Lemur catta (Ring-tailed lemur): 123639564
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Entry
123639564 CDS
T08326
Symbol
JAK3
Name
(RefSeq) tyrosine-protein kinase JAK3 isoform X1
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
lcat
Lemur catta (Ring-tailed lemur)
Pathway
lcat04062
Chemokine signaling pathway
lcat04151
PI3K-Akt signaling pathway
lcat04217
Necroptosis
lcat04550
Signaling pathways regulating pluripotency of stem cells
lcat04630
JAK-STAT signaling pathway
lcat04658
Th1 and Th2 cell differentiation
lcat04659
Th17 cell differentiation
lcat05161
Hepatitis B
lcat05162
Measles
lcat05166
Human T-cell leukemia virus 1 infection
lcat05169
Epstein-Barr virus infection
lcat05200
Pathways in cancer
lcat05203
Viral carcinogenesis
lcat05223
Non-small cell lung cancer
lcat05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
lcat00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
123639564 (JAK3)
04151 PI3K-Akt signaling pathway
123639564 (JAK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
123639564 (JAK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
123639564 (JAK3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
123639564 (JAK3)
04659 Th17 cell differentiation
123639564 (JAK3)
04062 Chemokine signaling pathway
123639564 (JAK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123639564 (JAK3)
05203 Viral carcinogenesis
123639564 (JAK3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
123639564 (JAK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
123639564 (JAK3)
05161 Hepatitis B
123639564 (JAK3)
05162 Measles
123639564 (JAK3)
05169 Epstein-Barr virus infection
123639564 (JAK3)
09163 Immune disease
05340 Primary immunodeficiency
123639564 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lcat01001
]
123639564 (JAK3)
Enzymes [BR:
lcat01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
123639564 (JAK3)
Protein kinases [BR:
lcat01001
]
Non-receptor tyrosine kinases
JAK family [OT]
123639564 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2_1
FERM_F2
FERM_F1
Jak1_Phl
Kinase-like
ABC1
SH2
Kdo
LRR_RI_capping
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
123639564
NCBI-ProteinID:
XP_045409405
LinkDB
All DBs
Position
1:complement(120406199..120420845)
Genome browser
AA seq
1113 aa
AA seq
DB search
MAPPSEETPLIPQRSCSLSSSEAGALHVLLPTRGPGPPLRLSFSFGDHLAEELCVQAAKA
SGILPVYHSLFALATEDLSCWFPPSHIFSVEDAGTQVLLYRLRFYFPNWFGLEKCHRFGL
RKDLTSAILDLPVLEHLFAQLMLPVTGPQHRSDLLSGHLPVGLSLKEQGECLSLAVLDLA
RMAREQAQRPAELLKTVSYKACLPPSLRDMIQGLSFVTRRRIRRTVRRALRRVAACQADR
HSLMAKYILDLERLDPAGAAETFRVGLPGASGGQDGLRLLRVAGGSGLAWSPGEDQAFQP
FCDFPEIVDISIKQAPCVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFRL
TTDSRHFFCKEVAPPRLLEEVAEQCHGPITLDFAVHKLKAAGSRPGSYVLRRSPQDFDSF
LLTVCVQTPLGPDYKGCLIRRDPPGTFSLVDLGRPHSSLRELLAACWEGGLHVDGVALTL
TSCCTPRPKEKSNLIVVRSGCSLPTSSPVHPQSQRQLSQMTFHKIPANSLQWHENLGHGS
FTKIYRGCRHEAVDGEARDTEVLLKVMDAKHKNCMESFLEAASLMSQVSYQHLVLLHGVC
MAGDSTMVQEFVHLGAIDMYLRKRGHLVPASWKLQVTKQLAYALNYLEDKGLPHGNVSAR
KVLLAREGADGSPPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEAQTLGLEADKWGF
GATVWEVFSGVTMPISTLDPAKKLQFYEQRKQLPAPKWTELALLIQQCMAYDPGQRPSFR
AVIRDLNNLITSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKG
NFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKAMHSDFIVKYRGVSY
GPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYASQICKGMEYLGSRRCVHRDLA
ARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVW
SFGVVLYELFTYSDKSCSPSSEFLRMMGCERDAPALCRLLELLEEGQRLPAPPACPAEVH
ELMKLCWAPRPQDRPSFSTLGPQLEALWGGRRG
