Lemur catta (Ring-tailed lemur): 123639706
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Entry
123639706 CDS
T08326
Symbol
PIK3R2
Name
(RefSeq) phosphatidylinositol 3-kinase regulatory subunit beta
KO
K02649
phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
lcat
Lemur catta (Ring-tailed lemur)
Pathway
lcat01521
EGFR tyrosine kinase inhibitor resistance
lcat01522
Endocrine resistance
lcat01524
Platinum drug resistance
lcat04012
ErbB signaling pathway
lcat04014
Ras signaling pathway
lcat04015
Rap1 signaling pathway
lcat04024
cAMP signaling pathway
lcat04062
Chemokine signaling pathway
lcat04066
HIF-1 signaling pathway
lcat04068
FoxO signaling pathway
lcat04070
Phosphatidylinositol signaling system
lcat04071
Sphingolipid signaling pathway
lcat04072
Phospholipase D signaling pathway
lcat04081
Hormone signaling
lcat04140
Autophagy - animal
lcat04145
Phagocytosis
lcat04150
mTOR signaling pathway
lcat04151
PI3K-Akt signaling pathway
lcat04152
AMPK signaling pathway
lcat04210
Apoptosis
lcat04211
Longevity regulating pathway
lcat04213
Longevity regulating pathway - multiple species
lcat04218
Cellular senescence
lcat04360
Axon guidance
lcat04370
VEGF signaling pathway
lcat04380
Osteoclast differentiation
lcat04510
Focal adhesion
lcat04517
IgSF CAM signaling
lcat04518
Integrin signaling
lcat04550
Signaling pathways regulating pluripotency of stem cells
lcat04611
Platelet activation
lcat04613
Neutrophil extracellular trap formation
lcat04620
Toll-like receptor signaling pathway
lcat04625
C-type lectin receptor signaling pathway
lcat04630
JAK-STAT signaling pathway
lcat04650
Natural killer cell mediated cytotoxicity
lcat04660
T cell receptor signaling pathway
lcat04662
B cell receptor signaling pathway
lcat04664
Fc epsilon RI signaling pathway
lcat04666
Fc gamma R-mediated phagosome formation
lcat04668
TNF signaling pathway
lcat04670
Leukocyte transendothelial migration
lcat04722
Neurotrophin signaling pathway
lcat04725
Cholinergic synapse
lcat04750
Inflammatory mediator regulation of TRP channels
lcat04810
Regulation of actin cytoskeleton
lcat04910
Insulin signaling pathway
lcat04914
Progesterone-mediated oocyte maturation
lcat04915
Estrogen signaling pathway
lcat04917
Prolactin signaling pathway
lcat04919
Thyroid hormone signaling pathway
lcat04923
Regulation of lipolysis in adipocytes
lcat04926
Relaxin signaling pathway
lcat04929
GnRH secretion
lcat04930
Type II diabetes mellitus
lcat04931
Insulin resistance
lcat04932
Non-alcoholic fatty liver disease
lcat04933
AGE-RAGE signaling pathway in diabetic complications
lcat04935
Growth hormone synthesis, secretion and action
lcat04960
Aldosterone-regulated sodium reabsorption
lcat04973
Carbohydrate digestion and absorption
lcat05010
Alzheimer disease
lcat05017
Spinocerebellar ataxia
lcat05020
Prion disease
lcat05100
Bacterial invasion of epithelial cells
lcat05135
Yersinia infection
lcat05142
Chagas disease
lcat05146
Amoebiasis
lcat05160
Hepatitis C
lcat05161
Hepatitis B
lcat05162
Measles
lcat05163
Human cytomegalovirus infection
lcat05164
Influenza A
lcat05165
Human papillomavirus infection
lcat05166
Human T-cell leukemia virus 1 infection
lcat05167
Kaposi sarcoma-associated herpesvirus infection
lcat05168
Herpes simplex virus 1 infection
lcat05169
Epstein-Barr virus infection
lcat05170
Human immunodeficiency virus 1 infection
lcat05171
Coronavirus disease
lcat05200
Pathways in cancer
lcat05203
Viral carcinogenesis
lcat05205
Proteoglycans in cancer
lcat05206
