KEGG   Latimeria chalumnae (coelacanth): 102356941
Entry
102356941         CDS       T02913                                 
Symbol
PTK2
Name
(RefSeq) protein tyrosine kinase 2
  KO
K05725  focal adhesion kinase 1 [EC:2.7.10.2]
Organism
lcm  Latimeria chalumnae (coelacanth)
Pathway
lcm04012  ErbB signaling pathway
lcm04148  Efferocytosis
lcm04370  VEGF signaling pathway
lcm04510  Focal adhesion
lcm04810  Regulation of actin cytoskeleton
lcm05100  Bacterial invasion of epithelial cells
Brite
KEGG Orthology (KO) [BR:lcm00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    102356941 (PTK2)
   04370 VEGF signaling pathway
    102356941 (PTK2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    102356941 (PTK2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102356941 (PTK2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    102356941 (PTK2)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    102356941 (PTK2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lcm01001]
    102356941 (PTK2)
   01009 Protein phosphatases and associated proteins [BR:lcm01009]
    102356941 (PTK2)
Enzymes [BR:lcm01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     102356941 (PTK2)
Protein kinases [BR:lcm01001]
 Non-receptor tyrosine kinases
  FAK family
   102356941 (PTK2)
Protein phosphatases and associated proteins [BR:lcm01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     102356941 (PTK2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Focal_AT Pkinase FERM_N_2 FERM_M FERM_C_FAK1 Kinase-like Haspin_kinase FERM_F2 ABC1 GIT1_C
Other DBs
NCBI-GeneID: 102356941
NCBI-ProteinID: XP_014348578
LinkDB
Position
Un
AA seq 1097 aa
MRERRTHTEDEQCENQKVDKFYVILRIYSFTQFGTMEFLGFLNCASNDISRLSYPMEYDR
HLAPSKNMAAAYLDPNLNHAPASGAKSRLSAGMERSPGALERVLKVFHYFESNNEPTTWA
SNIRHGDATDVRGIIQKIVDSHKVKSMSCFGLRLSHLPSEEIYWLHPDMGVSHVREKYEL
NHPPDEWKYELRIRYLPKGFLNEFTEDKPTLNFFYQQVKNDYMLEMADQVDQEVALKLGC
LEIRRFYREMRGNALEKKSNYELLEKDVGLRRFFPKTLVDAVKAKTLRKLIQQTFRQFAN
LNEEESILKFFEILSPVYRFDKECFKCALGSSWVISVELAIGPEEGISYLTDKGSTFSIT
EGERALPSIPKLANNEKQGVRPRTVSVSGVNHCQPKVKKARHFLLPFIFCSHEPSPPKAD
EVSGDETDDYAEIIDEEDTYTMPSKSYGIEEARDYEIQRERIELGRCIGEGQFGDVHQGV
YMSPENPAMAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIME
LCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSTDCV
KLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMYGI
KPFQGVKNNDVIGRIENGERLQMPTNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTIL
EEEKLQQEERLRMEMRRQATVPWDSGGSDEAPPKPSRPGYPSPRSSEGFFPSPQHMGQHN
HYQVSNFPCSHGIPAVSGSVYSGQASILDHHDSWNHIRPQDMLMWSPNMEDSGSLDMRGM
SQMLPTHLMEERLIRQQQETEEDQRWLEKEERLLKPDVRISRGSIDREEVGGLQGPTGSQ
HIYQPVGKPDHVAPPKKPPRPGAPSHLGSLASLNNPVESYNEGVKPWRIQPQEISPPPTA
NLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPVL
PASTHREIEMAQKLLNSDLAELINKMKLAQQYVMTSLQQDYKKQMLTAAHALAVDAKNLL
DVIDQARLKMIGQSRPH
NT seq 3294 nt   +upstreamnt  +downstreamnt
atgagagagaggcgcacacacacagaagatgaacaatgtgaaaaccagaaagtcgataag
ttttacgtaatacttcggatttactctttcacacaatttggaacaatggagtttttgggc
tttttgaactgtgcaagtaatgatatttcaaggctttcctacccgatggaatatgacaga
cacctagcaccgagcaaaaacatggcagcagcttacctcgatcccaacttgaatcacgcg
ccggcttcgggtgccaagtcccgcttgagtgccgggatggagcgttcccccggggccctg
