Loxodonta africana (African savanna elephant): 100660114
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Entry
100660114 CDS
T04351
Symbol
HK2
Name
(RefSeq) hexokinase-2
KO
K00844
hexokinase [EC:
2.7.1.1
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00010
Glycolysis / Gluconeogenesis
lav00051
Fructose and mannose metabolism
lav00052
Galactose metabolism
lav00500
Starch and sucrose metabolism
lav00520
Amino sugar and nucleotide sugar metabolism
lav00524
Neomycin, kanamycin and gentamicin biosynthesis
lav01100
Metabolic pathways
lav01200
Carbon metabolism
lav01250
Biosynthesis of nucleotide sugars
lav04066
HIF-1 signaling pathway
lav04910
Insulin signaling pathway
lav04930
Type II diabetes mellitus
lav04973
Carbohydrate digestion and absorption
lav05230
Central carbon metabolism in cancer
Module
lav_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
lav_M00549
UDP-Glc biosynthesis, Glc => UDP-Glc
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
100660114 (HK2)
00051 Fructose and mannose metabolism
100660114 (HK2)
00052 Galactose metabolism
100660114 (HK2)
00500 Starch and sucrose metabolism
100660114 (HK2)
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
100660114 (HK2)
09110 Biosynthesis of other secondary metabolites
00524 Neomycin, kanamycin and gentamicin biosynthesis
100660114 (HK2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
100660114 (HK2)
09150 Organismal Systems
09154 Digestive system
04973 Carbohydrate digestion and absorption
100660114 (HK2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
100660114 (HK2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
100660114 (HK2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
lav04131
]
100660114 (HK2)
Enzymes [BR:
lav01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.1 hexokinase
100660114 (HK2)
Membrane trafficking [BR:
lav04131
]
Autophagy
Mitophagy
Other mitophagy associated proteins
100660114 (HK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Hexokinase_2
Hexokinase_1
FGGY_N
Motif
Other DBs
NCBI-GeneID:
100660114
NCBI-ProteinID:
XP_003413750
UniProt:
G3T910
LinkDB
All DBs
Position
Unknown
AA seq
917 aa
AA seq
DB search
MIASHLLAYFFTELNHDQVQKVDQYLYHMRLSDETLQEISKRFRKEMEKGLGATTHPTAS
VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLWVKVTDNGLQRVEIENKIYAIPEDIMR
GSGTQLFDHIAECLANFMEQLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGV
EGRDVVALIREAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYME
EMRHIDMVEGDEGRMCINMEWGAFGDDGTLNDIRTEFDREIDMGSLNPGKQLFEKMISGM
YMGELVRLILVKMAKEELLFGGKLSPELLTTGCFETKDVSDIEGEKDGIRKAHEILVRLG
LDPTQEDCVATRRICQIVSTRSANLCGATLAAVLRRIKENKGEDRLRSTIGVDGSVYKKH
PHFAKCLHKTVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLEPLMLS
HEQLLEVKRRMKVEMEQGLRKETHANAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV
LLVRVRNGKRRGVEMHNKIYSIPQDVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGF
TFSFPCHQNRLDESILLTWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVG
TMMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDD
FRTEFDVMVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRG
