Loxodonta africana (African savanna elephant): 100661616
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Entry
100661616 CDS
T04351
Symbol
ADCY8
Name
(RefSeq) adenylate cyclase type 8
KO
K08048
adenylate cyclase 8 [EC:
4.6.1.1
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00230
Purine metabolism
lav01100
Metabolic pathways
lav01522
Endocrine resistance
lav04015
Rap1 signaling pathway
lav04020
Calcium signaling pathway
lav04022
cGMP-PKG signaling pathway
lav04024
cAMP signaling pathway
lav04062
Chemokine signaling pathway
lav04072
Phospholipase D signaling pathway
lav04081
Hormone signaling
lav04082
Neuroactive ligand signaling
lav04114
Oocyte meiosis
lav04211
Longevity regulating pathway
lav04213
Longevity regulating pathway - multiple species
lav04261
Adrenergic signaling in cardiomyocytes
lav04270
Vascular smooth muscle contraction
lav04371
Apelin signaling pathway
lav04540
Gap junction
lav04611
Platelet activation
lav04713
Circadian entrainment
lav04714
Thermogenesis
lav04720
Long-term potentiation
lav04723
Retrograde endocannabinoid signaling
lav04724
Glutamatergic synapse
lav04725
Cholinergic synapse
lav04727
GABAergic synapse
lav04742
Taste transduction
lav04750
Inflammatory mediator regulation of TRP channels
lav04911
Insulin secretion
lav04912
GnRH signaling pathway
lav04913
Ovarian steroidogenesis
lav04914
Progesterone-mediated oocyte maturation
lav04915
Estrogen signaling pathway
lav04916
Melanogenesis
lav04918
Thyroid hormone synthesis
lav04921
Oxytocin signaling pathway
lav04923
Regulation of lipolysis in adipocytes
lav04925
Aldosterone synthesis and secretion
lav04926
Relaxin signaling pathway
lav04927
Cortisol synthesis and secretion
lav04928
Parathyroid hormone synthesis, secretion and action
lav04934
Cushing syndrome
lav04935
Growth hormone synthesis, secretion and action
lav04970
Salivary secretion
lav04971
Gastric acid secretion
lav04972
Pancreatic secretion
lav04976
Bile secretion
lav05032
Morphine addiction
lav05163
Human cytomegalovirus infection
lav05166
Human T-cell leukemia virus 1 infection
lav05200
Pathways in cancer
lav05207
Chemical carcinogenesis - receptor activation
lav05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100661616 (ADCY8)
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
100661616 (ADCY8)
04371 Apelin signaling pathway
100661616 (ADCY8)
04020 Calcium signaling pathway
100661616 (ADCY8)
04072 Phospholipase D signaling pathway
100661616 (ADCY8)
04024 cAMP signaling pathway
100661616 (ADCY8)
04022 cGMP-PKG signaling pathway
100661616 (ADCY8)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
100661616 (ADCY8)
04081 Hormone signaling
100661616 (ADCY8)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
100661616 (ADCY8)
09144 Cellular community - eukaryotes
04540 Gap junction
100661616 (ADCY8)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100661616 (ADCY8)
04062 Chemokine signaling pathway
100661616 (ADCY8)
09152 Endocrine system
04911 Insulin secretion
100661616 (ADCY8)
04923 Regulation of lipolysis in adipocytes
100661616 (ADCY8)
04912 GnRH signaling pathway
100661616 (ADCY8)
04913 Ovarian steroidogenesis
100661616 (ADCY8)
04915 Estrogen signaling pathway
100661616 (ADCY8)
04914 Progesterone-mediated oocyte maturation
100661616 (ADCY8)
04921 Oxytocin signaling pathway
100661616 (ADCY8)
04926 Relaxin signaling pathway
100661616 (ADCY8)
