Leopardus geoffroyi (Geoffroy's cat): 123591276
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Entry
123591276 CDS
T10761
Symbol
CACNA1C
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C isoform X1
KO
K04850
voltage-dependent calcium channel L type alpha-1C
Organism
lgf Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf04010
MAPK signaling pathway
lgf04020
Calcium signaling pathway
lgf04022
cGMP-PKG signaling pathway
lgf04024
cAMP signaling pathway
lgf04260
Cardiac muscle contraction
lgf04261
Adrenergic signaling in cardiomyocytes
lgf04270
Vascular smooth muscle contraction
lgf04713
Circadian entrainment
lgf04720
Long-term potentiation
lgf04723
Retrograde endocannabinoid signaling
lgf04724
Glutamatergic synapse
lgf04725
Cholinergic synapse
lgf04726
Serotonergic synapse
lgf04727
GABAergic synapse
lgf04728
Dopaminergic synapse
lgf04742
Taste transduction
lgf04911
Insulin secretion
lgf04912
GnRH signaling pathway
lgf04921
Oxytocin signaling pathway
lgf04924
Renin secretion
lgf04925
Aldosterone synthesis and secretion
lgf04927
Cortisol synthesis and secretion
lgf04929
GnRH secretion
lgf04930
Type II diabetes mellitus
lgf04934
Cushing syndrome
lgf04935
Growth hormone synthesis, secretion and action
lgf05010
Alzheimer disease
lgf05020
Prion disease
lgf05022
Pathways of neurodegeneration - multiple diseases
lgf05031
Amphetamine addiction
lgf05207
Chemical carcinogenesis - receptor activation
lgf05410
Hypertrophic cardiomyopathy
lgf05412
Arrhythmogenic right ventricular cardiomyopathy
lgf05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
lgf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
123591276 (CACNA1C)
04020 Calcium signaling pathway
123591276 (CACNA1C)
04024 cAMP signaling pathway
123591276 (CACNA1C)
04022 cGMP-PKG signaling pathway
123591276 (CACNA1C)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
123591276 (CACNA1C)
04929 GnRH secretion
123591276 (CACNA1C)
04912 GnRH signaling pathway
123591276 (CACNA1C)
04921 Oxytocin signaling pathway
123591276 (CACNA1C)
04935 Growth hormone synthesis, secretion and action
123591276 (CACNA1C)
04924 Renin secretion
123591276 (CACNA1C)
04925 Aldosterone synthesis and secretion
123591276 (CACNA1C)
04927 Cortisol synthesis and secretion
123591276 (CACNA1C)
09153 Circulatory system
04260 Cardiac muscle contraction
123591276 (CACNA1C)
04261 Adrenergic signaling in cardiomyocytes
123591276 (CACNA1C)
04270 Vascular smooth muscle contraction
123591276 (CACNA1C)
09156 Nervous system
04724 Glutamatergic synapse
123591276 (CACNA1C)
04727 GABAergic synapse
123591276 (CACNA1C)
04725 Cholinergic synapse
123591276 (CACNA1C)
04728 Dopaminergic synapse
123591276 (CACNA1C)
04726 Serotonergic synapse
123591276 (CACNA1C)
04720 Long-term potentiation
123591276 (CACNA1C)
04723 Retrograde endocannabinoid signaling
123591276 (CACNA1C)
09157 Sensory system
04742 Taste transduction
123591276 (CACNA1C)
09159 Environmental adaptation
04713 Circadian entrainment
123591276 (CACNA1C)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
123591276 (CACNA1C)
09164 Neurodegenerative disease
05010 Alzheimer disease
123591276 (CACNA1C)
05020 Prion disease
123591276 (CACNA1C)
05022 Pathways of neurodegeneration - multiple diseases
123591276 (CACNA1C)
09165 Substance dependence
