Leopardus geoffroyi (Geoffroy's cat): 123599308 Help Entry 123599308         CDS       T10761                                  Symbol CASP8 Name (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism lgf  Leopardus geoffroyi (Geoffroy's cat) Pathway lgf01524   Platinum drug resistance lgf04115   p53 signaling pathway lgf04210   Apoptosis lgf04215   Apoptosis - multiple species lgf04217   Necroptosis lgf04620   Toll-like receptor signaling pathway lgf04621   NOD-like receptor signaling pathway lgf04622   RIG-I-like receptor signaling pathway lgf04623   Cytosolic DNA-sensing pathway lgf04625   C-type lectin receptor signaling pathway lgf04657   IL-17 signaling pathway lgf04668   TNF signaling pathway lgf04932   Non-alcoholic fatty liver disease lgf04936   Alcoholic liver disease lgf05010   Alzheimer disease lgf05016   Huntington disease lgf05022   Pathways of neurodegeneration - multiple diseases lgf05132   Salmonella infection lgf05134   Legionellosis lgf05142   Chagas disease lgf05145   Toxoplasmosis lgf05152   Tuberculosis lgf05160   Hepatitis C lgf05161   Hepatitis B lgf05162   Measles lgf05163   Human cytomegalovirus infection lgf05164   Influenza A lgf05165   Human papillomavirus infection lgf05167   Kaposi sarcoma-associated herpesvirus infection lgf05168   Herpes simplex virus 1 infection lgf05169   Epstein-Barr virus infection lgf05170   Human immunodeficiency virus 1 infection lgf05200   Pathways in cancer lgf05203   Viral carcinogenesis lgf05416   Viral myocarditis lgf05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:lgf00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     123599308 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     123599308 (CASP8)    04215 Apoptosis - multiple species     123599308 (CASP8)    04217 Necroptosis     123599308 (CASP8)    04115 p53 signaling pathway     123599308 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     123599308 (CASP8)    04621 NOD-like receptor signaling pathway     123599308 (CASP8)    04622 RIG-I-like receptor signaling pathway     123599308 (CASP8)    04623 Cytosolic DNA-sensing pathway     123599308 (CASP8)    04625 C-type lectin receptor signaling pathway     123599308 (CASP8)    04657 IL-17 signaling pathway     123599308 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     123599308 (CASP8)    05203 Viral carcinogenesis     123599308 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     123599308 (CASP8)    05161 Hepatitis B     123599308 (CASP8)    05160 Hepatitis C     123599308 (CASP8)    05164 Influenza A     123599308 (CASP8)    05162 Measles     123599308 (CASP8)    05168 Herpes simplex virus 1 infection     123599308 (CASP8)    05163 Human cytomegalovirus infection     123599308 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     123599308 (CASP8)    05169 Epstein-Barr virus infection     123599308 (CASP8)    05165 Human papillomavirus infection     123599308 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     123599308 (CASP8)    05134 Legionellosis     123599308 (CASP8)    05152 Tuberculosis     123599308 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     123599308 (CASP8)    05142 Chagas disease     123599308 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     123599308 (CASP8)    05016 Huntington disease     123599308 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     123599308 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     123599308 (CASP8)    05416 Viral myocarditis     123599308 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     123599308 (CASP8)    04932 Non-alcoholic fatty liver disease     123599308 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     123599308 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:lgf01002]     123599308 (CASP8) Enzymes [BR:lgf01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      123599308 (CASP8) Peptidases and inhibitors [BR:lgf01002]  Cysteine peptidases   Family C14: caspase family    123599308 (CASP8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  123599308 NCBI-ProteinID:  XP_045336677 LinkDB All DBs Position C1:187572068..187598611 Genome browser AA seq 479 aa AA seqDB search MDFSKCLYNIGEQLGSDELASLKFLSLDYIPQKKQEPIKDALMLFQRLQEKRMLEESNLS FLKELLFRINRLDLLFNYLNTSKEVMEQELQIPGRAQIPPYRVMLFQISEDVNKLELRSF KFLLSQEISRCKVDDDMNLLDIFIEMEKRVILGERNLDTLKRICDQINKSLLKKITDYEE LSREGRMSLQRSPDELSNGEESLAMMALSDSLEEQDSESQTSDKVYRMKSKPRGYCLIFN NYDFSRARKDVPKLQNIKDRNGTNFDAEALSKTFSELHFEIVNFKDSTAKTICEVLKSYQ RMDHNNKDCFICCILSHGDKGIIYGSDGQEAPIYELTSYFTGSKCPSLAGKPKIFFIQAC QGDNYQRGIAVETDSEQKEDYLEMDSSFQKRYIPDEADFLLGMATVNNCVSYRNPTEGTW YIQSLCQSLRERCPRGEDILTILTEVNFEVSNKDDKKNMGKQMPQPTFTLRKKLFFPLN NT seq 1440 nt NT seq  +upstreamnt  +downstreamnt atggatttcagtaaatgtctgtataatattggggaacagctgggcagtgacgagctggcc tccctcaaattcctgagcctggactacatcccacaaaagaagcaagaacccatcaaagat gccttgatgttattccagagactccaggaaaagagaatgttggaggaaagcaacctgtcc ttcttgaaggagctgcttttccgaattaatagactggatctgctgttcaactacctgaac accagcaaggaagtgatggagcaggagcttcagataccaggcagagcccagatccctccc tacagggtcatgctttttcagatttcagaagatgtaaacaaattggaattgaggtcgttt aagtttcttttgagccaggagatctccagatgtaaagtggatgatgatatgaacttgctt gatattttcatagagatggaaaagagggtcatcctaggggaaagaaatttggacactctg aaaagaatctgtgaccaaatcaacaagagcctgctgaagaaaatcactgattatgaagaa ttaagcagagagggaagaatgagccttcaaagaagtccagatgaattgtcaaatggggag gaatccctggcaatgatggcattatcggactctctagaagaacaggacagtgagtcacag acatcggacaaagtttaccgaatgaaaagcaaacctcgcggatattgtttgatctttaac aattatgattttagcagagcacggaaggatgtgcccaaacttcagaacattaaggatagg aatggaacaaacttcgatgcagaagctttgagtaagacctttagtgagcttcattttgag attgtgaatttcaaagactctacagcaaagacaatctgtgaagttctgaaatcctaccaa agaatggaccataataacaaagattgcttcatctgctgtatcctctcccatggagacaaa ggcattatttatggctctgatgggcaggaagcccccatctatgagctgacttcttacttc actggttcaaagtgcccttcccttgcaggcaagcccaaaatcttttttattcaggcttgt caaggggataactaccagagaggtatagctgttgagactgactccgaacagaaggaagac tacttagaaatggactcatcatttcagaagagatatatcccagatgaagctgattttctg ctgggaatggccactgtgaacaactgtgtttcctaccgaaaccctacagaggggacctgg tatatccagtcactttgccagagcctaagagaaagatgtcctaggggcgaagatatcctc accatccttactgaggtgaactttgaagtgagcaataaggatgacaagaaaaacatgggg aaacaaatgccacaacctactttcacactgaggaaaaaactcttcttccctcttaattga

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