NT seq
3342 nt
NT seq
+upstream
nt +downstream
nt
atggcgcctcccagtgaggagacacccttgattcctcagcgctcctgtagcctctcgtcc
tcagaggctggtgccctgcacgtgctgctgcccactcggggccctgggccacccctgcgc
ctatctttctcctttggggaccacttggctgaggagctgtgtgtgcaggctgccaaggcc
agcggcatcctgcctgtgtaccactcactctttgccctggccacggaggacctgtcctgc
tggttccccccgagccacatcttctctgtggaggacgcgggcacccaagtcttgctctac
aggctccgcttttacttccccaactggtttgggctggagaagtgccaccgcttcgggtta
cgcaaggatctgaccagtgccatccttgacctgccagtcctggagcacctctttgcccag
ctgatgcttcctgtgactggcccccagcaccgcagtgacctgctgagcgggcacctccct
gtaggcctcagcctcaaggagcagggtgagtgtctcagcctggccgtgctggacctggcc
cggatggcccgtgagcaggcccagcggccagcggagctgctaaagaccgtcagctacaag
gcctgcctgccccccagcctgcgcgacatgatccagggcctgagcttcgtcacgcggagg
cgcattcgcaggactgtgcgtcgggccctgcgccgcgtggccgcctgccaggcagaccgg
cactcgctcatggccaagtacatcctggacctggagaggctggatccagcgggggccgcc
gaaaccttccgcgtggggctcccaggggcctccgggggccaggatgggctgaggctgctc
cgcgtggctggtggcagcggcctggcctggagcccgggagaagaccaggccttccagcct
ttctgcgactttccagagatcgtagacattagcatcaagcaggctccttgtgttggtccg
gccggggagcaccgcctggtcaccgtcaccaggacagacaaccagatcctggaggctgag
ttcccggggctgcctgaggcgctgtccttcgtggcgctcgtggacggctacttccggctg
accacggactcccggcacttcttctgcaaggaggtggcaccaccgcggctgctggaagag
gtggccgagcagtgccacggccccatcactctggatttcgctgtccacaagctcaaggct
gcaggctcacggccaggctcctatgttctccgccgcagcccgcaggacttcgacagcttc
ctcctaaccgtctgtgtccagacccccctgggccctgactacaagggctgcctcattcgg
cgagaccccccaggaaccttctccctggttgaccttggccggccccacagcagtcttcga
gagctcctggcagcctgctgggaaggtgggctgcacgtcgatggggtggcactgaccctc
acctcctgctgcacccccagacccaaagaaaagtccaacctgattgtggtccggagtggt
tgcagcctgcccacgtcatcccctgttcatccccaatcccaacgccagctgagtcagatg
acatttcacaagatccctgccaacagcctgcagtggcatgagaacctgggccatgggtcc
ttcaccaagatttaccggggttgtcgccacgaggctgtggatggtgaggcccgagacaca
gaggtgctgttgaaggtgatggatgccaagcacaagaactgcatggagtcattcctggaa
gccgcaagcttgatgagccaagtgtcctaccagcatctcgtgctgctccatggcgtgtgc
atggctggagacagcaccatggtgcaggaattcgtacaccttggagcaatagacatgtat
ctgcgcaagcgtggccacctggtgccagccagctggaagctgcaggtgaccaaacagctg
gcctatgccctcaactatctggaggacaaaggccttccccatggcaatgtctcagctcgg
aaggtgctcctggctcgggagggggctgatgggagcccacccttcatcaagctgagtgac
cctggggtcagccccacagtgctaagcctggagatgctcaccgacaggatcccctgggtg
gcccctgagtgtctccaggaggcccagacacttggcttggaagctgacaagtggggcttc
ggtgccacagtctgggaggtgttcagtggggtcaccatgcccatcagcaccctggatcct
gccaagaaactccagttttacgagcaacggaagcagctgccagcccccaagtggacagag
ctggccttgctgatccaacagtgcatggcctacgatccaggccagaggccctccttccga
gccgtcatccgtgacctcaacaaccttatcacttcagattatgagctcctctcagacccc
acacctggtgccctggcgccccgtgatgggctgtggaatggtgcccagctctatgcctgc
caggaccccaccatctttgaggagagacatctgaagtacatctcacagctgggcaagggc
aactttggcagcgtggagctgtgccgctacgacccgctgggggacaacacaggcgccctg
gtggctgtgaagcagctgcagcacagtgggccagaccagcagagggacttccagcgagag
atccagatcctcaaagccatgcacagtgacttcatcgtcaagtaccgcggtgtcagctat
ggccccggccgccagagcttgcgtctggtcatggagtacctgcccagcggctgcctgcgc
gacttcctgcagcggcaccgcgcgcgcctggacgccagccggctcctcctctacgcctcg
cagatctgcaagggcatggagtacctgggctcccgccgctgcgtgcaccgcgacctggct
gcccggaacatcctagtggagagcgaggcgcacgtcaagatcgctgacttcggcctggcc
aagctgctgccgctcgacaaagactactacgtggtccgcgagcccggccagagcccgatc
ttctggtacgcccccgagtccctctcggacaacatcttctcgcgccagtcagacgtctgg
agcttcggggtcgtcctgtacgagctcttcacctacagcgacaaaagctgcagcccctcg
tccgagttcctgcggatgatgggatgtgagcgagatgcccctgccctctgtcgcctcctg
gaactgttggaggagggtcagaggctgccggcgcctcctgcctgccctgctgaggttcac
gagctcatgaagctgtgctgggcccctagaccccaggaccggccgtcattcagcaccttg
ggcccccagctggaggcgttgtggggtggaagacgggggtag
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