05031 Amphetamine addiction
123591276 (CACNA1C)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
123591276 (CACNA1C)
05412 Arrhythmogenic right ventricular cardiomyopathy
123591276 (CACNA1C)
05414 Dilated cardiomyopathy
123591276 (CACNA1C)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
123591276 (CACNA1C)
04934 Cushing syndrome
123591276 (CACNA1C)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
lgf04040
]
123591276 (CACNA1C)
Ion channels [BR:
lgf04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
123591276 (CACNA1C)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
CAC1F_C
PKD_channel
Motif
Other DBs
NCBI-GeneID:
123591276
NCBI-ProteinID:
XP_045321264
LinkDB
All DBs
Position
B4:complement(34956492..35714270)
Genome browser
AA seq
2225 aa
AA seq
DB search
MVNENTRMYIPEENHQGSNYGSPRAAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
QAKLMGSAGNATISTISSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
TMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGD
FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNRSTPAGLLDQKKGKFAW
FSHSTETHVSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRR
KCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKM
YSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWN
SLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQS
LLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDN
LADAESLTSAQKEEEEEKERKKLARPARTASPEKKQEIMEKPAVEETKEEKIELKSITAD
GESPPTTKINMDDLQPNENEDKSPYPNPENTGEDDEEEPEMPVGPRPRPLSELHLKEKAV
PMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHI
LFYFDIVFTTIFTIEIALKILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNIL
DLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI
VIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWE
NSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIII
IAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKV
WYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIA
FKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVN
PAEHTQCSPFMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVA
LLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLA
CMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTR
DWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLV
SMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQV
VPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPE
IRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTT
QRPLHINKAGNGQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRFPRPAGY
PSAVSTVEGHGPPLSPAVRVQEAAWKLSSKRIHCYDVLGRCHSRESQIAMVCQEEVSQDE
TYDVKISEDTEYCSEPSLISTEMLSYQDDENRQLTPPEEDKRDIRQSPKRGFLRSASLGR
RASFHLECLKRQKNQGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPSTSPRPCATP
PATPGSRGWPPQPIPTLRLEGAESNEKLNSSFPSIHCSSWSGEPTPCGGGGSTIRRARPV
SLTVPGQAGAQGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEM
ENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAEGQEGETCAPTLACRKSEEELQDSRA
HVGSL
NT seq
6678 nt
NT seq
+upstream
nt +downstream
nt
atggtcaatgagaacacgaggatgtacattccagaggaaaaccaccaaggttccaactat
gggagcccgcgcgcagctcacgccaacatgaatgccaatgcggctgcggggctcgccccc
gagcacatcccaacgcccggggcagccttgtcctggcaggcagccatcgacgcagcccgg
caggctaagctgatgggcagcgctggcaatgcaaccatctccaccatcagctccacacag
cggaagaggcagcaatatgggaaacccaagaagcagggcagcacgaccgccacacgcccg
ccccgcgccctgctctgcctgaccctgaagaaccccatcaggagggcgtgcatcagcatc
