Leopardus geoffroyi (Geoffroy's cat): 123588317
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Entry
123588317 CDS
T10761
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
lgf Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf00061
Fatty acid biosynthesis
lgf00620
Pyruvate metabolism
lgf00640
Propanoate metabolism
lgf01100
Metabolic pathways
lgf04152
AMPK signaling pathway
lgf04910
Insulin signaling pathway
lgf04920
Adipocytokine signaling pathway
lgf04922
Glucagon signaling pathway
lgf04931
Insulin resistance
lgf04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
lgf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
123588317 (ACACB)
00640 Propanoate metabolism
123588317 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
123588317 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
123588317 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
123588317 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
123588317 (ACACB)
04922 Glucagon signaling pathway
123588317 (ACACB)
04920 Adipocytokine signaling pathway
123588317 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
123588317 (ACACB)
04931 Insulin resistance
123588317 (ACACB)
Enzymes [BR:
lgf01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
123588317 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
123588317 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
123588317 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
123588317
NCBI-ProteinID:
XP_045315078
LinkDB
All DBs
Position
D3:18259531..18372421
Genome browser
AA seq
2456 aa
AA seq
DB search
MTLLLFLSCLIFSCLTFSWLKFWGEMTDFKQVTKSTPEGSCSPSQAPFPASDSSGEPPQK
NDNNGPLPETPNRAEPASHRGADDTDQQRTSGPPPRQNPPGDSLSSDDTSPAPQANATGT
ADLKTPDTDGPSSPAKPQGQRARPLSKKDEKQEHIKRQLMTNFILGSFDDNSSDEDPSAG
LFRESPRKGSRASLGTLSLEAALTAGEPENPVPTIRPSMSGLHLVKKGRELKKVDLHRDF
TVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPE
DLKANAEYIKMADQYVPVPGGPNNNNYANVELVVDIAKRIPVQAVWAGWGHASENPKLPE
LLCKHEIAFLGPPSEAMWALGDKIASTIVAQTLQVPTLPWSGSGLMIEWTEDNLQEGKRI
SVPEDIYDQGCVKDVDEGLEVAEKIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQS
EIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIATPA
VFEFMEQCAVRLAKTVGYVSAGTVEYLYGQDGSFHFLELNPRLQVEHPCTEMIADVNLPA
AQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIATRITSENPDEGF
KPSSGTVQELNFRSNKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVMALK
ELSIRGDFRTTVEYLINLLETERFQNNDIDTEWLDHLIAEKVQAEKPDIMLGVVCGALNV
ADVMFRTCMTDFLHSLERGQVLPAASLLNIVDVELIYDGVKYILKVARQSLTMFVLIMNG
CHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRVTIGNKTCVFEKENDPTVLRSPSA
GKLIQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQESGRVKYIKRAGAVLEAGCVVAKLE
LDDPSKVRPAEPFTGELPSQQTLPIIGEKLHQVFHNVLENLTNVMNGYCLPEPIFSTKLK
EWVQKLMTTLRHPSLPLLELQEIMTSVSGRIPAPVEKSVRRVMAQYASNITSVLCQFPSQ
QIATILDCHAATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKSVVLDLLRRYLRVEH
HFQQAHYDKCVINLREQLKPNMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSEEL
TSILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCPEN
LKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVE
FQFMLPSSHPNRMAVPISVTNPDLLRHSTELFMDSGFAPLCQRMGAMVAFRRFEDFTRNF
DEVISCFANVPREIPLFRKACTPLYSEEENKSLREEPIHILNVAIQYADHLDDEELVPIF
RTFVQSKKNILVEYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLEL
SRMRSFDLTAVPCANHKMHLYLGAAKVKEGAEVTDHRFFIRAIIRHSDLITKEASFEYLQ
NEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRSMVMRYGSRL
WKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDPRSGNIMFHSFGN
KQGPQHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALLKLWGSTDKYPKDI
LTYTELVLDPQGQLVEMNRLPGGNEVGMVAFKMRFKTREYPEGRDAIVISNDITFRIGSF
GLGEDLLYLRASEMARAEGIPKIYLAANSGACIGLAEEIKHMFQVAWVDPGDPHKGFKYL
YLTPQDYTRISSLNSVHCKHIEEEGESRYVITDIIGKDRGLGVENLKGSGMIAGESSLAY
EEIVTISMVTCRALGIGAYLVRLGQRVIQVENSHIILTGAGALNKVLGREVYTSNNQLGG
VQIMHHNGVSHVTVPDDFEGVYTILEWLSYMPKDNRSPVPITTPSDPIDREIEFFPSRVP
YDPRWLLVGRPHPTLKGSWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETR
TVEVVVPADPANLDSEAKIIQQAGQVWLPDSAYKTAQAINDFNREGLPLIIFANWRGFSG
GMKDMYDQVLKFGAYIVDSLRQYKQPVLIYIPPHGELRGGSWVVVDSSINPLCIETYADK
ESRASILEPEGTVEIKFRKKDLIKTMRRIDPVYKKLVEQLGVSELSDKDRKDLEGQLKAR
EDLLLPVYHQVAVLFADLHDRAYCMLEKGVISDILEWKTSRAFLYWRLRRLLLEDQVKQE
ILQASSELSHVHIQSMLRRWFVETEGAVKAYLWDNNQMVVKWLEQHWQGGGGLRSTIREN
IKCLKRDSVLKAIRRLVQDNPDVAVDCIVYLSQHISSAERAEVIHLLSTMDSPAST
NT seq
7371 nt
NT seq
+upstream
nt +downstream
nt
atgaccttgcttctttttctatcttgtttgattttctcctgcttgaccttctcctggtta
aaattctggggggaaatgacagacttcaagcaagtcaccaagagcacacccgaagggagc
tgtagcccaagccaagcgccttttccagcctcagacagctcaggggagccgccgcagaaa
aatgataacaacggccctctgccagagactcctaaccgggctgagccagcctcccacaga
ggtgctgacgatactgatcagcaaagaacttccgggccacccccacgccagaatccccca
ggagactccctttcctctgatgacacctccccagcgcctcaagccaacgcaacagggacc
gcggacctgaagaccccagataccgatggcccgtcgtctccagccaagccccagggccag
cgagccagacccctctccaagaaagacgagaagcaggagcacatcaagaggcagctgatg
accaactttatcctgggctccttcgacgacaactcctccgatgaggaccccagtgccggc
ttgttccgagagtctccccggaagggcagccgggccagcctggggactctgtctctggag
gctgctctcactgcaggcgagccggagaaccccgtccccaccataagacccagcatgtcc
ggactccacctggtgaagaagggccgagaactaaagaaggtggacctgcacagagacttt
accgtggcctccccggctgagtttgtcacgcgcttcgggggggatcgggtcattgagaag
gtgctcatcgccaacaacggcatcgccgccgtgaagtgcatgcgctccatccgcaggtgg
gcctatgagatgttccgcaacgagcgggccatccggtttgttgtcatggtgaccccagag
gacctgaaggccaatgcagagtatatcaagatggcagatcagtacgtccctgtcccagga
gggcccaacaacaacaactatgccaacgtggagctggttgtggacattgccaagaggatc
cccgtgcaggcggtgtgggctggctggggccatgcttccgaaaaccccaaactcccggag
ctcctgtgcaagcatgagattgctttcttaggccctcccagtgaggccatgtgggccttg
ggagataagatcgcctccaccattgtggcccagacgctgcaggtcccaacactgccttgg
agtggaagtggtctgatgatagagtggacagaagataatctgcaggaggggaaaagaatc
agtgtcccagaagacatttacgaccagggttgtgtgaaagatgtggatgagggcctagag
gtggcagagaaaattggttttcccttgatgatcaaagcttctgaaggcggtggagggaaa
ggaatccggaaagcagagagtgctgaggacttcccaatccttttcagacaagtgcagagt
gagatcccgggctccccgatctttctcatgaagctggcccagcacgcccggcacctggag
gtccagatcctcgccgaccagtacgggaacgccgtgtctctgttcgggcgtgactgctcc
atccagcggcggcatcagaagatcatcgaggaggcaccggccaccatcgccacaccggct
