Lemur catta (Ring-tailed lemur): 123637096 Help Entry 123637096         CDS       T08326                                  Symbol HK2 Name (RefSeq) hexokinase-2   KO K00844   hexokinase [EC:2.7.1.1] Organism lcat  Lemur catta (Ring-tailed lemur) Pathway lcat00010   Glycolysis / Gluconeogenesis lcat00051   Fructose and mannose metabolism lcat00052   Galactose metabolism lcat00500   Starch and sucrose metabolism lcat00520   Amino sugar and nucleotide sugar metabolism lcat00524   Neomycin, kanamycin and gentamicin biosynthesis lcat01100   Metabolic pathways lcat01200   Carbon metabolism lcat01250   Biosynthesis of nucleotide sugars lcat04066   HIF-1 signaling pathway lcat04910   Insulin signaling pathway lcat04930   Type II diabetes mellitus lcat04973   Carbohydrate digestion and absorption lcat05230   Central carbon metabolism in cancer Module lcat_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate lcat_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc lcat_M01015   GDP-Man biosynthesis, Man => GDP-Man Brite KEGG Orthology (KO) [BR:lcat00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     123637096 (HK2)    00051 Fructose and mannose metabolism     123637096 (HK2)    00052 Galactose metabolism     123637096 (HK2)    00500 Starch and sucrose metabolism     123637096 (HK2)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     123637096 (HK2)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     123637096 (HK2)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     123637096 (HK2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     123637096 (HK2)   09154 Digestive system    04973 Carbohydrate digestion and absorption     123637096 (HK2)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     123637096 (HK2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     123637096 (HK2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:lcat04131]     123637096 (HK2) Enzymes [BR:lcat01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      123637096 (HK2) Membrane trafficking [BR:lcat04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     123637096 (HK2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 FGGY_N Motif Other DBs NCBI-GeneID:  123637096 NCBI-ProteinID:  XP_045405893 LinkDB All DBs Position 4:57928694..57992653 Genome browser AA seq 917 aa AA seqDB search MIASHLLAYFFTELNHDQVQKVDQYLYHMRLSDETLLEISKRFRREMEKGLGATTHPTAS VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMR GSGTQLFDHIAECLANFMEKLQIKEKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGV EGRDVVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYME EMRHIDMVEGDEGRMCINMEWGAFGDDGALNDIRTEFDREIDMGSLNPGKQLFEKMISGM YMGELVRLILVKMAREELLFGGKLSPELLTTGRFETKDISDIEGEKDGIRKAREVLVRLG LDPTQEDCVATHRICQIVSTRSASLCAATLAAVLRRIKENKSEDRLRSTIGVDGSVYKKH PHFAKRLHKAVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLEPLKLS REQLLEVKRRMKLEMERGLSKETHAIAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV LLVRVRNGKWGGVEMHNKIYSIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGF TFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVG TMMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDD FRTEFDVAVDELSLNPSKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRG IFETKFLSQIESDCLALLQVRAILQHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA VVDKIRENRGLDTLKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDVSFLESEDGSGKG AALITAVACRIRDAGQR NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgatcgcctcgcatctgctcgcctacttcttcacggagctcaaccatgaccaagtgcag aaggttgaccagtatctctaccacatgcgtctctctgatgagactcttctggagatctcc aagcggttccgcagggagatggagaaagggctcggggccaccacccaccccactgcatca gtgaaaatgctgcccacctttgtgaggtctactccagacgggacagaacatggagagttt ctggctctggaccttggagggaccaatttccgtgtgctttgggtgaaagtgacagacaat gggctccagaaggtcgagatggagaaccagatctatgccatccctgaggacatcatgcgg ggcagcggcacccagctatttgaccacattgccgaatgcctggctaacttcatggagaag ctgcagatcaaagagaagaagctcccgttgggtttcaccttctcgttcccctgccaccag acgaaactagacgagagtttcctggtctcctggacaaaggggttcaagtccagtggagtg gaaggcagagacgtcgtggctctgatccgcaaggccattcagcggagaggggactttgat attgacatcgtggccgtggtgaacgacactgttgggaccatgatgacctgtggttatgat gaccacaactgtgaaattggtctcattgtgggcacaggcagcaacgcctgctacatggag gagatgcgccacatcgacatggtggagggtgacgaggggcgcatgtgcatcaacatggag tggggggcctttggggacgacggcgcgctcaacgacatccgcaccgagtttgaccgggag atcgacatgggctcgctgaaccctgggaagcagctgtttgagaagatgatcagtgggatg tacatgggggagctggtgcggctcatcctggtgaagatggccagggaggagctgctcttc ggcgggaagctcagcccggaactcctcaccacgggccgcttcgagaccaaggacatttca gatatcgaaggggagaaagatggcatccggaaggcccgtgaggtcctggtgcggctgggc ctggacccgacgcaggaggactgcgtggccactcaccgcatctgccagatcgtgtccacg cgctcagccagcctgtgcgcggccaccctggccgccgtgctgcggcgcatcaaggagaac aagagcgaggatcggctgcgctccaccatcggggtcgacggctccgtctacaagaagcac ccccattttgccaagcgtcttcacaaggctgtgcggcggctggtgcctgactgcgatgtc cgcttcctccgctccgaggatggcagcggcaagggtgcagccatggtgacagcagtggct taccggttagccgaccagcaccgagcccgccaaaagaccctagagcctctgaagctgagc cgtgagcagctcctggaggtcaagaggaggatgaagctagaaatggagcgaggtctgagc aaagagacgcacgccattgcccctgtcaagatgctgcccacctatgtgtgtgccacccct gatggcacagagaaaggggacttcctggccttggaccttggaggaaccaatttccgggtc ctgctggtgcgcgtgcggaacgggaagtggggtggagtggagatgcacaacaagatctac tccatcccgcaggaggtcatgcatggcactggggacgagctgttcgaccacatcgtccag tgcatcgccgacttccttgagtacatgggcatgaagggtgtgtccctgccgctgggtttc accttctccttcccttgccagcagaacagcctggacgagagtatcctcctcaagtggaca aaaggcttcaaggcatctggctgcgagggcgaggacgtggtcaccctgctgaaggaagcc atccaccggcgagaggagtttgacctggatgtggttgctgtggtgaatgacacggtcggg accatgatgacctgtggctacgaagaccctcactgtgaagtgggcctcatcgttggcacg ggcagcaacgcctgctacatggaggagatgcgcaacgtggagctggtggaaggagaggag gggcggatgtgcgtcaacatggagtggggggccttcggggacaacggctgcctcgacgac ttccgcacggaatttgatgtggccgtggacgaactttccctcaaccccagcaagcagagg ttcgagaagatgatcagtggaatgtatctgggcgagattgtccggaacatcctaatagac ttcaccaaacgtgggctcctcttccgaggtcgcatctcagagcggctcaagacaagggga atctttgaaaccaagttcctgtctcagatcgagagcgactgcctggccctgctgcaggtc cgagccatcctgcagcacctgggccttgagagcacctgcgacgacagtatcatcgtcaag gaggtgtgcaccgtggtggcgcggcgggcagcccagctctgtggcgcaggcatggctgcc gtggtggacaagatacgagaaaaccgtgggctggacactctcaaagtgacagtgggtgtg gatgggaccctctacaagctccatcctcattttgctaaagtcatgcacgagacagtgaag gacctggctccgaaatgtgatgtgtccttcctggagtcagaggatggcagtgggaagggg gcagctctcatcactgccgtggcctgccgcatccgtgatgctggacagcgatag

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