Lemur catta (Ring-tailed lemur): 123638501 Help Entry 123638501         CDS       T08326                                  Symbol TLR2 Name (RefSeq) toll-like receptor 2   KO K10159   toll-like receptor 2 Organism lcat  Lemur catta (Ring-tailed lemur) Pathway lcat04145   Phagocytosis lcat04151   PI3K-Akt signaling pathway lcat04613   Neutrophil extracellular trap formation lcat04620   Toll-like receptor signaling pathway lcat05132   Salmonella infection lcat05134   Legionellosis lcat05140   Leishmaniasis lcat05142   Chagas disease lcat05144   Malaria lcat05145   Toxoplasmosis lcat05146   Amoebiasis lcat05152   Tuberculosis lcat05161   Hepatitis B lcat05162   Measles lcat05168   Herpes simplex virus 1 infection lcat05169   Epstein-Barr virus infection lcat05170   Human immunodeficiency virus 1 infection lcat05171   Coronavirus disease lcat05205   Proteoglycans in cancer lcat05235   PD-L1 expression and PD-1 checkpoint pathway in cancer lcat05321   Inflammatory bowel disease lcat05323   Rheumatoid arthritis lcat05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:lcat00001]  09130 Environmental Information Processing   09132 Signal transduction    04151 PI3K-Akt signaling pathway     123638501 (TLR2)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagocytosis     123638501 (TLR2)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     123638501 (TLR2)    04620 Toll-like receptor signaling pathway     123638501 (TLR2)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     123638501 (TLR2)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     123638501 (TLR2)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     123638501 (TLR2)    05161 Hepatitis B     123638501 (TLR2)    05171 Coronavirus disease     123638501 (TLR2)    05162 Measles     123638501 (TLR2)    05168 Herpes simplex virus 1 infection     123638501 (TLR2)    05169 Epstein-Barr virus infection     123638501 (TLR2)   09171 Infectious disease: bacterial    05132 Salmonella infection     123638501 (TLR2)    05134 Legionellosis     123638501 (TLR2)    05152 Tuberculosis     123638501 (TLR2)   09174 Infectious disease: parasitic    05146 Amoebiasis     123638501 (TLR2)    05144 Malaria     123638501 (TLR2)    05145 Toxoplasmosis     123638501 (TLR2)    05140 Leishmaniasis     123638501 (TLR2)    05142 Chagas disease     123638501 (TLR2)   09163 Immune disease    05323 Rheumatoid arthritis     123638501 (TLR2)    05321 Inflammatory bowel disease     123638501 (TLR2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     123638501 (TLR2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:lcat04131]     123638501 (TLR2)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:lcat04147]     123638501 (TLR2)    04054 Pattern recognition receptors [BR:lcat04054]     123638501 (TLR2)    04090 CD molecules [BR:lcat04090]     123638501 (TLR2)    00536 Glycosaminoglycan binding