KEGG   Lelliottia sp. WB101: DAI21_03165
Entry
DAI21_03165       CDS       T05398                                 
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
lew  Lelliottia sp. WB101
Pathway
lew00270  Cysteine and methionine metabolism
lew00450  Selenocompound metabolism
lew00670  One carbon pool by folate
lew01100  Metabolic pathways
lew01110  Biosynthesis of secondary metabolites
lew01230  Biosynthesis of amino acids
lew04981  Folate transport and metabolism
Module
lew_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:lew00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    DAI21_03165
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    DAI21_03165
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    DAI21_03165
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    DAI21_03165
   04980 Cobalamin transport and metabolism
    DAI21_03165
Enzymes [BR:lew01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     DAI21_03165
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: AVY96761
LinkDB
Position
complement(665126..668809)
AA seq 1227 aa
MSSKVDQLRAQLNERILVLDGGMGTMIQSYRLSEDDFRGERFADWPCDLKGNNDLLVLSK
PDVIAAIHNAYFEAGADIVETNTFNSTTIAMADYQMESLSAEINFEAARLARACADAWTA
RTPDKPRYVAGVLGPTNRTASISPDVNDPAFRNVTFDQLVEAYRESTKALVEGGCDLIMI
ETVFDTLNAKAAIFAVKEEMEALGVDLPIMVSGTITDASGRTLSGQTTEAFYNSLRHADA
LTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDATTMAAQIREWAE
SGFLNIVGGCCGTTPEHIAAMSNAVAGLPPRPLPTLPVACRLAGLEPLTIADDSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWDVIEKGLKCIQGKGIVNSISMKEGVEPFIHHAKRVRRYGAAV
VVMAFDEVGQADTRERKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELRDAVEDVILNRRDDSTERMLELAEKYRGSKSDESAQVQQAEWRSWDVK
KRLEYSLVKGITEFIELDTEEARQLSARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPYIEASKEKGQTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIIDL
GVMVPADKILKTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVSALLSATQRDDFVAKTRKEYDTVRIQHGRKKPR
TPPVTLAAARENDLAFDWASYTPPVAHRLGVQAVTANIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGEEAQRLFKDANDLLDQLSAEKSLNPRGVVGLFPANRVGDDIEIYRDETRT
NVLAVSRHLRQQTEKVGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALAEAYEAQH
DDYNKIMVKAIADRLAEAFAEYLHERVRKVHWGYAANENLSNEELIRENYQGIRPAPGYP
ACPEHTEKGTIWQLLDVETHTGMKLTESYAMWPGASVSGWYFSHPDSKYYAVAQIQRDQV
EDYALRKGMSVSEVERWLAPNLGYDAD
NT seq 3684 nt   +upstreamnt  +downstreamnt
gtgagcagcaaagtagatcaactgcgtgcgcagttaaatgaacgaattctggtgctggac
ggcggcatgggcaccatgatccagagctatcgtctgagtgaagacgattttcgcggcgag
cgtttcgccgactggccttgcgacctgaaaggcaataatgacctgctggtgctgagtaaa
ccggatgtcatcgcggccatccataacgcctattttgaggcgggcgcggacatcgtcgaa
accaataccttcaactcgacaaccatcgccatggcggattaccagatggaatccctgtcg
gcagaaatcaattttgaggccgccaggctggcgcgcgcctgcgctgatgcatggacggcc
cgcacgcccgacaaaccgcgctacgtcgccggggtgcttggccccaccaaccgtaccgcc
tctatttcaccggacgtgaacgatccggccttccgtaacgtgacctttgatcagctggtc
gaggcctatcgtgaatccaccaaagcgctggtggaagggggctgcgatctgatcatgatc
gaaacggtgttcgacactctcaacgcgaaagctgcgatctttgcggtgaaggaagagatg
gaagcgctgggcgtcgatctgccgattatggtctcgggcaccattacggatgcctccggg
cgcaccctttccggtcagacgacggaagcgttttacaactccctgcgccacgcggatgcc
