KEGG   PATHWAY: lcat00531
Entry
lcat00531                   Pathway                                
Name
Glycosaminoglycan degradation - Lemur catta (Ring-tailed lemur)
Class
Metabolism; Glycan biosynthesis and metabolism
Pathway map
lcat00531  Glycosaminoglycan degradation
lcat00531

Module
lcat_M00077  Chondroitin sulfate degradation [PATH:lcat00531]
lcat_M00079  Keratan sulfate degradation [PATH:lcat00531]
Other DBs
GO: 0006027
Organism
Lemur catta (Ring-tailed lemur) [GN:lcat]
Gene
123620504  SGSH; N-sulphoglucosamine sulphohydrolase isoform X1 [KO:K01565] [EC:3.10.1.1]
123621189  NAGLU; alpha-N-acetylglucosaminidase [KO:K01205] [EC:3.2.1.50]
123622158  IDUA; alpha-L-iduronidase isoform X1 [KO:K01217] [EC:3.2.1.76]
123623243  HYAL2; hyaluronidase-2 [KO:K01197] [EC:3.2.1.35]
123623244  HYAL1; hyaluronidase-1 isoform X1 [KO:K01197] [EC:3.2.1.35]
123623245  HYAL3; hyaluronidase-3 isoform X1 [KO:K01197] [EC:3.2.1.35]
123623970  HEXA; beta-hexosaminidase subunit alpha [KO:K12373] [EC:3.2.1.52]
123625385  GALNS; LOW QUALITY PROTEIN: N-acetylgalactosamine-6-sulfatase [KO:K01132] [EC:3.1.6.4]
123626593  HGSNAT; heparan-alpha-glucosaminide N-acetyltransferase isoform X1 [KO:K10532] [EC:2.3.1.78]
123627236  HPSE; heparanase [KO:K07964] [EC:3.2.1.166]
123627722  GLB1; beta-galactosidase [KO:K12309] [EC:3.2.1.23]
123632661  GUSB; LOW QUALITY PROTEIN: beta-glucuronidase [KO:K01195] [EC:3.2.1.31]
123639556  GNS; N-acetylglucosamine-6-sulfatase [KO:K01137] [EC:3.1.6.14]
123646932  HYAL4; hyaluronidase-4 [KO:K01197] [EC:3.2.1.35]
123646963  [KO:K01197] [EC:3.2.1.35]
123646964  [KO:K01197] [EC:3.2.1.35]
123646965  [KO:K01197] [EC:3.2.1.35]
123647238  [KO:K01197] [EC:3.2.1.35]
123647395  [KO:K01197] [EC:3.2.1.35]
123648425  ARSB; arylsulfatase B isoform X1 [KO:K01135] [EC:3.1.6.12]
123648546  HEXB; beta-hexosaminidase subunit beta [KO:K12373] [EC:3.2.1.52]
Compound
C00426  Dermatan sulfate
C00573  Keratan sulfate
C00634  Chondroitin 4-sulfate
C00925  Heparan sulfate
G00526  
G00711  
G00872  DWA-2
G01391  
G01945  
G01977  
G02632  
G09660  
G10008  
G10505  Hyaluronic acid
G12336  
G13034  
G13035  
G13036  
G13037  
G13038  
G13039  
G13040  
G13041  
G13042  
G13043  
G13073  
G13074  
Reference
PMID:27570
  Authors
Greiling H, Stuhlsatz HW, Cantz M, Gehler J
  Title
Increased urinary excretion of keratan sulfate in fucosidosis.
  Journal
J Clin Chem Clin Biochem 16:329-34 (1978)
DOI:10.1515/cclm.1978.16.6.329
Reference
PMID:3161730
  Authors
Fuchs W, Beck M, Kresse H
  Title
Intralysosomal formation and metabolic fate of N-acetylglucosamine 6-sulfate from keratan sulfate.
  Journal
Eur J Biochem 151:551-6 (1985)
DOI:10.1111/j.1432-1033.1985.tb09138.x
Related
pathway
lcat00532  Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
lcat00533  Glycosaminoglycan biosynthesis - keratan sulfate
lcat00534  Glycosaminoglycan biosynthesis - heparan sulfate / heparin
KO pathway
ko00531   

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