Loxodonta africana (African savanna elephant): 100668116
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Entry
100668116 CDS
T04351
Symbol
INSR
Name
(RefSeq) LOW QUALITY PROTEIN: insulin receptor
KO
K04527
insulin receptor [EC:
2.7.10.1
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav04010
MAPK signaling pathway
lav04014
Ras signaling pathway
lav04015
Rap1 signaling pathway
lav04022
cGMP-PKG signaling pathway
lav04066
HIF-1 signaling pathway
lav04068
FoxO signaling pathway
lav04072
Phospholipase D signaling pathway
lav04081
Hormone signaling
lav04150
mTOR signaling pathway
lav04151
PI3K-Akt signaling pathway
lav04152
AMPK signaling pathway
lav04211
Longevity regulating pathway
lav04213
Longevity regulating pathway - multiple species
lav04520
Adherens junction
lav04910
Insulin signaling pathway
lav04913
Ovarian steroidogenesis
lav04923
Regulation of lipolysis in adipocytes
lav04930
Type II diabetes mellitus
lav04931
Insulin resistance
lav04932
Non-alcoholic fatty liver disease
lav04960
Aldosterone-regulated sodium reabsorption
lav05010
Alzheimer disease
lav05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
100668116 (INSR)
04015 Rap1 signaling pathway
100668116 (INSR)
04066 HIF-1 signaling pathway
100668116 (INSR)
04068 FoxO signaling pathway
100668116 (INSR)
04072 Phospholipase D signaling pathway
100668116 (INSR)
04022 cGMP-PKG signaling pathway
100668116 (INSR)
04151 PI3K-Akt signaling pathway
100668116 (INSR)
04152 AMPK signaling pathway
100668116 (INSR)
04150 mTOR signaling pathway
100668116 (INSR)
09133 Signaling molecules and interaction
04081 Hormone signaling
100668116 (INSR)
09150 Organismal Systems
09152 Endocrine system
04923 Regulation of lipolysis in adipocytes
100668116 (INSR)
04913 Ovarian steroidogenesis
100668116 (INSR)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
100668116 (INSR)
09149 Aging
04211 Longevity regulating pathway
100668116 (INSR)
04213 Longevity regulating pathway - multiple species
100668116 (INSR)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100668116 (INSR)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100668116 (INSR)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
100668116 (INSR)
04932 Non-alcoholic fatty liver disease
100668116 (INSR)
04931 Insulin resistance
100668116 (INSR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lav01001
]
100668116 (INSR)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
lav04090
]
100668116 (INSR)
Enzymes [BR:
lav01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100668116 (INSR)
Protein kinases [BR:
lav01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
100668116 (INSR)
CD molecules [BR:
lav04090
]
Proteins
100668116 (INSR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
Insulin_TMD
fn3
Kinase-like
B2
DUF4476
Motif
Other DBs
NCBI-GeneID:
100668116
NCBI-ProteinID:
XP_023396235
LinkDB
All DBs
Position
Unknown
AA seq
1365 aa
AA seq
DB search
MIYMWRVCLPVLFSLPVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLS
FPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLM
NITRGAVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEECGDICPGTAKGKTNCP
ATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSEPDDPTKCVACRN
FYLDGRCVETCPPLYYHFQDWRCVNFSFCQDLHNKCKNSRRQGCHQYVIHNNKCIPECPS
GYTMNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCTVVNGSLIINIRGGNNL
AAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGESLEVGNYSFYALDNQNLRQ
LWDWSKHNLTITRGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIAVKTNGDQASCEN
ELLKFSYIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWT
VVDIDPPQRSNDPKSQPHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQT
DATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWERQAEDSELYELDYCLKG
LKLPSRTWSPPFESEESQKHNQSDYEESASDCCACPKTDSQILKELEESSFRKTFEDYLH
NVVFVPRKTSSGPGAEDPRPSRKRRALGDVGNVTVAVPTIPGFPNVSSTRVPTSPAEHRP
FEKVVNKESLVISGLRHFTGYRIEVQACNQDAPEERCSVAAYVSARTMPEAKADDIVGPV
THEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVXRRHFARERGCRLRGLP
PGNYSCACGATSLAGNGSWTEATHFYVTDYLDVPSNIAKIIIGPLIFVFLVSVVIGSIYL
FLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPREKITLLRELGQGSFGMV
YEGNARDIVKGEAETHVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQ
PTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVH
RDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSS
DMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTSLMQMCWQFNP
KMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEMEFEDMENIPLDQSSHSQR
DEARGRDGGSSLSLKRNYDEHIPYTHMNGGKKNGRILPLPRSNPS
NT seq
4098 nt
NT seq
+upstream
nt +downstream
nt
atgatctacatgtggcgtgtttgcttacctgtcctgttttctcttccagtgtgtcctggc
atggatattcggaacaacctcacccggctgcacgagctggagaactgttctgtcattgaa
ggacatttgcagatattgttgatgtttaaaacgaggcccgaagatttccgagacctcagt
ttccccaaactcatcatgatcactgactacttgttgctcttccgggtctatgggctcgag
agcctcaaggacctgttccccaacctcacagtcatccggggctcacgcctcttcttcaac
tatgcgctggtcattttcgagatggtgcacctgaaggagcttggcctctacaacctgatg
aatatcacccggggggctgtccgcatcgagaagaacaatgagctgtgctacctggccacc
attgactggtcacgcatcctggactctgtggaggataattacatcgtgctgaacaaagac
gacaatgaagagtgcggggacatctgtccgggcactgccaagggcaagaccaactgccca
gccactgtcatcaatgggcagtttgttgagcggtgttggacccatagccactgccagaaa
gtttgcccgaccatctgtaagtctcacggctgcaccgctgaaggcctgtgctgccacagt
gagtgtctgggcaactgctccgagcccgacgaccccaccaagtgcgtggcctgccgcaac
ttctacctggacggcaggtgcgtggagacctgcccgcccctctactaccacttccaggac
tggcgctgcgtcaacttcagcttctgccaggacctgcacaacaaatgcaagaactcacgg
aggcagggctgccaccagtacgtcattcacaacaacaagtgcatccccgagtgtccctct
ggatacacgatgaactccagcaacctcatgtgcaccccatgcttgggcccctgccccaag
gtttgccacctcctggagggcgagaagaccatcgactcggtgacgtctgcccaggagctc
cgggggtgcaccgtggtcaacgggagcctgatcatcaacatccgaggaggcaacaacctg
gcagctgagctagaggccaacctaggtctcattgaagagatttcagggtatctcaaaatt
cgccgatcctacgctctcgtgtcactttccttcttccggaagttacgtctgattcgagga
gagagcctagaagtcgggaactactccttctacgccttggacaatcagaacctaaggcag
ctatgggactggagcaaacacaacctcaccatcactcgggggaaactcttcttccactat
aaccccaagctttgcttgtcagaaattcataagatggaggaagtttcgggaaccaagggg
cgccaggaaagaaacgacattgccgtgaagaccaatggggatcaggcatcctgtgaaaat
gaattacttaaattttcttacatccggacatcttttgacaagatcttgctcaggtgggag
ccatattggccccccgacttccgagacctcctggggttcatgcttttctataaagaggcc
ccctatcagaatgtgacagaatttgacgggcaggatgcctgtggttccaacagctggacg
gtggtggacattgacccgccccagaggtccaacgaccccaagtcacagccccaccctggg
tggctgatgcggggcctcaagccctggactcagtacgccatctttgtcaagaccttggtc
accttttctgatgagcgccggacctatggggccaagagtgacatcatctatgtccagaca
gatgctaccaatccttccgtccctctggatccaatctcagtttctaattcctcatcccag
attattttgaagtggaaacccccttcggaccccaacggcaacatcactcactacctggtt
ttctgggagaggcaggcggaagacagtgagctgtatgagttggattattgcctcaaaggg
ttgaagctgccctcccggacctggtctccaccgttcgagtctgaagagtcccagaaacac
aaccagagtgactatgaagagtcagccagcgactgctgtgcctgtcccaagaccgactct
cagatcctcaaggagctggaggagtcctcgttccgcaagacattcgaggattacctgcac
aatgtggttttcgtccccagaaaaacctcttcaggccctggcgccgaggaccctaggcca
tcgcggaaacgcagggcccttggcgatgttgggaacgtgacagtggccgtgcccacgatt
ccaggtttccccaatgtctcctcaaccagagtgcccactagcccggcagagcaccggccc
ttcgagaaagtggtaaacaaggagtcgctggtcatttctggcctgcgtcatttcactggc
tatcgcatcgaagtgcaggcttgcaaccaagatgccccagaggaaaggtgtagcgtggca
gcctacgtcagcgccagaactatgcccgaagccaaggctgacgacatcgttggtccagtg
acccatgaaatcttcgagaacaatgtcgtccacttgatgtggcaggagccaaaggaaccc
aatggtctgattgtgctgtacgaagtgagttatcggcgatatggcgatgaggagctgcac
ctttgcgtcntccgtaggcattttgcccgggagcggggctgccggctgcgagggctgccc
ccaggcaactacagctgcgcgtgcggggccacctccctggcgggcaatggctcctggacc
gaagccacccatttctacgtaacagactacttggacgtcccatcaaatattgcaaaaatc
atcattggcccactcatctttgtctttctcgtcagtgttgtgattgggagtatttatcta
ttcctgagaaagaggcagccggacggtccattgggaccgctgtatgcttcttcaaaccct
gagtacctcagtgccagcgatgtgtttccctgctctgtctacgtgcctgacgagtgggag
gtaccccgcgagaagatcaccctcctgcgtgagctgggccagggctccttcggcatggtg
tacgagggcaatgccagggacattgtcaagggcgaggcggagacccacgtggcagtgaag
acagtcaacgagtcagccagcctgcgagagcggatcgagttcctcaatgaggcctctgtc
atgaagggtttcacctgccaccacgtggtccgcctcctgggggtggtgtccaaaggtcag
ccgacgctggtggtgatggagttgatggctcacggggacctgaagagctacctccgttcg
ctgcggccagaggctgagaacaatcccggccgccctccccccaccctgcaagagatgatt
cagatggcagctgagattgcagatgggatggcatacctgaatgccaagaagtttgtgcac
cgggacctcgcagctcgcaactgcatggtggcccacgatttcaccgtcaaaattggagac
tttggaatgaccagagacatctatgaaacggattactaccggaaaggggggaagggcctg
ctccctgtgcggtggatggccccggaatcgctcaaggatggtgtctttaccacgtcttct
gacatgtggtcctttggtgtggtcctttgggaaatcaccagcttggcggagcagccttac
caaggcctgtctaacgagcaggtgttgaaatttgtcatggatggggggtatctggatcaa
cctgacaactgtccagagagagtcaccagcctgatgcaaatgtgctggcagttcaacccc
aagatgcggccgaccttcctggagattgtcgacctgctcaaggacgaccttcaccctagc
tttccggaagtttccttcttccacagcgaggaaaacaaggctcccgagagtgaggagctg
gagatggagtttgaggacatggagaacatccccctggatcagtcctcgcactctcagagg
gacgaggccaggggccgggacggcgggtcctcgctgagcctaaagcggaactacgacgag
cacatcccctacacccacatgaacgggggcaagaagaacgggcggattctgcctctgccc
aggtcgaatccttcctaa
DBGET
integrated database retrieval system