04935 Growth hormone synthesis, secretion and action
100661616 (ADCY8)
04918 Thyroid hormone synthesis
100661616 (ADCY8)
04928 Parathyroid hormone synthesis, secretion and action
100661616 (ADCY8)
04916 Melanogenesis
100661616 (ADCY8)
04925 Aldosterone synthesis and secretion
100661616 (ADCY8)
04927 Cortisol synthesis and secretion
100661616 (ADCY8)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
100661616 (ADCY8)
04270 Vascular smooth muscle contraction
100661616 (ADCY8)
09154 Digestive system
04970 Salivary secretion
100661616 (ADCY8)
04971 Gastric acid secretion
100661616 (ADCY8)
04972 Pancreatic secretion
100661616 (ADCY8)
04976 Bile secretion
100661616 (ADCY8)
09156 Nervous system
04724 Glutamatergic synapse
100661616 (ADCY8)
04727 GABAergic synapse
100661616 (ADCY8)
04725 Cholinergic synapse
100661616 (ADCY8)
04720 Long-term potentiation
100661616 (ADCY8)
04723 Retrograde endocannabinoid signaling
100661616 (ADCY8)
09157 Sensory system
04742 Taste transduction
100661616 (ADCY8)
04750 Inflammatory mediator regulation of TRP channels
100661616 (ADCY8)
09149 Aging
04211 Longevity regulating pathway
100661616 (ADCY8)
04213 Longevity regulating pathway - multiple species
100661616 (ADCY8)
09159 Environmental adaptation
04713 Circadian entrainment
100661616 (ADCY8)
04714 Thermogenesis
100661616 (ADCY8)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100661616 (ADCY8)
05207 Chemical carcinogenesis - receptor activation
100661616 (ADCY8)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100661616 (ADCY8)
05163 Human cytomegalovirus infection
100661616 (ADCY8)
09165 Substance dependence
05032 Morphine addiction
100661616 (ADCY8)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
100661616 (ADCY8)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100661616 (ADCY8)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
100661616 (ADCY8)
Enzymes [BR:
lav01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
100661616 (ADCY8)
BRITE hierarchy
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Ortholog
Paralog
GFIT
Motif
Pfam:
Guanylate_cyc
Adcy_cons_dom
AC_N
TBK1_ULD
Motif
Other DBs
NCBI-GeneID:
100661616
NCBI-ProteinID:
XP_010586798
LinkDB
All DBs
Position
Unknown
AA seq
1067 aa
AA seq
DB search
MNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTYLQY
SGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQV
ILQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLE
TENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFT
NLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVE
MGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGG
IPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEDSLLSLPEDIVKE
SVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGP
EEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLL
FITAIQSLLPSSRVMPLAIQFSVLIMLHSALVLITTAEDYKCLPLVLRKTCCWINETYLA
RNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLAM
VTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNLNHSGEDFLGTKEASLLL
MAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFL
EKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLSE
DRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWDHLCALADFSLALSESIQEINKHSFNN
FELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQG
FAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLN
RQRQKQLLNENNNTGIIKAHYNRRTLLTPSGPEPGAQAEGTDKSDLP
NT seq
3204 nt
NT seq
+upstream
