Lemur catta (Ring-tailed lemur): 123648063 Help Entry 123648063         CDS       T08326                                  Symbol ADCY2 Name (RefSeq) adenylate cyclase type 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism lcat  Lemur catta (Ring-tailed lemur) Pathway lcat00230   Purine metabolism lcat01100   Metabolic pathways lcat01522   Endocrine resistance lcat04015   Rap1 signaling pathway lcat04020   Calcium signaling pathway lcat04022   cGMP-PKG signaling pathway lcat04024   cAMP signaling pathway lcat04062   Chemokine signaling pathway lcat04072   Phospholipase D signaling pathway lcat04081   Hormone signaling lcat04082   Neuroactive ligand signaling lcat04114   Oocyte meiosis lcat04211   Longevity regulating pathway lcat04213   Longevity regulating pathway - multiple species lcat04261   Adrenergic signaling in cardiomyocytes lcat04270   Vascular smooth muscle contraction lcat04371   Apelin signaling pathway lcat04540   Gap junction lcat04611   Platelet activation lcat04713   Circadian entrainment lcat04714   Thermogenesis lcat04723   Retrograde endocannabinoid signaling lcat04724   Glutamatergic synapse lcat04725   Cholinergic synapse lcat04727   GABAergic synapse lcat04750   Inflammatory mediator regulation of TRP channels lcat04911   Insulin secretion lcat04912   GnRH signaling pathway lcat04913   Ovarian steroidogenesis lcat04914   Progesterone-mediated oocyte maturation lcat04915   Estrogen signaling pathway lcat04916   Melanogenesis lcat04918   Thyroid hormone synthesis lcat04921   Oxytocin signaling pathway lcat04922   Glucagon signaling pathway lcat04923   Regulation of lipolysis in adipocytes lcat04925   Aldosterone synthesis and secretion lcat04926   Relaxin signaling pathway lcat04927   Cortisol synthesis and secretion lcat04928   Parathyroid hormone synthesis, secretion and action lcat04934   Cushing syndrome lcat04935   Growth hormone synthesis, secretion and action lcat04970   Salivary secretion lcat04971   Gastric acid secretion lcat04972   Pancreatic secretion lcat04976   Bile secretion lcat05032   Morphine addiction lcat05163   Human cytomegalovirus infection lcat05166   Human T-cell leukemia virus 1 infection lcat05200   Pathways in cancer lcat05207   Chemical carcinogenesis - receptor activation lcat05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:lcat00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     123648063 (ADCY2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     123648063 (ADCY2)    04072 Phospholipase D signaling pathway     123648063 (ADCY2)    04024 cAMP signaling pathway     123648063 (ADCY2)    04022 cGMP-PKG signaling pathway     123648063 (ADCY2)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     123648063 (ADCY2)    04081 Hormone signaling     123648063 (ADCY2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     123648063 (ADCY2)    04062 Chemokine signaling pathway     123648063 (ADCY2)   09152 Endocrine system    04911 Insulin secretion     123648063 (ADCY2)    04922 Glucagon signaling pathway     123648063 (ADCY2)    04923 Regulation of lipolysis in adipocytes     123648063 (ADCY2)    04913 Ovarian steroidogenesis     123648063 (ADCY2)    04915 Estrogen signaling pathway     123648063 (ADCY2)    04921 Oxytocin signaling pathway     123648063 (ADCY2)    04926 Relaxin signaling pathway     123648063 (ADCY2)    