagcgccccctcacaaaaaaactaagg
cgtaaaaggagaagtacatcaggccttcatcctgaggattttatcaagaaagtcgatttg
gcagttcttccaaagactcctgaaaaaataattgagggaactgaccaaacagagcagaat
ggtcatgggataaatattactagtaatggtcatgagactgaaatgaaaggtggttatgtt
cagaaagagaaaaacgctaacctaacagaatcattggaaaaagaatctgctttcagaact
aaggctgaacctataagcagcagtataagcaatatggaactagaattgaatatccatagt
tcaaaagcacctaaaaataggctgaggaggaagtcctctaccaggaacattcatgcactt
gaactagcagtcagtagaaacccaagcccacctaatcatactgaactacaaattgatagt
tgttctagcagtgaagagatgaagaaaaaacattccagccaaatgccagtcaggcacggc
aaaaagcttcaattcatgggagataaagaacctacaactggagccaagaagagtgacaag
ccacacaaacaaataactaagagacttgccagtgacacttacccagaactaaatttaaca
aacatacctgttttttttactcactgttctggttctaataaacttcaagagtttgttaat
cctagccttcaaagagaggagagcctaggaacaattcaagtgtcaaataataccaaagac
cccaaaggtctgacattaagtagaggaaaaggtttgcaaattgaaagagctgtagagagt
accagtatttccttggtacctgatactgattatggcactcaggatagtatctcattactg
gaagctgacaccctagggaaggcaaagacagcaccaaatcaacatgtgagtctgtgtgca
gcaattgaaagccccaaggaacttatccctggttgttctaaagatattagaaacgacaca
gaggactttcaggatccactgggacatgacgttaaccacattcagaaggcgagcatagaa
atggaagagagtgaacttgatacacagtatttgcagaatatgttcaaggtttcaaagcgt
cagacgtttgctctgttttcaaatccagaaaaggaatgtgcatcagtctgtgcccactct
gggtccttaagggaacaaagcccaagagtccctcttgaatgcagacaaaaagaagaaaat
cagggaaagagtgagtctaaaatcaagcatgtgcgggcaattaatacaactgtggacttc
cctgtcgctggtcaaaaagataagaagctgagcgatcatgccaaacgtagcccagaaaga
gtaactaggctttgtcagtcatcacagttcagaggcaacaaaactgagctcattattgca
aataaacatgggatttcacacaacccatatcttataccatcactttctcccatcaggtca
tctgttaaaactatatgtaagaaaaacctgtcagaggaaaagtttgaggaacctgtaatg
tcacctgaaagagcaatggaaaacgagagcatcgttcaaagtacagtgcgcacaattagc
caaaataacagtcgagaaagcacttttaaagaagtcagctcaagcagtattaatgaagta
ggttccagtactaatgaagtaggctctagtattaatgaagtaggttccagtggtgaaaac
attcaagcaaaactagatagaaacagaggacctaaattaagtgcttcgctcagattaggt
cttatgcaacccgaagtctataagcaaagtcttcctgtaagtaactgtcaacttcctgaa
ataaaaaggcaaggagaaaatgaaggcacacttcagggtgttaatgaagatttctcccca
tgtctaaatccagataacctagaacaacctatgggaagaagccatgcttctcaggtttgt
tctgagacacctgatgagttgttaaatgatgacaaaataaaggaaagcaactttgctgaa
agtgacattgaggaaagatctgctgtttttagcaaaagtgtccaaaaaggagaattcaga
aggagccctggccctttagcccatcatacatctttggttcagggtcacgaaagaggggct
gagtcctcagaagagaatgtgtctagtgaggatgaagagcttccttgtttccaacactta
tttggtaaagtaaccaatacactgtctccatctaccagacataatgctgttgccacagag
ggtctatctaaggaaacagaggagaacctaatatcattgaagaatagtttaaatgactgt
agtgaccacataacatcggcaaaggcatcccaggaacatcaccttcatgaggaagcgaga
tgttctgatagcttattttcttcacggtgcagtgcagtggaagacttgaccgctaataca
aacacccaggatcctttcttgatgtttgatcctctttccaaacaagtggggcatcagtct
gaaaaccaggaagttctgagtgacaaggaattggtttcagatgatgacgaaagggaaact
ggctgggaagaggataatcaccaagaagagcagagtgtggattcagacttaggtgaagca
gcatccgagtatgagagtgaaacaagcctctctgaagactgtttggggctgtcctctcag
agcgatatcttaaccactcagcagagggataccatgcaagataacctgctaaagatccag
caggaaatggccgaactggaagctgtgttagagcagcacgggagccagccttctcacagc
tccccttccctcatagccgattcttgtgcctctgaggacctgctaaatctggaacaaaac
acatcagaaaaagcagtattaacttcagagaaaagtagtgaatatcctataagccagaat
ccagaaagcctttctgctgacaagtttcaagtatctccggatacttccaccagtaaaaat
aaagaaccaggaatggaaaggtcttccccttctaaatcgcagttgtcagataatagttgg
tatatgcacagccactcaaggagtcttcagagcagaaactgcccacctcaaaaggagctt
gaggctgttgatgtggaggagcaacagctgacggagtctgaggcccaggatttaatggag
cagtcttctttgccaagacaagatctagagggaaccccttacctagaatctggaatcagc
ctcttctctgatgaccctgagtctgatccctctgaatacagagccccagagccagctcat
gtctgcagcatgccaccctcagcctctgcactgaaattaccccaatttcaagcagaagaa
tctgccaggagtccggctgcagctcatactactaatactgcagggtgtaatgtgagggaa
gaaagtgtgagcagggagaagccagagttgataccttcaacacaaagaggcaacaaaaga
atttctatggtggcatcaggcttgaccccaaaagaatttgtgcttgtgcacaagtttgcc
agaaaacatcacatcactttaactaatctaattactgaagagactactcatgtcattatg
aaaacagattggagagtgatgagccagaacgatgaatcacttctcctagtccaccctgcc
tggactacactgtgtgagggctttctgggaaggcagagcccgagtcctggaggaacaaat
ggggcaaagaggggaatgagcagaaatgctgagtttgtgtgtgaacggacactgaaatat
tttctgggaattgcaggaggaaaatgggtagttagctatttctgggtgacccagtctatt
aaagaaagaaagatgctggatgagcatgattttgaagtcagaggcgatgttgtcaatgga
agaaaccatcaaggcccaaagcgagcaagagaatcccaggacaggaagatcttcaagggc
ttagaaatctgttgctatggaccgtttaccaatatgcccacagatcaactagagtggatg
gtgcatctgtgtggggcttctgtggtgaaggagccctcatcattcaccctcagccagggt
actcaaccagttgtggtcgtgcagccagatgcctggacagagggcggtggcttccatgtc
atcgggcagatgtgtgaagcacctgtggtgacccgagagtgggtattggacagcgtagcc
ctctaccagtgccaggagctggacacctacctgataccccaggtccccagagctgctgct
gattccagcctgccatgtatatag
DBGET
integrated database retrieval system
