Loxodonta africana (African savanna elephant): 100674054
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Entry
100674054 CDS
T04351
Symbol
FGFR3
Name
(RefSeq) fibroblast growth factor receptor 3 isoform X1
KO
K05094
fibroblast growth factor receptor 3 [EC:
2.7.10.1
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav01521
EGFR tyrosine kinase inhibitor resistance
lav04010
MAPK signaling pathway
lav04014
Ras signaling pathway
lav04015
Rap1 signaling pathway
lav04020
Calcium signaling pathway
lav04144
Endocytosis
lav04151
PI3K-Akt signaling pathway
lav04550
Signaling pathways regulating pluripotency of stem cells
lav04810
Regulation of actin cytoskeleton
lav05200
Pathways in cancer
lav05206
MicroRNAs in cancer
lav05219
Bladder cancer
lav05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100674054 (FGFR3)
04014 Ras signaling pathway
100674054 (FGFR3)
04015 Rap1 signaling pathway
100674054 (FGFR3)
04020 Calcium signaling pathway
100674054 (FGFR3)
04151 PI3K-Akt signaling pathway
100674054 (FGFR3)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100674054 (FGFR3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
100674054 (FGFR3)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100674054 (FGFR3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100674054 (FGFR3)
05206 MicroRNAs in cancer
100674054 (FGFR3)
05230 Central carbon metabolism in cancer
100674054 (FGFR3)
09162 Cancer: specific types
05219 Bladder cancer
100674054 (FGFR3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100674054 (FGFR3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lav01001
]
100674054 (FGFR3)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
lav04090
]
100674054 (FGFR3)
Enzymes [BR:
lav01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100674054 (FGFR3)
Protein kinases [BR:
lav01001
]
Receptor tyrosine kinases (RTK)
FGFR family [OT]
100674054 (FGFR3)
CD molecules [BR:
lav04090
]
Proteins
100674054 (FGFR3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
I-set
Ig_3
ig
Ig_2
V-set
FGFR3_TM
C2-set_2
ABC1
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
100674054
NCBI-ProteinID:
XP_023405471
LinkDB
All DBs
Position
Unknown
AA seq
808 aa
AA seq
DB search
MGAPACALALCVAVAVVAGAASGPPGTELRVVRRAAEALEPEPGQKEQLVFGSGDTMELT
CHPPMGSTPGPTIWVKDGLGLVPSDRILVGLQRLQVLNASHEDAGAYSCRQRLTQRILCR
FSVRVTDAPSSGDDEDSEDEAEDTGVPVGAPYWTRPERMDKKLLAVPAANTVRFRCPAAG
NPTPSISWLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQT
YTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGP
DGTPYVTVLKSWISESAEADARLRLANVSERDGGEYLCRATNFIGVAEKAFWLRVHGPPA
AEEELAEADEASSVYAGVLSYGAGFFFFIMVVVAVTLCRLHSPTKKGLGSPAVHKVSRFP
LKRQVSLESNSSMNSNTPLVRMARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPL
GEGCFGQVVMAEAIGIDKERAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNI
INLLGACTQGGPLYVLVEYAAKGNLREYLRARRPPGMDYSFDTCKLPEEQLTFKDLVSCA
YQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPV
KWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPAN
CTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSVPFEQYSPGGQDTP
SSGSSGDDSVFAHDLLLPAPPSSGALRT
NT seq
2427 nt
NT seq
+upstream
nt +downstream
nt
atgggcgccccggcctgcgccctcgctctctgcgtggccgtggccgtcgtggccggcgct
gcctcggggcccccgggcacagagctacgcgtcgtgaggagagcggcagaggccctggag
cctgagcctggccagaaagagcagctggtctttggcagtggggacaccatggagctgacc
tgccacccacccatgggcagtaccccaggacccaccatctgggtgaaggacggcttgggg
ctagtgccctcggaccgcatcctggtggggctgcagaggctacaggtgctcaacgcctcc
cacgaggacgctggcgcgtacagctgccgccagcggctcacccagcgcatcctgtgccgc
ttcagcgtgcgggtgacagatgctccgtcctcgggagatgacgaagacagtgaggacgag
gctgaggatacaggtgtgcctgtaggagccccttattggacacggcctgagcgcatggac
aaaaagctcttggccgtgccagcggccaacaccgtccgcttccgctgcccggccgctggc
aaccccacaccctccatatcgtggctcaagaacggcaaggaattccgtggcgagcaccgc
attgggggcatcaagctgcggcaccagcagtggagtctggtcatggagagtgtggtgccc
tccgaccggggcaactatacgtgtgtggtggagaacaagttcggcagcatccggcagacg
tacacgttggatgtgctcgagcggtccccgcaccggcccatcctgcaggcagggctgcca
gccaaccagacggcagtgctgggcagcgacgtggagttccactgcaaggtatacagcgac
gcccagccccacatccagtggctcaaacacgtggaggtgaacggcagcaaggtgggcccc
gacggcacaccctacgtcactgtgctcaagtcctggatcagtgagagtgcggaggctgac
gcgcgcctccgcctggccaatgtgtccgagcgggacgggggcgagtacctctgtcgagcc
accaatttcataggcgtggccgagaaggccttttggctgcgtgttcacgggcccccagca
gctgaggaggagctggcggaggcggacgaggccagtagcgtgtacgcaggcgttctcagc
tacggggcaggcttcttcttcttcatcatggtggtggtggccgtgaccctgtgccggctg
cacagcccgaccaagaagggcctgggctctcccgccgtgcacaaggtctcccgcttcccg
ctcaagcgacaggtgtccctggagtccaactcgtccatgaattccaacacgccactggtg
cgcatggccaggctgtcctcgggggagggccccacgctggccaacgtctctgagctcgag
ctgcctgccgaccccaagtgggagctgtcccgcgcccggctgaccctgggcaagcccctg
ggggagggctgcttcggccaggtggtcatggcagaggctatcggcatcgacaaagagcgg
gctgccaagcctgtcactgtggctgtgaagatgctgaaagacgatgccacggacaaggac
ctctcggacctggtgtcagagatggagatgatgaagatgattggcaagcacaagaacatc
atcaacctgctgggggcctgcacgcagggcgggcccctgtatgtgctggtggagtacgcg
gccaagggcaacctgcgggagtaccttcgggcgcggaggcccccgggcatggactactcc
tttgacacctgcaagttgcctgaggagcagctcaccttcaaggacctcgtgtcctgtgcc
taccaggtggcacggggcatggagtatctggcctcccagaagtgcatccacagggatctg
gccgcccgcaatgtgctggtgacagaggacaacgtgatgaagatagctgactttggcctg
gcccgggatgtgcacaacctggactactacaagaagaccaccaacggccggctgcccgtg
aagtggatggcacccgaggctctgtttgaccgagtctacacccaccagagtgacgtctgg
tcctttggtgtcctgctctgggaaattttcacgctggggggctcaccataccccggcatt
cccgtggaggagctcttcaagctgctcaaggaaggccaccgcatggacaagccagccaac
tgcacacacgacctgtacatgatcatgcgagagtgctggcatgctgtgccctcccagcgg
cccaccttcaagcagctggtggaggacctggaccgtgtgctcactgtgacgtccactgac
gagtacctggacctgtcagtgccatttgagcagtactcgcctggtggccaggacacaccc
agctccggctcctcgggcgatgactctgtgtttgcccacgaccttctgctgcctgccccc
cccagcagcggggctctgcggacgtga
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