Legionella cardiaca: PXX05_04755
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Entry
PXX05_04755 CDS
T08869
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
lcad
Legionella cardiaca
Pathway
lcad00010
Glycolysis / Gluconeogenesis
lcad00020
Citrate cycle (TCA cycle)
lcad00620
Pyruvate metabolism
lcad00785
Lipoic acid metabolism
lcad01100
Metabolic pathways
lcad01110
Biosynthesis of secondary metabolites
lcad01120
Microbial metabolism in diverse environments
lcad01200
Carbon metabolism
lcad01210
2-Oxocarboxylic acid metabolism
Module
lcad_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
lcad00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
PXX05_04755 (aceE)
00020 Citrate cycle (TCA cycle)
PXX05_04755 (aceE)
00620 Pyruvate metabolism
PXX05_04755 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
PXX05_04755 (aceE)
Enzymes [BR:
lcad01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
PXX05_04755 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
WED44100
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Position
1085270..1087933
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AA seq
887 aa
AA seq
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MLYENSNDIDPIETREWLDALQAVLSTDGGQRAAFLLQELINKANAEGVKLKSAINTPYR
NTIKPHEEKLLPPDEGLGKRISALIRWNAVAMVLRAGKYAPELGGHIASYASSSTLYETG
FNYFFKGPNGDHGGDLLYIQGHSSPGIYARAFLEGRLSEHQLNKFRQEVEVNGLSSYPHP
WLMGDFWQFPTVSMGLGPLQAIYQARFLKYLENRGLIKAEGRKVWAFLGDGEMDEPESVG
ALSIAAREKLDNLIFVVNCNLQRLDGPVRGNGKIIQELEGLFRGAGWNVIKVIWGGRWDP
LFARDDKGIMQKRMEECVDGDYQAYKANDGAYVREHFFGQYPELKKMVENMSDDEIWRLN
RGGHDAQKVYAAYAQAVEHRGSPTVILAKTIKGYGMGAAGEGQNITHQQKKMTIEQLRAF
RDRFSIPISDDKITEIPFYRPDESSPEIQYLRKQREALGGYLPARSTAFEPLKVPELSAF
STITQSTGDREISTTMAFVRLLSVLLKDKELGKRIVPIVPDECRTFGMEGLFRQIGIYSP
VGQLYTPVDHEQVMYYREAKDGQILEEGINEAGAFCSWIAAATSYSSNKLAMIPFYIYYS
MFGFQRIGDLAWAAGDMQARGFLLGGTAGRTTLAGEGLQHQDGHSHIMASTIPNCIAYDP
TYAYELAVIIQHGLYRMYEKQDNVFYYITVMNENYTHPDMPAGVEEGIIKGMYLLQETKK
PSKKHVQLMGCGTILREVIAAAKMLSDDFGVTSDIWSVTSFNELRRDGLAVERHNRMHPE
DKPKQSYVTKQLADRKGPVIAATDYMRLYADQIRPFVSAPFITLGTDGYGRSDTRQRLRH
FFEVDAKFIAIAALDALAQQGTLPKSTVVDAMKRYGIDSEKLDPVTH
NT seq
2664 nt
NT seq
+upstream
nt +downstream
nt
atgttatacgaaaatagtaatgatattgacccaattgaaacacgtgaatggctggatgcc
ttgcaagcagtactctccactgatggaggccagcgtgctgcatttcttctacaagagctt
attaataaggctaatgccgaaggggtaaaactaaagagtgcaattaataccccttatcgt
aatacgattaaacctcatgaagaaaaattgttgccgcctgatgaaggattagggaagcga
ataagtgcattaattcgttggaatgctgttgcgatggtattacgtgcgggtaaatatgct
cctgagttgggagggcatattgcctcttacgcttcatcatctactttatacgaaacggga
tttaattatttcttcaaaggccccaacggagaccatggtggtgatttactctatatccag
ggacattcctcaccaggaatctatgcgcgagcctttttagaaggacgattgtctgagcat
caattaaacaaatttagacaagaagttgaagtcaatggtttatcatcttatccccatcct
tggttaatgggtgatttttggcaatttccaacagtgtctatgggattaggtcctctacaa
gcaatttatcaggctcgtttccttaaatatctagagaatcgtggtttaattaaagcagaa
ggccgtaaagtgtgggcttttcttggcgacggtgaaatggatgagcctgagtctgtaggc
gctctgtctattgctgctcgtgaaaagttagataatttgatttttgtcgtaaactgcaat
ctacagcgtcttgatggtcctgtaagagggaatggcaaaattattcaggaattagaaggc
ttatttcgcggtgcaggatggaatgtgattaaagttatttggggcggccgatgggatcca
ttatttgcccgagatgataaaggtattatgcaaaagcgcatggaagaatgcgttgatggt
gattatcaagcctataaggctaatgatggtgcttatgtccgtgagcatttttttggtcaa
taccctgaattgaaaaaaatggtagagaatatgtcagatgatgaaatctggcgtttaaat
cgtggtggtcatgatgctcaaaaagtctatgctgcctatgcacaagctgtagaacatcgt
ggtagtccaactgtaattcttgctaaaaccattaaaggttatggtatgggggctgctggt
gaaggtcaaaacattactcatcagcaaaaaaaaatgaccatcgagcagctacgtgctttt
agggatcgttttagtattccaattagcgatgacaaaattacagagattccattctatcgt
ccagacgagagtagccctgaaatccagtatttgcgtaagcaaagagaagctttaggtgga
tatttaccggcgcgaagtaccgcttttgaacctttaaaagtgcctgagttatcggctttt
tcgacaatcactcagagtaccggcgatcgtgaaatttctacaaccatggcatttgtgcgt
ctgttgtccgttttacttaaagataaagaattaggtaagcggattgtgccaattgttcct
gatgaatgccgtacctttggaatggaaggcttattccgtcaaattggaatttattcacca
gtagggcagttatatacgccagtggatcacgagcaagtgatgtattaccgtgaagcaaaa
gatgggcaaattcttgaggaaggcattaatgaagcaggggcattttgttcctggattgct
gctgcaacctcatacagctctaataaattggcaatgattccattctacatttattactcc
atgtttggtttccaacgtattggtgatttagcatgggctgcaggggatatgcaggctcga
ggattcttattaggtggtacagctggtagaacaactctggcgggggaaggattgcagcat
caagacggtcatagtcatattatggcttctaccatacccaattgcattgcttatgatcct
acttatgcctatgagttggctgtaatcattcagcatggtttgtatcgtatgtatgaaaag
caagataacgttttttactacattacggttatgaatgaaaactatactcatccagacatg
ccggccggtgtagaagaaggaattattaaagggatgtacctgctgcaagaaactaaaaaa
cccagtaaaaaacatgtccagttaatgggatgtggtactattttacgtgaagtaattgca
gcagcgaaaatgcttagtgatgattttggagtaacttctgatatatggagtgtcacaagc
tttaatgaattaagacgagacgggttagctgttgagcgtcataatcgcatgcatcctgaa
gataagcccaagcaaagttatgtaactaagcaattagctgatcgtaaagggcccgtgatt
gctgcaacagattatatgcgcttatatgccgatcaaatcaggccttttgtttccgcacca
tttattaccctgggtacagatggttatggacgcagtgacacacgtcaacgcttacgtcat
ttcttcgaagttgatgctaaatttattgcaatagctgcattagatgctttagctcaacag
ggtacattacctaaatcaacggtagttgatgcgatgaaacgttatggcattgatagtgag
aagcttgatccagtaactcactga
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