IFETKFLSQIESDCLALLQVRAILQHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA
VVDKIRENRGLDTLKVTVGVDGTLYKLHPHFAKIMHETVKSLAPRCDVSFLESEDGSGKG
AALITAVACRIREAGQR
NT seq
2754 nt
NT seq
+upstream
nt +downstream
nt
atgatcgcctcgcatctgctcgcctacttcttcacggaactcaaccatgaccaagtgcag
aaagtcgaccagtatctctaccacatgcgactctctgatgagacccttcaggagatctct
aagcggttccgcaaggagatggagaaagggcttggagctactacccaccccactgcttca
gtgaaaatgctgcccacctttgtgaggtctactccagatgggacagaacatggagagttc
ctggccctggaccttggagggaccaacttccgtgtgctgtgggtgaaagtaacggacaat
ggcctccaaagggtggagatagagaacaagatctacgccatccctgaggacattatgcgg
ggcagcggcacccagctgtttgaccacattgccgagtgcctggccaacttcatggaacag
ctacaaatcaaagacaagaagctcccgctgggttttaccttctccttcccctgccaccag
actaaactagatgagagcttcctggtctcgtggactaaggggttcaagtccagtggtgtg
gagggcagagacgtggtggctcttatccgggaggccatccagaggagaggggactttgat
attgatatcgtggctgtggtgaacgacacagttgggaccatgatgacctgtggttatgat
gaccagaactgtgaaattggtctcattgtgggcacgggcagcaatgcctgctacatggag
gagatgcgtcacatcgacatggtggagggcgacgaggggcggatgtgcatcaacatggag
tggggggcctttggggacgacggcacgctcaacgacattcgtactgagtttgaccgggag
atcgacatgggctcgctgaaccccgggaagcaactatttgagaagatgatcagtgggatg
tacatgggggagctggtgaggctgatcctagtgaagatggccaaggaggagctgctcttt
ggggggaagctcagcccagagctcctcaccacaggctgctttgagaccaaggatgtttca
gatattgaaggcgagaaggatggcatccggaaggcccacgagatccttgtacggctgggc
ctggacccaacacaagaggactgtgtagccactcgccggatctgccagattgtgtccaca
cgctcagccaacctgtgtggggccactctggcagcagtgctgcggcgcatcaaggagaac
aaaggagaggaccggctgcgctccaccattggggtcgatggctccgtctacaagaaacac
ccccacttcgccaagtgtcttcacaagactgtgcggcgcctggtgcctgactgtgatgtc
cgctttctccgctctgaggatggcagtggcaagggggcggccatggtgacagcagtggcc
taccggctggccgatcaacaccgagctcggcagaagaccctagagcctctgatgctgagc
catgagcagctgctggaggtcaagaggaggatgaaggtggaaatggagcaaggcctgaga
aaggaaacgcatgccaatgcccctgtcaagatgttgcccacctatgtgtgtgccacccct
gatggcacagagaaaggtgacttcttggccttggacctgggggggacgaatttccgggtc
ctgctggtacgcgtgcggaatgggaagcgacgtggggtggagatgcacaacaagatctac
tccatcccgcaggatgtcatgcatggcacaggggacgagctctttgaccacatcgtccag
tgcattgctgacttcctcgagtatatggggatgaagggcgtgtccctgcctctgggattc
accttctccttcccctgccatcagaacagactggatgagagcatcctcctcacgtggaca
aaaggcttcaaggcatctggctgcgagggcgaggatgtggtcaccctgctgaaggaagcg
attcaccggcgagaggagtttgacctagatgtggttgccgtggtgaatgacacagttgga
acaatgatgacctgtggctatgaggatcctcactgtgaagttggcctcatcgttggtacg
ggcagcaatgcttgctacatggaggagatgcggaacgtggaactggtggaaggggaggaa
gggcggatgtgtgtcaacatggagtggggcgcctttggggacaatggatgcctagatgac
ttccgcactgaatttgatgtgatggtggatgagctttccctcaaccctggcaaacagagg
ttcgagaaaatgatcagtggcatgtacctgggcgagattgtccgtaacatcctcatcgat
ttcaccaagcgtggactccttttccgcggtcgcatctcagagcgactcaagacacgggga
atctttgaaaccaagttcctgtctcagattgagagtgactgcctggcactgttgcaggtc
cgggccatcctgcagcacttggggcttgagagcacctgtgatgacagcatcatcgtcaag
gaggtgtgcactgtggtggcgcggagggcagcccagctctgtggtgcaggcatggccgct
gtggtggacaaaatacgagaaaatcgtggactggacaccctcaaagtgactgtgggcgtg
gatgggaccctctacaagctacatcctcactttgccaaaatcatgcatgagacggtcaag
agcctggctccgagatgtgacgtgtccttcctggagtccgaggatggcagcggaaagggg
gcggctctcatcactgctgttgcctgccgcatccgtgaagctggacagcgatag
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