gtcgaatggaaaccatttgaaataattattttactgactatttttgccaattgtgtggcc
ttagcgatctatattccctttccagaagatgactccaatgccaccaattccaacctggaa
cgagtggaatatctctttctcataatttttactgtggaagcatttttaaaagtaatagcc
tatggacttctctttcaccccaacgcttacctccgcaatggctggaatttactagatttt
ataattgtggttgtagggctttttagtgcaattttagaacaagccaccaaagctgacggg
gcaaatgctctaggagggaaaggagctggatttgatgtgaaggcactgagggcattccgc
gtgctgcgccccttgcggctggtgtctggagtcccaagtctccaagtcgttctgaattcc
attatcaaggccatggtccccctgctgcatattgccctgttagtgctatttgtcatcatc
atctacgctatcattggcctggagctcttcatgggaaagatgcataagacctgctacaac
caggagggcatagcagatgttccagcagaagatgatccttccccttgtgctctggagact
ggccatgggcggcagtgccagaatggcactgtgtgcaagcctggctgggacgggcccaag
cacggcatcaccaactttgacaattttgccttcgccatgttgacagtgttccagtgcatc
accatggagggctggacagatgtgctatactggatgcaggacgctatgggctatgagtta
ccctgggtgtattttgtcagtctggtcatctttggatcctttttcgttctaaatctggtt
ctcggtgtgttgagcggagagttttccaaagagagagagaaggccaaggctcggggagac
ttccagaagctgcgagagaagcagcagctggaagaggacctgaagggctacctggactgg
atcacccaggcagaggacatcgaccctgagaacgaggacgaaggcatggatgaggagaag
ccccgaaacagaagcactccagcgggcttgcttgatcagaagaaagggaagtttgcttgg
tttagtcactccacagaaacccatgtgagcatgcccacaagtgagaccgagtctgtcaac
accgaaaacgtggctggaggtgacatcgagggagagaactgcggggccaggctggcccat
cggatttccaaatcaaagttcagccgctactggcgtcggtggaatcggttctgcagaaga
aagtgtcgtgctgcagtcaagtctaatgtcttctactggcttgtgatcttcctggtgttc
ctcaacacactcaccatcgcctcagaacattacaaccagccccactggctcacagaggtc
caagacacggccaacaaggcactactggcccttttcactgcggagatgctgctaaagatg
tacagcctgggtctgcaggcctactttgtgtccctcttcaaccgctttgactgcttcatc
gtgtgtgggggcattctggagaccatcctggtggagaccaagatcatgtctcccttgggc
atctctgtgctgagatgtgtccggctactgcggatatttaaaatcacaaggtactggaac
tccttaagcaacctggtggcatccttgctgaattctgtgcgctccattgcctccctgctg
ctactcctcttcctcttcatcatcatcttctccctcctggggatgcagctctttggagga
aagttcaactttgatgagatgcagactcggaggagcacatttgataactttcctcagtcc
ctcctcaccgtgtttcagatcctgaccggggaggactggaattcggtgatgtatgatggg
atcatggcttatggcggcccctcttttccagggatgttagtctgtatttacttcatcatc
ctcttcatctgtggaaactatatcctactgaatgtgttcttggccattgctgtggacaac
ctggctgatgctgagagcctcacatctgcccaaaaggaggaggaagaagagaaggagaga
aagaagctggccagaccggccaggactgccagcccagagaagaagcaagagataatggaa
aagccagctgtggaggaaaccaaggaggagaaaattgagctgaaatccattacagctgat
ggagagtccccacccaccaccaagatcaacatggatgacctccagcccaatgaaaatgaa
gataagagtccctaccccaacccagaaaatacaggagaagacgatgaagaggagcctgag
atgcctgtgggcccccgcccacgaccactctctgagctgcaccttaaggaaaaggcagtg
cccatgccagaagccagtgcatttttcatcttcagccccaacaacagatttcgcctccag
tgccaccgcattgtcaatgacacgatcttcaccaacctgatcctcttcttcattctgctc
agcagcatttccctggcagctgaggaccctgtccagcacacctccttcaggaaccatatt
ctgttttattttgacattgttttcactaccattttcaccattgaaattgctctgaagatc
ctaggcaatgcagactatgtcttcactagtatctttacattagaaattatccttaagatg
actgcttatggggctttcctacacaagggctctttctgccggaactacttcaacatctta
gacctgctggtggtcagcgtgtcccttatctcctttggcatccagtccagtgcaattaat
gtggtgaagatcttgagagttctgcgagtcctcaggcccctgagggccatcaacagggcc
aaggggctaaagcacgtggtccagtgcgtgtttgtcgccatccggaccatagggaatatc
gtgattgtcaccacgctgctccagttcatgttcgcctgcatcggggtccagcttttcaag
ggaaagctctacacctgttcagatagttccaagcagaccgaggcggaatgcaagggtaac
tacatcacatacaaggatggggaagttgaccatcccatcatccagcctcgcagctgggaa
aacagcaagtttgactttgacaatgttctggcagccatgatggccctctttaccgtctcc
acctttgaggggtggccagagctgctgtaccgctccatcgactcccacacagaagacaag
