Lemur catta (Ring-tailed lemur): 123648877 Help Entry 123648877         CDS       T08326                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism lcat  Lemur catta (Ring-tailed lemur) Pathway lcat04022   cGMP-PKG signaling pathway lcat04068   FoxO signaling pathway lcat04081   Hormone signaling lcat04140   Autophagy - animal lcat04152   AMPK signaling pathway lcat04211   Longevity regulating pathway lcat04213   Longevity regulating pathway - multiple species lcat04910   Insulin signaling pathway lcat04920   Adipocytokine signaling pathway lcat04923   Regulation of lipolysis in adipocytes lcat04930   Type II diabetes mellitus lcat04931   Insulin resistance lcat04932   Non-alcoholic fatty liver disease lcat04935   Growth hormone synthesis, secretion and action lcat05010   Alzheimer disease lcat05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:lcat00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     123648877 (IRS2)    04022 cGMP-PKG signaling pathway     123648877 (IRS2)    04152 AMPK signaling pathway     123648877 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     123648877 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     123648877 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04923 Regulation of lipolysis in adipocytes     123648877 (IRS2)    04935 Growth hormone synthesis, secretion and action     123648877 (IRS2)   09149 Aging    04211 Longevity regulating pathway     123648877 (IRS2)    04213 Longevity regulating pathway - multiple species     123648877 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     123648877 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     123648877 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     123648877 (IRS2)    04932 Non-alcoholic fatty liver disease     123648877 (IRS2)    04931 Insulin resistance     123648877 (IRS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N Motif Other DBs NCBI-GeneID:  123648877 NCBI-ProteinID:  XP_045422730 LinkDB All DBs Position 13:13488355..13518995 Genome browser AA seq 1337 aa AA seqDB search MASPPLHGPPGPASGDGPNLNNNNNNNHGVRKCGYLRKQKHGHKRFFVLRGPGAGSDEAT ATAGGGSAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKD EYFAVAAENEQEQEGWYRALTDLVSEGRAGAGDAPPNAAATSGSCSASLPGALGGSAGAA GADDNYGLVSPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSV TLQLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELF EFRPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSS CRVRTASEGDGGAAAGTGAAGGRPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVTL APAGGALQHSRSMSMPVAHSPPTATSPGSLSSSSGHGSGSYPPPPGPHPHLPHPLHHPPG QRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGSGAEL YGYMTMDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYT LMRATFSGSSGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPG VAVLGSGGGSCKSDDYMPMSPTSVSAPKQILQPRAAPAALPPTGSAVPAPTSVASRTFAG NGGSYKTSSPAESSPEDSGYMRMWCGSKLSVENADSKLLSNGDYLNMSPSDAGTSGTPPD FFSAALHAGGEMLKGVPGYCYSSLPRSYKAPYTCGGGNDQYVLMSAPVGRILEEERLEPQ ASPGTTPSASAFGAGGGGHTQPHHPVVPSPVRPSGSGRPEGFLSQRCRAVRPTRLSLEGL QTLPSMHEYPLPPEPKSPGEYINIDFGEAGARLSPPAPPLLASAASSCSLLSAGSPASSL GSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGTQSADPVGSLDALLSPEAASPYPPLP PRPPASPASLQQPPPPPPPGELYRLPPASAVATTQGPGTASSLSSETGDNGDYTEMAFGV AATPPQPIAAPPKPEGARVTSPTSGVKRLSLMDQVSGVEAFLQASQPPDPHRGAKVIRAD PQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKGSEGSGGVLGGGPGG GEEAPMSPRQLQPSLPVPSLPPQARPRAPAPPGGLVGCPGGSGSPMRRETSAGFQNGLNY IAIDVRDEPGLTQPQPQPGDKSSWGRTRSLGGLISAVGSGSSGVCGGPGPGALPSANTYA SIDFLSHHLKEATIVKE NT seq 4014 nt NT seq  +upstreamnt  +downstreamnt atggccagcccgccgctgcacgggcccccggggccggcgagcggagacggccccaacctc aacaacaacaacaacaacaaccacggcgtgcgcaagtgcggctacctgcgcaagcagaag cacggccacaagcgcttcttcgtgctgcgcgggcccggcgcgggcagcgacgaagcgaca gcgacagcgggcggggggtcggcgccgcagccgccgaggctcgagtactatgagagcgag aagaagtggcggagcaaggcgggcgccccgaaacgggtgatcgcgctcgactgctgcctg