MicroRNAs in cancer
lcat05207
Chemical carcinogenesis - receptor activation
lcat05208
Chemical carcinogenesis - reactive oxygen species
lcat05210
Colorectal cancer
lcat05211
Renal cell carcinoma
lcat05212
Pancreatic cancer
lcat05213
Endometrial cancer
lcat05214
Glioma
lcat05215
Prostate cancer
lcat05218
Melanoma
lcat05220
Chronic myeloid leukemia
lcat05221
Acute myeloid leukemia
lcat05222
Small cell lung cancer
lcat05223
Non-small cell lung cancer
lcat05224
Breast cancer
lcat05225
Hepatocellular carcinoma
lcat05226
Gastric cancer
lcat05230
Central carbon metabolism in cancer
lcat05231
Choline metabolism in cancer
lcat05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
lcat05415
Diabetic cardiomyopathy
lcat05417
Lipid and atherosclerosis
lcat05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
lcat00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
123639706 (PIK3R2)
04014 Ras signaling pathway
123639706 (PIK3R2)
04015 Rap1 signaling pathway
123639706 (PIK3R2)
04370 VEGF signaling pathway
123639706 (PIK3R2)
04630 JAK-STAT signaling pathway
123639706 (PIK3R2)
04668 TNF signaling pathway
123639706 (PIK3R2)
04066 HIF-1 signaling pathway
123639706 (PIK3R2)
04068 FoxO signaling pathway
123639706 (PIK3R2)
04070 Phosphatidylinositol signaling system
123639706 (PIK3R2)
04072 Phospholipase D signaling pathway
123639706 (PIK3R2)
04071 Sphingolipid signaling pathway
123639706 (PIK3R2)
04024 cAMP signaling pathway
123639706 (PIK3R2)
04151 PI3K-Akt signaling pathway
123639706 (PIK3R2)
04152 AMPK signaling pathway
123639706 (PIK3R2)
04150 mTOR signaling pathway
123639706 (PIK3R2)
09133 Signaling molecules and interaction
04081 Hormone signaling
123639706 (PIK3R2)
04517 IgSF CAM signaling
123639706 (PIK3R2)
04518 Integrin signaling
123639706 (PIK3R2)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagocytosis
123639706 (PIK3R2)
04140 Autophagy - animal
123639706 (PIK3R2)
09143 Cell growth and death
04210 Apoptosis
123639706 (PIK3R2)
04218 Cellular senescence
123639706 (PIK3R2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
123639706 (PIK3R2)
04550 Signaling pathways regulating pluripotency of stem cells
123639706 (PIK3R2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
123639706 (PIK3R2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
123639706 (PIK3R2)
04613 Neutrophil extracellular trap formation
123639706 (PIK3R2)
04620 Toll-like receptor signaling pathway
123639706 (PIK3R2)
04625 C-type lectin receptor signaling pathway
123639706 (PIK3R2)
04650 Natural killer cell mediated cytotoxicity
123639706 (PIK3R2)
04660 T cell receptor signaling pathway
123639706 (PIK3R2)
04662 B cell receptor signaling pathway
123639706 (PIK3R2)
04664 Fc epsilon RI signaling pathway
123639706 (PIK3R2)
04666 Fc gamma R-mediated phagosome formation
123639706 (PIK3R2)
04670 Leukocyte transendothelial migration
123639706 (PIK3R2)
04062 Chemokine signaling pathway
123639706 (PIK3R2)
09152 Endocrine system
04910 Insulin signaling pathway
123639706 (PIK3R2)
04923 Regulation of lipolysis in adipocytes
123639706 (PIK3R2)
04929 GnRH secretion
123639706 (PIK3R2)
04915 Estrogen signaling pathway
123639706 (PIK3R2)
04914 Progesterone-mediated oocyte maturation
123639706 (PIK3R2)
04917 Prolactin signaling pathway
123639706 (PIK3R2)
04926 Relaxin signaling pathway
123639706 (PIK3R2)
04935 Growth hormone synthesis, secretion and action
123639706 (PIK3R2)
04919 Thyroid hormone signaling pathway
123639706 (PIK3R2)
09154 Digestive system
