Loxodonta africana (African savanna elephant): 100668436
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Entry
100668436 CDS
T04351
Symbol
PTK2
Name
(RefSeq) LOW QUALITY PROTEIN: focal adhesion kinase 1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav01522
Endocrine resistance
lav04012
ErbB signaling pathway
lav04062
Chemokine signaling pathway
lav04148
Efferocytosis
lav04151
PI3K-Akt signaling pathway
lav04360
Axon guidance
lav04370
VEGF signaling pathway
lav04510
Focal adhesion
lav04670
Leukocyte transendothelial migration
lav04810
Regulation of actin cytoskeleton
lav04935
Growth hormone synthesis, secretion and action
lav05100
Bacterial invasion of epithelial cells
lav05135
Yersinia infection
lav05146
Amoebiasis
lav05163
Human cytomegalovirus infection
lav05165
Human papillomavirus infection
lav05170
Human immunodeficiency virus 1 infection
lav05200
Pathways in cancer
lav05202
Transcriptional misregulation in cancer
lav05205
Proteoglycans in cancer
lav05208
Chemical carcinogenesis - reactive oxygen species
lav05222
Small cell lung cancer
lav05417
Lipid and atherosclerosis
lav05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100668436 (PTK2)
04370 VEGF signaling pathway
100668436 (PTK2)
04151 PI3K-Akt signaling pathway
100668436 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100668436 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100668436 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100668436 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
100668436 (PTK2)
04062 Chemokine signaling pathway
100668436 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
100668436 (PTK2)
09158 Development and regeneration
04360 Axon guidance
100668436 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100668436 (PTK2)
05202 Transcriptional misregulation in cancer
100668436 (PTK2)
05205 Proteoglycans in cancer
100668436 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
100668436 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
100668436 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
100668436 (PTK2)
05163 Human cytomegalovirus infection
100668436 (PTK2)
05165 Human papillomavirus infection
100668436 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
100668436 (PTK2)
05100 Bacterial invasion of epithelial cells
100668436 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
100668436 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100668436 (PTK2)
05418 Fluid shear stress and atherosclerosis
100668436 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
100668436 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lav01001
]
100668436 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
lav01009
]
100668436 (PTK2)
Enzymes [BR:
lav01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100668436 (PTK2)
Protein kinases [BR:
lav01001
]
Non-receptor tyrosine kinases
FAK family
100668436 (PTK2)
Protein phosphatases and associated proteins [BR:
lav01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
100668436 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
FERM_F2
Kinase-like
Haspin_kinase
NeA_P2
Motif
Other DBs
NCBI-GeneID:
100668436
NCBI-ProteinID:
XP_023401805
LinkDB
All DBs
Position
Unknown
AA seq
1096 aa
AA seq
DB search
MLLEVAGPEALDPAGAVCMARSGCSPFPMCWAEEYDRYLASSKIMAAAYLDPNLNHTPNS
STKTHLGTGMERSPGTMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHK
VKHVACYGFRLSHLLSEEVHWLHLDMGVSNVREKYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEV
LEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQTIQYSNSEDKDRKGML
QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIPKL
ANSEKQGVRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDV
HQGVYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVW
IIMELCTLGELRSFLQMRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSS
PDCVKLGDFGLSRCMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEIL
MHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQL
STILEEEKVQQEERMRMESRRQVTVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHV
VQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEVSMWQPNVEDSAALDM
RGIGQVLPAHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGGLQGPTG
NQHIYQPVGKPDPAAPPKKPPRPGAPSHLGSLASLSSPGDSYNEGVKLQPQEISPPPTAN
LDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPVLP
ASTHREIEMAQKLLNSDLGGLINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLD
VIDQARLKMLAQTRPH
NT seq
3291 nt
NT seq
+upstream
nt +downstream
nt
atgttgttggaagtggcgggccccgaggccctggatccagcaggtgccgtctgtatggcg
agaagcggctgtagtccatttccaatgtgctgggctgaagaatatgacagatacctagca
tctagcaaaataatggcagctgcttaccttgacccaaacttgaatcacacgccaaattcg
agtactaagactcacctgggtactggtatggaacgttctcctgggacaatggagcgagta
ttaaaggtctttcattattttgaaagcaatagtgaaccaaccacatgggccagtattatc
agacatggagatgctactgatgtcaggggcatcattcagaagatagtggacagtcacaaa
gtaaagcacgtggcctgctatggattccgcctcagtcacctgctgtcggaggaggttcac
tggctccatttggatatgggtgtttccaatgtgagggagaagtacgaacttgcacacccc
ccagaggagtggaaatatgaattgagaattcgttatttgccaaaaggatttctaaaccag
tttactgaagataagccaactttgaatttcttctatcaacaggtgaagagcgattatatg
ttagagatagctgatcaagtggaccaggaaattgctttgaagttgggctgtctagaaata
cggcgctcatactgggagatgcggggcaacgcgctggaaaagaagtctaactatgaagta
ttagaaaaagatgttggtttaaagcgatttttccctaagagtttactggattctgtcaag
gccaaaacactaagaaaactgatccaacagacgtttagacaatttgccaaccttaataga
gaagaaagtattctgaaattctttgagattctctcccctgtgtacagatttgataaagaa
tgcttcaaatgtgctcttggttcaagctggattatttcagtggaactggcaatcggccca
gaagaaggcatcagttacctaacggacaagggctgcaaccctacacatctggccgacttt
aaccaagtgcagaccatccagtattcaaacagcgaagacaaggacagaaaaggaatgcta
cagctaaaaatagcaggcgcacccgagcctctgacagtgacggccccatccttaaccatt
gcagagaatatggctgacttgatcgatggctactgccggctggtgaatggagccacgcag
tctttcatcatcagaccccagaaagaaggtgaacgggctttaccatcaataccaaagctc
gccaacagcgagaagcagggcgtgcggacccacgctgtctccgtgtcagagacagacgac
tatgctgagattatagatgaagaagatacgtacaccatgccctccaccagggattatgag
attcaaagagaaagaatagaacttggacgatgtattggagaaggccagttcggagatgta
catcaaggagtgtatatgagtccggagaatccagctttggcggttgcaattaaaacgtgt
aaaaactgtacttcggacagcgtgagagagaaattccttcaagaagccttaacaatgcgt
cagtttgaccatcctcacatcgtgaagctgattggtgtcatcacggagaatcccgtctgg
ataatcatggagctgtgcacgcttggggagctgaggtcatttttgcaaatgaggaaatac
agtttggatctggcgtctttgattctgtatgcctaccaactgagtacagctcttgcatat
ctagagagcaaaagatttgtacacagggacattgctgctcggaacgttctggtgtcttcg
cctgattgtgtaaaactaggagactttgggttatcccggtgcatggaagacagcacctac
tacaaagcttccaaaggaaaattgccgattaagtggatggctccagagtccatcaatttt
cgacgttttacctcagctagtgatgtgtggatgtttggtgtgtgtatgtgggagattttg
atgcatggtgtgaagccttttcaaggagtgaagaacaatgatgtgatcggtcggattgaa
aatggggagagattaccaatgcctccaaattgtcctcctaccctctacagccttatgacg
aagtgctgggcctatgaccccagcaggcggcccaggtttactgaacttaaagcgcagctc
agcacaatcctggaggaagagaaggttcagcaagaagagcgcatgagaatggagtccaga
agacaggtcacagtgtcctgggactctggagggtccgatgaagcacctcccaagcccagc
agacctggttatcccagtccgaggtcaagtgaaggattttatcccagcccacagcacgtg
gtacaaaccaatcattaccaggtctctggctaccctggctcccatggaatcacagccatg
gctggcagcatctacccgggccaggcctctcttctggaccaaacagactcgtggaatcac
agacctcaggaggtatcaatgtggcagcccaacgtggaggactctgcagcattggacatg
cgaggaattgggcaggtactgccagcccacctgatggaagagcggctgatccgacagcaa
caggagatggaagaagaccagcgctggctggagaaagaggagagattcctgaagccggac
gtgaggctctctcggggcagcatcgacagggaggacggaggtctccaaggcccgactgga
aaccaacacatatatcagcctgtgggtaagccagatcctgcagctccaccaaagaaaccc
ccgcgccctggagcccccagccacctgggcagccttgccagcctcagcagccctggggac
agctacaacgagggcgtcaagctccagccccaggagatcagccctccgcccacggccaat
ctcgaccgctccaacgacaaggtgtacgagaacgtcactggcctagtgaaagctgtcatt
gagatgtccagtaaaatccagccggccccgccagaggagtacgtgcctatggtgaaggaa
gtcggcttggccctgaggacattactggcgactgtggatgagaccattcccgtcctgcca
gccagcacacaccgagagattgagatggcccagaagctgctgaactccgacctagggggg
ctcatcaacaagatgaagctggcccagcagtacgtcatgaccagcctccagcaggagtac
aagaagcaaatgctgaccgctgcgcatgccctggccgtggatgccaaaaacctgctggac
gtcattgaccaagcaagactgaaaatgctggcgcagacgagaccgcactga
DBGET
integrated database retrieval system