04935 Growth hormone synthesis, secretion and action     123648063 (ADCY2)    04918 Thyroid hormone synthesis     123648063 (ADCY2)    04928 Parathyroid hormone synthesis, secretion and action     123648063 (ADCY2)    04925 Aldosterone synthesis and secretion     123648063 (ADCY2)    04927 Cortisol synthesis and secretion     123648063 (ADCY2)   09154 Digestive system    04970 Salivary secretion     123648063 (ADCY2)    04971 Gastric acid secretion     123648063 (ADCY2)    04972 Pancreatic secretion     123648063 (ADCY2)    04976 Bile secretion     123648063 (ADCY2)   09156 Nervous system    04724 Glutamatergic synapse     123648063 (ADCY2)    04727 GABAergic synapse     123648063 (ADCY2)    04725 Cholinergic synapse     123648063 (ADCY2)    04723 Retrograde endocannabinoid signaling     123648063 (ADCY2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     123648063 (ADCY2)   09149 Aging    04211 Longevity regulating pathway     123648063 (ADCY2)    04213 Longevity regulating pathway - multiple species     123648063 (ADCY2)   09159 Environmental adaptation    04713 Circadian entrainment     123648063 (ADCY2)    04714 Thermogenesis     123648063 (ADCY2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     123648063 (ADCY2)    05207 Chemical carcinogenesis - receptor activation     123648063 (ADCY2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     123648063 (ADCY2)    05163 Human cytomegalovirus infection     123648063 (ADCY2)   09165 Substance dependence    05032 Morphine addiction     123648063 (ADCY2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     123648063 (ADCY2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     123648063 (ADCY2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     123648063 (ADCY2) Enzymes [BR:lcat01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      123648063 (ADCY2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N HNOBA Motif Other DBs NCBI-GeneID:  123648063 NCBI-ProteinID:  XP_045421742 LinkDB All DBs Position 12:4550053..4915275 Genome browser AA seq 1094 aa AA seqDB search MWQEAMRRRRYLRDRAEAVAAAAGGGDGLPRSRDWLYESYYCMSQQHPLIVFLLLIVMGS CLALLALFFAFGLEVEDHVAFLITVPTALAIFFAIFILVCIESVFKKLLRLFSLVIWICL VTMAYLFLCFEGTISPWDQVSFFLFIIFVVYTMLPFNMRDAIIASVLTSASHTIVLSVCL SSTPEAKEHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKLEFEK RQQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYADIV GFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKN CVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHME AGGVPGRVHISSVTLEHLNGAYKVEEGDGDVRDPYLKQHLVKTYFVINPKGERRSPQHLF RPRHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQHNFQN RTLRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKILEKEYRATAL PAFKYYVTCACLIFFCIFIVQILVLPKTSTFGISFGAAFLLLAFILFVCFAGQLLQCSKK ASPLLMWLLKSSGIITNRFWPRIFLTVVTTAIVLTMAVFNMFFLSDSEETILPTANISNT SFSASNNQAVILRAQSLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMVALVGYNIIL LHTHAHVLGDYSHVLFERPGIWKDLKTMGSVSLSIFFVTLLVLGRQNEYYCRLDFLWKNK FKKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEDLYHQSYDCVCVMFASIPDFK EFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQ EHAQEPERQYMHIGTMVEFAFALVAKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQ YDIWGNTVNVASRMDSTGVMDKIQVTEETSLILQTLGYTCTCRGIINVKGKGDLKTYFVN TEMSRSLSQSNLAS NT seq 3285 nt NT seq  +upstreamnt  +downstreamnt atgtggcaggaggcgatgcggcgccgccgctacctgcgggaccgcgccgaggctgtggcg