proteins [BR:lcat00536]     123638501 (TLR2) Membrane trafficking [BR:lcat04131]  Endocytosis   Phagocytosis    Toll-like receptors     123638501 (TLR2) Exosome [BR:lcat04147]  Exosomal proteins   Exosomal proteins of breast milk    123638501 (TLR2) Pattern recognition receptors [BR:lcat04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    123638501 (TLR2) CD molecules [BR:lcat04090]  Proteins   123638501 (TLR2) Glycosaminoglycan binding proteins [BR:lcat00536]  Hyaluronan   Cell surface receptors    123638501 (TLR2) SSDB OrthologParalogGFIT Motif Pfam:  LRR_8 LRR_4 TIR TIR_2 LRR_9 LRR_5 LRR_1 LRR_Zer-1 LRRCT LRR_LRWD1 TANGO2 LRR_NXF1-5 Motif Other DBs NCBI-GeneID:  123638501 NCBI-ProteinID:  XP_045408097 LinkDB All DBs Position 5:76273453..76352294 Genome browser AA seq 784 aa AA seqDB search MPYALWMAWALGAVISLSNKGSFGQASLTCDSTGVCVGHSSSLNSIPSGLTAAVKSLDLS NNKITYIGKSDLQRCVNLQALVLKSNGINTIEEDSFFSLGSLKHLDLSYNDLSNLSSSWF RPLSSLESLNLLGNPYKTLGETSVFSHLTNLRTLRVGNTNSFTKIQRKDFAGLTFLQELE IDASALQSYEPKSLRSIQNVSNLTLRMSEPILLLEIFVDLLSSVECVELRDVDLYNFHFS ELSINETNPLIKKFTLRNVKMTDESLAEVLKLMTYASELLELEFDDCTLDGVGDFSTFDE DIIKDPGKVETLTIRRLRILHFYSFNDLRTVYSLTGRVKRITVENSKVFLVPCLLSQHLK SLEYLDLNENLMLEEQLKNSACEDAWPSLHTLILRQNHLTSLGKTAEILLTLKNLTHLDI SKNNFHSMPKTCQWPEKMKYLNLSSTRIHNLTYCVPQTLEILDVSSNNLNSFSVTLPQLK ELYISKNKLKTLPDASFLPALLVLSIRTNTITTFSKGQLDSFHKLKTLEASGNAFICSCE FVSFTREQQALAKVFINWTENYLCDSPSHVRGQRVQDVRLSVSECHRAALVSGMCCALFL LILLTGVLCHRFHGVWYMKMMWAWLQAKRKPRKAPRRDICYDAFVSYSEQDSYWVENLMV QELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTVFVLSENFVKSEWCKYELDFS HFRLFDENNDAAILILLEPIEKKAIPQRFCKLRKIMNTKTYLEWPSDGALQEGFWFNLRA ALKS NT seq 2355 nt NT seq  +upstreamnt  +downstreamnt atgccatatgctttgtggatggcgtgggccttgggggctgtcattagcctctccaacaaa gggtcctttggtcaggcttctctgacttgtgactccactggtgtctgtgttggccactcg agctctttaaactccattccctcagggcttacagcagctgtgaaaagtcttgacctgtcc aacaacaagatcacctatattggcaaaagtgacctgcagaggtgtgtgaacctccaggct ctggtgctaaagtccaatggaattaacacaatagaggaagattcttttttttccctgggc agtctgaaacatttggacttatcctataatgacttatctaatttatcatcctcctggttc aggcccctttcttccttggagtccttaaacttactgggaaatccttacaaaacactcggg gaaacatctgtcttttctcatctcacaaatttgcgaaccctaagagtgggaaatactaac agcttcactaagattcagagaaaggattttgctggactcacctttcttcaggaacttgag attgatgcttcagctctacagagttatgagccaaaaagtttgaggtcgattcagaacgta agtaatctgacccttcgtatgagtgagcctatcttactactggagatttttgtagatctt ttaagttccgtggaatgtgtggaactgagagatgttgatttgtataatttccatttttca gaactctccatcaatgaaacaaatccattgattaaaaagtttacattgagaaatgtgaaa atgaccgatgaaagtttggctgaggttctaaaacttatgacttatgcttctgaattgtta gagttagagtttgatgactgtacccttgatggagtaggtgattttagtacatttgatgaa gacataattaaagatccaggtaaagtagaaacattaactatacggaggttgcgtatttta catttttattcatttaatgatctgaggacagtatattcacttacaggaagagttaaaaga atcacagtagaaaacagtaaggtttttctggttccttgtttactttcacaacatttaaaa tcattagaatacttggatctcaatgaaaatttgatgttagaggaacagttgaaaaattca gcctgtgaggatgcctggccctctctacataccttaattttaaggcaaaatcatttaaca