ggccccatctacaactaccgtgtggagatctccatctttttcatcatctacatcatcatc
attgccttcttcatgatgaacatcttcgtgggttttgtcatcgtcaccttccaggagcag
ggggagcaggaatacaagaactgtgaactggacaagaaccagcgacagtgtgtggaatat
gccctcaaggcccggcccctgcggaggtacatccccaaaaaccagcaccagtacaaagtg
tggtacgtggtcaactccacctactttgaatacctgatgttcgtcctcatcctgctcaac
accatctgcttggcaatgcagcactatggccagagctgcctattcaaaatcgccatgaac
atcctcaacatgctcttcactggcctcttcactgtggagatgattctgaagctcattgcc
ttcaaacccaagggttactttagtgatccctggaatgtttttgacttcctcatcgtaatt
ggcagcataattgacgtcattctcagtgaaactaatcactatttctgtgatgcatggaat
acatttgacgccttgattgttgtgggtagcattgttgatatagcaatcaccgaggtaaac
ccagctgaacatacccaatgctctccctttatgaacgcagaggagaactcccgcatctcc
atcaccttcttccgcctcttccgggtcatgcgcctagtcaagctgctaagccgtggggag
ggcatccggaccctgctgtggaccttcatcaagtccttccaggctttgccctatgtggcc
cttctgatagtgatgctgttcttcatctacgcagtgatcgggatgcaggtgtttgggaaa
attgccctgaatgacaccacagagatcaaccggaacaacaactttcagaccttcccccaa
gctgtgctccttctcttcaggtgtgccacaggggaggcatggcaagacatcatgctggcc
tgcatgccagggaagaagtgtgcccccgagtcagagcccagcaacagcacggaaggggaa
acgccctgtggcagcagttttgccgtcttctacttcatcagcttctacatgctctgtgcc
ttcctgatcatcaacctctttgtagctgtcatcatggacaactttgactacctgacaaga
gactggtcaatccttggtccccatcatctggatgaatttaaaagaatctgggcagagtat
gatcctgaagctaagggtcgtatcaaacacctagatgtggtgaccctgctccggcggatt
cagcccccactgggttttgggaagctgtgccctcaccgcgtggcttgcaaacgcctggtc
tccatgaacatgcctctgaacagtgatgggactgtcatgttcaatgccaccctatttgcc
ctagttcggacagccctgcggatcaaaacagaagggaacctagaacaagccaatgaggag
ctgcgggccataatcaagaagatctggaagcgtaccagcatgaagctgctagaccaagtg
gtgccccctgcaggtgatgatgaggtcactgttggcaagttttatgctactttcctgatc
caagagtacttccggaaattcaagaagcgcaaagagcagggccttgtgggcaagccttcc
caaaggaacgccctgtccttgcaggctggcttgcgcacgctgcatgacattgggcctgag
atccgacgggccatctctggagatctgacagctgaggaggagctggacaaggccatgaag
gaggctgtgtctgctgcctccgaagatgacatcttcaggagggccggtggcctgttcggc
aaccacgtcagctactaccaaagcgacggccggagcgccttcccccagaccttcaccacc
cagcgcccactgcacatcaacaaggcgggtaacggccaaggcgacaccgagtcgccatcc
cacgagaaactggtggactccaccttcacccccagcagctactcgtccactggctccaac
gccaacatcaacaatgccaacaacactgccctgggccgcttcccccgtcccgctggctac
cccagcgcagtcagcaccgtggagggccatgggccccccttgtctcctgctgtccgggta
caggaggcagcatggaagctcagctccaagaggatacattgctatgatgtgctgggacgg
tgccactcccgggagagccagatagccatggtgtgtcaggaggaggtctctcaggacgag
acctatgacgtgaagataagtgaagacactgagtactgcagcgagcccagcctgatctcc
acagagatgctctcctatcaggatgatgaaaatcggcaattaacaccaccggaggaggac
aagagagatatccggcaatctccaaagaggggcttcctccgctctgcctcactaggtcga
agggcctccttccacctggaatgtctgaagcgacagaagaatcaagggggagacatctct
cagaagacagtcctgcccttgcatctggttcatcatcaggcattggctgtggcaggcctg
agccccctcctccagagaagccattcccccagcacatcccccaggccctgtgccacccca
ccagccactccaggcagccgaggctggcccccacagcctatccccaccctgcggctggag
ggtgccgaatccaacgagaaactcaacagcagcttcccgtccatccactgcagctcctgg
tctggggagcccacaccctgtggtggaggtggcagcactatccggagagcccggccagtg
tccctcactgtgcccggccaggctggggcccagggcaggcagttccacggcagtgccagc
agcctggtagaagcggtcttgatttcagaaggactggggcagtttgctcaagatcccaag
tttattgaggtcacaacccaggagctggctgacgcctgtgacatgaccatagaggagatg
gagaacgccgcagacaacatcctcagtgggggcgcccagcagagccccaatggcacccta
ctacctttcgttaactgcagggacccagggcaggacagagcagagggccaagagggcgag
acctgcgcgcccaccctggcgtgtcggaagagcgaggaggagctccaggacagcagagcc
cacgtcggcagcctgtag
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integrated database retrieval system
