Leopardus geoffroyi (Geoffroy's cat): 123576400
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Entry
123576400 CDS
T10761
Symbol
PDGFRB
Name
(RefSeq) platelet-derived growth factor receptor beta isoform X1
KO
K05089
platelet-derived growth factor receptor beta [EC:
2.7.10.1
]
Organism
lgf Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf01521
EGFR tyrosine kinase inhibitor resistance
lgf04010
MAPK signaling pathway
lgf04014
Ras signaling pathway
lgf04015
Rap1 signaling pathway
lgf04020
Calcium signaling pathway
lgf04072
Phospholipase D signaling pathway
lgf04151
PI3K-Akt signaling pathway
lgf04510
Focal adhesion
lgf04540
Gap junction
lgf04630
JAK-STAT signaling pathway
lgf04810
Regulation of actin cytoskeleton
lgf05165
Human papillomavirus infection
lgf05200
Pathways in cancer
lgf05206
MicroRNAs in cancer
lgf05214
Glioma
lgf05215
Prostate cancer
lgf05218
Melanoma
lgf05230
Central carbon metabolism in cancer
lgf05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
lgf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
123576400 (PDGFRB)
04014 Ras signaling pathway
123576400 (PDGFRB)
04015 Rap1 signaling pathway
123576400 (PDGFRB)
04630 JAK-STAT signaling pathway
123576400 (PDGFRB)
04020 Calcium signaling pathway
123576400 (PDGFRB)
04072 Phospholipase D signaling pathway
123576400 (PDGFRB)
04151 PI3K-Akt signaling pathway
123576400 (PDGFRB)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
123576400 (PDGFRB)
04540 Gap junction
123576400 (PDGFRB)
09142 Cell motility
04810 Regulation of actin cytoskeleton
123576400 (PDGFRB)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123576400 (PDGFRB)
05206 MicroRNAs in cancer
123576400 (PDGFRB)
05230 Central carbon metabolism in cancer
123576400 (PDGFRB)
05231 Choline metabolism in cancer
123576400 (PDGFRB)
09162 Cancer: specific types
05214 Glioma
123576400 (PDGFRB)
05218 Melanoma
123576400 (PDGFRB)
05215 Prostate cancer
123576400 (PDGFRB)
09172 Infectious disease: viral
05165 Human papillomavirus infection
123576400 (PDGFRB)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123576400 (PDGFRB)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lgf01001
]
123576400 (PDGFRB)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
lgf04090
]
123576400 (PDGFRB)
Enzymes [BR:
lgf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
123576400 (PDGFRB)
Protein kinases [BR:
lgf01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
123576400 (PDGFRB)
CD molecules [BR:
lgf04090
]
Proteins
123576400 (PDGFRB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
ig
Ig_3
I-set
Ig_2
V-set
VEGFR-1-like_Ig-like
VEGFR1-3_N_Ig-like
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
123576400
NCBI-ProteinID:
XP_045293155
LinkDB
All DBs
Position
A1:196584830..196622605
Genome browser
AA seq
1096 aa
AA seq
DB search
MPAPVLKGQVLLLPLLLLLGPQASWGLVITPPGPELVLNISSTFVLTCSGAAPVVWERMS
QKPLQKTAKNQDGTFSSTLTLTNVTGLDTGEYFCTYKNSLGPEPAERKRLYIFVPDPTMG
FLPVFPEDLFIFLTEISEITIPCRVTDPSLVVTLHEKKVDIPLPIPYDHQRGFSGIFEDK
TYVCKTIIGDREVDSEAYYVYSLQVSSINVSVNAVQTVVRQGENITIMCIVTGNEVVNFE
WTYPRMESGRLVEPVTDFLFNVPSHIRSILHIPNAELGDSGTYICNVSESVNDHRDEKSI
NVTVVESGYVQLLGELDAVQFAELHRSRTLQVVFEAYPPPTVMWLKDNRTLGDSSAGEIA
LSTRNVSETRYVSELTLVRVKVAEAGYYTMRAFHEDAEAQISFQLQVNVPVRVLELSENH
PASGEQTVRCRGRGMPQPHLTWSTCSDLKRCPRELPPTPLGNSSEEDSQLETNVTYWPED
QEFEVVSTLRLRRVDQPLSVRCTLHNLLGHDMQEVTVVPHSLPFKVVVISAILALVVLTI
ISLIILIMLWQKKPRYEIRWKVIESVSSDGHEYIYVDPMQLPYDSTWELPRDQLVLGRTL
GSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVN
LLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTFLQRCSDKRRPPSAELYSNALPAGLPL
PSHVSLPGESDGGYMDMSKDESVDYVPMLDMKGGIKYADIESSSYVAPYDNYVPTAPERT
CRATLINESPVLSYTDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFG
LARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPE
LPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERLLGEGY
KKKYQQVDEEFLRSDHPAVLRSQARFPGFNGLRSPLDTSSVLYTAVQPNESDNDYIIPLP
DPKPEIADEGPLEGSPSLASSTLNEVNTSSTISCDSPLEPQEEPEPEPQLEPQVEPEPPL
DSCCPGPRAEAEDSFL
NT seq
3291 nt
NT seq
+upstream
nt +downstream
nt
atgccagctcctgtcctcaaaggccaggtgctgttgctgcccctgctgttgctgctggga
ccacaggcctcctggggcctggtcatcacacctccggggccagagcttgtcctcaatatc
tctagcaccttcgttctgacctgttcgggtgcagctccggtggtgtgggaacggatgtcc
cagaagcccctgcagaaaacggccaagaaccaggatggcaccttctccagcacactgaca
ctgaccaatgtcactgggctagacacgggagaatacttttgcacctacaaaaactccctc
gggccggagcctgctgagcgaaaacggctctacatctttgtgccagatccgactatgggc
tttcttccggtcttccccgaggacctgttcatctttctcacggaaatatctgagatcaca
attccctgccgagtgacggatccgagcctggtggtgacactgcacgagaagaaagtggat
attccactgcccatcccctatgaccaccaacgtggcttctctggtatcttcgaggacaag
acctatgtctgcaaaaccatcatcggggacagggaagtggattctgaagcctactatgtc
tacagtctccaggtgtcgtccatcaatgtctcagtgaatgcagtgcagactgtggtccgc
cagggtgagaacatcaccatcatgtgcattgtgaccggaaatgaggtggtcaactttgaa
tggacatacccacgcatggagagtgggcggctggtggagccagtgactgacttcctcttc
aatgtaccctcccacatacgctccatcctgcacatccctaatgccgagcttggcgattca
gggacctacatctgcaatgtatcggagagtgtgaatgaccatcgagatgaaaagtccatc
aatgtcactgtggttgagagtggctacgtgcagctgctgggagagctggacgccgtacaa
ttcgcggagctgcaccgcagccggactctgcaggtggtgttcgaggcctacccgccgcct
actgtcatgtggctcaaggacaaccgcacgctaggcgactccagcgcaggcgagattgcc
ctgtccacacgcaatgtgtctgagacccggtatgtgtcagaactgacattggtgcgggtg
aaggtggctgaggctggctactacaccatgcgggccttccacgaggatgcagaggcccag
atctccttccagctgcaggtcaatgtgcctgtccgtgtgctggagctgagtgaaaaccat
cctgccagcggggagcagacagtccgctgtcgcggccggggcatgccccagccacacctc
acctggtctacctgcagtgacctcaaaagatgtccgcgcgagctgccacccaccccactg
gggaacagttccgaggaggacagccagctggagactaacgtgacttactggcctgaggat
caggagtttgaggtggtgagcacgctccgcctgcgccgtgtggatcagcctctgtccgtg
cgctgcactctgcacaacctgctgggccacgacatgcaggaggtcaccgtggtgccacat
tctctgcccttcaaggtggtggtgatctcggccatcctggccttggtggtcctcacaatc
atctccctcatcatcctcatcatgctctggcagaagaagccacgttatgagatccgatgg
aaggtgattgaatctgtgagctctgatggccatgagtacatctacgtggaccctatgcag
ctgccctatgactctacctgggagctgccacgggaccagcttgtgcttggacgcaccctc
ggttctggggcctttgggcaggtggtggaggccacagctcacggcctgagccattctcag
gccacgatgaaagtggcggtcaagatgctgaaatccacagcccgcagcagcgagaagcag
gccctcatgtcagagctgaagatcatgagtcaccttgggccccatctgaacgtggtcaac
ttgctgggggcctgcaccaaaggaggacccatctacatcatcacggagtactgccgctac
ggcgacctggtagactaccttcaccgcaacaagcacaccttcctgcaacgctgctcagac
aagcgccgcccgcccagcgccgagctctacagcaacgccctgcccgcggggctccctctg
cccagccacgtgtccctgcctggggagagtgacggcggctacatggacatgagcaaggat
gagtcggtggactacgtgcccatgctggacatgaaaggaggaatcaaatatgcagacatt
gagtcctccagctacgtggccccttatgacaactacgtccccacagctcccgagaggacc
tgtcgggcgactctgatcaacgagtccccggtgcttagctacacagatcttgtgggcttc
agctaccaggtggccaatggcatggagttcctggcctccaagaactgcgtccaccgagat
ctggcagccaggaacgtgctcatctgtgagggcaagctggtcaagatctgtgactttggc
ctggctcgtgacatcatgagggactcgaactatatctccaaaggcagcaccttcctgcct
ctgaagtggatggctcccgagagcatcttcaacagcctctataccaccctgagtgatgtg
tggtccttcgggatcctactctgggagatctttaccctgggtggcaccccttacccagag
ctgcccatgaatgagcagttctataatgccatcaagcggggttaccgaatggcccagcct
gcccatgcctccgatgagatctacgagatcatgcagaagtgctgggaagagaagtttgag
atccggcctcccttctcccagctggtgctgcttctcgagaggctgctgggtgaggggtac
aagaagaagtaccagcaggtggatgaggagtttctgaggagcgaccacccagccgtcctt
cggtcccaagcccgctttcccggcttcaatggactccgatcccccctggacaccagctct
gtgctctacactgctgtgcagcccaacgagagtgacaatgactatatcatccccctgcct
gaccccaagcccgagattgctgatgagggccccctggagggttcccccagccttgccagc
tccaccctgaatgaagtcaacacctcctctaccatctcctgcgacagccccctggaaccc
caagaggagccagagccagagccccagctcgagccccaggtggagccagagccaccactg
gattcatgttgccctgggcctcgggccgaggcggaggacagcttcctgtag
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