tcattaggaaaaactgcagagattttgcttactctgaaaaacctgactcaccttgatatc agtaagaataattttcattctatgcctaaaacttgtcagtggccagaaaagatgaaatat ttgaacttatccagcacacgaatacacaatttaacctactgcgttccccagacactggaa attttagatgtcagcagtaacaacctcaattcattttctgtgactttgccacaactcaaa gaactttatatttccaaaaataagttgaagactctaccagatgcctccttcttacccgca ttactggtgttgagcatcagaacgaacacaataactactttttctaaggggcaacttgat tcttttcacaaactgaaaactttggaagccagtggcaatgccttcatttgctcctgtgag ttcgtctctttcacccgggagcagcaagcattggccaaggtcttcatcaattggacggaa aactacctgtgtgattctccatcccacgtgcggggccagcgggttcaggatgtccgtctc tcggtgtctgagtgtcacagggcagcactggtgtctggcatgtgctgtgccctcttcctg ttgatcctgctcactggggtgctgtgccaccgtttccacggagtgtggtacatgaaaatg atgtgggcctggctccaggccaaaaggaagccccggaaggctcccaggagggacatctgt tacgatgcctttgtttcttacagtgaacaggattcctactgggtggagaacctgatggtc caggagctggagaatttcaacccccccttcaagttgtgtcttcataagcgggactttatt cctggcaagtggatcatcgacaatatcattgactccatcgaaaagagccacaaaactgtc tttgtgctctctgaaaactttgtgaagagtgagtggtgcaagtacgaactggatttctcc cattttcggctctttgatgagaacaatgatgctgccattctcattcttctggagcccatc gagaagaaagccattccccagcgcttctgtaagctgcggaagataatgaacaccaagacc tacctggagtggcccagtgacggggctctgcaggaggggttctggttcaacttgagggct gcactaaagtcctag

Lemur catta (Ring-tailed lemur): 123646094 Help Entry 123646094         CDS       T08326                                  Symbol TLR4 Name (RefSeq) toll-like receptor 4   KO K10160   toll-like receptor 4 Organism lcat  Lemur catta (Ring-tailed lemur) Pathway lcat04064   NF-kappa B signaling pathway lcat04066   HIF-1 signaling pathway lcat04145   Phagocytosis lcat04151   PI3K-Akt signaling pathway lcat04217   Necroptosis lcat04613   Neutrophil extracellular trap formation lcat04620   Toll-like receptor signaling pathway lcat04621   NOD-like receptor signaling pathway lcat04936   Alcoholic liver disease lcat05132   Salmonella infection lcat05133   Pertussis lcat05134   Legionellosis lcat05135   Yersinia infection lcat05140   Leishmaniasis lcat05142   Chagas disease lcat05144   Malaria lcat05145   Toxoplasmosis lcat05146   Amoebiasis lcat05152   Tuberculosis lcat05161   Hepatitis B lcat05162   Measles lcat05164   Influenza A lcat05170   Human immunodeficiency virus 1 infection lcat05171   Coronavirus disease lcat05205   Proteoglycans in cancer lcat05235   PD-L1 expression and PD-1 checkpoint pathway in cancer lcat05321   Inflammatory bowel disease lcat05323   Rheumatoid arthritis lcat05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:lcat00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     123646094 (TLR4)    04066 HIF-1 signaling pathway     123646094 (TLR4)    04151 PI3K-Akt signaling pathway     123646094 (TLR4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagocytosis     123646094 (TLR4)   09143 Cell growth and death    04217 Necroptosis     123646094 (TLR4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     123646094 (TLR4)    04620 Toll-like receptor