gtgttcgagttcatggagcagtgtgccgtccgcctggccaagaccgtgggctacgtgagc
gcggggacggtggaatacctctacggccaggatggcagcttccactttctggagctgaat
ccccgcctgcaggtggagcacccgtgcacggaaatgatcgccgacgtcaacctgccggcc
gcccagctccagatcgccatgggggtgccgttgcaccggctgaaggatatccggcttctg
tacggagagtcgccatggggggtgacacccatttcatttgaaactccttctaaccctccg
ctcgcccgaggccatgtcatcgcgaccagaatcaccagcgagaacccagatgaggggttt
aagccaagctccggaacggttcaggaactgaatttccgcagcaacaagaatgtgtggggt
tatttcagcgtggctgctactggcggcttacatgaatttgcggattcccagttcgggcac
tgcttctcctggggagagaaccgggaagaggccatttcgaacatggtgatggctttgaag
gagctgtccatccggggcgacttcaggaccaccgtggagtatctcattaacctgctggag
accgagcgtttccagaacaatgacatcgacacagagtggttggatcacctcatcgctgag
aaagttcaggctgagaagccagatatcatgcttggggtggtgtgtggagccttgaacgtg
gccgatgtgatgttcagaacctgcatgacggatttcttacactcgctggaaaggggccag
gtccttcctgccgcttctctgctgaacatcgtggatgtggaattaatttatgatggtgtt
aagtacattctcaaggtggcccggcaatctctgaccatgttcgtcctcatcatgaacggc
tgtcacatcgagatcgacgcccaccggctgaatgacggcgggttactgctgtcctacaat
ggcaacagctataccacctacatgaaagaagaggttgacagttaccgtgttaccattggc
aacaagacctgtgtgtttgagaaggagaacgatcccacggtcctgaggtccccttcggcc
gggaagctaatacagtacacggtggaggacgggggccacgtcgaggctgggagcagctac
gcggagatggaggtgatgaagatgatcatgaccctgaacgtgcaggaaagcggccgggtg
aagtacatcaagcgtgcgggggccgtgctggaagcaggctgtgtggtggccaagctggaa
ctcgatgacccttccaaagtgcgcccggccgagccattcacaggagagctcccttcccag
caaactctgcccatcatcggagagaaactacaccaggttttccacaacgtcctggaaaac
ctgaccaacgtcatgaatggctactgtctgccagagcctatttttagcacaaagctgaag
gagtgggtgcagaaactcatgacgaccctgcggcacccgtccctgccgctgctggagctg
caggagatcatgaccagcgtgtcgggccgtatccccgcccccgtggagaagtcggtccgc
agggtgatggctcagtatgccagcaacatcacctcggtgctgtgccagttccccagccag
cagatagccactatcctggactgccatgcggccaccctgcagcggaaggctgaccgggag
gtgttcttcatgaacacccagagcatcgtgcagctggtccagaggtaccgcagcgggacc
cgtggctacatgaagtcagtggtgttggatctcctgagaagatatttacgcgtggaacac
catttccaacaagctcactacgacaagtgtgtgatcaacctcagggagcagctgaagcca
aacatgtcccaggtgctggactgcatcttttcccacgcgcaggtggccaagaagaaccag
ctggtgatcatgttgatcgatgagctctgtggcccagacccttccctgtcggaagagctg
acctccatcctcaacgagctcactcagctgagcaaaagcgagcattgcaaagtggccctc
agagcgagacagatcctgatcgcctcccacctcccgtcctacgagctgaggcacaaccag
gtggagtccattttcctgtccgccatcgacatgtatggccaccagttctgcccggaaaac
ctcaagaaattaatactgtcagagacgaccatattcgacgtcctgcccactttcttctac
cacgctaacaaggtcgtttgcatggcgtccctggaggtttacgtgcgaaggggctacatc
gcctatgagttaaacagcttgcagcaccggcagctcccagatggcacctgtgtggtagaa
ttccagttcatgctgccctcctcccacccaaaccggatggccgtgcccatcagtgtcacc
aaccccgacctgctgaggcacagcaccgagctcttcatggacagcggctttgccccactg
tgtcagcggatgggggccatggttgccttcaggagatttgaggacttcacgagaaacttc
gacgaagtcatctcctgctttgccaacgtgcccagggaaatccccctcttcaggaaggcc
tgcactcccttgtactctgaagaagagaacaagagcctcagagaggagccaatccacatc
ctgaatgtggccatccagtacgcggaccacctggacgatgaggagctggtgccgattttc
cggacgtttgtacagtccaagaaaaacatccttgtggaatatggactccgaagaatcaca
ttcctgattgcccaagagaaagaatttccgaagtttttcacattcagagcaagggatgag
tttgcagaagatcgcatttaccgtcacctggagcccgccctggccttccagctggagctc