ctcacatttggcctcaactgcgccctcggcccggatgaactgcgccagtacgtgcaggaa
ctctcccgcatcgccgagtgctacgtcacggcgcacccgaacgccggcctgccaaatgcc
tttggcgaatacgatctcgatgcaacgacgatggccgcgcaaattcgggagtgggcagag
tcaggtttcctgaacatcgtcggcggctgctgcggcaccacgccggaacatatcgctgcc
atgagcaatgccgtcgcaggcttgccgccgcgcccgttaccgacgctgccggtggcttgt
cgtctggcaggccttgagccactgaccatcgccgatgacagcctgtttgtgaatgtcggt
gaacgtactaacgtcaccggttccgctaagttcaagcggttaatcaaagaagaaaaatac
agcgaagcgctggacgttgcccgccagcaggtggaaagcggcgcgcagatcatcgatatc
aacatggatgaagggatgctcgacgccgaagcggcgatggtgcgtttcctgaatctgatt
gccggtgagccggacattgcccgcgtgccgatcatgattgactcctcaaagtgggacgtc
atcgaaaaagggctgaagtgcattcagggcaaaggcatcgtcaactctatctcgatgaaa
gagggggtggagccgtttattcatcacgcaaaacgggtgcgccgctatggcgcggccgtg
gtggtgatggcgtttgacgaagtcggccaggccgatacccgcgaacgcaagattgagatt
tgccgccgcgcgtacaagatcctgacggaagaggtcggtttcccgccagaagacatcatt
ttcgaccccaatatctttgccgtcgcgacgggtatcgaagagcataacaactacgcccag
gactttatcggcgcctgcgaggatatcaaacgcgagctgccgcatgcgctgatctccggc
ggtgtctccaacgtttcattctcgttccgcggtaacgatccggttcgtgaagccattcac
gccgtgttcctctactacgccatccgtaacggcatggacatggggatcgtcaacgccgga
cagctggcaatttatgacgacctgcccgccgagctgcgcgacgccgtggaagacgtgatc
ctcaaccgccgcgacgactccactgaacggatgctggagctggcggagaaatatcgcggc
agtaaaagcgacgaaagcgcccaggttcagcaggccgagtggcgctcgtgggacgtgaaa
aagcgtctggaatactcgctggtcaaaggcattactgaatttatcgagctggataccgaa
gaggcccgccagctctccgctcgcccgattgaggtgatcgaagggccgctgatggacggg
atgaacgtggtcggcgacctgtttggcgagggcaaaatgttcctgccgcaggtggtcaaa
tccgcgcgcgttatgaaacaggcggtggcctatctcgaaccctacattgaggccagcaaa
gaaaaagggcagaccaacggcaagatggtgatcgccaccgtcaaaggcgatgtccacgat
atcggcaaaaatatcgtcggcgtggtgctgcagtgcaataactacgaaatcatcgacctc
ggtgtgatggttccggcagacaaaattctcaaaaccgcgcgcgaagtgaatgcggatttg
atcggactttccgggcttatcacgccgtcgctggacgaaatggtcaacgtggcgaaggag
atggagcgccagggctttaccattccgctgctgattggcggtgcgacgacctcaaaagcg
cacactgcggtgaaaatcgagcagaactacagcgggccgacggtctacgtacagaacgcc
tcacgcaccgtgggggtggtgtcggccttgctctctgcgacccagcgtgatgattttgtc
gcgaaaacccgcaaagagtacgacaccgttcgtattcagcatggccgcaaaaaaccgcgc
actccgccagtgacgctggccgccgcgcgggaaaacgatctggccttcgactgggcaagt
tacacgccgccggtggcgcatcgcctgggcgtgcaggcggtcacggcgaacatcgaaacc
ctgcgtaattacatcgactggacgccgttcttcatgacctggtcgctggcgggaaaatac
ccgcgcattcttgaagatgaggtcgtcggtgaagaggcgcagcgcctgtttaaagacgcc
aacgatcttctcgaccagctcagcgctgaaaagagcctcaatccgcgcggcgtcgtgggg
ctgttcccggcgaaccgcgtcggggatgacatcgaaatttatcgcgatgaaacccgcact
aacgtgctggcggtgagccgtcatctgcgccagcaaaccgagaaagtcgggtttgccaac
tactgcctggccgatttcgttgcaccaaaactcagcggcaaagcggactacatcggcgcg
ttcgccgttaccggcgggctggaagaggatgctctcgccgaggcctacgaagcgcagcac
gatgactacaacaaaatcatggtgaaagcgattgctgaccgcctggcagaagccttcgct
gaatacctgcatgagcgggtgcgtaaagtccactggggttacgcggcaaatgaaaacctc
agcaacgaggagctgattcgcgagaactaccaggggattcgtccggcaccgggctatccg
gcctgtccggagcacacggaaaagggcaccatctggcagttgctggatgtggaaacccat
acgggcatgaagctcaccgaatcctacgccatgtggccgggcgcgtccgtctcgggctgg
tatttcagccaccctgacagcaaatactacgcggtggcgcaaatccagcgcgaccaggtg
gaagactatgccctgcgcaaagggatgagtgtctcagaagtagagcgctggctggccccg
aatctgggctacgacgctgattaa

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