signaling pathway     123646094 (TLR4)    04621 NOD-like receptor signaling pathway     123646094 (TLR4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     123646094 (TLR4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     123646094 (TLR4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     123646094 (TLR4)    05161 Hepatitis B     123646094 (TLR4)    05171 Coronavirus disease     123646094 (TLR4)    05164 Influenza A     123646094 (TLR4)    05162 Measles     123646094 (TLR4)   09171 Infectious disease: bacterial    05132 Salmonella infection     123646094 (TLR4)    05135 Yersinia infection     123646094 (TLR4)    05133 Pertussis     123646094 (TLR4)    05134 Legionellosis     123646094 (TLR4)    05152 Tuberculosis     123646094 (TLR4)   09174 Infectious disease: parasitic    05146 Amoebiasis     123646094 (TLR4)    05144 Malaria     123646094 (TLR4)    05145 Toxoplasmosis     123646094 (TLR4)    05140 Leishmaniasis     123646094 (TLR4)    05142 Chagas disease     123646094 (TLR4)   09163 Immune disease    05323 Rheumatoid arthritis     123646094 (TLR4)    05321 Inflammatory bowel disease     123646094 (TLR4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     123646094 (TLR4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     123646094 (TLR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:lcat04131]     123646094 (TLR4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:lcat04054]     123646094 (TLR4)    04090 CD molecules [BR:lcat04090]     123646094 (TLR4)    00536 Glycosaminoglycan binding proteins [BR:lcat00536]     123646094 (TLR4) Membrane trafficking [BR:lcat04131]  Endocytosis   Phagocytosis    Toll-like receptors     123646094 (TLR4) Pattern recognition receptors [BR:lcat04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    123646094 (TLR4) CD molecules [BR:lcat04090]  Proteins   123646094 (TLR4) Glycosaminoglycan binding proteins [BR:lcat00536]  Hyaluronan   Cell surface receptors    123646094 (TLR4) SSDB OrthologParalogGFIT Motif Pfam:  LRR_8 TIR LRR_4 TIR_2 LRR_9 LRR_Zer-1 LRR_NXF1-5 LRR_6 ThsB_TIR LRR_R13L1-DRL21 Sec3_C_2 Motif Other DBs NCBI-GeneID:  123646094 NCBI-ProteinID:  XP_045418706 LinkDB All DBs Position 10:complement(17650480..17665075) Genome browser AA seq 830 aa AA seqDB search MMFPSHLAGALIPAMAFLSCLRPESCEPCVEVVPNITYECMDLNLYKIPDNIPSSTKNLD LSFNHLRHLGSHSFSNFPELQVLDLSRCEIQTIEDDAYQSLNHLSTLILTGNPIQSLAPG AFSGLSSLQKLVAVEINLISLENLPIGHLKGLKELNVAHNFIHSFKLPEYFSNLPKLEHL DLSKNNIQNIYHEDLHVLHQNSSLNLSLDLSLNPIDFIQPGSFKGIRLHKLTLRSNFDSV NIMKTCIQGLAGLEVHRLVWGEFRNERYVKDFDKSALEGLCNLAIEEFSLANLEESLKDA DLFHCLTNVSAISLVSLDLNYLKGFYNNYGWRSLELVNCKFEQFPTLELFSLERFILTHN KDGLTFAEVELPSLEYLDISKNGLSFKGCCSHTDFETNRLTYLDLSFNGIITMSSNFLGL EGLQHLDFRHSTLKQTSDFPVFLSLKNLRYLDISYTHTRVVFHGIFDGLVSLEVLKMAGN SFQDNVLPDVFQKMTNLTFLDLSECRLEQVTQKAFNSLSSLRLLNISHNNLLSLDILPYK SLQSLHVLDCSFNRIVASKNQELQYFPSSLAFLNLTQNDFACVCEHQSFLQWVKDQRQLL