agccggatgcgcagcttcgatctgaccgccgtgccctgcgccaaccacaagatgcacctg
tacctgggcgccgccaaagtgaaagaaggcgcagaggtgacagaccacagattcttcatc
cgcgccatcatccggcactcggacctcattacgaaggaagcctcctttgagtacctgcag
aacgagggtgagcgtctgctcctggaagccatggatgagctggaggtggcgttcaacaac
accagtgtacgcaccgactgcaaccacatcttcctgaacttcgtgcccaccgtcatcatg
gaccccttcaagatcgaggagtccgtgcgttccatggttatgcgctacggcagccggctg
tggaaactccgcgtactgcaggctgaggtcaagatcaacatccgccagaccaccaccggc
agtgctgttcccatccgcctgttcatcaccaacgagtcgggctactacctggacatcagc
ctctacaaagaagtcaccgaccccagatctggaaacatcatgtttcactcctttggcaac
aaacagggcccccagcacgggatgctgatcaacactccctacgtcaccaaggatctgctt
caggccaagcgattccaggcccagtccctgggcaccacctacgtgtacgacttcccggag
atgttcaggcaggctctccttaaactgtggggctccacggacaagtaccccaaagacatc
ctgacatacaccgagctcgtgctggaccctcagggccagctggtggagatgaaccgcctc
cctggaggaaatgaggtgggcatggtggccttcaagatgaggtttaagacccgagagtat
ccagaagggcgggacgcgatcgtcatcagcaatgacatcaccttccgcattggatccttc
ggcctgggagaagaccttttgtatctgcgtgcgtctgagatggcccgggcagagggtatc
cccaaaatctacctcgcagccaacagcggggcctgtatcggccttgcagaggagatcaag
cacatgttccaggtggcttgggtggacccaggagacccccacaaaggatttaaatacctg
tacctgacgcctcaagactacaccagaatcagctccctaaactctgtccattgtaaacac
atcgaggaagagggagagtccaggtatgtcatcacggatatcatcgggaaggaccgtggc
ctgggcgtggagaacctcaagggctcgggcatgattgcaggggagtcctccctagcttac
gaagagatcgtcaccatcagtatggtgacctgccgagcccttgggatcggggcctacttg
gtgaggctgggccagcgagtgatccaggtggaaaattcgcacatcatcctgacgggagcc
ggcgctctcaacaaggtcctgggcagagaggtttacacctccaacaaccagctgggcggc
gtgcagatcatgcatcacaacggcgtctcccacgtcactgtgccagacgacttcgagggc
gtgtacaccatcctggagtggctgtcctatatgccaaaggataatcgcagtccagtcccc
atcaccacaccctcggaccccattgaccgagaaattgaattcttcccgtccagggttccc
tacgacccccggtggctgcttgtgggacggcctcacccaactctgaagggatcctggcag
agtggattctttgaccacggcagtttcaaggaaatcatggcgccttgggcccagacggtg
gtgacaggaagagcgaggctaggggggatccctgttggagtgatcgccgtggagacgcgg
accgtggaggtggtggtgcctgcagaccctgccaacctggattccgaggccaagataatc
cagcaggcgggccaggtgtggctcccagactcagcctacaagacggcccaggccatcaac
gatttcaaccgagagggattgcccctgataatctttgccaactggagggggttctccggt
ggcatgaaagacatgtacgaccaggtgctaaagtttggagcctacatcgtggacagcctc
aggcagtacaaacagcccgtcctgatctatatcccaccccacggggaactccgggggggc
tcctgggtggtcgtggactcctccatcaaccccctgtgcatagaaacgtacgcagacaag
gagagcagggcgagcattctggagccggagggaacagtggagattaagttccgaaagaaa
gatctgataaagaccatgaggaggatcgacccagtttataagaagctcgtggaacagcta
ggagtgtccgagctctccgataaggaccgcaaggacctggagggccagctgaaggcccgg
gaggacctgctcctgcccgtctaccaccaggtggcggtgctgttcgccgacctccacgac
agggcctactgcatgctggagaagggtgtcatctctgacatcttggagtggaagacctca
cgcgccttcctgtactggcgtctgcgccgcctcctgctggaggaccaggtcaagcaggag
atcctgcaggccagcagtgagctgagccacgtgcacatccagtccatgctgcgtcggtgg
ttcgtggagacggagggggccgtcaaggcctacctgtgggataacaaccagatggtggta
aagtggctggaacagcactggcagggcgggggcggcctgcgttccaccatccgcgagaac
atcaagtgtttgaagcgcgactccgtcctcaaggctatcagacgcctggttcaagacaac
cctgacgtggccgtggactgcatcgtgtacctgagccagcacattagctcagcagagcgg
gccgaagtcattcacctcctgtccaccatggacagcccagcctccacctga
DBGET
integrated database retrieval system