gaacgagtactgaaggtctttcattactttgaaagtaacaatgagccaactacttgggcc
agcaacatccggcatggggacgcaaccgatgtcaggggaattatccagaagatcgtagac
agccataaagtaaagagcatgtcctgcttcggattgcgtctcagccacttgccatcggag
gagatttactggctgcacccagacatgggagtgtcccacgtgagggagaagtacgaactg
aatcacccgccagacgagtggaagtatgagttgagaatccgatatttgccaaaaggattt
ctgaacgagtttaccgaggacaagccaaccttaaattttttctatcagcaggtcaaaaat
gactacatgttagaaatggcagaccaggttgaccaggaggtggcgctaaaactaggctgc
cttgaaattcggagattctacagggagatgagagggaatgcactagaaaagaaatcaaac
tatgaactgctagagaaagatgtgggtttgaggagattcttccccaaaacgttggtggat
gctgtgaaggctaaaacgctgcgtaagctgatccagcagacatttcgacagtttgccaat
ctcaatgaagaagagagtattctgaagttctttgagattctttctccggtttacaggttt
gacaaggagtgcttcaaatgtgcccttggatcgagttgggttatttcagtggagctggcg
attggcccagaggaaggaatcagctaccttacagacaagggatccactttctccatcaca
gaaggcgaacgagcgttgccatcgataccgaagctggccaacaacgaaaagcaaggggtg
cgacctcggacagtctccgtttcaggagtgaatcactgtcagcctaaagttaagaaagcc
cggcactttctccttcctttcatcttctgttcacatgaaccatcaccgcctaaggcagat
gaagttagtggggacgagacagatgattatgcggagatcatagatgaagaggacacctac
accatgccgtccaaaagctatggaatagaagaagccagggactacgagattcagagggag
cggattgagctgggccgttgtattggcgaggggcagtttggagatgtccaccaaggagtt
tacatgagtccggagaacccagccatggctgtggccatcaaaacgtgtaaaaactgcact
tcagacagcgtgagggaaaagttcctgcaagaggccttgacgatgcgacagtttgatcac
ccccacatagtgaagttgatcggagtgattaccgaaaacccagtctggataatcatggaa
ctgtgtacattaggggagctgaggtcatttttgcaagtacgaaaatacagcttggacttg
gcctcactgattctctatgcctaccagctcagcacagcactcgcctacttagaaagcaag
aggtttgtacatagggatattgctgctaggaacgtgctggtgtcctccacagactgtgta
aagctaggggactttggtttgtccagatatatggaagacagcacttactacaaagcttcc
aaagggaaattaccaatcaaatggatggctccagagtcgatcaactttagacgttttacc
tcagctagtgatgtgtggatgtttggtgtgtgtatgtgggagatactaatgtatggtata
aagccatttcaaggagtgaaaaacaacgatgtgattggtcggattgaaaacggcgagcgc
ttgcagatgcctacgaactgcccacctaccctctatagccttatgacaaaatgttgggcc
tatgaccccagcagaaggccaaggttcacggaactgaaagcacagctcagtacaatattg
gaagaagagaagctccagcaagaggagaggttacgaatggaaatgaggcggcaggccaca
gtaccgtgggattcaggaggttcagatgaagctcctccaaagcccagcagacctggttac
ccaagtccgcgctccagtgaaggattttttcccagcccacagcacatgggacagcacaac
cattaccaggtctccaatttcccttgctcccatggaattccagcggtgtctggtagtgtc
tattcgggacaggcctccattctggatcaccatgattcctggaatcatattcgtccgcaa
gatatgctgatgtggtcacccaatatggaggattccgggagtctggatatgcgaggaatg
agccagatgcttccgacacacctaatggaggagcgtttgatacggcaacagcaggagacg
gaggaagaccagcgctggctggagaaagaggaacgactcctgaagcctgacgtgagaatt
tcccgtggcagcattgaccgggaggaggttgggggtcttcaggggccgactggtagccag
cacatatatcagcctgtaggtaaaccagatcatgtagctccaccaaagaaaccccctcgc
cctggagcccccagccacttgggcagcctggccagccttaacaatcctgttgaaagttac
aacgaaggagtgaagccatggaggattcagccccaggaaatcagccctccccctaccgcc
aacttggaccgttccaacgacaaggtgtatgagaacgtgacgggattggtgaaagctgtg
atcgagatgtccagcaagatacagccagcaccgccagaggaatatgtacccatggtgaag
gaggttggtttggctttaaggacgttgctggccaccgtggatgaaaccattcctgtactc
ccagcaagcacacacagagagatcgagatggcacagaagctgttgaactctgacctggcg
gaactgatcaacaagatgaagctggcacagcaatacgtcatgaccagcctgcagcaagac
tacaaaaagcagatgcttacagctgctcacgccttagccgtggatgccaaaaacctgttg
gatgtcattgaccaagccagactgaaaatgattggccagtccaggccccattag

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