04973 Carbohydrate digestion and absorption
123639706 (PIK3R2)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
123639706 (PIK3R2)
09156 Nervous system
04725 Cholinergic synapse
123639706 (PIK3R2)
04722 Neurotrophin signaling pathway
123639706 (PIK3R2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
123639706 (PIK3R2)
09158 Development and regeneration
04360 Axon guidance
123639706 (PIK3R2)
04380 Osteoclast differentiation
123639706 (PIK3R2)
09149 Aging
04211 Longevity regulating pathway
123639706 (PIK3R2)
04213 Longevity regulating pathway - multiple species
123639706 (PIK3R2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123639706 (PIK3R2)
05206 MicroRNAs in cancer
123639706 (PIK3R2)
05205 Proteoglycans in cancer
123639706 (PIK3R2)
05207 Chemical carcinogenesis - receptor activation
123639706 (PIK3R2)
05208 Chemical carcinogenesis - reactive oxygen species
123639706 (PIK3R2)
05203 Viral carcinogenesis
123639706 (PIK3R2)
05230 Central carbon metabolism in cancer
123639706 (PIK3R2)
05231 Choline metabolism in cancer
123639706 (PIK3R2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
123639706 (PIK3R2)
09162 Cancer: specific types
05210 Colorectal cancer
123639706 (PIK3R2)
05212 Pancreatic cancer
123639706 (PIK3R2)
05225 Hepatocellular carcinoma
123639706 (PIK3R2)
05226 Gastric cancer
123639706 (PIK3R2)
05214 Glioma
123639706 (PIK3R2)
05221 Acute myeloid leukemia
123639706 (PIK3R2)
05220 Chronic myeloid leukemia
123639706 (PIK3R2)
05218 Melanoma
123639706 (PIK3R2)
05211 Renal cell carcinoma
123639706 (PIK3R2)
05215 Prostate cancer
123639706 (PIK3R2)
05213 Endometrial cancer
123639706 (PIK3R2)
05224 Breast cancer
123639706 (PIK3R2)
05222 Small cell lung cancer
123639706 (PIK3R2)
05223 Non-small cell lung cancer
123639706 (PIK3R2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
123639706 (PIK3R2)
05170 Human immunodeficiency virus 1 infection
123639706 (PIK3R2)
05161 Hepatitis B
123639706 (PIK3R2)
05160 Hepatitis C
123639706 (PIK3R2)
05171 Coronavirus disease
123639706 (PIK3R2)
05164 Influenza A
123639706 (PIK3R2)
05162 Measles
123639706 (PIK3R2)
05168 Herpes simplex virus 1 infection
123639706 (PIK3R2)
05163 Human cytomegalovirus infection
123639706 (PIK3R2)
05167 Kaposi sarcoma-associated herpesvirus infection
123639706 (PIK3R2)
05169 Epstein-Barr virus infection
123639706 (PIK3R2)
05165 Human papillomavirus infection
123639706 (PIK3R2)
09171 Infectious disease: bacterial
05135 Yersinia infection
123639706 (PIK3R2)
05100 Bacterial invasion of epithelial cells
123639706 (PIK3R2)
09174 Infectious disease: parasitic
05146 Amoebiasis
123639706 (PIK3R2)
05142 Chagas disease
123639706 (PIK3R2)
09164 Neurodegenerative disease
05010 Alzheimer disease
123639706 (PIK3R2)
05017 Spinocerebellar ataxia
123639706 (PIK3R2)
05020 Prion disease
123639706 (PIK3R2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
123639706 (PIK3R2)
05418 Fluid shear stress and atherosclerosis
123639706 (PIK3R2)
05415 Diabetic cardiomyopathy
123639706 (PIK3R2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
123639706 (PIK3R2)
04932 Non-alcoholic fatty liver disease
123639706 (PIK3R2)
04931 Insulin resistance
123639706 (PIK3R2)
04933 AGE-RAGE signaling pathway in diabetic complications
123639706 (PIK3R2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123639706 (PIK3R2)
01524 Platinum drug resistance
123639706 (PIK3R2)
01522 Endocrine resistance
123639706 (PIK3R2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
lcat04131
]
