Lemur catta (Ring-tailed lemur): 123650840
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Entry
123650840 CDS
T08326
Symbol
ALOX12
Name
(RefSeq) polyunsaturated fatty acid lipoxygenase ALOX12 isoform X1
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
lcat
Lemur catta (Ring-tailed lemur)
Pathway
lcat00590
Arachidonic acid metabolism
lcat01100
Metabolic pathways
lcat01523
Antifolate resistance
lcat04726
Serotonergic synapse
lcat04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
lcat00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
123650840 (ALOX12)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
123650840 (ALOX12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
123650840 (ALOX12)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
123650840 (ALOX12)
Enzymes [BR:
lcat01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
123650840 (ALOX12)
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Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
123650840
NCBI-ProteinID:
XP_045425964
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Position
15:9654494..9666594
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AA seq
701 aa
AA seq
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MGRYRIRVATGAWLFSGSHNRVQLWLVGARGEAELELQLRPVRGEEEEFDLDVPEDLGPL
QFVKLRKHHSLVDDAWFCDRITVQRPRACAEEAFPCYRWVRGEGVLSLPEGTARLAGDNA
LDVFQKHREKELKERQHIYCWATWKEGLPLTIAADCEDDLPPNMRFHEEKRRDFEWTLKA
GALEMVLKRVYTLLSSWNHLEDFDQIFWGQKSTLAEKVHQRWQDDELFGYQFLNGANPML
LRRSTSLPSRLVLPSGTEELRAQLEKELQNGSLFEADFILLDGIPANVIRGEQQYLAAPL
VMLKMEPSGKLLPLVIQIQPPNPSSQSPTLFLPSDPPLAWLLAKSWVRNSDFQLHQLQYH
LLNTHLVAEVIAVATMRCLPGLHPVFKLLIPHIRYTMEINTRARTRLISDGGIFDKAVST
GGGGHVQLLRRAMAQLTYCSLCPPDDLADRGLLGIPSAYYAHDASRLWKITARFLPRYNR
SSWADATERGAEVRGWSLLLSESSAPSPLGRYVEGIVHLFYQKDDVVRGDPELQAWCREI
TEVGLRQAQDRGFPISFQSRAQLCHFLTMCVFICTAQHGAINQGQLDWYAWVPNAPCTMR
MPPPTTKEDVTMATVMGSLPDIRQACLQMTITWHLGRRQPDMVPLGHHREKYFSGPKPKA
VLKQFQTDLENLEKEIKARNEQLDLPYEYLKPSRIENSITI
NT seq
2106 nt
NT seq
+upstream
nt +downstream
nt
atgggccgctaccgcatccgcgtggccaccggggcctggctcttctccgggtcgcacaac
cgcgtgcagctgtggctggtcggggcgcgcggggaggcggagctggagctgcagctgcgg
ccggtgcggggagaggaggaggaatttgatcttgacgttcccgaggacttgggacccctg
cagttcgtgaagttgcgcaaacaccactcgctggtggacgacgcgtggttctgcgaccgc
atcacggtgcagcgacccagagcctgcgcggaggaggccttcccgtgctaccgctgggtg
cggggcgagggcgtcctgagcctgcccgagggcaccgcccgcctggcaggagacaatgcc
ttggatgtgttccagaagcatcgagagaaggaactaaaggaaagacaacacatctactgc
tgggccacctggaaggaagggttacccctgaccatagctgcagactgtgaggatgaccta
cctccaaatatgagattccatgaggagaagaggcgggactttgaatggacactgaaggca
ggggccctggagatggtcctcaaacgtgtttacaccctcctgagctcctggaaccaccta
gaagactttgatcagatcttctggggccagaagagtaccctggctgagaaggttcaccag
cgctggcaggacgatgagctttttggctaccagtttctcaatggcgccaaccccatgctg
ttgagacgctccacctctctgccctccaggctagtgctgccctcagggacagaggaactt
cgggcccagctggagaaagaactccagaacggttccctgtttgaggctgacttcatcctg
ctggatggaatcccagccaacgtgatccgaggagagcagcagtacctggctgcccccctc
gtcatgctgaagatggagcccagtgggaagctgctgcccttggtcatccagattcagcct
cccaaccctagctcccaaagcccaacactgttcctgccctcagatcccccgcttgcctgg
ctcctggcaaagtcctgggtccgaaattcagatttccaactgcaccagctccagtatcat
ttactgaacactcatctggtggctgaagtcatcgctgtcgccaccatgaggtgcctccca
ggactgcaccctgtcttcaagctcctgatcccccatatccgctacaccatggaaattaat
acccgggcgcggacccgactcatttcagatggaggaatatttgataaggcagtgagcaca
ggtggagggggccacgtgcagctgctccgtcgggcaatggctcagctgacctactgctcc
ctctgtcctcctgacgacctggctgaccggggcctgctgggaatcccaagtgcttactat
gcccacgatgcttcacggctctggaagatcactgcccggttcctccccagatacaataga
agcagctgggcagatgccacagagagaggagcagaggtcagaggctggagccttctactc
tcagagagctcagctccttctcctctgggcaggtacgtggaggggatcgtccacctcttc
taccaaaaagatgatgtcgtgaggggggaccctgagctgcaggcctggtgtcgggagatc
acagaggtggggctgcgccaggcccaagaccgaggtttccctatctccttccagtcccgg
gctcaactctgccatttccttaccatgtgtgtcttcatatgcactgcccagcatggggcc
atcaaccagggccagctggactggtatgcctgggtccctaatgccccatgcacaatgcgg
atgcccccacccaccaccaaggaagatgtgacaatggccacagtgatggggtcactaccc
gatatccggcaggcctgtcttcaaatgaccatcacatggcacctgggtcgccgccagcca
gacatggtacctctggggcatcacagagaaaaatatttctcaggccccaagcccaaagct
gtgctaaagcaattccaaacagatttggaaaacctggaaaaggagattaaagcccggaat
gagcaacttgacctgccttatgaatacctgaagcccagccgcatagagaacagtatcact
atctga
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