KEGG   Leishmania enriettii: 94173715
Entry
94173715          CDS       T10389                                 
Symbol
CUR178_06539
Name
(RefSeq) hypothetical protein
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
lenr  Leishmania enriettii
Pathway
lenr00270  Cysteine and methionine metabolism
lenr00450  Selenocompound metabolism
lenr00670  One carbon pool by folate
lenr01100  Metabolic pathways
lenr01110  Biosynthesis of secondary metabolites
lenr01230  Biosynthesis of amino acids
lenr04980  Cobalamin transport and metabolism
lenr04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:lenr00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    94173715 (CUR178_06539)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    94173715 (CUR178_06539)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    94173715 (CUR178_06539)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    94173715 (CUR178_06539)
   04980 Cobalamin transport and metabolism
    94173715 (CUR178_06539)
Enzymes [BR:lenr01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     94173715 (CUR178_06539)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-GeneID: 94173715
NCBI-ProteinID: XP_067695446
UniProt: A0A836KTL0
LinkDB
Position
7:89554..93303
AA seq 1249 aa
MRGERSPIFEELEELFQQRILLLDGGMGTMLQRYKLEEMDFRGEEFKDVTKDLKGNNDLL
CLTQPAKVRDIHYKYAIAGADVIETNTFNAQAVSQSDYETQHLVRRINLAAARICRDAAE
QASRETGRRIFVAGVLGPLNRTASISPSVERPDYRNITYDEIVTAYTEQATALLDGGVDV
LLIETVFDSLNAKAALFALNTLFDDKGYTRVPMMVSGTITDMSGRTLSGQTVDAFYSSMR
HSNIISIGLNCALGCREIRPHIERLAQISEGYVTCHPNAGLPNAMGGYDELPEDMARDIR
DFAVRGWVNLVGGCCGTTPEHIRAMARAVEGVPPRLKGQQSKTMVISGLETLCFTSHIGF
CNIGERCNLSGSLRFKRLVKEGKWEECLAVARKQVEEGAMVLDVNMDDGLIDGVAAMTRF
LNMVASDPEVARVPVMIDSSKFHVIEAGLKCTQGTPIVNSISLKVGEQEFLRQARLIRRY
GAAVVVMAFDEGGQAADCASKIRICKRAYDMLVADGFPPENIVFDPNVLTICTGMEEHNN
YAVDFMNAAAWIKANLPGVKVSGGISNLSFSFRGFETIRMAMHSAFLKKMIADGSLDMAI
VNAGALPVYTDIEPELLQLVEDAIFNRTPNSSERILEYAERLKAEKAAGGGTEEAKVSKV
DEWRRTPVEERLSHALIKGIVEFIEEDIEEARTCGKYERPLSIIEGPLMNGMGKVGELFG
SGKMFLPQVIKSARVMKKAVAVLVPYMEAEKAALMQSANGKSTSRAKRVLMATVKGDVHD
IGKNIVGVVLGCNSYEVIDLGVMVSCEKILAAAQEHEVDVIGLSGLITPSLDEMVHVAKE
MKKAGFEIPLMVGGATTSKQHTAVKIHPHYHKTVHVLDASKSVVTVSNMLGSNKEEFWEE
VHETYQDIAEDYLASLRDRVYKPLAFCREHALKIDFAAHPPAPRPRKLGTISINDYSLEK
ISDRIDWNPFFAVWQVRGTYPNRGVPKLFNCPTVGAEAKRLFDDAQEMLKDIIATRSFRA
KAVVTLMPVNSVGDDIEVYKDDTRIEKIATFFGLRQQAEKESGEPYLCISDFIAPKGVAP
DYLGSLVVGIFGAGKMSEGYEKDNDGYRSIMVKALADRFAEAFTEEVHRIIRTDLWGYAE
KDTTETTELIKMQYQGIRPAPGYPSQPDHTEMDTMWRIGEVEERTGVRLSESYAMMPAAS
VSALVFAHAQSKYFAVGKIQKDQVKDYAARKGWSIERAERQLGSSLAYA
NT seq 3750 nt   +upstreamnt  +downstreamnt
atgcgcggagaacgcagtcccatattcgaggagctggaggagctcttccagcagcgcatc
ctcctgctggacggtggcatgggcactatgctgcagcgctacaaactcgaagaaatggac
ttccgcggcgaggagttcaaagacgtcacgaaagatctcaagggcaacaacgacctgctc
tgtctcacgcagccggcgaaggtacgggatattcactataagtatgccatcgccggtgct
gacgtcattgagacgaacacgttcaacgcccaggcagtgagtcagtccgactacgagaca
cagcacctcgttcgacgaattaacttggccgccgcgagaatctgccgcgacgcggcagag
caagccagccgcgagacagggcggcgcatctttgtcgccggtgtgttgggcccactgaac
cgaacggcctccatctcgccctctgtcgagcgccccgactaccgcaacatcacgtacgac
gagattgtaaccgcttacacggagcaggcgacggccctgctggacggaggtgttgatgta
ttgctgatagagactgtcttcgactccctcaacgccaaggcggccctctttgccctgaac
acactctttgatgacaagggttatacacgcgttccgatgatggtgagtggtaccattaca
