Loxodonta africana (African savanna elephant): 100674589
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Entry
100674589 CDS
T04351
Symbol
ARHGEF1
Name
(RefSeq) rho guanine nucleotide exchange factor 1 isoform X2
KO
K12330
Rho guanine nucleotide exchange factor 1
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav04270
Vascular smooth muscle contraction
lav04611
Platelet activation
lav04810
Regulation of actin cytoskeleton
lav04928
Parathyroid hormone synthesis, secretion and action
lav05135
Yersinia infection
lav05163
Human cytomegalovirus infection
lav05200
Pathways in cancer
lav05205
Proteoglycans in cancer
lav05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
100674589 (ARHGEF1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100674589 (ARHGEF1)
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
100674589 (ARHGEF1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
100674589 (ARHGEF1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100674589 (ARHGEF1)
05205 Proteoglycans in cancer
100674589 (ARHGEF1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
100674589 (ARHGEF1)
09171 Infectious disease: bacterial
05135 Yersinia infection
100674589 (ARHGEF1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100674589 (ARHGEF1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
lav04131
]
100674589 (ARHGEF1)
Membrane trafficking [BR:
lav04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
100674589 (ARHGEF1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PH_13
AbiJ_NTD3
SOS1_NGEF_PH
Focadhesin
SET_assoc
Motif
Other DBs
NCBI-GeneID:
100674589
NCBI-ProteinID:
XP_010600810
LinkDB
All DBs
Position
Unknown
AA seq
912 aa
AA seq
DB search
MQAAEEMARGAAPGPPRPGLVPISIIGAEDEDFENELETNAEEQNSQFQSLEQVKRRPVH
LIALLQHVALQFEPAPLLCCLHADMLSTLGPKEFKKAFIDFYHSFLDKTAVLRVSVPANV
AFELDRTRPDLISEDIQRRFVQEVVQSQQAAISRQLEDFRSKRLMGMTPWEQELAHLEAW
AGRDRTTYEARERLTAERLLTHLEEMQPTISTDEEKSAAVVNAISVYMRHLGVRTKSGDK
KSGRNFFRKKNRRPDEPPKTKKGLSSILDAARWNRGEPQVPDFRHLKIEAEADKQGSTER
KGGLAVPSRDRNVGVPGQDTLGVSLHPLSGDSPDREPGVDPPLELGDLPLQGPTNLEPPA
APESTEEGADTESPEPGDEGEPGRLGLELEPEEPPGWRELVPPDTLHSLPKSQVKRQEVI
SELLVTEAAHVRMLRVLHDLFYQPMAEGGFFPQDELQNIFPSLDELIEVHSLFLDSLMKR
RQDSGYLIEEIGDVLLARFDGAEGTWFQKISSRFCSRQSFALEQLKAKQRKDPRFCAFVQ
DAESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQNTEEPAERKKVERAAECCREILHH
VNQAVRDMEDLLRLKDYQRRLDLSHLRQSSDPMLSEFKNLDITKKKLVHEGPLTWRVTKD
KAVEVHVLLLDDLLLLLQRQDERLLLKSHSRTLTPTPDGKTMLRPVLRLTSAMTREVATD
HKAFYVIFTWDQEAQIYELVAQTVSERKNWCALITETAGSLKVPAPASRPKPPRTSPSST
REPLLSSSENSNGGREMPPPDGRMERILSDLLPFCRPGPEGQLAATALQKVLSLKQLLLP
VKEDSGAGPPREGDGVPGGGPLSLSQTQKVQEKLLSLEETVKRLEEMEEEFCRLRLLLSQ
LGGNTAPQPGCT
NT seq
2739 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcagcggaagaaatggcccgaggggcggccccagggcccccccggcctggcctg
