Lemur catta (Ring-tailed lemur): 123647256 Help Entry 123647256         CDS       T08326                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism lcat  Lemur catta (Ring-tailed lemur) Pathway lcat00230   Purine metabolism lcat01100   Metabolic pathways lcat01522   Endocrine resistance lcat04015   Rap1 signaling pathway lcat04020   Calcium signaling pathway lcat04022   cGMP-PKG signaling pathway lcat04024   cAMP signaling pathway lcat04062   Chemokine signaling pathway lcat04072   Phospholipase D signaling pathway lcat04081   Hormone signaling lcat04082   Neuroactive ligand signaling lcat04114   Oocyte meiosis lcat04211   Longevity regulating pathway lcat04213   Longevity regulating pathway - multiple species lcat04261   Adrenergic signaling in cardiomyocytes lcat04270   Vascular smooth muscle contraction lcat04371   Apelin signaling pathway lcat04540   Gap junction lcat04611   Platelet activation lcat04713   Circadian entrainment lcat04714   Thermogenesis lcat04720   Long-term potentiation lcat04723   Retrograde endocannabinoid signaling lcat04724   Glutamatergic synapse lcat04725   Cholinergic synapse lcat04727   GABAergic synapse lcat04750   Inflammatory mediator regulation of TRP channels lcat04911   Insulin secretion lcat04912   GnRH signaling pathway lcat04913   Ovarian steroidogenesis lcat04914   Progesterone-mediated oocyte maturation lcat04915   Estrogen signaling pathway lcat04916   Melanogenesis lcat04918   Thyroid hormone synthesis lcat04921   Oxytocin signaling pathway lcat04923   Regulation of lipolysis in adipocytes lcat04925   Aldosterone synthesis and secretion lcat04926   Relaxin signaling pathway lcat04927   Cortisol synthesis and secretion lcat04928   Parathyroid hormone synthesis, secretion and action lcat04934   Cushing syndrome lcat04935   Growth hormone synthesis, secretion and action lcat04970   Salivary secretion lcat04971   Gastric acid secretion lcat04972   Pancreatic secretion lcat04976   Bile secretion lcat05032   Morphine addiction lcat05142   Chagas disease lcat05146   Amoebiasis lcat05163   Human cytomegalovirus infection lcat05166   Human T-cell leukemia virus 1 infection lcat05200   Pathways in cancer lcat05207   Chemical carcinogenesis - receptor activation lcat05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lcat00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     123647256 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     123647256 (ADCY1)    04371 Apelin signaling pathway     123647256 (ADCY1)    04020 Calcium signaling pathway     123647256 (ADCY1)    04072 Phospholipase D signaling pathway     123647256 (ADCY1)    04024 cAMP signaling pathway     123647256 (ADCY1)    04022 cGMP-PKG signaling pathway     123647256 (ADCY1)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     123647256 (ADCY1)    04081 Hormone signaling     123647256 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     123647256 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     123647256 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     123647256 (ADCY1)    04062 Chemokine signaling pathway     123647256 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     123647256 (ADCY1)    04923 Regulation of lipolysis in adipocytes     123647256 (ADCY1)    04912 GnRH signaling pathway     123647256 (ADCY1)    04913 Ovarian steroidogenesis     123647256 (ADCY1)    04915 Estrogen signaling pathway     123647256 (ADCY1)    04914 Progesterone-mediated oocyte maturation     123647256 (ADCY1)    04921 Oxytocin signaling pathway     123647256 (ADCY1)    04926 Relaxin signaling pathway     123647256 (ADCY1)    04935 Growth hormone synthesis, secretion and action     123647256 (ADCY1)    04918 Thyroid hormone synthesis     123647256 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     123647256 (ADCY1)    04916 Melanogenesis     123647256 (ADCY1)    04925 Aldosterone synthesis and secretion     123647256 (ADCY1)    04927 Cortisol synthesis and secretion     123647256 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     123647256 (ADCY1)    04270 Vascular smooth muscle contraction     123647256 (ADCY1)   09154 Digestive system    04970 Salivary secretion     123647256 (ADCY1)    04971 Gastric acid secretion     123647256 (ADCY1)    04972 Pancreatic secretion     123647256 (ADCY1)    04976 Bile secretion     123647256 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     123647256 (ADCY1)    04727 GABAergic synapse     123647256 (ADCY1)    04725 Cholinergic synapse     123647256 (ADCY1)    04720 Long-term potentiation     123647256 (ADCY1)    04723 Retrograde endocannabinoid signaling     123647256 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     123647256 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     123647256 (ADCY1)    04213 Longevity regulating pathway - multiple species     123647256 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     123647256 (ADCY1)    04714 Thermogenesis     123647256 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     123647256 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     123647256 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     123647256 (ADCY1)    05163 Human cytomegalovirus infection     123647256 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     123647256 (ADCY1)    05142 Chagas disease     123647256 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     123647256 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     123647256 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     123647256 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     123647256 (ADCY1) Enzymes [BR:lcat01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      123647256 (ADCY1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom Motif Other DBs NCBI-GeneID:  123647256 NCBI-ProteinID:  XP_045420526 LinkDB All DBs Position 11:89044492..89192441 Genome browser AA seq 1119 aa AA seqDB search MAGAPRGGGGGGGGAGEPGGAERAAGPGGRRGLRVCNEEFACPELEALFRGYTLRLEQAA TLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQLQ QVGQLALFFSLTFALLCCPFALGGPARGSAGAAGGPATAEQGVWQLLLVTFVSYALLPVR SLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFVGVNMYGVFVRILTERSQR KAFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHD NVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGL TQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWS NDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGYGHERNSFLKAHNIETFFIVPSH RRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALR TASEKLRNRSSFSTNVVYTTPGTRVNRYISRLLEARQTELEMADLNFFTLKYKHVEREQK YHQLQDEYFTSAVVLALILAALFGLVYLLIIPQSVAVLLLLVFSICFLVACVLYLHITRV QCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWNSKPNSTLVVFSSGGRRTALP ALPCESAHHALLCCLVGTLPLAIFLRVSSLPKMILLLGLTTSYILVLELSGYTRSGGGAV SGRSYEPIMAILLFSCALALHARQVDVRLRLDYLWAAQAEEEREDMERVKLDNRRILFNL LPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEI IADFDKLMDKDFYKDLEKIKTIGSTYMAAVGLAPTSGAKAKKSISSHLSTLADFAIEMFD VLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQV TEEVHRLLRRCSYHFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQTRPLGLERKMCPYGRA GLQARHPPVCPTAGLPVRAGLPPHPTSQYLPPMAAGKEA NT seq 3360 nt NT seq  +upstreamnt  +downstreamnt atggcgggggcgccgcgcggcggaggcggcggcggaggcggcgcgggcgagcctgggggc gccgagcgggcggccgggccaggcggccggcgcgggctccgggtgtgcaacgaggagttc gcttgccccgagctggaggcgctgttccgcggctacacgctgcggctggagcaggcggcc acgctgaaggcgctggcggtgctcagcctgctggcgggcgcgctggcactggccgagctg ctgggcgcgccggggccggcgcccggcctggccaagggctcgcaccccgtgcactgcgtc ctcttcttggcgctgctcgtggtcaccaatgtccggtccctgcaggtgccccagctgcag caggtcggccagctggcgctgttcttcagcctcaccttcgcgttgctctgctgccccttt gcgctgggcggccccgcccggggctccgccggggcggccgggggaccggcgaccgcggaa cagggtgtttggcagctccttttggtcaccttcgtgtcctatgccctgctgcccgtgcgc agcctgctggccatcggcttcgggctcgtggtggctgcctcacacttgctggttacagcc accttggtccccgccaagcgcccacgtctctggaggacgctcggtgccaacgccttgctg ttcgttggcgtgaacatgtatggggtcttcgtgcggatcctgaccgagcgctcacagagg aaggcgttcctgcaggcccggagctgcatcgaggaccggctgaggctggaggatgagaac gagaagcaggagcggctcctcatgagcctcctgccacggaatgttgccatggagatgaag gaggacttcctgaagccccccgagaggattttccacaagatttacatccagaggcatgac aatgtgagcatcctgtttgcagacatcgtgggcttcacgggcttggcgtcccagtgcacg gcccaggagctggtgaaactcctcaatgagctttttggcaagttcgacgaattagccaca gagaaccactgtcgccgcatcaagatccttggggactgctactactgtgtgtcgggcctc acccagcccaagaccgaccacgcccactgctgcgtggagatggggctcgacatgatcgac accatcacgtccgtggccgaggccaccgaagtggacctgaacatgcgtgtgggtctgcac acgggcagggtcctctgtggcgtcctgggcctgcgcaagtggcagtatgatgtgtggtcc aacgatgtgaccctggccaacgttatggaagccgctggcctacctgggaaggttcatatc acaaagacgaccctcgcatgcttgaatggggactacgaggtagaaccaggttatggacat gagaggaacagtttcctgaaagctcataatatcgaaaccttttttattgtgccatcccat cgcagaaagatatttccaggcctgattctctcagatataaaaccggcaaagaggatgaag ttcaagaccgtctgctacctgctggtgcagctcatgcactgccggaagatgttcaaggcc gagatccccttctccaatgtcatgacctgcgaggatgatgacaagcggagggcgttgaga acagcctcggaaaagctcagaaaccgctcgtccttctctaccaacgttgtctacaccacc ccaggcactcgtgtcaacaggtacatcagccgcctcctagaagcccgccagacagagctg gagatggcggacctgaacttcttcaccctgaagtacaagcatgtcgaacgggagcaaaag taccaccagcttcaggacgagtatttcaccagcgctgttgtcctcgccctcatcctggct gccttatttggccttgtctaccttctaataatcccacagagtgtggccgtcctgctcctg ttagtgttctccatttgcttcctggtggcctgtgtcctgtacctacacatcacccgggtc cagtgttttccagggtgcctgacgattcagattcgcactgtcttgtgtattttcatagtg gtcttaatctactcggtagcccaaggatgtgtggtgggctgcctgccctgggcctggaac tccaagcccaacagtaccctggtggtcttctcctctgggggccggcgcacagcgctgccc gccctgccctgcgagtctgcacaccacgccctgctctgctgcctggtgggcaccctcccg ctagccatattcctgcgggtgtcctccttgccaaaaatgatcctgctgttggggctcacc acgtcctacatcctcgtcctggagctcagcggatacaccagatctgggggcggtgctgtc tctgggcgcagctacgagccgatcatggccatcctgctgttctcctgcgcgctggccctg catgccaggcaggtggacgtcaggctgcggctggactacctctgggcggcgcaggcagaa gaggagcgcgaggacatggagcgggtgaagctggacaacaggaggatcctcttcaacctc ctgccggcccacgtcgcccagcacttcctcatgtccaacccccggaacatggacctctac taccagtcctactcccaggtgggtgtcatgttcgcctctatccccaacttcaatgacttc tacatcgagctggatggcaacaacatgggggtggagtgtctgcggctgctcaacgagatc atcgccgactttgacaagctcatggacaaagacttttacaaggacctagagaagatcaaa accattgggagcacctacatggccgcggtggggctggcgcccacctcgggggccaaggcc aagaagtccatctcctcccacctaagcacactggcggactttgccattgagatgtttgat gtcctggatgagatcaactaccagtcttacaacgacttcgtcctgcgagttggcatcaac gtgggccccgtggtggccggagtgatcggggctcgcaggccccagtatgacatctgggga aacacagtcaacgtggccagtcggatggacagcaccggggtccagggaagaatccaggtg actgaggaagtccaccggctgctgagaaggtgctcctaccacttcgtgtgcagaggcaaa gtcagtgtcaagggcaagggcgagatgttgacatactttttggaaggcaggactgatgga aacggctcccagaccaggcccctaggcttagagcgaaaaatgtgtccttatgggagagcc ggccttcaggccagacacccccctgtgtgccccacggctgggctcccagtcagggccggg ctccccccgcaccccaccagccagtacctgccccccatggcagctgggaaggaggcttaa

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