VEAEQMVCATPLDMQGIPVLSFRNTTCQMSKTIISVSVVIFLMVSVVVVLVYKFYFHLML LAGCKKYSRGESTYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAA NIIQEGFHKSRKVIVVVSNHFLQSRWCIFEYEIAQTWQFLSSHAGIIFIVLQKVEKSLLR QQVELYCLLKRNTYLEWEDSVLGRHIFWRRLRKALLDGKPWSPEGTEGAE NT seq 2493 nt NT seq  +upstreamnt  +downstreamnt atgatgtttccctcgcatctggctggggctctgatcccggccatggccttcctctcctgc ctgcgaccggaaagctgtgagccctgcgtggaggtggttcctaacattacttacgagtgc atggatctgaatctctacaaaatccccgacaacatcccctcctcaaccaagaacctggac ctgagttttaaccacctgaggcacttaggcagccatagcttctccaatttcccagaactg caggtgctggatttatccaggtgtgaaatccagacgattgaagatgatgcgtatcagagc ctaaaccatctttccaccttgatattgacaggaaaccctatccagagtttagccccagga gccttttctggactatcaagtttacagaagctggtggccgtggagataaacctaatctct ctagagaacttacccattggacacctcaaaggcttgaaggagcttaatgtggctcacaat tttatccattctttcaagttacctgaatatttttctaacctacccaagctggagcacttg gacctttccaaaaataacattcaaaatatttatcatgaagacttgcatgttctacatcaa aattcttcactcaatctctctttagacctgtccttgaaccctatagactttattcagcct ggttcctttaaaggaattaggctccataaactgactttgagaagtaattttgatagtgtg aatataatgaaaacttgtattcagggtctggctggtttagaagtccatcgattggtttgg ggagaatttagaaatgaaaggtacgtgaaagattttgacaaatctgccctggagggactg tgcaatttggccattgaagaattcagtttagcaaacttagaagaaagtctgaaagatgct gatttatttcattgtttgacaaatgtttctgcaatttccctggtgagtttggatttaaac tatctaaaaggcttttataataattatggatggcgatctttagaattagttaactgtaaa tttgaacaatttcccacactggagctcttttctcttgaaaggtttattttaactcacaac aaagatgggctcacttttgcagaagttgagctacccagccttgaatatctagatatcagt aaaaatggcttgagtttcaagggttgctgttctcatactgattttgagacaaacagactg acatatttagatctgagcttcaatggtattattaccatgagttcaaatttcctgggctta gaaggactacaacatctggatttccggcattccactttgaaacagactagtgatttccca gtattcctatcactcaaaaacctacgttaccttgacatttcttatactcacacccgagtt gtcttccatggcatctttgatggcttggtcagtctcgaagtcttgaaaatggctggcaat tctttccaagacaacgtccttccagatgtcttccaaaaaatgactaacttgactttcctg gacctctctgaatgtcgactggaacaggtaacccagaaagcatttaactcactctccagt cttcgattactaaatataagccacaacaacctcttatcattggatatacttccttataag tctctccagtccctccatgttctagattgcagcttcaatcgcatagtggcttccaaaaac caagaactacagtattttccaagtagtctagctttcttaaatcttactcagaatgacttt gcttgtgtttgtgaacaccagagtttcctgcagtgggtcaaggaccagaggcagctcttg gtggaagctgaacaaatggtatgcgcaacacctttagacatgcagggcatacctgtactg agttttaggaacaccacctgtcagatgagcaagaccataatcagcgtgtcagtggtcatt ttcctcatggtatctgttgtagtagttctggtctataagttttattttcacctgatgctt cttgctggatgcaaaaaatacagtagaggtgaaagcacctatgatgcctttgtcatctac tcaagccaggatgaggactgggtgaggaatgagctagtgaagaatttagaagaaggagtg cccccctttcagctctgccttcactacagagactttattcccggtgtggccatcgctgcc aacatcatccaggaaggtttccacaaaagccggaaggttattgttgtggtgtccaatcac ttcctccaaagccgctggtgtatctttgagtatgagattgctcagacctggcagtttctg agcagtcatgctggtatcatcttcattgtcctgcagaaggtggagaagtccctgctccgg cagcaggtggagctgtactgccttctcaagaggaacacttacctggagtgggaggacagt gtgctggggcggcacatcttctggagacgactcagaaaagccctgttggatggtaaacca tggagtccagaagggacagagggtgcagaatga

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