Loxodonta africana (African savanna elephant): 100656260
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Entry
100656260 CDS
T04351
Symbol
ALDH7A1
Name
(RefSeq) alpha-aminoadipic semialdehyde dehydrogenase isoform X1
KO
K14085
aldehyde dehydrogenase family 7 member A1 [EC:
1.2.1.31
1.2.1.8
1.2.1.3
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00010
Glycolysis / Gluconeogenesis
lav00053
Ascorbate and aldarate metabolism
lav00071
Fatty acid degradation
lav00260
Glycine, serine and threonine metabolism
lav00280
Valine, leucine and isoleucine degradation
lav00310
Lysine degradation
lav00330
Arginine and proline metabolism
lav00340
Histidine metabolism
lav00380
Tryptophan metabolism
lav00410
beta-Alanine metabolism
lav00561
Glycerolipid metabolism
lav00620
Pyruvate metabolism
lav00670
One carbon pool by folate
lav01100
Metabolic pathways
lav04936
Alcoholic liver disease
Module
lav_M00032
Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
lav_M00135
GABA biosynthesis, eukaryotes, putrescine => GABA
lav_M00555
Betaine biosynthesis, choline => betaine
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
100656260 (ALDH7A1)
00053 Ascorbate and aldarate metabolism
100656260 (ALDH7A1)
00620 Pyruvate metabolism
100656260 (ALDH7A1)
09103 Lipid metabolism
00071 Fatty acid degradation
100656260 (ALDH7A1)
00561 Glycerolipid metabolism
100656260 (ALDH7A1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
100656260 (ALDH7A1)
00280 Valine, leucine and isoleucine degradation
100656260 (ALDH7A1)
00310 Lysine degradation
100656260 (ALDH7A1)
00330 Arginine and proline metabolism
100656260 (ALDH7A1)
00340 Histidine metabolism
100656260 (ALDH7A1)
00380 Tryptophan metabolism
100656260 (ALDH7A1)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
100656260 (ALDH7A1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
100656260 (ALDH7A1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100656260 (ALDH7A1)
Enzymes [BR:
lav01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.3 aldehyde dehydrogenase (NAD+)
100656260 (ALDH7A1)
1.2.1.8 betaine-aldehyde dehydrogenase
100656260 (ALDH7A1)
1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase
100656260 (ALDH7A1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Aldedh
Motif
Other DBs
NCBI-GeneID:
100656260
NCBI-ProteinID:
XP_003404516
UniProt:
G3TKZ8
LinkDB
All DBs
Position
Unknown
AA seq
539 aa
AA seq
DB search
MWRFSCALCLHTAKRSKSLGLWSRPAAFMSTLLINEPQYVWLKELGLREENEGVYNGSWG
GRGEVVTTYCPANNEPIARVRQASIADYEETVKKAREAWKIWADIPAPKRGEVVRQIGDA
LREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERPGHALIE
QWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLED
NKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVALMVQERFGRSLLELGGN
NAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFLHESIHDEVVNKLKKAYAQICVG
NPWDSNVLYGPLHTKQAVNMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLAHD
ASIVHTETFAPILYVFKFKNEDEVFAWNNEVKQGLSSSIFTRDLGRIFRWLGPKGSDCGI
VNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ
NT seq
1620 nt
NT seq
+upstream
nt +downstream
nt
atgtggcgcttctcctgcgccctctgtctgcacactgcaaagaggagcaagtccttaggc
ctttggagcaggcctgccgccttcatgtccactctgctgatcaatgagccccagtatgtt
tggctgaaagagctggggctccgcgaggaaaacgagggcgtgtataatggaagctgggga
ggccggggagaggtggttacaacctattgtcctgctaacaatgagccaatagcaagagtc
cgacaggccagcatagcagactatgaagaaactgtaaagaaagcaagagaagcatggaaa
atatgggcggatattcctgctccaaagcgaggtgaagtagtaagacagattggtgatgcc
ttacgggagaagatccaagtgctaggaagcttggtgtctctggagatgggaaaaatctta
gtagaaggtgtgggagaagttcaagagtatgtggatatttgtgattatgctgttggctta
tcgcggatgattgggggacccatcttgccttctgaaagacctggccatgccctcattgag
cagtggaatcctgtaggcctggttgggatcatcactgctttcaacttccccgtggcagtg
tatggctggaacaatgccatcgcgatgatctgtgggaatgtctgcctttggaaaggcgct
ccaacaacttccctcattagtgtagctgtcacaaagataatagccaaagttctggaggac
aacaaactgcctggtgcaatttgttccctgacttgtggtggagcagacattggcacagca
atggccaaagatgagcgggtgaacctgctgtccttcactgggagcactcaggtgggaaaa
caagtggcccttatggtacaggagaggtttgggagaagtttgttagaacttggaggaaac
aatgccataattgcttttgaggatgcagacctcagcttagtcgttccatcagctctcttt
gcagccgtggggacagctggccagaggtgtacaactgcgaggcgactgtttttacatgaa
agcatccatgatgaagttgtaaataaacttaaaaaggcctacgcacagatctgtgtcggg
aacccatgggactctaatgttctctatgggccactccacacaaagcaggcagtgaacatg
ttccttggtgcggtggaagaagcaaagaaagaaggtggcacagtggtctatggtggcaag
gtcatggatcgtcctgggaactatgtagaaccgacgattgtgacaggccttgcccatgat
gcatccattgtgcacacagagacttttgctccaattctttatgtctttaaatttaagaat
gaagacgaggtctttgcatggaataatgaagtaaaacagggactttcaagtagtatattt
accagggatttgggaagaatcttccgctggcttggacctaaaggatcagactgtggcatc
gtcaacgtcaatattccaacgagtggggctgagatcggaggtgcatttggaggtgaaaaa
catactggtggtggcagggagtctggcagtgatgcctggaaacagtacatgagaagatct
acttgtaccatcaactacagcaaggaccttcctctggcccaaggaatcaagtttcagtaa
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