Lemur catta (Ring-tailed lemur): 123630753
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Entry
123630753 CDS
T08326
Symbol
BACE2
Name
(RefSeq) beta-secretase 2
KO
K07747
beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:
3.4.23.45
]
Organism
lcat
Lemur catta (Ring-tailed lemur)
Pathway
lcat05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
lcat00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
123630753 (BACE2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
lcat01002
]
123630753 (BACE2)
Enzymes [BR:
lcat01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.45 memapsin 1
123630753 (BACE2)
Peptidases and inhibitors [BR:
lcat01002
]
Aspartic peptidases
Family A1: pepsin family
123630753 (BACE2)
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Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
123630753
NCBI-ProteinID:
XP_045396653
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Position
1:282096431..282175960
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AA seq
514 aa
AA seq
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MGALARALLLPLLAQWLLRAAPAPAPAPFTLPLRVAGAASRGASLTPGPGTPAAPGADGL
ALALEPAGGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGAPHS
YIDGYFDAARSSTYRPKGFDVTVKYTQGSWTGSVGEDIVTIPKGFNGSFLVNIATIFESE
NFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGAGT
NGGSLVLGGVEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDS
GTTLLRLPQKVFDAVVEAVARTSLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRD
ENSSRSFRITILPQLYIQPMMGTGLNYECYRFGISPSTNALVIGATVMEGFYVIFDRARR
RVGFAASPCAEIAGAPVSEISGPFSTDDIASNCVPAQSLNEPVLWIVSYALMSVCGIILL
MLILLLLLPCRCPRRPRDPEAVNDESSLVRHRWK
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
atgggcgcgctggcccgggcgctgctgctgccgctgctggcccagtggctcctgcgcgcc
gccccggcgccggcccccgcgcccttcacgctgcccctccgggtggctggagccgcgagc
cgcggggcttcgctcacccccgggcccgggacccccgccgcgcccggcgccgacggcctg
gctctcgccctggagcccgccgggggcgccgccaacttcttggccatggtggacaacctg
cagggggactccggccgcggctactacctggagatgctgatcgggacccctccgcagaag
ctacagattcttgtcgacaccggaagcagcaacttcgccgtggcaggtgccccgcattcc
tacatagatggctactttgacgcggcacggtctagcacctaccgccccaagggctttgat
gtcaccgtgaagtacacgcaagggagctggaccggctcggtcggggaggacatcgtcacc
atcccaaaaggcttcaatggctcttttcttgtcaacattgccaccatttttgagtcagag
aatttctttctgcctgggattaagtggaacggaatactcggccttgcgtatgccaccctg
gccaagccatcaagttctctggagactttctttgactccctcgtgacgcaagcaaacatt
cccaacgttttctccatgcagatgtgcggggccgggttgcccgtagctggagccggtacc
aacggaggtagtcttgtcctgggtggggttgaacccagtttgtataaaggagacatctgg
tatacccccattaaggaggagtggtattatcagatagaaattctgaagctggaaatcgga
ggccaaagccttaatctggactgcagagagtataacgcggacaaggccattgtggacagc
ggcaccacgctgctgcgcctgccccagaaggtgttcgacgcggtggtggaagccgtggcc
cgcacgtctctgattccagaattctctgacggcttctggacgggatcccagctggcgtgc
tggacgaattccgaaacaccatggtcttacttccccaagatctccatctacctgcgggac
gagaactccagcagatcattccgtataactatcctgcctcagctgtacatccagcccatg
atgggcaccggcctgaattatgaatgttaccggttcggcatctccccttccacgaacgcg
ctggtgatcggggccaccgtgatggagggcttctacgtcatcttcgacagagcgaggagg
agggtgggcttcgcggcgagtccctgtgcagaaattgcaggtgctccggtgtctgaaatt
tctgggcctttctcgacagatgacatagccagcaactgtgtccccgcccagtctctgaac
gagcccgttctgtggatcgtctcctacgccctcatgagcgtgtgcggcatcatcctgctc
atgctcatcctcctgctgctgcttccctgccggtgtccccggcgcccccgcgaccctgag
gccgtcaacgatgagtcctctctcgtcagacaccgctggaaatga
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