Latimeria chalumnae (coelacanth): 102356548
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Entry
102356548 CDS
T02913
Symbol
HSD17B4
Name
(RefSeq) hydroxysteroid 17-beta dehydrogenase 4
KO
K12405
(3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.-
4.2.1.107
4.2.1.119
]
Organism
lcm
Latimeria chalumnae (coelacanth)
Pathway
lcm00120
Primary bile acid biosynthesis
lcm01040
Biosynthesis of unsaturated fatty acids
lcm01100
Metabolic pathways
lcm01212
Fatty acid metabolism
lcm04146
Peroxisome
Module
lcm_M00861
beta-Oxidation, peroxisome, VLCFA
lcm_M00862
beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA
Brite
KEGG Orthology (KO) [BR:
lcm00001
]
09100 Metabolism
09103 Lipid metabolism
00120 Primary bile acid biosynthesis
102356548 (HSD17B4)
01040 Biosynthesis of unsaturated fatty acids
102356548 (HSD17B4)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
102356548 (HSD17B4)
Enzymes [BR:
lcm01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.107 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase
102356548 (HSD17B4)
4.2.1.119 enoyl-CoA hydratase 2
102356548 (HSD17B4)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
MFE-2_hydrat-2_N
adh_short
MaoC_dehydratas
adh_short_C2
SCP2
KR
Alkyl_sulf_C
FAS1_DH_region
Epimerase
Motif
Other DBs
NCBI-GeneID:
102356548
NCBI-ProteinID:
XP_006010793
Ensembl:
ENSLACG00000003466
UniProt:
H3A2L8
LinkDB
All DBs
Position
Un
AA seq
740 aa
AA seq
DB search
MSAAPLRFDGRVVLVTGAGGGLGREYALAFAERGASVIVNDLGVSIKGEGKSSSAADKVV
EEIRAKGGKAVANYDSVEDGDKLVQTALNEFGRIDVLINNAGILRDRSFARTSDLDWDLI
HRIHLRGSFLVTRAAWNHMKNQKFGRIIMTSSAAGIYGNFGQANYSAAKLGLLGLSNTLA
IEGKKYNIHSNTIAPTAGSRLTQTVMPQDLLDALKAEYVAPLVLWLCHESCQENGSLFEV
GAGWIGKLRWERTLGATVRQKNHMMTPEAVQDAWNQICDFENASKPQSVQGSIQTLHEVL
SKVDTEEAISSNPTSAAAMENSTGIDPSQAVGQKLPPMVYSYTTLQPILYALGVGMSTSD
PDHLKFLFEGNEEFCCLPTFGVIPPQAAIMDGALASVPGLNMDLTRLLHGEQYMDLYKPL
PSSGKLTSQATVADVLDKGSGAVVLLDVFTYNGEDLLCFNQFSLFIVGAGGFGGKRRSDK
VKVTVNPPNRPPDAVMTDGTSVNQAALYRLSGDWNPLHIDPSFAALGGFKKPILHGLCSF
GFAARHVLKYYANNDVSKFKSIKTRFVKPIIPGQTLQTEMWKEGSRIHFQTKIKETGEVS
LAGAYVDLVETSDKSVVKESIVAEGLQSDLVFAEIGRRIKDVGKEMVKKVNAVFQWDIKK
DGKTRVQWTIDLKNGSGDVYKGAARGQADTTFTLSDEDFMEVVLGKLNPQKAFFAGKLKV
KGNIMLSQKLEMILKDYAKL
NT seq
2223 nt
NT seq
+upstream
nt +downstream
nt
atgtcggctgcgccgctcaggtttgacgggcgggtggtcctggtgacgggcgctggagga
ggattaggtagagaatatgccttggcctttgcagaaagaggtgcttctgtgattgtgaat
gatcttggagtcagcatcaaaggtgaagggaaaagttcgtcggctgctgataaagttgtg
gaagaaataagggcgaaggggggcaaagctgttgctaactatgattctgtggaagatgga
gacaagcttgttcagacagcgcttaacgaatttggaagaatagatgtactaataaataat
gctgggatcttaagagaccgttctttcgccagaacaagtgacttggactgggatctaatt
cataggattcatctgaggggatcattcctggtgacaagagccgcatggaaccatatgaag
aatcagaagtttggcagaataatcatgacctcatcagctgctgggatatatggcaacttt
gggcaggcaaactacagtgctgcaaagttgggtcttttgggcctttcaaatacgcttgcc
attgaaggcaaaaaatataacatccacagtaacaccatagcaccgacagcaggatcccga
ttgactcaaactgtcatgcctcaggatcttttggatgctcttaaagctgaatacgtggct
cccctggtcctttggctgtgccatgagtcttgtcaagagaatggcagcttgtttgaggtt
ggagctggctggattggaaaattacgttgggagcgaaccctgggagcaactgtgaggcag
aagaaccacatgatgacaccagaggctgtgcaagatgcctggaatcagatctgtgacttt
gagaatgccagcaagccccagagtgtccaagggtcaatacaaactctacatgaagtattg
tccaaagtagatacagaagaagcaatctccagtaatccaactagtgctgcagcaatggag
aatagcacaggcattgaccctagccaagctgttggtcagaagttgcctcctatggtatac
agttacactaccctgcaacctatattgtatgcactgggagttggcatgtcgaccagtgac
ccagaccacctgaagttcctctttgaaggaaacgaggaattctgctgtctgccaacgttt
ggagttattcctccccaggctgcaataatggatggtgctttagcctctgttcctgggctt
aatatggatcttacaaggctgctgcatggtgaacagtatatggatctgtataagccacta
ccatcctcagggaagttaacctcccaggctacagttgcagatgttctcgacaaaggctct
ggagcggttgtgcttttagatgttttcacttacaatggggaagatctgctctgttttaat
cagttctcattgtttattgtgggagctggaggatttggtggaaagcggagatcagataaa
gtaaaggtcactgtgaacccacctaatagaccacctgatgcggtaatgactgatggtaca
agtgtgaatcaggctgcattgtatcggctcagcggggattggaatcctttacatattgac
cccagcttcgcagctttgggaggttttaaaaagcccattttgcatggattgtgttcattt
ggatttgctgccagacacgtcttgaagtattatgcaaacaatgatgtgtccaaattcaag
tcaatcaagaccaggtttgtgaaacccattattcctggccagaccctacaaactgaaatg
tggaaagaaggcagcagaatccattttcagactaagatcaaagagactggtgaagtttcc
cttgcaggcgcatatgtggatctcgtcgaaacttcagataaatctgtagtcaaagagtcc
attgtggctgaagggctccagagtgaccttgtgtttgcagagattggccggcggattaaa
gatgtgggaaaagagatggtaaaaaaggtgaatgcggtcttccagtgggacataaaaaaa
gatggaaagaccagagtgcagtggacaatcgacctgaaaaatgggtctggagatgtgtac
aaaggggctgcacggggccaagccgacacaacctttaccctctccgatgaagactttatg
gaagtggtcctgggaaagcttaatccgcaaaaagcattctttgctggtaagctgaaggta
aaaggtaatattatgctcagtcagaagctggagatgatcctgaaagactatgcaaaactg
tga
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