Loxodonta africana (African savanna elephant): 100659299
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Entry
100659299 CDS
T04351
Symbol
HSD17B4
Name
(RefSeq) peroxisomal multifunctional enzyme type 2
KO
K12405
(3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.-
4.2.1.107
4.2.1.119
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00120
Primary bile acid biosynthesis
lav01040
Biosynthesis of unsaturated fatty acids
lav01100
Metabolic pathways
lav01212
Fatty acid metabolism
lav04146
Peroxisome
Module
lav_M00104
Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
lav_M00861
beta-Oxidation, peroxisome, VLCFA
lav_M00862
beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09103 Lipid metabolism
00120 Primary bile acid biosynthesis
100659299 (HSD17B4)
01040 Biosynthesis of unsaturated fatty acids
100659299 (HSD17B4)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
100659299 (HSD17B4)
Enzymes [BR:
lav01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.107 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase
100659299 (HSD17B4)
4.2.1.119 enoyl-CoA hydratase 2
100659299 (HSD17B4)
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Paralog
GFIT
Motif
Pfam:
MFE-2_hydrat-2_N
adh_short
adh_short_C2
SCP2
MaoC_dehydratas
KR
FAS1_DH_region
Alkyl_sulf_C
Epimerase
3HCDH_N
Motif
Other DBs
NCBI-GeneID:
100659299
NCBI-ProteinID:
XP_023403347
LinkDB
All DBs
Position
Unknown
AA seq
720 aa
AA seq
DB search
MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGASVVVNDIGGDVKGDGKSSLAADKVVE
EIRRKGGKAVASYDTVEAGEKIVKTALDAFGRIDIVVNNAGILRDRSFARTSDEDWDLIH
RVHLRGSFQVTRAAWDHMKKQNYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLSNTLAI
EGRKSNIHCNTIAPAAGSRMTETVLPEDILEGLKPDYVAPLVLWLCHESCDENGSLFEVG
AGWIGKLRWQRTVGAIVRQRNQPMTPEAVRANWAKICDFDNTSTPQSVQDSTGSMIGVLS
KIDSGGVSTNRTSHAASTTTSGFDEAIGYQLPPFYSAYTELEAIMYALGVGASVKDPKDL
KFVYEGSSDFSCLPTFAVVLAQKSVMSGDLGAVPGLSINLSKVLHGEQYLELYKPLPRTG
KLRSEARVADVLDKGSGSVILIDVYSYYEKELICYNQFSIFVVGSGGFGGKQSSDKVKET
AAIPNRPPDAVLTDTSSHDQLNYFSFLGFDKPILHGLCTFGFSARHVLKQFADNDVSRFK
AIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKIQGSRDIVISNAYVDLVPTSGASDISTT
SEDGELQSTLVFKEIGRRLKDVGHKVVKKVNAVFEWHITKGRNVAAKWTIDLKSGSGEAY
QGPARGSADTTIIISDEDFMEVVQGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
NT seq
2163 nt
NT seq
+upstream
nt +downstream
nt
atggcctcgccgctgaggttcgacgggcgggtggtgctggtcaccggtgcggggggagga
ctggggcgagcctatgccttggcttttgcagaaagaggtgcatcagttgttgtgaatgat
ataggaggagacgttaaaggagatggtaaaagctccttagctgctgataaagttgttgaa
gaaataagaaggaaaggtggaaaagcagtggccagctatgatacagtggaagcaggagag
aagattgtgaagacagcattggatgcctttggaagaatagatattgtggtcaacaatgct
gggattctgagggatcgttcctttgctaggacaagtgatgaagactgggatctaatccat
agagttcatttgcggggctcgttccaggtgacccgggcagcatgggatcacatgaagaaa
cagaattacggaaggatcattatgacttcatcagcttcaggaatatatggcaacttcggc
caggcaaattatagtgctgcaaagttgggtcttctgggtctatcaaatactcttgcaatt
gaaggcaggaaaagcaacattcattgtaacactattgcccctgctgcgggatcacggatg
actgagactgttttgccagaagatattctagaaggcctgaagccggattatgtggcaccc
ctggtcctttggctttgccatgagagttgtgacgaaaacggtagcttgtttgaggtggga
gcaggatggattggaaaattacgctggcagcggactgttggagctatcgtaaggcagagg
aatcagccaatgactcctgaggcagtgagggccaactgggcgaagatctgtgactttgat
aataccagcacgccccagagtgtacaagactcaactgggagtatgattggagttctaagt
aaaatagattcgggaggagtttcgacaaatcgtaccagtcatgcagcatcaacaaccaca
tcaggatttgatgaagctattggctatcagcttcctccgttttattctgcttatactgaa
ctggaagctattatgtatgcccttggagtgggagcgtcagtcaaggatccaaaagatttg
aaattcgtttacgaaggaagttctgatttctcctgtttgcctacctttgcagttgtctta
gctcagaaatctgtaatgagtggagatctaggagcagttcctgggctttcaatcaactta
tcaaaggttcttcatggggagcaatacttggagttatataaaccacttcccagaacagga
aaattaagatctgaagcacgtgttgctgatgtcctggataaaggatccggctcagtaatt
cttatagacgtttattcgtattatgagaaggaacttatatgttacaatcagttctctatc
ttcgttgttggctctggagggtttggtggaaaacaatcatcagacaaagtcaaggaaact
gcagccatacctaatagacctcctgacgctgtacttacagataccagctcacatgaccag
ctaaattatttctcttttttaggttttgacaagcccatattacatggattatgcacattt
ggattttctgccaggcatgttttaaagcagtttgcagataatgatgtgtccagattcaag
gcaattaaggttcgttttgcaaaaccagtatatccaggtcaaactctacaaactgagatg
tggaaggaaggaaacagaatccattttcaaactaagatccaaggaagtagagacattgtc
atttcaaatgcatatgtagatcttgtgccaacatctggagcatctgatatttcaacaacc
tctgaggacggagagcttcagagtacccttgtgtttaaggaaataggtcgccgccttaag
gatgttgggcataaggtggtaaagaaagtaaatgctgtatttgagtggcatatcaccaaa
ggtagaaatgttgcagctaagtggactattgacctaaaaagtggttctggagaagcatat
caaggccctgcaagaggctctgctgatacaaccatcatcatttcagatgaagatttcatg
gaggtggttcagggcaagcttgaccctcaaaaggcattctttagtggccgactgaaggca
agaggaaacatcatgctgagccagaagcttcagatgatcctgaaagactacgctaagctt
tga
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