Leopardus geoffroyi (Geoffroy's cat): 123581580
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Entry
123581580 CDS
T10761
Symbol
ROCK2
Name
(RefSeq) rho-associated protein kinase 2 isoform X1
KO
K17388
Rho-associated protein kinase 2 [EC:
2.7.11.39
]
Organism
lgf Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf04022
cGMP-PKG signaling pathway
lgf04024
cAMP signaling pathway
lgf04062
Chemokine signaling pathway
lgf04071
Sphingolipid signaling pathway
lgf04270
Vascular smooth muscle contraction
lgf04310
Wnt signaling pathway
lgf04360
Axon guidance
lgf04510
Focal adhesion
lgf04519
Cadherin signaling
lgf04520
Adherens junction
lgf04530
Tight junction
lgf04611
Platelet activation
lgf04670
Leukocyte transendothelial migration
lgf04810
Regulation of actin cytoskeleton
lgf04921
Oxytocin signaling pathway
lgf05132
Salmonella infection
lgf05135
Yersinia infection
lgf05163
Human cytomegalovirus infection
lgf05200
Pathways in cancer
lgf05205
Proteoglycans in cancer
lgf05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
lgf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
123581580 (ROCK2)
04071 Sphingolipid signaling pathway
123581580 (ROCK2)
04024 cAMP signaling pathway
123581580 (ROCK2)
04022 cGMP-PKG signaling pathway
123581580 (ROCK2)
09133 Signaling molecules and interaction
04519 Cadherin signaling
123581580 (ROCK2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
123581580 (ROCK2)
04520 Adherens junction
123581580 (ROCK2)
04530 Tight junction
123581580 (ROCK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
123581580 (ROCK2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
123581580 (ROCK2)
04670 Leukocyte transendothelial migration
123581580 (ROCK2)
04062 Chemokine signaling pathway
123581580 (ROCK2)
09152 Endocrine system
04921 Oxytocin signaling pathway
123581580 (ROCK2)
09153 Circulatory system
04270 Vascular smooth muscle contraction
123581580 (ROCK2)
09158 Development and regeneration
04360 Axon guidance
123581580 (ROCK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123581580 (ROCK2)
05205 Proteoglycans in cancer
123581580 (ROCK2)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
123581580 (ROCK2)
09171 Infectious disease: bacterial
05132 Salmonella infection
123581580 (ROCK2)
05135 Yersinia infection
123581580 (ROCK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
123581580 (ROCK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lgf01001
]
123581580 (ROCK2)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
lgf03036
]
123581580 (ROCK2)
Enzymes [BR:
lgf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
123581580 (ROCK2)
Protein kinases [BR:
lgf01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
123581580 (ROCK2)
Chromosome and associated proteins [BR:
lgf03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
123581580 (ROCK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH_MRCK
PH
C1_1
Pkinase_C
APH
Motif
Other DBs
NCBI-GeneID:
123581580
NCBI-ProteinID:
XP_045303662
LinkDB
All DBs
Position
A3:132133444..132272965
Genome browser
AA seq
1475 aa
AA seq
DB search
MSRPPATGKMPGAPEAVSGDGAGASRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFP
ALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAM
KLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFCAFQDDKYLYMVMEYMPGGDLVNL
MSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMD
ETGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLV
GTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIKQHPFFKNDQWN
WDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENL
LLSDSPSCRENDSVQSRKNEESQEIQKKLYTLEEHLSTEIQAKEELEQKCKSVNTRLEKV
AKELEEEITLRKNVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQL
EDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESTKQIQQLESNNR
DLQDKNCLLETAKLKLEKEFINLQSVLESERRDRTHGSEIINDLQGRLSGLEEDLKNGKI
LLAKVEMEKRQLQERFTDLEKEKNNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNK
IYESIEEAKSEAMKEMEKNLSEERTLKQKVENLLLEAEKRCSILDCDLKQSQQKINELLK
QKDVLNEDIRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMS
LEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLCKELQQK
KQEFEDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQE
LTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDAQEQLSRLKDEEISAAAIKAQF
EKQLLTERTLKTQAVNKLAEIMNRKEPVKRGSDTDVRRKEKENRKLHMELKSEREKLTQQ
MIKYQKELNEMQAQIAEESQIRIELQMALDSKDSDIEQLRSQLQALHIGLDSSSIGSGPG
DAEADDGFPVHITQSRTMESLSFTYQRSSTSLNIATKPSSSHMLLDSDSDSEEESLPYLP
ISSEPDGTESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVLD
IDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYICHKGH
EFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDRKEEIIAPCKVYYDI
STAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRPSRQ
LAPNKPRLLDLAFKDWDWSFDDVDGGDDDDDVFDF
NT seq
4428 nt
NT seq
+upstream
nt +downstream
nt
atgagccggcccccggcgacggggaaaatgcccggcgcccccgaggccgtgtcgggggac
ggggcgggcgcgagccgccagaggaagctggaggcgctgatccgagaccctcgctcgccc
atcaacgtggagagcttgctggatggcttaaattccttggtccttgatttggattttcct
gctttgaggaaaaacaagaatatagataatttcttaaatagatatgagaaaattgtgaaa
aaaatcagaggtctacagatgaaggcagaagactatgatgttgtaaaagtgatcgggaga
ggtgcttttggtgaagtgcagctggttcgtcataaggcatcacagaaggtttatgctatg
aagcttcttagtaagtttgaaatgataaaaagatcagattctgcttttttctgggaagag
agagatattatggcctttgccaacagtccctgggtggttcagctcttttgtgcttttcaa
gatgataagtatctgtacatggtaatggagtacatgcctggtggagatcttgtaaacctt
atgagtaactatgatgtacctgaaaagtgggccaaattttatactgctgaagttgttctt
gctctggatgccatacactccatgggtctcattcacagagatgtaaagcctgacaacatg
ctcttggataaacatggacacctaaagttagcagattttggcacatgtatgaagatggat
gaaacaggcatggtgcattgtgatacagcagttggaacacctgattatatttcacctgag
gttctcaaatcacaagggggtgatggttactatgggcgagaatgtgattggtggtctgtg
ggtgttttcctttttgagatgctggtgggggatactccattttatgcagattcacttgta
ggaacatatagcaaaattatggatcataaaaactcactgtgtttcccagaagatgcagaa
atttctaaacatgcgaagaatctcatctgtgccttcttaacagatagggaggtacgactt
gggagaaatggggtagaagaaatcaaacaacatcctttctttaagaatgatcagtggaat
tgggataacataagagagacggcagctcctgtagtacctgaactcagcagtgacatagac
agcagcaactttgatgacatcgaagatgataaaggagatgtagaaaccttcccaattcct
aaagcttttgtgggaaatcagctgccttttataggatttacctactatagagaaaatttg
ttattaagtgactctccatcttgcagagaaaatgattcagtacagtcaaggaaaaatgaa
gaaagccaagagattcagaaaaaactatacacgttagaagaacaccttagcactgagata
caagccaaagaagaattagagcagaagtgcaaatctgttaatactcgccttgagaaggta