gcggcggcgggcggcggagacgggctgcctcggtcccgggactggctgtacgagtcctac tactgcatgagccagcagcacccgctcatcgtcttcctgctgctcatcgtcatgggttcc tgcctcgccctgcttgccctcttcttcgccttcgggctggaagttgaagaccatgtggca tttttaataacggttccaacggccctggcgattttctttgcgatatttatcctcgtctgc atcgagtctgtgtttaagaagctgctgcgcctcttctctttggtgatatggatctgtctc gtcaccatggcctacttgttcctgtgctttgaaggcaccatctctccctgggaccaggta tcattcttcctcttcattatcttcgtggtgtacaccatgctgcccttcaacatgcgagat gccatcatcgccagcgtcctcacctccgcttcccacaccatcgtgctgagtgtctgcctg tcttcaactccggaggccaaggagcacctggtctggcagatcctggccaacgtgatcatt ttcatctgcgggaacctggcgggagcgtaccacaagcacctcatggaacttgctctgcag cagacatatcaggacacgtgcaattgcatcaagtcccggatcaagttggaatttgaaaaa cgtcagcaggagcggctgctgctgtccctgctgccggcgcacatagccatggagatgaag gccgagatcatccaacggctgcagggccccaaagcgggccagatggaaaacacaaacaac tttcacaacctgtacgtcaaacgacacaccaatgtgagcatcttatacgcggacatcgtt ggcttcacccggctggcgagcgactgctccccaggagaacttgtccacatgctgaacgaa ctctttggcaagtttgatcagattgcaaaggagaacgaatgcatgagaattaaaatttta ggagattgctactactgtgtgtcgggactccctatctctctccccaaccacgccaaaaac tgtgtgaaaatgggactggatatgtgtgaagccataaagaaggtaagggacgctaccggc gttgacatcaacatgcgcgtgggcgtgcactctgggaatgtcctgtgcggcgtgattggt ctgcagaagtggcagtacgatgtgtggtcacatgacgttaccctggccaaccacatggaa gctggaggggtccctggacgtgtccacatttcttctgtcaccctggagcacttgaatggg gcctacaaagtggaggagggagacggtgacgtcagggacccctacttaaaacagcacctg gtgaagacctacttcgtgatcaaccccaagggagaacgacggagtccccaacacctcttc agaccgcgccacaccctggatggagccaagatgagggcgtccgtccgcatgacccggtac ttggagtcctggggggcggccaagccttttgcacacctgcatcacagggacagcatgacc acagagaacggcaagatcagcaccacggatgtaccaatgggtcagcataattttcaaaac cgcaccttaagaaccaagtcacaaaagaaaagatttgaagaagaattgaatgaaaggatg attcaagcaattgatggaatcaatgcacaaaagcaatggctcaagtctgaagatattcag agaatctcactgcttttttataacaaaatactagaaaaagaataccgagccaccgcactg ccagcgttcaagtactacgtgacttgcgcttgtctcatattcttctgcatctttatcgtg cagattctcgtattaccaaaaacatccaccttcgggatttcctttggagccgcgtttctc ttgcttgccttcatcctcttcgtctgctttgctggacagcttttgcaatgcagcaaaaaa gcctctccccttctcatgtggcttttgaagtcctcaggcatcatcaccaaccgtttctgg cctcggatctttctcaccgttgtcaccacagccatcgtattgaccatggccgtgttcaac atgtttttcctgagtgactcagaggaaacaatccttccaactgccaatatatcaaacaca agtttttctgcctcaaataatcaggcagtgattctgcgtgcgcaaagtttatttttcctc ccgtactttatctacagctgcattctgggcctgatatcctgttcggtgttcctgcgggtg aattacgagttgaaaatgttgatcatgatggtggcgttggtgggttacaacatcatcctg ctccacacccatgcccacgtcctgggtgattacagccacgtcctgtttgagagaccaggc atttggaaagacctaaagaccatgggctctgtgtctctctctatattcttcgtcacactg cttgtcctgggtagacagaatgaatattactgtaggttagacttcttatggaagaacaag ttcaaaaaagagcgggaggagatagagacgatggagaacctgaaccgcgtgctgctggag aacgtgcttcccgcgcacgtcgccgagcacttcctggccaggagcctgaagaacgaggac ttataccaccagtcctatgactgcgtctgcgtcatgtttgcctccattcctgacttcaag gaattttatacggaatcagatgtgaacaaggagggcttggaatgccttcggctcctgaat gagatcatcgccgactttgacgatctgctgtccaagccgaaattcagtggagttgaaaag atcaagaccatcggcagcacatacatggcagcgacgggtctgagcgccgtgcccagccag gagcacgcccaggagcccgagcggcagtacatgcacatcggcaccatggtggaatttgct tttgccctggtggccaaactggatgccatcaacaagcactccttcaacgacttcaaactg cgagtgggtatcaaccacgggcctgtgatagccggtgtgattggcgcccagaagccacag tacgacatctggggcaacaccgtcaacgtggccagtcggatggacagcaccggcgtcatg gacaaaatacaggtcactgaggaaacgagcctcatcctgcagacgctcgggtacacatgc acgtgtcgaggaatcatcaacgtgaaaggaaagggagacctgaagacatactttgtaaac acagaaatgtcaaggtccctctcccagagcaacctggcatcttga

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