gacatgtctggtcgaaccctcagtggccagacagtggacgctttctactcgtcgatgcgg
cacagcaacatcatatcgattggcctcaactgtgccctggggtgccgagaaatacgcccg
catatcgagcgccttgcgcagattagtgagggctacgtgacgtgccaccccaacgcaggg
ctgccgaacgcaatgggtggatacgacgagctaccagaggacatggcccgtgacatccgc
gactttgccgttagagggtgggtcaatctcgtcggtggctgctgcggcaccaccccggag
cacattcgcgctatggccagggcagtggagggcgtcccgccgcgtctgaaggggcagcaa
agcaagacaatggtcatcagcgggctcgagacgctgtgcttcaccagccacatcggcttc
tgcaacatcggcgagcgctgcaaccttagcggctcgcttagattcaagcgcctcgtcaaa
gaagggaagtgggaggagtgcctcgcggtggcccgcaaacaagtcgaggagggagcgatg
gtgctggacgtcaacatggacgacggcctcatcgacggggtggctgccatgacgcgcttc
ctgaacatggtcgcctccgacccggaggtggcgcgggtgccggtaatgatcgactcgtcc
aagttccacgtcatcgaagcgggcctgaagtgcactcagggcacgccgatcgtgaactcg
atctcgctcaaggtgggcgagcaggagttcctgcgccaggcgcgtttgatacggcgttat
ggcgccgccgtggtggtgatggcttttgatgaaggcgggcaggcggcggattgtgccagc
aagatccgcatctgcaagcgcgcgtacgacatgcttgtggcagacggcttccccccggag
aacatcgtcttcgacccgaacgtgctgacaatctgcaccggcatggaggagcacaacaac
tacgccgtggactttatgaatgctgccgcttggatcaaagcaaatctgcccggcgtcaag
gtgagcggcggcatctcaaacctcagcttttccttccgcggcttcgagaccattcgcatg
gccatgcactcagccttcttgaagaaaatgatcgctgacggaagcctcgacatggcgatc
gtgaacgcgggggccttgccggtatataccgatatcgagccggagctgctgcagctggtc
gaagacgccatcttcaaccgcacccccaactcctcggagcgcattcttgagtacgcagag
cggctcaaggcggagaaggcagccggcggtggcaccgaagaggcgaaggtgtccaaggta
gacgagtggcgccgcaccccagtggaagagcgtctctcacacgccttgatcaaaggcatc
gtcgagttcatcgaggaagacatcgaggaagcgcgaacctgtggcaagtacgagcggccg
ctgtccatcatcgagggtccgttgatgaatggcatgggaaaggtgggcgagctgtttggc
agtggcaagatgtttctgccccaggtgatcaagtcggcacgtgtcatgaagaaagcggtg
gcggtgctggtgccgtacatggaggcggagaaggcggcccttatgcagagcgccaacggc
aagtcgacgtctcgggcgaagcgggtgctcatggcgacagtgaagggcgacgtgcacgac
atcggcaagaacattgttggggttgtcctgggctgcaacagctacgaggtgatcgacctt
ggtgtgatggtctcttgcgagaagatcttggcggctgcacaggagcacgaggtcgatgtc
atcgggctctccggcctcatcacgccttcactggacgagatggtgcacgtggcaaaggag
atgaagaaagcgggcttcgaaatcccgctgatggtgggtggtgcaacgacgtcgaagcag
cacacggctgtgaagattcatccgcattaccacaagacagtgcatgtgctggacgccagc
aagtccgtggttacagtgtctaacatgctcgggagcaacaaggaggagttctgggaggag
gtgcacgagacctaccaagatattgcggaggactacctggcgagcctgagggatcgtgtc
tacaagcctctggccttctgccgtgagcacgcgctaaagatcgactttgccgcccaccca
ccggctccgcggccgaggaagctcggcaccatcagcatcaacgactactcgcttgagaag
atatccgaccgcatcgactggaatccttttttcgcagtgtggcaggtgcgcggcacgtac
cccaaccgtggcgtccccaagctgttcaactgccccaccgtcggcgcggaggcgaagcgg
ctcttcgacgacgcgcaggagatgctcaaggacatcatcgccacccgaagcttccgcgcc
aaggccgttgtcacgctgatgcccgtgaatagcgtcggtgacgacatagaggtgtacaag
gatgacacacgtatcgagaagatcgcaacctttttcggtctgcgtcaacaagcggagaag
gagtcgggcgagccgtacctatgcatctcggacttcatcgccccgaaaggggtggcacca
gattacctcggcagccttgttgtcggcatctttggcgcgggcaagatgagcgaggggtat
gagaaggacaacgatggctaccgctctatcatggtcaaggctctggcagaccgcttcgct
gaggcgttcacagaagaggtgcaccgcatcattcgaacggacttgtggggctacgcggag
aaggatacgaccgagacgaccgaactgatcaagatgcagtaccaaggtattcgacccgcc
cccgggtacccttcacagccggaccacacggagatggacacgatgtggcgcatcggcgag
gtagaggagcgcacgggggtgaggctgtctgagtcgtacgcgatgatgccggcggcatcg
gtaagcgcacttgtcttcgcgcatgcgcagtcaaagtactttgcagtgggaaagatccag
aaggatcaggtaaaagactacgccgcgcgtaaggggtggagtatagagcgggctgagagg
cagcttggctcctccctggcctatgcttga

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