gcaaaggagctagaagaggagattaccttaaggaaaaatgtggaatcagcattaagacaa
ttagaaagagaaaaggcacttcttcagcacaaaaatgcagaatatcagcggaaagctgat
cacgaagcagacaagaaacgaaatttggaaaacgatgttaacagtttaaaggatcaactt
gaagatttgaaaaaaaggaatcagaactctcaaatatccactgagaaagtaaatcaactc
cagagacaactggatgaaaccaatgctttgctgagaacagaatctgatactgcagcccga
ttaagaaaaacccaggcagaaagtacaaaacagattcagcagctggaatctaacaataga
gatcttcaagataaaaattgtctgctggagactgccaagttaaaacttgaaaaggaattt
atcaatcttcagtcagttctagaatctgaaaggagggaccgaacccacggatcagagata
attaatgacttacaaggtagactatctggcctagaagaagacttaaagaatggcaaaatc
ttattagcgaaagtagagatggagaagagacaactacaggagagatttactgatttggaa
aaggaaaagaacaacatggaaatagatatgacataccaactaaaagttatacagcagagc
ttagaacaagaagaagctgagcataaggctacaaaagcacggctggcagataaaaataaa
atttacgaatccattgaagaagcaaaatcagaagccatgaaagaaatggagaaaaacctc
tcagaggaaaggacgttaaagcagaaggtggaaaacctgttgctggaagctgagaagaga
tgctctatattggactgtgacctcaaacagtcacagcagaaaataaatgaactccttaag
cagaaagatgtgctcaatgaagatatcagaaacttgacattaaaaatagagcaagaaact
caaaagcgctgccttacacaaaatgacttgaagatgcaaacacagcaagttaacacacta
aaaatgtcagaaaagcagttaaaacaggagaataatcatctcatggaaatgaaaatgagc
ttggaaaagcagaacgctgaacttcgaaaagaacgtcaagatgcagatgggcaaatgaag
gaactccaagatcagcttgaagcagagcagtacttctcaactctctataaaacacaggtg
agagaacttaaagaggaatgtgaagaaaagacgaaactttgtaaagaattacagcagaag
aaacaggaattcgaggacgaaagggactccttggctgctcaactggagatcaccttgacc
aaagcagattctgagcagctggctcgttcaattgctgaagagcaatattctgatttggaa
aaagagaaaatcatgaaagagcttgagatcaaagagatgatggctagacacaaacaggaa
ctcactgaaaaagatgctacaattgcatctcttgaagaaactaacaggacactaactagt
gatgttgccaatcttgcaaatgagaaagaagaattaaataacaaattaaaagatgcccaa
gaacagctatcacggttgaaagatgaggagataagtgcagccgctattaaagcacaattt
gagaagcaactattaacagagagaacactgaaaactcaagctgtgaacaagttggccgag
atcatgaatcgaaaagaacctgtcaagcgtggtagtgacactgatgtgcggagaaaagag
aaagagaatagaaagctacatatggagcttaaatctgaacgtgaaaaattgacccagcag
atgatcaagtatcagaaagaactgaatgaaatgcaggctcaaatagctgaagagagccag
attcgaattgaactgcagatggccctggacagtaaagatagtgacattgagcagctgcgg
tcacagctccaggccttgcatattggtctggatagttccagtataggcagtggacccggg
gatgctgaggcagatgatggctttccagttcatatcactcagtcacgcactatggaatcc
ttgtcattcacctaccaacgttcctctacttctctcaatattgccactaagccttccagt
tctcatatgcttcttgactctgattctgactcagaagaagaatctttgccttacttacct
atttcatcggaacctgatggtacagaatcaagactagaaggatggctttcattgcctgtg
cgaaacaacactaagaaatttggatgggttaaaaagtatgtgattgtaagcagtaagaag
attcttttctatgacagtgaacaagataaagaacaatctaatccttacatggttttagat
atagacaaattatttcatgtccgaccagttacacaaacagatgtatatagagcagatgct
aaagaaattccaaggatatttcagattctgtatgccaatgaaggagaaagtaagaaggaa
caagaatttcccgtggagcccgtgggagaaaagtcaaattatatttgccataagggacat
gagttcattcctaccctctatcatttcccaaccaactgtgaggcttgtatgaagccttta
tggcatatgttcaaaccgccccctgcattagagtgccgccgctgccacattaaatgtcat
aaagatcacatggacagaaaggaggagattatagcaccttgcaaagtttattatgatatt
tcgacggccaagaacctattgttattggcaaattctacagaagagcagcaaaagtgggtt
agtcggttggtgaaaaagatacctaaaaagcctccagctccagacccttttgcacggtca
tctcctagaacttcaatgaagatacaacaaaaccagtctattagacggccaagtcgacag
cttgccccaaacaaaccaagattgcttgatttggcatttaaagactgggattggtcattt
gatgatgttgatggtggtgatgatgatgacgatgtttttgatttctga
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integrated database retrieval system