123639706 (PIK3R2)
Membrane trafficking [BR:
lcat04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
123639706 (PIK3R2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI3K_P85_iSH2
SH2
RhoGAP
SH3_1
SH2_1
SH3_9
Ribosomal_L22e
ATG11
Motif
Other DBs
NCBI-GeneID:
123639706
NCBI-ProteinID:
XP_045409725
LinkDB
All DBs
Position
1:120617299..120629127
Genome browser
AA seq
726 aa
AA seq
DB search
MAGAEGFQYRALYPFRRERPEDLELLPGDVLVVSRAALQALGVAEGGERCPQTVGWMPGL
NERTRQRGDFPGTYVEFLGPVALAWPGPRPRGPRPLPARPRDGPPEPGLALPDLPEQFSP
PDVAPPLLVKLVEATERTGLDSESYYRLELPAPRTDWSLSDMDQWDATALADGIKGFLLA
LPAPLVTPEASAEARRALREAAGPLGPLLEPPTLPLHRALTLRFLLQHLGRVARRAPALG
PAVRALGATFGPLLLRAPPASPPPGGASDGSEPNPDFPALLVEKLLREHLEEQEVAPPAL
PPKPSKTKLAPAGLANGGSPPALQDAEWYWGDISREEVNEKLRDTPDGTFLVRDASSKIQ
GEYTLTLRKGGNNKLIKVFHRDGHYGFSEPLTFCSVVDLINHYRHESLAQYNAKLDTRLL
YPVSKYQQDQIVKEDSVEAVGAQLKVYHQQYQDKSREYDQLYEEYTRTSQELQMKRTAIE
AFNETIKIFEEQGETQEKCSKEYLERFRREGNEKEMQRILLNSERLKSRIAEIHESRTKL
EQQLRAQASDNREIDKRMNSLKPDLMQLRKIRDQYLVWLTQKGARQKKINEWLGIKNETE
DQYALMEDEDDLPHHEERTWYVGKINRTQAEEMLSGKRDGTFLIRESSQRGCYACSVVVD
GDTKHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQHNDALAVTLAHPVRAPGPG
PPPAAR
NT seq
2181 nt
NT seq
+upstream
nt +downstream
nt
atggcgggcgctgagggcttccagtaccgggcactgtacccgttccgccgggagcggccg
gaggacctggagctgctgccgggcgacgtgctggtggtgagccgggcagccctgcaggcg
ctaggcgtggcagagggtggcgagcgctgcccgcagaccgtgggctggatgcccggcctc
aacgagcgcacacggcagcgaggtgacttccctggtacctacgtggagttcctagggcct
gtggccctggcctggcctggccctcgcccacggggcccccgtccactgcctgccaggcca
cgcgatgggccccctgagccaggccttgcactccccgacctgccggagcagttctcccct
cctgatgtggcaccccctcttctggtgaagctcgtggaggccactgagcggacaggactg
gacagcgaatcttactacaggctggagctgcccgccccgcgcacagactggtccctgagc
gacatggatcagtgggacgcgacagccctggcagacggcattaagggcttcctgctggcg
ctgcccgcacccctcgtgacacccgaggcctcggccgaggcgcgccgggccctgcgggag
gccgcggggcccctggggccgctgctggagcccccgacgctgccgctgcaccgcgccctc
acgctgcgcttcctgctgcagcacctgggccgcgtggcccgccgcgcccctgccttgggt
cccgcagtgcgggcgctgggcgccaccttcgggccgctgctgctacgcgcgccaccggcc
tcgccgcccccggggggcgcatcggacgggagtgagcccaaccctgacttcccggcactg
ctggtggagaagctgcttcgggaacatttggaagagcaggaagttgcgcccccagcgctg
ccgcctaaaccctccaagacaaagctggcccccgcaggcctagccaatggtgggagccca
cccgccttacaagacgctgagtggtactggggggacatctccagggaggaggtgaatgag
aaacttcgggacacgcctgatggcacctttcttgtccgagacgcatccagcaagatccaa
ggggagtacacgctgaccctcaggaaaggcgggaacaataagctgataaaggtcttccac
cgcgacgggcactatggcttctcggagccactcaccttctgctctgtcgtggacctcatc
aaccactaccgccacgagtcgctggcccagtataatgccaagctggacacgcggctcctc
tacccagtttccaagtaccagcaggaccagatcgtcaaggaggacagcgtggaggcggtg
ggcgcccagctcaaagtctaccaccagcaataccaggacaagagccgagagtacgaccag
ctctatgaggagtacacacgtacctcccaggagctacagatgaagcgcacagcaattgag
gccttcaacgagaccatcaagatcttcgaagagcagggagagacgcaggagaagtgcagc
aaggaatatctagagcgcttccggcgtgagggcaacgagaaggagatgcagaggatcctg
ctgaactcagagcggctcaagtctcgcatcgcggagatccatgagagccgcacaaagcta
gagcagcagctgcgggcgcaggcctcggacaaccgggagatcgacaagcgcatgaacagc
ctcaagccagacctcatgcagctgcgcaagatccgagaccagtacctcgtgtggctcacc
cagaaaggcgcccggcagaagaaaatcaacgagtggttggggatcaaaaacgagactgag
gaccagtacgcgctgatggaggatgaggacgatctcccccaccatgaggagcgcacgtgg
tacgtgggcaagatcaaccgcacgcaggctgaggaaatgctgagcggcaagcgggacggc
accttcctcatccgggagagcagccagcgcggctgttacgcttgctccgtggtggtggac
ggtgacaccaagcactgcgtcatctaccgcacggccactggcttcggcttcgcggagccc
tacaacctgtacgggtccctgaaggagctggtgctgcactaccagcacgcgtcgcttgtg
cagcacaacgacgcgcttgcagtcacccttgcgcacccggtgcgcgccccgggcccgggc
ccgccgcctgctgcccgctga
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