Leclercia sp. LSNIH3: C3F35_12380
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Entry
C3F35_12380 CDS
T05316
Symbol
metL
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase II
KO
K12525
bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:
2.7.2.4
1.1.1.3
]
Organism
leh
Leclercia sp. LSNIH3
Pathway
leh00260
Glycine, serine and threonine metabolism
leh00261
Monobactam biosynthesis
leh00270
Cysteine and methionine metabolism
leh00300
Lysine biosynthesis
leh01100
Metabolic pathways
leh01110
Biosynthesis of secondary metabolites
leh01120
Microbial metabolism in diverse environments
leh01230
Biosynthesis of amino acids
Module
leh_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
leh_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
leh_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
leh00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
C3F35_12380 (metL)
00270 Cysteine and methionine metabolism
C3F35_12380 (metL)
00300 Lysine biosynthesis
C3F35_12380 (metL)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
C3F35_12380 (metL)
Enzymes [BR:
leh01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
C3F35_12380 (metL)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
C3F35_12380 (metL)
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GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
HTH_11
Motif
Other DBs
NCBI-ProteinID:
AUY39518
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Position
2560565..2562997
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AA seq
810 aa
AA seq
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MSVIAQAGAKGRQLHKFGGSSLADVKCYLRVAGIMAEYSMPGDMMVVSAAGSTTNQLISW
LKLSQTDRLSAHQVQQALRRYQSELIAGLLPADVADGLISTFIQDLERLAGLLDSGVTDA
VYAEVVGHGEVWSARLMAAVLQQQGLEAAWLDARDFLRAERGAQPQVDEGLSYPLLQQLL
VQHPNKRIVVTGFISRSNAGETVLLGRNGSDYSATQIGALAGVSRVTIWSDVAGVYSADP
RKVKDACLLPLLRLDEASELARLAAPVLHARTLQPVSGSDIDLQLRCSYTPDQGSTRIER
VLASGTGARIVTSHDDICLIEFLVPAGHDFKQTHKEIDLILKRAQVRPLAVGVHTDRHLL
QFCYTAEVADSALKILDEAGLPGELRLRQGLALIAMVGAGVTRNPLHCHRFWQQLKGQPV
EFTWQSEEGISLVAVMRTGPTESLIQGLHQSLFRAEKRIGLMLFGKGNIGSRWLELFARE
QTTLSARTGFEFVLAGVVDSRRSLLNYEGLDASRALAFFNDEAIEQDEESLFLWMRAHPY
DDLVVLDVTASEQLADQYLDFASHGFHVISANKLAGASNTRNYRQIHDAFEKTGRHWLYN
ATVGAGLPVNHTVRDLIESGDSILAISGIFSGTLSWLFLQFDGTVPFTDLVDQAWQQGLT
EPDPRVDLSGKDVMRKLVIVAREAGYDIEPGQVRVESLVPADCEEGSVDHFFENGDALNE
QMLQRLEAAREMGLVLRYVARFDANGKARVGVEAVRPEHPLAALLPCDNVFAIESRWYRD
NPLVIRGPGAGRDVTAGAIQSDINRLAQLL
NT seq
2433 nt
NT seq
+upstream
nt +downstream
nt
atgagtgtgatagcgcaggcaggggcgaagggtcgccagctgcacaagtttggtggtagt
agtcttgctgatgtgaaatgttacctgcgggtcgcggggatcatggcagagtattcgatg
ccgggggacatgatggttgtctccgcggcgggcagcaccaccaaccagttgattagctgg
ctgaagttaagccagaccgatcgtctctctgcgcatcaggttcaacaagcgttacgccgt
taccagagtgagctgatcgccggtttattgccagccgacgtggcagatggcctgattagc
acctttattcaggatctggagcgactggccggtttactcgatagcggcgttactgacgcc
gtttatgctgaagtcgtgggccacggcgaagtctggtctgcccgcctgatggcggccgtc
ctgcaacagcagggtctggaagcggcatggctggacgcgcgtgatttcctgcgtgccgag
cgtggcgctcaaccgcaggttgatgaaggcctctcttatcctctgctccagcagttgctg
gtgcagcatccgaacaaacgtatcgtcgtaaccggctttatcagccgcagcaacgcgggt
gaaaccgtgctgctgggacgtaacggctctgactactccgcaacacagatcggtgccctg
gcgggggtgtctcgcgtcaccatctggagcgacgtagccggtgtttacagcgctgacccg
cgtaaggttaaagatgcgtgcctgctgccgctgctgcgtctcgacgaagccagcgagctg
gcccgtctggcggccccggtactgcacgcccgtactctgcagccggtgtctggcagcgat
atcgacctgcaactgcgctgcagctatacgccggatcaaggctcaacccgtatcgagcgc
gtcctggcctccggcacaggggcgcgtatcgttaccagccatgacgacatctgcctgatc
gaattcctcgttcctgccggacatgatttcaaacagacgcataaagagattgacctgatc
ctgaagcgcgcccaggtacgcccgctcgccgtgggtgtgcacactgaccggcacctgctg
cagttctgctataccgcagaagtggccgacagcgcgctgaaaattcttgatgaagcgggc
ctgccgggcgagcttcgtctgcgtcagggtctggcgctgattgcgatggtaggggcgggc
gtcacccgtaacccgctgcactgccaccgcttctggcagcagttgaagggccagccggtg
gagtttacctggcagtcggaagaggggatcagcctggtggcggtcatgcgtaccgggcca
accgaaagcctgatccaggggctgcaccagtcgctgttccgtgctgaaaaacgtatcggt
ctgatgctgtttgggaaaggcaacattggttcccgctggctggagctgttcgcccgcgaa
cagaccacactttcggcgcgtaccggattcgaatttgtgctggcgggcgtggtggatagc
cgccgcagcctgctcaactatgaagggctggatgcgagtcgcgcactggccttctttaac
gacgaagccatcgagcaggatgaagagtcgctgttcctgtggatgcgcgcccacccgtac
gacgacctggtggtgctggatgtgaccgccagcgagcaactggccgatcagtatcttgat
ttcgccagccatggtttccacgtcatcagcgccaacaaactggcgggggccagcaacacc
cgcaactatcgccagatccacgatgcctttgaaaaaacaggtcgtcactggctgtataac
gccaccgtcggggcgggtctgccggtaaaccataccgtgcgcgatctgatcgaaagcggc
gacagcattctggcgatcagcggtatcttctccggtaccctgtcgtggctgttcctgcaa
tttgatggcaccgtgcctttcaccgacctggtggatcaggcgtggcagcaggggctgacc
gagcctgatccgcgtgtggacctctccggtaaagacgtgatgcgtaagctggtgatcgtg
gcccgtgaagcgggttacgacattgagcctggtcaggttcgcgtggagtcgctggtgccg
gcagactgtgaagagggttctgtcgatcacttcttcgagaatggcgatgcgctgaacgag
cagatgttacagcgcctggaggcggcccgcgaaatgggtctggtactgcgctacgtggcg
cgttttgatgccaatggcaaagcacgcgttggcgtggaggccgttcgcccggaacatccg
ctggcggcgctgttgccgtgcgataacgtcttcgccattgaaagccgctggtatcgtgat
aacccgctggtgatccgtgggccgggtgcaggccgcgacgtgaccgccggggcgatccag
tcggatatcaaccgtctggcgcagctgctgtag
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