nt +downstream
nt
atgaacgtgctggacgtgctgactaaactcaccctcttggttctccacttgagcctggcc
tcggcacccatggacccgctcaagggcattctgttgggtttcttcaccggcatcgaggtg
gtaatctgcgccctggtggtggtcaggaaggacaccacctcacacacgtacctgcagtac
agcggcgtggtcacctgggtggccatgaccacccaaatcctggcagcaggccttggctat
gggctcctgggtgacggcatcggttacgtgctcttcacgctcttcgccacctacagcatg
ctgccgctgcccctcacctgggccatcctggccggcctgggcacctcgctgctccaggtg
atcctccaagtggtcatccccagactggcggtcatttccatcaaccaggtggtggcccag
gcagtgttattcatgtgtatgaacacagctgggatcttcatcagttacctgtcagaccgg
gcccagcgccaagccttcctggagactcggaggtgtgtggaggccaggctgcgcctggaa
acagagaaccagagacaggagcggcttgtgctgtctgtgctccccaggtttgttgtcctg
gaaatgatcaacgacatgactaatgtggaagacgagcacctgcagcaccagttccaccgg
atctacatccaccgctatgagaatgtcagtattcttttcgcagatgttaaaggatttacc
aacctctccacgaccttgtctgctcaggagctggtcaggatgctcaacgagctctttgcc
agatttgatcgcctggcccatgagcatcactgtcttcgcattaaaatcctgggagactgc
tactattgcgtttccggacttcctgaaccccgccaggaccacgcccactgctgtgttgaa
atgggcctcagcatgattaaaaccatcaggtatgtgcgatcaaggacaaagcatgacgtt
gacatgcggattggaatccactcaggctcagtgctctgtggcgtgttgggcctgcggaag
tggcagtttgatgtctggtcttgggatgtggacattgcgaacaaactcgaatctggagga
atccctgggaggattcacatttccaaggccacactggactgcctcaatggtgactacaat
gtggaagaggggcacggtaaagagaggaatgaattcctgaggaagcataatatagagacc
tatttaattaagcagcctgaggacagtctgctgtctttgcccgaagacattgtcaaggag
tcggtgagctcctcggacaggagaaacagtggagcaaccttcacagaagggtcctggagc
cccgagctgccctttgataacatagtggggaaacagaacactctggctgccctaacaaga
aattcaataaatctgcttccaaaccatctcgcacaagctttgcatgtccagtcggggcct
gaggaaattaacaagagaatagaacataccatcgacttgcggagtggcgataaattgcga
agagagcatatcaagccattctcactgatgtttaaagactccagcctggagcacaagtac
tctcaaatgagggatgaagtattcaagtcaaacttggtctgtgcatttatcgttcttcta
ttcatcacggcaatccaaagtttgcttccttcttcaagggtgatgccgttggccatccag
ttttccgttctgattatgctgcactcggctctggtcctcatcaccacagcagaggattat
aagtgcttgcccctcgtccttcggaaaacttgctgttggattaatgagacctatttggca
cggaatgtcatcatctttgcatccatcttgattaatttcctgggtgccatcctaaatatc
ctgtggtgtgattttgacaagtcgatacccttgaagaacctgactttcaattcctcagct
gtgtttacagatatctgctcctacccagagtatttcgtcttcacgggtgtgttggccatg
gtgacctgtgcggtattcctgcgacttaactccgtcctgaagctagccgtgctactgatt
atgatcgccatctatgccctactgaccgaaaccatctatgcaggcctctttctgcgttat
gacaacctgaaccacagtggagaagatttcctggggaccaaggaggcatcgctcctgcta
atggccatgttcctccttgctgtgttctaccatggacagcagctggagtacaccgcccgc
ctggacttcctgtggcgagtgcaggccaaggaggagatcaacgagatgaaggagctgagg
gaacacaacgagaacatgctccggaacatcctgcccagccacgtggcccgccacttcctg
gagaaagaccgggacaacgaggagctgtattctcagtcctatgatgctgttggggtgatg
ttcgcctccattccagggtttgccgacttttactcccagactgaaatgaacaaccaagga
gtggaatgcctgcgcttgctgaatgagatcattgctgacttcgatgaattgctcagcgag
gaccggtttcaagacattgaaaaaatcaagaccattggcagcacctacatggcagtgtca
ggcctgtcacctgaaaaacagcaatgtgaagacaagtgggatcatctgtgtgccctggcc
gacttctctctcgccctgtctgaaagcatacaggagatcaacaagcattcgttcaacaac
ttcgagctgcggatcggcatcagccatggctcagtggtagctggcgttattggcgctaag
aaaccccagtatgacatttggggcaaaaccgtgaacctggccagccgaatggatagcaca
ggggtcagcggcaggatccaagtcccagaggagacctatctcatcctgaaagaccagggc
tttgccttcgactaccgaggggagatctatgtgaagggcatcagtgaacaggaaggaaaa
atcaaaacatactttctcctgggaagagtccagcccaacccattcatcctgcccccaaga
agactgcccgggcaatactccttggccgcggtcgtcctcgggctcgtgcagtccctcaac
aggcaaaggcagaagcagctcctcaacgagaataacaacacggggatcatcaaggcccat
tacaaccggcggactttgttaactcccagtgggcccgagcccggagcccaagccgaaggc
accgacaaatccgatttgccataa
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integrated database retrieval system
