Lemur catta (Ring-tailed lemur): 123643895 Help Entry 123643895         CDS       T08326                                  Symbol CASP8 Name (RefSeq) caspase-8 isoform X1   KO K04398   caspase 8 [EC:3.4.22.61] Organism lcat  Lemur catta (Ring-tailed lemur) Pathway lcat01524   Platinum drug resistance lcat04115   p53 signaling pathway lcat04210   Apoptosis lcat04215   Apoptosis - multiple species lcat04217   Necroptosis lcat04620   Toll-like receptor signaling pathway lcat04621   NOD-like receptor signaling pathway lcat04622   RIG-I-like receptor signaling pathway lcat04623   Cytosolic DNA-sensing pathway lcat04625   C-type lectin receptor signaling pathway lcat04657   IL-17 signaling pathway lcat04668   TNF signaling pathway lcat04932   Non-alcoholic fatty liver disease lcat04936   Alcoholic liver disease lcat05010   Alzheimer disease lcat05016   Huntington disease lcat05022   Pathways of neurodegeneration - multiple diseases lcat05132   Salmonella infection lcat05134   Legionellosis lcat05142   Chagas disease lcat05145   Toxoplasmosis lcat05152   Tuberculosis lcat05160   Hepatitis C lcat05161   Hepatitis B lcat05162   Measles lcat05163   Human cytomegalovirus infection lcat05164   Influenza A lcat05165   Human papillomavirus infection lcat05167   Kaposi sarcoma-associated herpesvirus infection lcat05168   Herpes simplex virus 1 infection lcat05169   Epstein-Barr virus infection lcat05170   Human immunodeficiency virus 1 infection lcat05200   Pathways in cancer lcat05203   Viral carcinogenesis lcat05416   Viral myocarditis lcat05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:lcat00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     123643895 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     123643895 (CASP8)    04215 Apoptosis - multiple species     123643895 (CASP8)    04217 Necroptosis     123643895 (CASP8)    04115 p53 signaling pathway     123643895 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     123643895 (CASP8)    04621 NOD-like receptor signaling pathway     123643895 (CASP8)    04622 RIG-I-like receptor signaling pathway     123643895 (CASP8)    04623 Cytosolic DNA-sensing pathway     123643895 (CASP8)    04625 C-type lectin receptor signaling pathway     123643895 (CASP8)    04657 IL-17 signaling pathway     123643895 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     123643895 (CASP8)    05203 Viral carcinogenesis     123643895 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     123643895 (CASP8)    05161 Hepatitis B     123643895 (CASP8)    05160 Hepatitis C     123643895 (CASP8)    05164 Influenza A     123643895 (CASP8)    05162 Measles     123643895 (CASP8)    05168 Herpes simplex virus 1 infection     123643895 (CASP8)    05163 Human cytomegalovirus infection     123643895 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     123643895 (CASP8)    05169 Epstein-Barr virus infection     123643895 (CASP8)    05165 Human papillomavirus infection     123643895 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     123643895 (CASP8)    05134 Legionellosis     123643895 (CASP8)    05152 Tuberculosis     123643895 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     123643895 (CASP8)    05142 Chagas disease     123643895 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     123643895 (CASP8)    05016 Huntington disease     123643895 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     123643895 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     123643895 (CASP8)    05416 Viral myocarditis     123643895 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     123643895 (CASP8)    04932 Non-alcoholic fatty liver disease     123643895 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     123643895 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:lcat01002]     123643895 (CASP8) Enzymes [BR:lcat01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      123643895 (CASP8) Peptidases and inhibitors [BR:lcat01002]  Cysteine peptidases   Family C14: caspase family    123643895 (CASP8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 DED PYRIN DUF3993 Motif Other DBs NCBI-GeneID:  123643895 NCBI-ProteinID:  XP_045415699 LinkDB All DBs Position 8:complement(30733192..30761894) Genome browser AA seq 479 aa AA seqDB search MDFSSSLYSIGEEIDSDELASLKFLSLDHIPQRKQEPIKDALMLFERLQEKRMLEESNLS FLKELLFHINRLDLLLTYLGTSREEMERELQTPGRAQISAYRVMLFQISEEVSKAQLRTF KFFLSQDISKCKLEDDMSLLDIFIEMEKRVILGERNLDTLKRVFGKINKSLLKKINDYEE LSRERRLSLERSSDEFSNGEETFRMLEISDSPREQDGDSQTSDKVYRMQSKPRGYCLIFN NYDFSTARKAVDKLQRIRDRNGTHLDKDALSKTFNELHFEVVHFEDSTAKEIHEVLKVYQ GMDHNNKDCFICCILSHGDKGIIYGTDGEEVSIYELTSYFTGSNCPSLAGKPKVFFIQAC QGDNYQKGIPVETDSEQKEAYLEMDVSLQKRYIPDEADFLLGMATVNNCVSYRNPAEGTW YIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDRKHMGKQMPQPSFTLRKKLFFPLN NT seq 1440 nt NT seq  +upstreamnt  +downstreamnt atggatttcagtagcagtctctacagtattggggaagaaatagacagtgatgagttggcc tccctgaagttcctaagcctggaccacatcccacaaaggaagcaggaacccatcaaggac gccttgatgttattcgagagactccaggaaaagagaatgttggaggaaagcaacctgtcc ttcctgaaggagctgctcttccatattaaccgactggatctcctgcttacttacctgggt actagcagggaggagatggagagagaacttcagacccctggcagggctcaaatttctgcc tacagggtcatgctttttcagatttcagaagaagtatctaaagcgcaattgagaactttt aagttttttttgagccaggacatctccaaatgtaaactggaagatgacatgagcttgctc gatattttcatagaaatggagaagagggtcatcctaggggaaagaaacttggacaccctg aaaagagtcttcggcaaaatcaacaagagcctgctgaagaaaatcaatgattatgaagaa ttaagcagagagagaagattgagccttgaaagatcatcagatgaattttcaaatggggag gagacattcagaatgctggaaatatcagactctccaagagaacaagacggtgattcacag acatctgacaaagtttacagaatgcaaagcaaacctcggggatactgtttgatcttcaac aactatgattttagcacagcacggaaggcagtggacaaacttcaaagaattagggatagg aatggcacccacttggataaagatgctttaagcaagacctttaatgagcttcattttgag gtagtacattttgaagactccacagcaaaagaaatccatgaggttctgaaggtctaccaa ggcatggaccacaataacaaagactgcttcatctgctgcatcctctcccacggagacaag ggcatcatctatggcactgatggagaggaggtctccatctatgagctgacatcttatttc actggttcgaactgcccttctcttgctggaaaacccaaagtcttttttattcaggcttgt caaggggataattaccagaaaggaataccagttgagactgactcagagcagaaggaagcc tatttagaaatggacgtatcacttcaaaagagatatatcccagatgaggctgactttctg ctggggatggctactgtgaacaactgtgtttcctaccgaaaccctgcagaggggacctgg tatatccagtcactttgccagagcctgagagaaagatgtcctcgaggtgacgatattctc accatcctgactgaagtgaactatgaagtgagcaacaaggatgacaggaaacacatgggg aaacagatgccacagccttccttcactctgaggaaaaaacttttctttccccttaattga

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