KEGG   PATHWAY: leri00531
Entry
leri00531                   Pathway                                
Name
Glycosaminoglycan degradation - Leucoraja erinacea (little skate)
Class
Metabolism; Glycan biosynthesis and metabolism
Pathway map
leri00531  Glycosaminoglycan degradation
leri00531

Module
leri_M00076  Dermatan sulfate degradation [PATH:leri00531]
leri_M00077  Chondroitin sulfate degradation [PATH:leri00531]
leri_M00078  Heparan sulfate degradation [PATH:leri00531]
leri_M00079  Keratan sulfate degradation [PATH:leri00531]
Other DBs
GO: 0006027
Organism
Leucoraja erinacea (little skate) [GN:leri]
Gene
129708906  hyaluronidase PH-20-like [KO:K01197] [EC:3.2.1.35]
129706190  hyal6; hyaluronoglucosaminidase 6 [KO:K01197] [EC:3.2.1.35]
129706191  hyaluronidase-5-like [KO:K01197] [EC:3.2.1.35]
129704631  hyaluronidase-like [KO:K01197] [EC:3.2.1.35]
129704633  hyaluronidase-4-like [KO:K01197] [EC:3.2.1.35]
129704639  hyaluronidase-2-like isoform X1 [KO:K01197] [EC:3.2.1.35]
129704758  hyaluronidase-1-like isoform X1 [KO:K01197] [EC:3.2.1.35]
129704759  hyaluronidase-1-like [KO:K01197] [EC:3.2.1.35]
129704917  hyaluronidase-like [KO:K01197] [EC:3.2.1.35]
129710804  gusb; beta-glucuronidase [KO:K01195] [EC:3.2.1.31]
129702287  ids; iduronate 2-sulfatase [KO:K01136] [EC:3.1.6.13]
129704107  idua; alpha-L-iduronidase isoform X1 [KO:K01217] [EC:3.2.1.76]
129694849  arsb; arylsulfatase B [KO:K01135] [EC:3.1.6.12]
129701247  hpse; heparanase [KO:K07964] [EC:3.2.1.166]
129704134  hpse2; inactive heparanase-2 [KO:K07965] [EC:3.2.1.-]
129708196  sgsh; LOW QUALITY PROTEIN: N-sulphoglucosamine sulphohydrolase [KO:K01565] [EC:3.10.1.1]
129701218  LOW QUALITY PROTEIN: heparan-alpha-glucosaminide N-acetyltransferase-like [KO:K10532] [EC:2.3.1.78]
129712936  si:dkey-192p21.6; heparan-alpha-glucosaminide N-acetyltransferase [KO:K10532] [EC:2.3.1.78]
129710049  naglu; alpha-N-acetylglucosaminidase [KO:K01205] [EC:3.2.1.50]
129715073  galns; N-acetylgalactosamine-6-sulfatase [KO:K01132] [EC:3.1.6.4]
129710798  beta-galactosidase-like [KO:K12309] [EC:3.2.1.23]
129713195  gnsb; glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b [KO:K01137] [EC:3.1.6.14]
129706463  gnsa; N-acetylglucosamine-6-sulfatase [KO:K01137] [EC:3.1.6.14]
129695306  hexb; beta-hexosaminidase subunit beta isoform X1 [KO:K12373] [EC:3.2.1.52]
Compound
C00426  Dermatan sulfate
C00573  Keratan sulfate
C00634  Chondroitin 4-sulfate
C00925  Heparan sulfate
G00526   
G00711   
G00872  DWA-2
G01391   
G01945   
G01977   
G02632   
G09660   
G10008   
G10505  Hyaluronic acid
G12336   
G13034   
G13035   
G13036   
G13037   
G13038   
G13039   
G13040   
G13041   
G13042   
G13043   
G13073   
G13074   
Reference
PMID:27570
  Authors
Greiling H, Stuhlsatz HW, Cantz M, Gehler J
  Title
Increased urinary excretion of keratan sulfate in fucosidosis.
  Journal
J Clin Chem Clin Biochem 16:329-34 (1978)
DOI:10.1515/cclm.1978.16.6.329
Reference
PMID:3161730
  Authors
Fuchs W, Beck M, Kresse H
  Title
Intralysosomal formation and metabolic fate of N-acetylglucosamine 6-sulfate from keratan sulfate.
  Journal
Eur J Biochem 151:551-6 (1985)
DOI:10.1111/j.1432-1033.1985.tb09138.x
Related
pathway
leri00532  Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
leri00533  Glycosaminoglycan biosynthesis - keratan sulfate
leri00534  Glycosaminoglycan biosynthesis - heparan sulfate / heparin
KO pathway
ko00531   
LinkDB

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