gtgcccatcagcatcatcggggctgaggacgaagattttgagaatgagctggagacgaat
gcagaggagcagaacagccagttccagagcctggagcaggtgaagcggcgcccagtccac
ctcatagccctcctgcagcacgtggccctgcagttcgagccagcacccctgctctgctgc
ctccacgcggacatgctgagcaccctgggccccaaggagttcaagaaggcctttattgac
ttctaccacagcttcctggataagacagcggttctgcgggtgtcagtgcctgccaacgtc
gcctttgaacttgaccgtacgcggcctgacctcatctctgaggacatccagcggcggttc
gtgcaggaggtggtgcagagccagcaggcggccatcagccggcagctggaggacttccgc
tctaagcggctcatgggcatgacgccctgggagcaggagctggcccatctggaggcctgg
gctggacgggaccgcaccacctatgaggcccgggagcggctcacggccgagcggctactg
acccaccttgaggagatgcaacccaccatctctaccgatgaagaaaagagtgctgctgtg
gtcaacgccatcagcgtgtacatgcgccaccttggggtgcgaaccaagagcggggacaag
aaatcgggaaggaacttcttccggaaaaagaaccggcggccagatgagcctcccaagacc
aagaaaggactgagcagcatcctggatgccgcccgctggaaccggggagagccccaggtg
ccagattttcgacacctcaaaatcgaggctgaagctgataagcaaggctctacagaacgg
aagggaggcctggcagtgccttctcgagaccgaaatgttggggttcctgggcaagacacc
ctcggagtttctctgcaccctctgtctggggacagcccagaccgagaaccaggtgttgac
cccccactggagctgggggacctgcccctgcagggcccaacaaacctggagcccccggca
gccccagagagcactgaggagggtgctgacacagagagccctgagcctggagatgagggg
gagccagggcggttgggactagagctggaaccagaggagccccctggctggcgggaactg
gtcccgccggacaccctgcacagcctgcccaagagccaggtgaagcggcaggaagtcatt
agcgagctgctggtgacggaggcggcacacgtgcgcatgcttcgggtgctgcatgacctc
ttctaccagcccatggcggagggtggcttcttcccgcaggatgagctgcagaacatcttt
cccagcctggacgagctcatcgaggtgcattccttattccttgatagcctgatgaagcgg
agacaggacagtggctacctcattgaggagattggggatgtgctgctggcccggtttgat
ggtgctgagggcacgtggttccagaaaatctcctcccgcttctgcagccggcagtctttt
gccttagagcagctcaaagccaaacagcgcaaggatcctcgattctgtgcctttgtgcag
gatgccgagagccgtccacggtgtcgccgcttacagctgaaggacatgatccccactgag
atgcagcgcctgaccaagtaccccctgctcctccaaagcatcggacagaatacagaagag
cctgcggaacggaagaaagtggagcgggcggccgagtgctgccgggaaattctgcaccac
gtcaaccaggccgtgcgcgacatggaggacctgctgaggctcaaggattatcagcggcgc
ctggacttgtcccaccttcgtcagagcagcgaccccatgctgagcgagttcaagaacctg
gacatcaccaagaaaaagttggttcatgagggcccgctgacatggcgagtgacgaaggac
aaggctgtggaggttcatgtgctactgctggatgacctgctgctgctgctgcagcgccag
gatgagcggctgctgctcaaatcgcacagccgcacgctgacgcccacaccagatggcaag
accatgctgcggcctgtgctgcggctcacctccgccatgacccgagaggtggccactgat
cacaaagccttctacgtcattttcacttgggaccaggaggcccagatatatgagctggtg
gcacagacagtgtctgagaggaagaactggtgtgccctcatcacggagaccgctggatcc
ctgaaagtccccgcccccgcctcccgcccaaaacccccccggaccagcccaagcagcact
cgagaacccctgctcagcagctctgaaaacagcaacggtggcagagagatgcctccacct
gatggccgtatggagagaatcctcagtgacctcctgcccttctgcagaccaggccctgag
ggccagctcgctgccaccgcccttcagaaagtgctgtccttgaagcagctcctgttgcct
gtgaaggaagacagcggggcagggcctccccgagaaggggatggggtcccgggtggtggt
cccctgagcctatcgcagacccagaaggtccaggagaagctgctcagtctggaggagacc
gtgaagcggctggaggagatggaggaggaattttgccgccttcgactcctcctatctcag
ctgggtgggaacactgctccccagcctggctgcacctga
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