aacatcaacaagcgcgcggacgccaagcacaagtacctgatcgccctctacaccaaggac gagtactttgcggtggcggcagagaacgagcaggagcaggagggctggtatcgcgcgctc acagacttggtcagcgagggccgcgcgggtgctggcgacgcgccccccaacgccgcggcc acctccgggtcctgcagcgcctccttgccgggcgccctgggcggctcagccggcgccgcc ggggccgatgacaactacgggctggtgtcgcccgccacggccgcctaccgcgaggtgtgg caggtgaacctgaagcccaagggtctgggccagagcaagaacctgacgggcgtgtaccgc ctgtgcctgtcggcgcgcaccataggcttcgtgaagctcaactgcgagcagccgtcggtg acgctgcagctcatgaacatccgccgctgcggccactccgacagcttcttcttcattgag gtgggccgctcagcggtcactggccccggcgagctgtggatgcaggccgacgactcggtg gtggcgcagaacatccatgagaccatcctggaggccatgaaggcgctcaaggagctcttc gagttccggccgcgcagcaagagccagtcgtcagggtcgtcagccacgcacccgatcagt gtccccggcgcgcggcgccaccaccacctggtcaacctgccccccagtcagaccgggctg gtgcgccgctcccgcaccgacagtctggccgccaccccgccggccgccaagtgcagctca tgtcgagtgcgcacagccagcgagggcgacggtggcgcggcagcggggaccggggctgcg ggcggcaggccggtgtcggtggccgggagccccctgagccccgggccggtgcgcgcgccc ctgagccgctcgcacaccctgagcggcggctgcggtggccgcgggagcaaagtgacgctg gcgccggcagggggcgccctgcaacacagccgctccatgtccatgccggtggcgcactcg cccccgaccgccaccagcccgggcagcttgtcgtctagcagcgggcacggctcgggctcc tacccgccgcctccgggtccccacccgcacctgccgcaccccctgcaccaccccccaggg cagcggccctccagcggcagcgcctcagcctccggctcccccagcgaccccggcttcatg tccctggacgagtatggctccagccctggcgacctgagagcgttctgtagccacaggagc aacacgcccgagtctatcgccgagacccccccggccagggacggcagcggggccgagctg tacgggtacatgaccatggacaggcccctgagccactgtggccgcccctaccgcagagtc tcaggggacggggcccaggacttggacagagggctgaggaagaggacttactccctgacc acacctgcccggcagcggccggtgccccagccctcttctgcctctttggatgaatacacc ctgatgcgggccaccttctccggcagctcaggccgcctgtgcccgtcgtgccccgcatct tctcccaaagtggcctaccacccctacccggaggactatggggacatcgagattggatcc cacaggagctccagcagtaatctaggggcggacgatggttacatgcccatgacccctggc gtggccgtcttgggcagtggcggtggcagctgcaagagcgatgattacatgcccatgagc cccaccagcgtgtctgccccaaagcagattctgcagcccagggcggcccctgcagccttg cctcccacaggaagcgctgtgccagcgcccacctctgtggccagcaggacctttgcaggg aacgggggcagctacaagaccagctcccctgcggagagctcccccgaggacagtgggtac atgcggatgtggtgtggttccaagctgtccgtggagaatgctgacagcaagctgctttcc aacggggactatctcaacatgtcccccagcgacgcgggcacctccggtactccacccgac ttcttctctgcagccttgcacgccgggggcgagatgctcaaaggcgtccctggctactgc tacagctctctgccccgctcctacaaggccccgtacacctgcggcgggggcaacgaccag tatgtgctcatgagcgcccccgtggggcggatcctggaagaagagaggctggagccgcag gccagcccggggaccactccctctgccagcgcttttggggctggtgggggtggccacacc cagcctcatcacccagtagtgccttcgcctgtgaggccgagtggcagcggccgcccagag ggcttcctgagccagcgctgtcgagccgtgaggcccacgcggctgtccctggaggggctg cagaccctgcccagcatgcacgagtaccctctgccgccagagcccaagagccccggcgag tacatcaacattgactttggcgaggcgggagcccgcctgtcgccgcctgcccctccgctg ctggcgtcggcggcctcgtcctgctcgctgctgtccgctggcagcccggcttcgtccctg ggctcgggcacgccgggcaccagcagcgacagccggcagcgctccccgctctccgactac atgaacctcgacttcagctcgcccaagtcacccaagccgggcacccagagcgcggacccc gtgggctctttggacgccctcctttcccccgaggccgcctctccatacccgccgctgccc ccacgccctcccgcctcgccagcgtccctgcagcagccgccgcccccgccgcccccaggg gagctctaccgcctgcctccagcttcagctgtggccaccacccagggccctggcactgcc tcgtcattgtcctccgagactggggacaatggtgactacaccgagatggcctttggcgtg gctgccaccccgccacaacccatcgcggcccctccaaagccggaaggtgcccgcgtgacc agccctacgtcaggcgtgaagaggctgagtcttatggatcaggtgtcgggggtcgaggcc ttcctgcaggccagccagcccccagacccacaccggggtgccaaggtcatccgtgcagac ccgcaggggggccgccgccgccacagctcggagaccttctcctcgaccacaaccgtcacc cccgtgtccccatccttcgcccacaaccctaagcgccacaactcggcctcggtggaaaac gtgtctctcaggaaaggcagcgagggcagcggcggcgtcctcggcgggggcccaggaggc ggcgaagaggcacccatgtccccccgacagctgcagccgtcacttccggtgccctctctc ccgccgcaggcccgcccacgggccccagctccgccagggggcttggtcggctgccctggg ggcagtggttctccaatgcgcagggagacctctgccggcttccagaatggtctcaactac attgccatcgacgtgagggacgagccggggctgacccagccgcagccgcagccaggagac aagagctcctgggggcggacccgtagccttgggggtctcatcagcgctgtgggcagtggc agcagcggggtgtgtggggggccgggccctggcgccctgccctctgccaacacctatgcc agcattgacttcttgtcccatcacttgaaggaggccacgattgtgaaagagtga

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